IMP: Integrative Multi-species Prediction

Drosophila melanogaster

3 genes annotated in fly

regulation of excitatory postsynaptic membrane potential

Any process that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of excitatory postsynaptic membrane potential"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of excitatory postsynaptic membrane potential" (in gray)

Name	Description	Probability	Func Analog Organism
Nrx-1	Neurexin 1	0.670	Mouse
hiw	highwire	0.546
GluRIIA	Glutamate receptor IIA	0.498
CG32635	CG32635 gene product from transcript CG32635-RA	0.466
Ank2	Ankyrin 2	0.316
nwk	nervous wreck	0.267
CG34139	CG34139 gene product from transcript CG34139-RD	0.263	Human Rat
CrebB-17A	Cyclic-AMP response element binding protein B at 17A	0.196
brp	bruchpilot	0.185
CanA-14F	Calcineurin A at 14F	0.176	Mouse
stj	straightjacket	0.169
para	paralytic	0.165
Frq1	Frequenin 1	0.161
Octbeta2R	CG33976 gene product from transcript CG33976-RA	0.160
ST6Gal	Sialyltransferase	0.131
wit	wishful thinking	0.127
dnc	dunce	0.126
Tbh	Tyramine beta hydroxylase	0.125
tipE	temperature-induced paralytic E	0.112
rtGEF	rho-type guanine exchange factor	0.092
Frq2	Frequenin 2	0.091
nAcRalpha-30D	nicotinic Acetylcholine Receptor alpha 30D	0.090
Smg1	CG32743 gene product from transcript CG32743-RA	0.090
kcc	kazachoc	0.086
Ipp	Inositol polyphosphate 1-phosphatase	0.080
Drl-2	Derailed 2	0.080
Dat	Dopamine N acetyltransferase	0.079
Ih	I[[h]] channel	0.076
CG31146	CG31146 gene product from transcript CG31146-RD	0.073	Rat
CG33960	CG33960 gene product from transcript CG33960-RB	0.073
Alk	CG8250 gene product from transcript CG8250-RA	0.073
Syt1	Synaptotagmin 1	0.070
Trim9	CG31721 gene product from transcript CG31721-RB	0.069
jeb	jelly belly	0.069
Ace	Acetylcholine esterase	0.064
Oamb	Octopamine receptor in mushroom bodies	0.059
Sh	Shaker	0.058
CanA1	Calcineurin A1	0.057	Mouse
GluRIIB	Glutamate receptor IIB	0.057
CG42629	CG42629 gene product from transcript CG42629-RB	0.056
CG12187	CG12187 gene product from transcript CG12187-RA	0.055
Rim	CG33547 gene product from transcript CG33547-RB	0.053
rut	rutabaga	0.053
futsch	CG34387 gene product from transcript CG34387-RC	0.052
Hk	Hyperkinetic	0.051
nAcRalpha-80B	nicotinic Acetylcholine Receptor alpha 80B	0.048	Fly
gce	germ cell-expressed bHLH-PAS	0.046
mGluRA	metabotropic glutamate receptor	0.045
ewg	erect wing	0.044
wnd	wallenda	0.042
NaCP60E	Na channel protein 60E	0.042
synaptogyrin	CG10808 gene product from transcript CG10808-RA	0.041
Rab27	CG14791 gene product from transcript CG14791-RB	0.041
qvr	quiver	0.041
CG11317	CG11317 gene product from transcript CG11317-RA	0.041
dlg1	discs large 1	0.041	Rat
GluRIIE	Glutamate receptor IIE	0.040
Ca-alpha1T	CG15899 gene product from transcript CG15899-RC	0.039
NPFR1	neuropeptide F receptor	0.038
neuroligin	CG13772 gene product from transcript CG13772-RA	0.038	Human Mouse Rat
sif	still life	0.038
Oli	Olig family	0.038
rho-5	rhomboid-5	0.037
Cyp6g2	CG8859 gene product from transcript CG8859-RA	0.036
unc-104	CG8566 gene product from transcript CG8566-RB	0.036
Cdc42	CG12530 gene product from transcript CG12530-RA	0.036
Gycalpha99B	Guanylyl cyclase alpha-subunit at 99B	0.036
Dap160	Dynamin associated protein 160	0.035
CCKLR-17D1	CCK-like receptor at 17D1	0.035
dpr5	CG5308 gene product from transcript CG5308-RA	0.034
cac	cacophony	0.034
nAcRbeta-96A	nicotinic Acetylcholine Receptor beta 96A	0.032	Fly
CG12026	CG12026 gene product from transcript CG12026-RB	0.032
cv-c	crossveinless c	0.032
HDAC6	CG6170 gene product from transcript CG6170-RA	0.031
slo	slowpoke	0.031
Shal	Shaker cognate l	0.030
KaiRIA	CG18039 gene product from transcript CG18039-RA	0.030
CG43073	CG43073 gene product from transcript CG43073-RF	0.030
nAcRalpha-7E	nicotinic Acetylcholine Receptor alpha 7E	0.030	Fly
Dab	Disabled	0.030
Atg1	Autophagy-specific gene 1	0.028
Abl	Abl tyrosine kinase	0.028
GluRIIC	Glutamate receptor IIC	0.028
PIP5K59B	CG3682 gene product from transcript CG3682-RE	0.027
fd85E	forkhead domain 85E	0.027
Yp2	Yolk protein 2	0.026
VGlut	Vesicular glutamate transporter	0.026	Mouse
stnB	stoned B	0.026
Nmdar1	NMDA receptor 1	0.026
VAChT	CG32848 gene product from transcript CG32848-RA	0.026
Syn1	Syntrophin-like 1	0.026
mtt	mangetout	0.026
Cyp303a1	CG4163 gene product from transcript CG4163-RA	0.026
CG8117	CG8117 gene product from transcript CG8117-RA	0.025
Elp3	Elongator complex protein 3	0.025
Lrrk	Leucine-rich repeat kinase	0.025	Mouse
na	narrow abdomen	0.025
Fer2	48 related 2	0.024
tey	teyrha-meyrha	0.024
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.024
CG34400	CG34400 gene product from transcript CG34400-RD	0.024
AdoR	Adenosine receptor	0.024
CanB	Calcineurin B	0.024
trpml	transient receptor potential mucolipin	0.024
dpr8	CG32600 gene product from transcript CG32600-RA	0.023
Rya-r44F	Ryanodine receptor 44F	0.023
robo3	CG5423 gene product from transcript CG5423-RA	0.023
pAbp	polyA-binding protein	0.023
CG9437	CG9437 gene product from transcript CG9437-RA	0.022
fs(1)h	female sterile (1) homeotic	0.022
n-syb	n-synaptobrevin	0.022
Mical	Molecule interacting with CasL	0.022
ple	pale	0.022
tai	taiman	0.021
endoA	endophilin A	0.021
beat-IV	CG10152 gene product from transcript CG10152-RA	0.021
shep	alan shepard	0.021
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.021
Scgdelta	Sarcoglycan delta	0.021
Crz	Corazonin	0.021
Ca-beta	Ca2+-channel-protein-beta-subunit	0.021
plu	plutonium	0.020
alpha-catenin-related	alpha-catenin related	0.020
sr	stripe	0.020
Hr51	Hormone receptor 51	0.020
Lcch3	Ligand-gated chloride channel homolog 3	0.020
Rab5	Rab-protein 5	0.020
nau	nautilus	0.020
Pde11	Phosphodiesterase 11	0.020
Rdl	Resistant to dieldrin	0.020
dnr1	defense repressor 1	0.020
CG17922	CG17922 gene product from transcript CG17922-RA	0.020
Gr28b	Gustatory receptor 28b	0.019
X11Lbeta	CG32677 gene product from transcript CG32677-RA	0.019
Met	Methoprene-tolerant	0.019
CG3556	CG3556 gene product from transcript CG3556-RA	0.019
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.019
mp	multiplexin	0.019
pHCl	CG33989 gene product from transcript CG33989-RD	0.019
DAAM	Dishevelled Associated Activator of Morphogenesis	0.019
shakB	shaking B	0.019
CG11203	CG11203 gene product from transcript CG11203-RB	0.018
Eip75B	Ecdysone-induced protein 75B	0.018
Hs3st-A	Heparan sulfate 3-O sulfotransferase-A	0.018
CG1688	CG1688 gene product from transcript CG1688-RA	0.018
CG7058	CG7058 gene product from transcript CG7058-RB	0.018
CG30158	CG30158 gene product from transcript CG30158-RA	0.018
CG32432	CG32432 gene product from transcript CG32432-RA	0.018
sei	seizure	0.018
HisCl1	Histamine-gated chloride channel subunit 1	0.018
stmA	stambha A	0.018
kat-60L1	katanin p60-like 1	0.018
betaInt-nu	beta[nu] integrin	0.018
kay	kayak	0.018
pog	poor gastrulation	0.017
Aats-met	Methionyl-tRNA synthetase	0.017
Task6	CG9637 gene product from transcript CG9637-RC	0.017
Ilp5	Insulin-like peptide 5	0.017
CG10804	CG10804 gene product from transcript CG10804-RB	0.017
G9a	CG2995 gene product from transcript CG2995-RA	0.017
seq	sequoia	0.017
Muc91C	Mucin 91C	0.017
rpk	ripped pocket	0.017
CG10508	CG10508 gene product from transcript CG10508-RH	0.017
CG8959	CG8959 gene product from transcript CG8959-RA	0.016
Corin	CG2105 gene product from transcript CG2105-RB	0.016
Ets65A	Ets at 65A	0.016
oa2	octopamine receptor 2	0.016
Gr43a	Gustatory receptor 43a	0.016
bsk	basket	0.016
DJ-1alpha	CG6646 gene product from transcript CG6646-RA	0.016
Gad1	Glutamic acid decarboxylase 1	0.016
mnb	minibrain	0.016
CG8177	CG8177 gene product from transcript CG8177-RG	0.016
beat-VI	CG14064 gene product from transcript CG14064-RA	0.016
fend	forked end	0.016
beat-Vb	CG31298 gene product from transcript CG31298-RA	0.016
dpr14	CG10946 gene product from transcript CG10946-RA	0.015
CG42540	CG42540 gene product from transcript CG42540-RF	0.015
TyrR	Tyramine receptor	0.015
olf413	CG12673 gene product from transcript CG12673-RB	0.015
Syt4	Synaptotagmin 4	0.015
CG13253	CG13253 gene product from transcript CG13253-RB	0.015
Grip	Glutamate receptor binding protein	0.015
Med	Medea	0.015
CG34388	CG34388 gene product from transcript CG34388-RC	0.015
dpr11	CG33202 gene product from transcript CG33202-RB	0.015
CG6490	CG6490 gene product from transcript CG6490-RB	0.015
endoB	endophilin B	0.015
l(2)k16918	lethal (2) k16918	0.015
CG1308	CG1308 gene product from transcript CG1308-RE	0.014
Cpr65Eb	Cuticular protein 65Eb	0.014
osm-1	CG13809 gene product from transcript CG13809-RA	0.014
lmd	lame duck	0.014
Ilp2	Insulin-like peptide 2	0.014
plx	pollux	0.014
CG8214	CG8214 gene product from transcript CG8214-RA	0.014
Npc2c	Niemann-Pick type C-2c	0.014
CG14418	CG14418 gene product from transcript CG14418-RA	0.014
CG14441	CG14441 gene product from transcript CG14441-RA	0.014
Teh1	tipE homolog 1	0.014
CG6954	CG6954 gene product from transcript CG6954-RB	0.014
Irk3	Inwardly rectifying potassium channel 3	0.014
CG31221	CG31221 gene product from transcript CG31221-RA	0.014
Mob4	CG3403 gene product from transcript CG3403-RA	0.014
Rh6	Rhodopsin 6	0.014
CG13636	CG13636 gene product from transcript CG13636-RB	0.014
Clk	Clock	0.014
Aplip1	APP-like protein interacting protein 1	0.014	Mouse
spas	spastin	0.014
Syt12	Synaptotagmin 12	0.013
erm	earmuff	0.013
CG2126	CG2126 gene product from transcript CG2126-RA	0.013
per	period	0.013
CG12594	CG12594 gene product from transcript CG12594-RA	0.013
CG13404	CG13404 gene product from transcript CG13404-RB	0.013
ETHR	CG5911 gene product from transcript CG5911-RB	0.013
clumsy	CG8681 gene product from transcript CG8681-RB	0.013
ru	roughoid	0.013
cngl	CNG channel-like	0.013
HLH3B	Helix loop helix protein 3B	0.013
Ubx	Ultrabithorax	0.013
CG4194	CG4194 gene product from transcript CG4194-RA	0.013
CG10260	CG10260 gene product from transcript CG10260-RB	0.013
CG33988	CG33988 gene product from transcript CG33988-RA	0.013
CG3078	CG3078 gene product from transcript CG3078-RA	0.013
CG8455	CG8455 gene product from transcript CG8455-RA	0.013
lap	like-AP180	0.013
Teh2	tipE homolog 2	0.013
SK	small conductance calcium-activated potassium channel	0.013
TBPH	CG10327 gene product from transcript CG10327-RC	0.013
mura	murashka	0.013
CG3713	CG3713 gene product from transcript CG3713-RA	0.013
CG34362	CG34362 gene product from transcript CG34362-RD	0.013
GLaz	Glial Lazarillo	0.013
nAcRalpha-96Ab	nicotinic Acetylcholine Receptor alpha 96Ab	0.013	Fly
Syx6	Syntaxin 6	0.013
dpr12	CG34385 gene product from transcript CG34385-RC	0.013
CG12672	CG12672 gene product from transcript CG12672-RA	0.013
CG2225	CG2225 gene product from transcript CG2225-RC	0.013
CG14095	CG14095 gene product from transcript CG14095-RA	0.013
CG9335	CG9335 gene product from transcript CG9335-RA	0.013
CG11768	CG11768 gene product from transcript CG11768-RB	0.013
CG42784	CG42784 gene product from transcript CG42784-RE	0.012
NAT1	CG3845 gene product from transcript CG3845-RA	0.012
CG34354	CG34354 gene product from transcript CG34354-RA	0.012
CG15760	CG15760 gene product from transcript CG15760-RA	0.012
CG2993	CG2993 gene product from transcript CG2993-RA	0.012
CG12001	CG12001 gene product from transcript CG12001-RA	0.012
Plc21C	Phospholipase C at 21C	0.012
CG7565	CG7565 gene product from transcript CG7565-RA	0.012
CG8909	CG8909 gene product from transcript CG8909-RC	0.012
CanB2	Calcineurin B2	0.012
CG6765	CG6765 gene product from transcript CG6765-RA	0.012
dlp	dally-like	0.012
CG5890	CG5890 gene product from transcript CG5890-RB	0.012
GluClalpha	CG7535 gene product from transcript CG7535-RG	0.012
Hr46	Hormone receptor-like in 46	0.012
CG34370	CG34370 gene product from transcript CG34370-RG	0.012
simj	simjang	0.012
Fas2	Fasciclin 2	0.012
CG33958	CG33958 gene product from transcript CG33958-RA	0.012
CG14185	CG14185 gene product from transcript CG14185-RA	0.012
fas	faint sausage	0.012
CG8916	CG8916 gene product from transcript CG8916-RB	0.012
CG13362	CG13362 gene product from transcript CG13362-RA	0.012
Sytalpha	Synaptotagmin alpha	0.012
CG13650	CG13650 gene product from transcript CG13650-RB	0.012
CG10483	CG10483 gene product from transcript CG10483-RA	0.012
Vsx2	CG33980 gene product from transcript CG33980-RA	0.012
Nckx30C	CG18660 gene product from transcript CG18660-RD	0.012
CG13408	CG13408 gene product from transcript CG13408-RA	0.012
CG13594	CG13594 gene product from transcript CG13594-RA	0.012
Mip	Myoinhibiting peptide precursor	0.012
CG4133	CG4133 gene product from transcript CG4133-RA	0.012
unc79	CG5237 gene product from transcript CG5237-RB	0.012
CG8248	CG8248 gene product from transcript CG8248-RA	0.012
CG14358	CG14358 gene product from transcript CG14358-RB	0.012
Nach	CG8178 gene product from transcript CG8178-RA	0.012
mfr	misfire	0.012
CG5036	CG5036 gene product from transcript CG5036-RB	0.012
Cip4	CG15015 gene product from transcript CG15015-RA	0.012
CG13108	CG13108 gene product from transcript CG13108-RA	0.012
slou	slouch	0.012
stg1	stargazin-like protein	0.012
CG2278	CG2278 gene product from transcript CG2278-RA	0.012
CG4467	CG4467 gene product from transcript CG4467-RB	0.012
sick	sickie	0.012
CG15236	CG15236 gene product from transcript CG15236-RB	0.012
CG42248	CG42248 gene product from transcript CG42248-RD	0.012
CG32809	CG32809 gene product from transcript CG32809-RD	0.011
CG12158	CG12158 gene product from transcript CG12158-RA	0.011
CG8927	CG8927 gene product from transcript CG8927-RA	0.011
CG15765	CG15765 gene product from transcript CG15765-RA	0.011
CG5844	CG5844 gene product from transcript CG5844-RA	0.011
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.011
CG11347	CG11347 gene product from transcript CG11347-RE	0.011
CG12402	CG12402 gene product from transcript CG12402-RA	0.011
Vsx1	CG4136 gene product from transcript CG4136-RA	0.011
Doc3	Dorsocross3	0.011
CG7166	CG7166 gene product from transcript CG7166-RB	0.011
CG33543	CG33543 gene product from transcript CG33543-RC	0.011
CG15704	CG15704 gene product from transcript CG15704-RA	0.011
Glu-RI	Glutamate receptor I	0.011
CG8795	CG8795 gene product from transcript CG8795-RC	0.011
CG3009	CG3009 gene product from transcript CG3009-RA	0.011
Trf4-1	CG11265 gene product from transcript CG11265-RE	0.011
CG10147	CG10147 gene product from transcript CG10147-RA	0.011
dpr6	CG14162 gene product from transcript CG14162-RA	0.011
Taspase1	Taspase 1	0.011
CG9760	CG9760 gene product from transcript CG9760-RC	0.011
star1	allatostatin C receptor 1	0.011
Smyd4	SET and MYND domain protein 4	0.011
CG3104	CG3104 gene product from transcript CG3104-RA	0.011
CG14024	CG14024 gene product from transcript CG14024-RA	0.011
hig	hikaru genki	0.011
CG17193	CG17193 gene product from transcript CG17193-RB	0.011
CG16779	CG16779 gene product from transcript CG16779-RA	0.011
fln	flightin	0.011
CG10362	CG10362 gene product from transcript CG10362-RA	0.011
CG13073	CG13073 gene product from transcript CG13073-RB	0.011
Ork1	Open rectifier K[+] channel 1	0.011
eg	eagle	0.011
CG18437	CG18437 gene product from transcript CG18437-RB	0.011
dpr10	CG32057 gene product from transcript CG32057-RB	0.011
CG7056	CG7056 gene product from transcript CG7056-RA	0.011
CG13050	CG13050 gene product from transcript CG13050-RA	0.011
Act57B	Actin 57B	0.011
CG2052	CG2052 gene product from transcript CG2052-RB	0.011
CG7248	CG7248 gene product from transcript CG7248-RA	0.011
DopR	Dopamine receptor	0.011
Pkc98E	Protein C kinase 98E	0.011
CG10251	CG10251 gene product from transcript CG10251-RB	0.011
CG14372	CG14372 gene product from transcript CG14372-RC	0.011
Mlp84B	Muscle LIM protein at 84B	0.011
pyx	pyrexia	0.011
Toll-9	CG5528 gene product from transcript CG5528-RA	0.011
CG5621	CG5621 gene product from transcript CG5621-RA	0.011
CG17184	CG17184 gene product from transcript CG17184-RB	0.011
Rx	Retinal Homeobox	0.011
CG9170	CG9170 gene product from transcript CG9170-RB	0.011
CG33289	CG33289 gene product from transcript CG33289-RA	0.011
CG9339	CG9339 gene product from transcript CG9339-RG	0.011
CG8216	CG8216 gene product from transcript CG8216-RA	0.011
CG14431	CG14431 gene product from transcript CG14431-RB	0.011
CG9395	CG9395 gene product from transcript CG9395-RB	0.011
sha	shavenoid	0.011
mspo	M-spondin	0.011
Npc1b	Niemann-Pick type C-1b	0.011
CG15465	CG15465 gene product from transcript CG15465-RA	0.010
CG12912	CG12912 gene product from transcript CG12912-RA	0.010
CG2217	CG2217 gene product from transcript CG2217-RA	0.010
slp1	sloppy paired 1	0.010
CG13293	CG13293 gene product from transcript CG13293-RA	0.010
CG14274	CG14274 gene product from transcript CG14274-RA	0.010
Mpp6	M-phase phosphoprotein 6	0.010
CG4017	CG4017 gene product from transcript CG4017-RA	0.010
CG15537	CG15537 gene product from transcript CG15537-RB	0.010
CG12836	CG12836 gene product from transcript CG12836-RA	0.010
CG42683	CG42683 gene product from transcript CG42683-RA	0.010
mei-W68	meiotic W68	0.010
gprs	CG18471 gene product from transcript CG18471-RA	0.010
CG6026	CG6026 gene product from transcript CG6026-RB	0.010
CG32532	CG32532 gene product from transcript CG32532-RA	0.010
CG18005	CG18005 gene product from transcript CG18005-RA	0.010
CG9733	CG9733 gene product from transcript CG9733-RA	0.010
bru-3	bruno-3	0.010
Cpr30F	Cuticular protein 30F	0.010
Or33c	Odorant receptor 33c	0.010
CG13198	CG13198 gene product from transcript CG13198-RA	0.010
CG32135	CG32135 gene product from transcript CG32135-RA	0.010
CG18095	CG18095 gene product from transcript CG18095-RB	0.010
pdm2	POU domain protein 2	0.010
CG5984	CG5984 gene product from transcript CG5984-RA	0.010
CG15522	CG15522 gene product from transcript CG15522-RA	0.010
etaTry	etaTrypsin	0.010
Pxd	Peroxidase	0.010
CG10132	CG10132 gene product from transcript CG10132-RA	0.010
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.010
CG4587	CG4587 gene product from transcript CG4587-RD	0.010
ppk25	pickpocket 25	0.010
CG13897	CG13897 gene product from transcript CG13897-RA	0.010
Gr39a	Gustatory receptor 39a	0.010
CG6044	CG6044 gene product from transcript CG6044-RA	0.010
Ir25a	Ionotropic receptor 25a	0.010
CG12344	CG12344 gene product from transcript CG12344-RA	0.010
sens-2	senseless-2	0.010
CG12605	CG12605 gene product from transcript CG12605-RB	0.010
CG12541	CG12541 gene product from transcript CG12541-RD	0.010
CG15307	CG15307 gene product from transcript CG15307-RA	0.010
nullo	CG14426 gene product from transcript CG14426-RB	0.010
Dh	Diuretic hormone	0.010
tap	target of Poxn	0.010
lbm	late bloomer	0.010
CG12075	CG12075 gene product from transcript CG12075-RB	0.010
Tsp26A	Tetraspanin 26A	0.010
elk	eag-like K[+] channel	0.010
Tehao	CG7121 gene product from transcript CG7121-RA	0.010
CG14047	CG14047 gene product from transcript CG14047-RH	0.010
daw	dawdle	0.010
CG8910	CG8910 gene product from transcript CG8910-RA	0.010