Danio rerio

31 known processes

tnni2a.4

troponin I, skeletal, fast 2a.4

(Aliases: hm:zehn0173,tropI-1d,tnni2,zgc:86800)

tnni2a.4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organelle assemblyGO:00709251100.966
actomyosin structure organizationGO:0031032530.964
myofibril assemblyGO:0030239480.962
cellular component assembly involved in morphogenesisGO:00109271070.957
muscle cell developmentGO:00550011150.939
striated muscle cell developmentGO:00550021080.922
muscle structure developmentGO:00610611960.912
muscle cell differentiationGO:00426921390.901
striated muscle cell differentiationGO:00511461290.887
regulation of nucleotide catabolic processGO:003081120.876
larval developmentGO:000216420.861
Worm
actin filament based processGO:0030029640.828
ribonucleoside monophosphate catabolic processGO:000915840.817
regulation of purine nucleotide catabolic processGO:003312120.801
muscle system processGO:0003012200.778
Human Worm
striated muscle tissue developmentGO:00147061100.747
Fly
actin cytoskeleton organizationGO:0030036630.741
cellular component morphogenesisGO:00329893360.728
heart processGO:0003015710.709
Fly
regulation of muscle contractionGO:000693730.708
heart morphogenesisGO:00030071560.707
purine nucleoside monophosphate catabolic processGO:000912840.702
cardiac muscle cell differentiationGO:0055007300.685
nucleoside monophosphate catabolic processGO:000912540.684
purine ribonucleoside monophosphate catabolic processGO:000916940.670
ventricular cardiac muscle tissue morphogenesisGO:005501020.641
atp catabolic processGO:000620040.633
sarcomere organizationGO:0045214260.629
Worm Fly
striated muscle myosin thick filament assemblyGO:007168860.610
skeletal muscle thin filament assemblyGO:003024040.606
cellular component assemblyGO:00226071700.595
regulation of nucleoside metabolic processGO:000911820.588
cytoskeleton organizationGO:0007010960.583
cellular component biogenesisGO:00440851780.579
heart developmentGO:00075073130.572
Fly
transmembrane transportGO:00550851200.564
somatic muscle developmentGO:000752540.557
cytokinesisGO:000091030.554
skeletal myofibril assemblyGO:001486670.515
heart contractionGO:0060047710.497
Fly
single organism organelle organizationGO:19025891990.485
muscle fiber developmentGO:0048747520.477
organelle organizationGO:00069962270.470
regulation of biological qualityGO:00650082630.461
Fly
regulation of hydrolase activityGO:0051336280.410
regulation of heart contractionGO:0008016320.408
regulation of system processGO:0044057400.408
generation of neuronsGO:00486993850.400
Worm
skeletal muscle tissue developmentGO:0007519670.397
Fly
cardiac cell developmentGO:0055006210.380
cellular biosynthetic processGO:00442492860.366
Human
neuron projection developmentGO:00311751800.362
Worm
system processGO:00030081850.358
Human Worm Fly
organic substance biosynthetic processGO:19015762890.354
Human
muscle contractionGO:0006936180.347
Human Worm
skeletal muscle contractionGO:000300950.346
Human
ion transportGO:00068111140.334
cytoskeleton dependent cytokinesisGO:006164030.306
neuron differentiationGO:00301823530.304
Worm
regulation of purine nucleotide metabolic processGO:1900542170.300
muscle organ developmentGO:00075171010.300
Fly
skeletal muscle organ developmentGO:0060538780.295
Fly
myosin filament organizationGO:003103360.286
ventricular cardiac muscle tissue developmentGO:000322930.285
cardiac muscle tissue developmentGO:0048738480.270
Fly
somitogenesisGO:0001756870.263
ventricular cardiac myofibril assemblyGO:005500540.258
ion transmembrane transportGO:0034220910.257
voluntary skeletal muscle contractionGO:000301040.221
morphogenesis of an epitheliumGO:00020093330.208
reproductionGO:0000003400.205
Worm
axonogenesisGO:00074091520.202
Worm
post embryonic morphogenesisGO:000988640.200
Worm
establishment of localizationGO:00512342440.199
homeostatic processGO:00425921420.198
Fly
regulation of blood circulationGO:1903522320.196
macromolecular complex assemblyGO:0065003350.189
skeletal muscle fiber developmentGO:0048741350.185
cellular amino acid biosynthetic processGO:000865220.183
actin filament based movementGO:003004810.182
cation homeostasisGO:0055080330.179
chordate embryonic developmentGO:00430092710.178
nitrogen compound metabolic processGO:00068073190.177
Human
cardiac muscle cell developmentGO:0055013200.175
maintenance of locationGO:005123540.175
muscle tissue developmentGO:00605371100.174
Fly
regulation of nucleotide metabolic processGO:0006140170.172
twitch skeletal muscle contractionGO:001472140.170
transportGO:00068102200.169
cardiocyte differentiationGO:0035051440.169
purine nucleotide metabolic processGO:0006163270.166
chemical homeostasisGO:0048878490.162
locomotionGO:00400113130.162
Worm
cation transportGO:0006812810.160
regulation of cellular metabolic processGO:00313233200.159
Human
cell projection organizationGO:00300302840.158
Worm
lipid storageGO:001991510.158
cellular macromolecular complex assemblyGO:0034622240.156
myosin filament assemblyGO:003103460.155
purine ribonucleoside monophosphate metabolic processGO:000916750.153
regulation of transmembrane transportGO:0034762180.153
locomotory behaviorGO:0007626340.143
directional locomotionGO:003305810.138
Worm
cardiac muscle tissue morphogenesisGO:005500870.137
blood circulationGO:0008015870.137
Fly
striated muscle contractionGO:0006941120.131
Human
fatty acid catabolic processGO:000906210.131
cellular protein complex assemblyGO:0043623190.127
organic substance catabolic processGO:1901575280.126
post embryonic organ developmentGO:004856940.123
heterocycle metabolic processGO:00464832900.121
Human
embryo development ending in birth or egg hatchingGO:00097922710.120
Worm
protein complex assemblyGO:0006461300.115
behaviorGO:0007610740.115
Worm
calcium ion homeostasisGO:0055074190.113
response to stressGO:00069502630.112
positive regulation of cellular catabolic processGO:003133130.112
regulation of muscle system processGO:009025750.111
positive regulation of transportGO:005105020.109
divalent inorganic cation homeostasisGO:0072507220.108
metal ion homeostasisGO:0055065260.107
adult behaviorGO:003053420.107
regulation of multicellular organismal processGO:00512392770.104
muscle organ morphogenesisGO:004864480.102
phosphorus metabolic processGO:00067931090.102
multi organism processGO:00517041340.102
Worm
somite developmentGO:0061053960.101
embryonic heart tube developmentGO:00350501330.099
multi organism reproductive processGO:0044703360.098
Worm
glycosyl compound metabolic processGO:1901657110.098
regulation of response to stimulusGO:00485832690.098
myotube differentiationGO:0014902450.098
mitotic cell cycle processGO:1903047480.097
reproductive processGO:0022414400.096
Worm
purine ribonucleotide metabolic processGO:0009150270.094
catabolic processGO:0009056320.092
actin filament organizationGO:0007015150.085
regulation of ion transmembrane transporter activityGO:003241220.084
single organism localizationGO:19025782250.084
protein complex biogenesisGO:0070271300.082
er nucleus signaling pathwayGO:000698420.081
organic cyclic compound metabolic processGO:19013603010.079
Human
cellular cation homeostasisGO:0030003170.079
ribonucleotide metabolic processGO:0009259270.075
heart loopingGO:0001947940.074
cellular nitrogen compound metabolic processGO:00346412900.074
Human
positive regulation of catabolic processGO:000989640.074
programmed cell deathGO:00125011190.072
anatomical structure homeostasisGO:0060249360.071
Fly
positive regulation of purine nucleotide catabolic processGO:003312310.070
regulation of metabolic processGO:00192223590.070
Human
positive regulation of nucleoside metabolic processGO:004597910.070
cardiac chamber developmentGO:0003205190.070
cell cycle processGO:0022402530.069
protein metabolic processGO:00195381830.069
protein complex subunit organizationGO:0071822460.068
cardiac ventricle developmentGO:000323190.068
signal transductionGO:00071654550.067
regulation of molecular functionGO:0065009700.066
regulation of reproductive processGO:200024140.066
reactive nitrogen species metabolic processGO:200105700.066
cell projection morphogenesisGO:00488582440.065
Worm
regulation of nitrogen compound metabolic processGO:00511712510.065
Human
regulation of striated muscle contractionGO:000694220.065
cell substrate adhesionGO:003158940.063
fatty acid oxidationGO:001939510.063
regulation of catalytic activityGO:0050790550.062
cell matrix adhesionGO:000716040.061
ribose phosphate metabolic processGO:0019693270.061
cardiac myofibril assemblyGO:005500390.060
single organism reproductive processGO:0044702400.059
Worm
response to chemicalGO:00422213200.059
embryonic heart tube morphogenesisGO:00031431080.058
slow twitch skeletal muscle fiber contractionGO:003144430.057
membrane repolarizationGO:008600920.057
gene expressionGO:00104672520.056
Human
metal ion transportGO:0030001580.056
regulation of ion transmembrane transportGO:0034765180.056
cell morphogenesis involved in differentiationGO:00009041950.055
Worm
regulation of nucleobase containing compound metabolic processGO:00192192500.055
Human
cellular catabolic processGO:0044248270.054
regulation of biosynthetic processGO:00098892500.054
Human
fatty acid beta oxidationGO:000663510.053
myotube cell developmentGO:0014904350.053
specification of symmetryGO:00097992040.052
purine containing compound metabolic processGO:0072521290.052
small molecule metabolic processGO:0044281770.051
divalent inorganic cation transportGO:0072511210.051
multicellular organismal movementGO:005087980.051
Human
circulatory system processGO:0003013870.050
Fly
cellular aromatic compound metabolic processGO:00067252950.049
Human
multicellular organismal reproductive processGO:0048609350.049
Worm
nucleotide metabolic processGO:0009117280.049
regulation of nitric oxide mediated signal transductionGO:001074910.049
cell divisionGO:0051301200.049
regulation of metal ion transportGO:001095940.048
immune system processGO:00023762410.048
aromatic compound catabolic processGO:0019439150.048
localization of cellGO:00516742440.047
macromolecule biosynthetic processGO:00090592270.047
Human
cardiac ventricle morphogenesisGO:000320870.047
rna metabolic processGO:00160702190.046
Human
single organism transportGO:00447652060.046
regulation of sequestering of calcium ionGO:005128240.045
cellular component movementGO:00069283350.045
developmental growthGO:00485891660.045
protein localization to nucleusGO:003450430.045
cellular nitrogen compound catabolic processGO:0044270150.045
agingGO:000756820.044
nucleobase containing small molecule metabolic processGO:0055086320.044
cellular response to topologically incorrect proteinGO:003596720.044
synaptic transmission cholinergicGO:000727140.044
endoplasmic reticulum unfolded protein responseGO:003096820.044
cell cell signalingGO:0007267520.044
nucleoside metabolic processGO:0009116110.043
cellular response to organic substanceGO:00713101050.042
sequestering of calcium ionGO:005120830.042
cellular metal ion homeostasisGO:0006875160.042
actin mediated cell contractionGO:007025210.041
purine ribonucleoside triphosphate metabolic processGO:000920590.040
cellular ion homeostasisGO:0006873170.040
cardiac chamber morphogenesisGO:0003206120.040
nucleobase containing compound metabolic processGO:00061392740.040
Human
response to activityGO:0014823140.040
regulation of transporter activityGO:003240920.040
axon developmentGO:00615641660.040
Worm
water homeostasisGO:003010440.039
hematopoietic stem cell differentiationGO:0060218200.039
cardiac muscle fiber developmentGO:004873930.039
organonitrogen compound metabolic processGO:1901564740.039
multicellular organism reproductionGO:0032504350.038
Worm
lymphoid lineage cell migrationGO:009753440.038
ventricular cardiac muscle cell differentiationGO:005501260.037
macromolecular complex subunit organizationGO:0043933740.037
regulation of primary metabolic processGO:00800903110.037
Human
cell motilityGO:00488702440.036
purine ribonucleoside metabolic processGO:0046128100.035
response to unfolded proteinGO:000698620.035
cell morphogenesis involved in neuron differentiationGO:00486671630.035
Worm
neuron neuron synaptic transmissionGO:000727010.035
regulation of transmembrane transporter activityGO:002289820.034
organic acid metabolic processGO:0006082310.034
muscle cell cellular homeostasisGO:004671650.034
Fly
macromolecule catabolic processGO:0009057150.033
embryonic organ morphogenesisGO:00485622740.033
neuromuscular synaptic transmissionGO:000727420.033
protein targeting to nucleusGO:004474430.032
ion homeostasisGO:0050801410.032
nucleoside phosphate metabolic processGO:0006753280.032
regulation of cell matrix adhesionGO:000195210.032
regulation of nucleic acid templated transcriptionGO:19035062130.031
Human
muscle tissue morphogenesisGO:006041570.031
cellular calcium ion homeostasisGO:0006874130.031
regulation of blood pressureGO:000821710.031
heterocycle catabolic processGO:0046700150.031
lipid oxidationGO:003444010.031
neuron developmentGO:00486662620.030
Worm
organic cyclic compound biosynthetic processGO:19013622230.030
Human
nucleobase containing compound catabolic processGO:0034655150.029
lymphoid lineage cell migration into thymusGO:009753540.029
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.029
feeding behaviorGO:000763150.029
Worm
cellular response to unfolded proteinGO:003462020.029
protein stabilizationGO:005082120.029
positive regulation of nucleotide catabolic processGO:003081310.028
nuclear divisionGO:0000280230.028
Fly
transcription dna templatedGO:00063511810.028
Human
reactive oxygen species metabolic processGO:007259360.028
cellular homeostasisGO:0019725260.028
Fly
organic cyclic compound catabolic processGO:1901361150.028
vasculature developmentGO:00019442780.027
cellular chemical homeostasisGO:0055082170.027
cellular divalent inorganic cation homeostasisGO:0072503130.027
inorganic cation transmembrane transportGO:0098662500.026
mitotic cell cycleGO:0000278640.026
synaptic growth at neuromuscular junctionGO:005112420.025
nucleocytoplasmic transportGO:000691340.025
venous blood vessel morphogenesisGO:004884530.025
small molecule catabolic processGO:004428230.025
regulation of multicellular organismal developmentGO:20000262230.025
pronephros developmentGO:0048793690.025
growth plate cartilage morphogenesisGO:000342210.024
canonical wnt signaling pathwayGO:0060070480.024
biosynthetic processGO:00090582940.024
Human
multicellular organism growthGO:003526440.024
regulation of calcium ion transportGO:005192420.024
nuclear transportGO:005116940.024
ribonucleoside metabolic processGO:0009119110.023
growthGO:00400071740.023
proteolysis involved in cellular protein catabolic processGO:005160330.023
regulation of macromolecule biosynthetic processGO:00105562250.023
Human
cytokinetic processGO:003250620.022
head developmentGO:00603223030.022
purine nucleoside triphosphate metabolic processGO:000914490.022
cellular localizationGO:0051641970.022
cellular lipid catabolic processGO:004424230.022
regulation of protein polymerizationGO:003227120.022
stem cell divisionGO:001714510.022
intracellular signal transductionGO:0035556850.021
response to oxygen containing compoundGO:1901700550.021
nucleic acid templated transcriptionGO:00976591810.021
Human
ribonucleoside triphosphate metabolic processGO:000919990.021
nuclear importGO:005117030.021
heterocycle biosynthetic processGO:00181302150.021
Human
regulation of organ growthGO:004662030.021
ribonucleoside monophosphate metabolic processGO:000916150.021
anterior posterior pattern specificationGO:00099521520.020
epithelial tube morphogenesisGO:00605621480.020
regulation of phosphorus metabolic processGO:0051174430.020
inorganic ion transmembrane transportGO:0098660570.020
ventricular cardiac muscle cell developmentGO:005501550.020
body morphogenesisGO:0010171160.020
Worm
negative regulation of gene expressionGO:0010629650.020
enzyme linked receptor protein signaling pathwayGO:00071671060.020
endocardial cushion formationGO:000327220.019
single organism cellular localizationGO:1902580460.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
Human
regulation of cellular component sizeGO:0032535300.019
reactive oxygen species biosynthetic processGO:190340910.019
atp metabolic processGO:004603450.019
purine ribonucleoside triphosphate catabolic processGO:000920760.019
single organism nuclear importGO:190259330.019
cation transmembrane transportGO:0098655650.019
tube morphogenesisGO:00352393490.019
carboxylic acid metabolic processGO:0019752220.019
regulation of membrane potentialGO:0042391230.019
regulation of rna biosynthetic processGO:20011412130.019
Human
kidney developmentGO:0001822920.018
atrial cardiac myofibril assemblyGO:005500420.018
phosphate containing compound metabolic processGO:00067961080.018
cellular macromolecule biosynthetic processGO:00346452240.018
Human
organophosphate metabolic processGO:0019637370.018
purine nucleoside metabolic processGO:0042278100.018
purine ribonucleotide catabolic processGO:000915460.018
positive regulation of biological processGO:00485182530.018
Human
alternative mrna splicing via spliceosomeGO:000038010.018
macromolecule localizationGO:0033036540.018
cellular macromolecule metabolic processGO:00442603910.018
Human
regulation of cellular biosynthetic processGO:00313262450.017
Human
axonal fasciculationGO:0007413110.017
organic acid catabolic processGO:001605430.017
gtp metabolic processGO:004603940.017
cell adhesionGO:0007155400.017
establishment of protein localization to organelleGO:007259440.017
purine nucleoside monophosphate metabolic processGO:000912650.017
regulation of growthGO:0040008420.017
cell migrationGO:00164772370.017
modification dependent macromolecule catabolic processGO:004363230.017
endocardial cushion morphogenesisGO:000320330.017
oxoacid metabolic processGO:0043436310.016
skeletal system morphogenesisGO:00487051020.016
regulation of protein import into nucleusGO:004230620.016
tissue homeostasisGO:0001894250.016
neuron recognitionGO:0008038180.016
wnt signaling pathwayGO:0016055800.016
growth plate cartilage developmentGO:000341720.016
sequestering of metal ionGO:005123830.016
inositol lipid mediated signalingGO:004801720.016
positive regulation of nitrogen compound metabolic processGO:0051173690.015
Human
biological adhesionGO:0022610400.015
carboxylic acid catabolic processGO:004639530.015
nitric oxide mediated signal transductionGO:000726320.015
nucleoside monophosphate metabolic processGO:000912360.015
response to heatGO:000940860.015
regulation of developmental processGO:00507932470.015
taxisGO:00423301090.014
hormone secretionGO:004687920.014
response to organic substanceGO:00100331530.014
embryonic cranial skeleton morphogenesisGO:0048701900.014
nucleoside triphosphate metabolic processGO:000914190.014
regulation of signalingGO:00230512350.014
determination of heart left right asymmetryGO:00613711170.014
regulation of transportGO:0051049450.014
regulation of catabolic processGO:0009894120.014
endochondral bone growthGO:000341620.014
regulation of protein complex disassemblyGO:004324410.014
regulation of cell developmentGO:00602841000.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
cardiac muscle contractionGO:006004860.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
purine ribonucleoside catabolic processGO:004613060.013
regulation of cell substrate adhesionGO:001081010.013
embryonic pattern specificationGO:0009880440.013
pole plasm assemblyGO:000731540.013
urogenital system developmentGO:0001655970.013
regulation of protein targetingGO:190353320.013
peptidyl serine phosphorylationGO:001810510.012
purine nucleotide catabolic processGO:000619560.012
embryonic organ developmentGO:00485683810.012
pharyngeal muscle developmentGO:004328240.012
protein import into nucleusGO:000660630.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
Human
cell morphogenesisGO:00009022890.012
Worm
organ growthGO:0035265120.012
regulation of ion transportGO:0043269220.012
regulation of alternative mrna splicing via spliceosomeGO:000038110.012
modification dependent protein catabolic processGO:001994130.012
nucleoside catabolic processGO:000916470.012
stem cell proliferationGO:007208940.012
regulation of cytoplasmic transportGO:190364940.012
regulation of heart rateGO:000202750.012
connective tissue developmentGO:0061448990.012
nucleobase containing compound biosynthetic processGO:00346542050.012
Human
protein polymerizationGO:005125840.012
regulation of behaviorGO:0050795240.012
apoptotic process involved in developmentGO:190274220.012
cellular amino acid metabolic processGO:000652070.012
determination of bilateral symmetryGO:00098552040.012
rna biosynthetic processGO:00327741810.011
Human
cytosolic calcium ion transportGO:006040130.011
developmental process involved in reproductionGO:0003006270.011
Worm
regulation of developmental growthGO:0048638380.011
nucleic acid metabolic processGO:00903042440.011
Human
nucleoside phosphate catabolic processGO:190129260.011
negative regulation of kinase activityGO:003367340.011
actin filament polymerizationGO:003004120.011
cellular macromolecule localizationGO:0070727210.011
cell surface receptor signaling pathwayGO:00071663250.011
mitotic cytokinesisGO:000028130.011
mitochondrion organizationGO:000700540.011
endocytosisGO:0006897160.011
response to abiotic stimulusGO:00096281220.011
carbohydrate derivative metabolic processGO:1901135610.011
posttranscriptional regulation of gene expressionGO:0010608140.011
negative regulation of metabolic processGO:0009892860.011
developmental cell growthGO:0048588520.010
negative regulation of cellular catabolic processGO:003133030.010
proteasomal protein catabolic processGO:001049820.010
rna localizationGO:000640340.010
regulation of heart growthGO:006042020.010
single organism metabolic processGO:00447102170.010

tnni2a.4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.302
Human
musculoskeletal system diseaseDOID:1700.302
Human
muscular diseaseDOID:008000000.265
Human
muscle tissue diseaseDOID:6600.265
Human
myopathyDOID:42300.145
cardiovascular system diseaseDOID:128700.145
heart diseaseDOID:11400.145
cardiomyopathyDOID:005070000.145
intrinsic cardiomyopathyDOID:006003600.128
hypertrophic cardiomyopathyDOID:1198400.079
dilated cardiomyopathyDOID:1293000.022
autosomal dominant nonsyndromic deafnessDOID:005056400.011
auditory system diseaseDOID:274200.011
sensory system diseaseDOID:005015500.011
nonsyndromic deafnessDOID:005056300.011
nervous system diseaseDOID:86300.011