IMP: Integrative Multi-species Prediction

Drosophila melanogaster

27 genes annotated in fly

regulation of actin polymerization or depolymerization

Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of actin polymerization or depolymerization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of actin polymerization or depolymerization" (in gray)

Name	Description	Probability	Func Analog Organism
chic	chickadee	0.994
cpb	capping protein beta	0.872
Vrp1	Verprolin 1	0.811
katanin-60	katanin 60	0.794
twf	twinfilin	0.777
Arc-p34	CG10954 gene product from transcript CG10954-RA	0.768	Human
WASp	CG1520 gene product from transcript CG1520-RA	0.731
Arp66B	Actin-related protein 66B	0.728	Human Yeast Worm
robo	roundabout	0.721
Rala	Ras-related protein	0.709
Abi	Abelson interacting protein	0.691	Human
bif	bifocal	0.678
trc	tricornered	0.661
par-1	CG8201 gene product from transcript CG8201-RA	0.615
mbc	myoblast city	0.597
Cdc42	CG12530 gene product from transcript CG12530-RA	0.576
Rac1	CG2248 gene product from transcript CG2248-RA	0.557	Mouse Fly
flw	flapwing	0.527
cindr	CIN85 and CD2AP orthologue	0.512
Rho1	CG8416 gene product from transcript CG8416-RB	0.490
msn	misshapen	0.429
Chc	Clathrin heavy chain	0.404
p120ctn	Adherens junction protein p120	0.397
usp	ultraspiracle	0.392
spas	spastin	0.382
ena	enabled	0.365	Mouse
S6k	RPS6-p70-protein kinase	0.360
zip	zipper	0.350
Sra-1	specifically Rac1-associated protein 1	0.345
Rab11	Rab-protein 11	0.343
Hem	HEM-protein	0.337	Mouse
Arp14D	Actin-related protein 14D	0.332	Human Yeast Worm
baz	bazooka	0.317
rok	Rho-kinase	0.297	Fly
sls	sallimus	0.293
Cortactin	CG3637 gene product from transcript CG3637-RA	0.272
Akt1	CG4006 gene product from transcript CG4006-RA	0.270
par-6	CG5884 gene product from transcript CG5884-RA	0.239
sn	singed	0.197
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.187
egh	egghead	0.175
numb	CG3779 gene product from transcript CG3779-RB	0.174
cta	concertina	0.169
Mtl	Mig-2-like	0.169	Fly
BicD	Bicaudal D	0.167
sqh	spaghetti squash	0.167
Cip4	CG15015 gene product from transcript CG15015-RA	0.166
Dap160	Dynamin associated protein 160	0.159
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.151
spir	spire	0.144
shot	short stop	0.143
pod1	CG4532 gene product from transcript CG4532-RF	0.138	Yeast
egl	egalitarian	0.136
CkIIbeta	Casein kinase II beta subunit	0.135
capu	cappuccino	0.132
Actn	alpha actinin	0.123
Sos	Son of sevenless	0.121
rst	roughest	0.120	Mouse
trio	CG18214 gene product from transcript CG18214-RA	0.117	Worm
Mob2	CG11711 gene product from transcript CG11711-RC	0.113
lace	CG4162 gene product from transcript CG4162-RA	0.105
G-oalpha47A	G protein oalpha 47A	0.100
rap	retina aberrant in pattern	0.100
RhoGAP92B	CG4755 gene product from transcript CG4755-RA	0.097
Atg1	Autophagy-specific gene 1	0.097
Lis-1	Lissencephaly-1	0.097
dsh	dishevelled	0.094
cora	coracle	0.091
ttk	tramtrack	0.090
hts	hu li tai shao	0.088	Human
how	held out wings	0.087
cpa	capping protein alpha	0.086
Mrtf	Myocardin-related transcription factor	0.085
Dlic	Dynein light intermediate chain	0.084
stai	stathmin	0.083
crb	crumbs	0.082
kirre	kin of irre	0.081
da	daughterless	0.080
rin	rasputin	0.079
Ptp69D	Protein tyrosine phosphatase 69D	0.079
Zasp66	Z band alternatively spliced PDZ-motif protein 66	0.079
Pak3	CG14895 gene product from transcript CG14895-RA	0.078
Arf51F	ADP ribosylation factor 51F	0.075	Human
Vang	Van Gogh	0.074
kuz	kuzbanian	0.074
tsr	twinstar	0.074	Worm
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.073
sns	sticks and stones	0.073	Mouse
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.073
wts	warts	0.072	Human
kel	kelch	0.071
Pk61C	Protein kinase 61C	0.069
klar	klarsicht	0.069
gig	gigas	0.068
Sop2	Suppressor of profilin 2	0.066	Human Yeast
flr	flare	0.066
futsch	CG34387 gene product from transcript CG34387-RC	0.065
Shc	SHC-adaptor protein	0.064
babo	baboon	0.063
X11L	CG5675 gene product from transcript CG5675-RB	0.061
Prm	Paramyosin	0.061
exba	extra bases	0.060
CG10641	CG10641 gene product from transcript CG10641-RA	0.055
rhea	CG6831 gene product from transcript CG6831-RA	0.055
vav	CG7893 gene product from transcript CG7893-RB	0.053
hbs	hibris	0.052	Mouse
Arc-p20	CG5972 gene product from transcript CG5972-RA	0.052
shg	shotgun	0.052
RhoGEF2	CG9635 gene product from transcript CG9635-RF	0.051
CG32556	CG32556 gene product from transcript CG32556-RB	0.050
mts	microtubule star	0.050
Rac2	CG8556 gene product from transcript CG8556-RA	0.050	Mouse Fly
plexA	plexin A	0.050
drpr	draper	0.049
Rab6	Rab-protein 6	0.048
Rab7	Rab-protein 7	0.048
CG8578	CG8578 gene product from transcript CG8578-RA	0.048
ex	expanded	0.047
Acsl	Acyl-CoA synthetase long-chain	0.047
Act57B	Actin 57B	0.046
Mlc2	Myosin light chain 2	0.046
pcs	parcas	0.046
LanA	Laminin A	0.045
Rab23	CG2108 gene product from transcript CG2108-RA	0.044
Ten-m	Tenascin major	0.044
sec5	CG8843 gene product from transcript CG8843-RA	0.043
mys	myospheroid	0.043
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.042
sav	salvador	0.042
Ced-12	CG5336 gene product from transcript CG5336-RA	0.041
htl	heartless	0.040
dock	dreadlocks	0.040	Human Mouse
not	non-stop	0.040
Mlc-c	Myosin light chain cytoplasmic	0.040
robo3	CG5423 gene product from transcript CG5423-RA	0.038
HSPC300	CG30173 gene product from transcript CG30173-RA	0.038
Rab5	Rab-protein 5	0.038
Jra	Jun-related antigen	0.038
Lasp	CG3849 gene product from transcript CG3849-RB	0.036
Pak	PAK-kinase	0.034	Human
brat	brain tumor	0.034
ik2	IkappaB kinase-like 2	0.034
RASSF8	CG5053 gene product from transcript CG5053-RA	0.034
Mical	Molecule interacting with CasL	0.034
mats	mob as tumor suppressor	0.033
srp	serpent	0.033
scb	scab	0.032
Syx1A	Syntaxin 1A	0.032
caz	cabeza	0.032
DAAM	Dishevelled Associated Activator of Morphogenesis	0.032
Pvr	PDGF- and VEGF-receptor related	0.032
wdb	widerborst	0.032
bsk	basket	0.032
Alk	CG8250 gene product from transcript CG8250-RA	0.030
alpha-Adaptin	CG4260 gene product from transcript CG4260-RA	0.030
Atpalpha	Na pump alpha subunit	0.030
ttv	tout-velu	0.030
blow	blown fuse	0.030
ck	crinkled	0.030
spen	split ends	0.029
Dcr-2	Dicer-2	0.029
Brca2	Breast cancer 2, early onset homolog	0.029
dos	daughter of sevenless	0.029
l(2)gl	lethal (2) giant larvae	0.028
lig	lingerer	0.028
CG11299	CG11299 gene product from transcript CG11299-RA	0.028
Eps-15	Epidermal growth factor receptor pathway substrate clone 15	0.027
hpo	hippo	0.027
CG31224	CG31224 gene product from transcript CG31224-RA	0.027
Tak1	TGF-beta activated kinase 1	0.026
endoA	endophilin A	0.026
jar	jaguar	0.026
trr	trithorax-related	0.026
zfh1	Zn finger homeodomain 1	0.025
Src64B	Src oncogene at 64B	0.025
rols	rolling pebbles	0.025
stan	starry night	0.025
Eph	Eph receptor tyrosine kinase	0.025
step	steppke	0.025
luna	CG33473 gene product from transcript CG33473-RB	0.025
Tig	Tiggrin	0.024
cdi	center divider	0.024
pyd	polychaetoid	0.024
sty	sprouty	0.024
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.024
Ephrin	CG1862 gene product from transcript CG1862-RA	0.024
Hph	HIF prolyl hydroxylase	0.024
dlg1	discs large 1	0.023	Mouse
Rme-8	Receptor mediated endocytosis 8	0.023
tomosyn	CG17762 gene product from transcript CG17762-RB	0.023
Sh3beta	CG8582 gene product from transcript CG8582-RD	0.023
alpha-Spec	alpha Spectrin	0.023
nos	nanos	0.022
exo84	CG6095 gene product from transcript CG6095-RA	0.022
klg	klingon	0.022
aop	anterior open	0.022
Gef26	CG9491 gene product from transcript CG9491-RB	0.022
S6kII	RPS6-protein kinase-II	0.021
Top3beta	Topoisomerase 3beta	0.021
CG12112	CG12112 gene product from transcript CG12112-RA	0.021
CG5447	CG5447 gene product from transcript CG5447-RA	0.021
tai	taiman	0.021
mib2	mind bomb 2	0.021
synj	synaptojanin	0.021
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.021
shrb	shrub	0.021
pll	pelle	0.020
otk	off-track	0.020
CrebA	Cyclic-AMP response element binding protein A	0.020
btz	barentsz	0.020
Hip14	Huntingtin-interacting protein 14	0.020
fra	frazzled	0.019
mmy	mummy	0.019
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.019
MED24	Mediator complex subunit 24	0.019
beta-Spec	beta Spectrin	0.019
CG17082	CG17082 gene product from transcript CG17082-RD	0.019
alpha-Cat	alpha Catenin	0.019
Dad	Daughters against dpp	0.019
Nrx-IV	Neurexin IV	0.019
Tom34	Translocase of outer membrane 34	0.019
twin	CG31137 gene product from transcript CG31137-RB	0.019
Pen	Pendulin	0.019
CG5741	CG5741 gene product from transcript CG5741-RC	0.018
RanBPM	Ran-binding protein M	0.018
fray	frayed	0.018
lqfR	liquid facets-Related	0.018
fry	furry	0.018
Peb	Protein ejaculatory bulb	0.018
RhoGAPp190	CG32555 gene product from transcript CG32555-RB	0.018
Marf	Mitochondrial assembly regulatory factor	0.017
sbr	small bristles	0.017
sqz	squeeze	0.017
Nrg	Neuroglian	0.017
Gos28	CG7700 gene product from transcript CG7700-RA	0.017
ovo	CG6824 gene product from transcript CG6824-RE	0.017
sano	serrano	0.017
vri	vrille	0.017
Pkn	Protein kinase related to protein kinase N	0.017
Abl	Abl tyrosine kinase	0.017
up	upheld	0.017
p16-ARC	CG9881 gene product from transcript CG9881-RA	0.016
jim	CG11352 gene product from transcript CG11352-RB	0.016
eff	effete	0.016
pigs	pickled eggs	0.016
lilli	lilliputian	0.016
CG4030	CG4030 gene product from transcript CG4030-RA	0.016
puc	puckered	0.016
Wnk	CG7177 gene product from transcript CG7177-RA	0.016
sws	swiss cheese	0.016
HmgD	High mobility group protein D	0.016
CadN	Cadherin-N	0.016
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.016
Pabp2	CG2163 gene product from transcript CG2163-RA	0.016
Mlc1	Myosin alkali light chain 1	0.016
gho	ghost	0.015
Tm2	Tropomyosin 2	0.015	Rat Worm
wun	wunen	0.015
Sox14	Sox box protein 14	0.015
CanB2	Calcineurin B2	0.015
wb	wing blister	0.015
l(1)G0469	lethal (1) G0469	0.015
Amph	Amphiphysin	0.015
mi	minus	0.015
mbt	mushroom bodies tiny	0.015
dsd	distracted	0.015
Tao-1	CG14217 gene product from transcript CG14217-RF	0.015
CG31048	CG31048 gene product from transcript CG31048-RB	0.015
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.014
Cul-3	Cullin-3	0.014
mwh	multiple wing hairs	0.014
bchs	blue cheese	0.014
CG9650	CG9650 gene product from transcript CG9650-RG	0.014
fas	faint sausage	0.014
Glt	Glutactin	0.014
CG10413	CG10413 gene product from transcript CG10413-RA	0.014
didum	dilute class unconventional myosin	0.014
jeb	jelly belly	0.014
CG1890	CG1890 gene product from transcript CG1890-RA	0.014
trn	tartan	0.014
Apc	APC-like	0.014
rut	rutabaga	0.014
Sin1	SAPK-interacting protein 1	0.014
lmd	lame duck	0.014
CG1021	CG1021 gene product from transcript CG1021-RE	0.014
l(1)G0148	lethal (1) G0148	0.014
Act5C	Actin 5C	0.014
stau	staufen	0.013
Mhc	Myosin heavy chain	0.013
CG3573	CG3573 gene product from transcript CG3573-RA	0.013
dgo	diego	0.013
pfk	piefke	0.013
Rbsn-5	Rabenosyn-5	0.013
SH3PX1	CG6757 gene product from transcript CG6757-RA	0.013
Wnt5	Wnt oncogene analog 5	0.013
enc	encore	0.013
pum	pumilio	0.013
Mp20	Muscle protein 20	0.013
arm	armadillo	0.013
cher	cheerio	0.013
spz	spatzle	0.013
nvy	nervy	0.013
Top3alpha	Topoisomerase 3alpha	0.013
Gem3	Gemin3	0.012
c11.1	CG12132 gene product from transcript CG12132-RA	0.012
sec23	CG1250 gene product from transcript CG1250-RA	0.012
PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	0.012
Syb	Synaptobrevin	0.012
Hrb87F	Heterogeneous nuclear ribonucleoprotein at 87F	0.012
CG10083	CG10083 gene product from transcript CG10083-RA	0.012
Fhos	CG42610 gene product from transcript CG42610-RC	0.012
cnc	cap-n-collar	0.012
slou	slouch	0.012
pcx	pecanex	0.012
fz	frizzled	0.011
Act88F	Actin 88F	0.011
CG5869	CG5869 gene product from transcript CG5869-RA	0.011	Yeast
Caki	Calcium/calmodulin-dependent protein kinase	0.011
RhoGAP15B	CG4937 gene product from transcript CG4937-RC	0.011
Nmnat	Nicotinamide mononucleotide adenylyltransferase	0.011
fwd	four wheel drive	0.011
rl	rolled	0.011
stc	shuttle craft	0.011
kon	kon-tiki	0.011
mirr	mirror	0.011
CG5694	CG5694 gene product from transcript CG5694-RA	0.011
capt	capulet	0.010
Mcr	Macroglobulin complement-related	0.010
Rya-r44F	Ryanodine receptor 44F	0.010
sina	seven in absentia	0.010
kermit	CG11546 gene product from transcript CG11546-RB	0.010
Stim	Stromal interaction molecule	0.010
in	inturned	0.010
nwk	nervous wreck	0.010
tipE	temperature-induced paralytic E	0.010
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.010
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.010
CalpB	Calpain-B	0.010
wupA	wings up A	0.010
Pi3K21B	CG2699 gene product from transcript CG2699-RA	0.010
gish	gilgamesh	0.010
foxo	forkhead box, sub-group O	0.010
pnt	pointed	0.010
CG31352	CG31352 gene product from transcript CG31352-RA	0.010
CG15658	CG15658 gene product from transcript CG15658-RA	0.010