IMP: Integrative Multi-species Prediction

Drosophila melanogaster

46 genes annotated in fly

myotube differentiation

The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "myotube differentiation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "myotube differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Vrp1	Verprolin 1	0.996
InR	Insulin-like receptor	0.979
Pax	Paxillin	0.977
rols	rolling pebbles	0.959
hbs	hibris	0.956
Mp20	Muscle protein 20	0.956
mbc	myoblast city	0.954
S6k	RPS6-p70-protein kinase	0.951
sns	sticks and stones	0.950
Rac2	CG8556 gene product from transcript CG8556-RA	0.944	Fly
wg	wingless	0.934	Mouse
Arp66B	Actin-related protein 66B	0.932
blow	blown fuse	0.924
Pglym78	Phosphoglyceromutase	0.918
pfk	piefke	0.914
sls	sallimus	0.855
foxo	forkhead box, sub-group O	0.836
pan	pangolin	0.835
rst	roughest	0.804	Fly
Thor	CG8846 gene product from transcript CG8846-RA	0.796
Tm2	Tropomyosin 2	0.792
Act57B	Actin 57B	0.706
siz	schizo	0.663
CanB2	Calcineurin B2	0.647
egh	egghead	0.606
LamC	Lamin C	0.587
kirre	kin of irre	0.579
PyK	Pyruvate kinase	0.551
slou	slouch	0.550
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.538
ptc	patched	0.530
Tpi	Triose phosphate isomerase	0.505
drk	downstream of receptor kinase	0.488
Rya-r44F	Ryanodine receptor 44F	0.442	Mouse
WASp	CG1520 gene product from transcript CG1520-RA	0.433
Pgk	Phosphoglycerate kinase	0.405
so	sine oculis	0.404	Zebrafish Fly
zfh1	Zn finger homeodomain 1	0.380
eve	even skipped	0.375
nej	nejire	0.375
p120ctn	Adherens junction protein p120	0.374
Mlp84B	Muscle LIM protein at 84B	0.374
myoglianin	CG1838 gene product from transcript CG1838-RD	0.359
Rala	Ras-related protein	0.339
stck	steamer duck	0.322
pnt	pointed	0.314
nau	nautilus	0.310	Human Zebrafish Mouse
HLH54F	CG5005 gene product from transcript CG5005-RA	0.293
hth	homothorax	0.289
Mef2	Myocyte enhancer factor 2	0.275
arm	armadillo	0.266
CG9090	CG9090 gene product from transcript CG9090-RA	0.260
pcs	parcas	0.257
Nrg	Neuroglian	0.238
ara	araucan	0.236
G-oalpha47A	G protein oalpha 47A	0.235
CG5177	CG5177 gene product from transcript CG5177-RA	0.233
Pp2B-14D	Protein phosphatase 2B at 14D	0.228	Mouse
babo	baboon	0.228
lbe	ladybird early	0.217
Hem	HEM-protein	0.216
bin	biniou	0.210
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.205
ttk	tramtrack	0.198
mib2	mind bomb 2	0.192
htl	heartless	0.166
bib	big brain	0.165
Antp	Antennapedia	0.163
Mlc1	Myosin alkali light chain 1	0.160
Poxm	Pox meso	0.150
en	engrailed	0.147
imd	immune deficiency	0.143
Cul-3	Cullin-3	0.141
Pak3	CG14895 gene product from transcript CG14895-RA	0.139
kn	knot	0.138
Sdc	Syndecan	0.138
Argk	Arginine kinase	0.137
norpA	no receptor potential A	0.137
Ric	Ras which interacts with Calmodulin	0.136
kon	kon-tiki	0.134
lmd	lame duck	0.134
Mf	Myofilin	0.131
CG7998	CG7998 gene product from transcript CG7998-RA	0.131
pb	proboscipedia	0.122
Ras85D	Ras oncogene at 85D	0.119
Rho1	CG8416 gene product from transcript CG8416-RB	0.118
gro	groucho	0.115
Abi	Abelson interacting protein	0.115
Arf51F	ADP ribosylation factor 51F	0.110
alpha-Adaptin	CG4260 gene product from transcript CG4260-RA	0.107
inv	invected	0.106
sim	single-minded	0.105
dac	dachshund	0.104
Cdc42	CG12530 gene product from transcript CG12530-RA	0.103	Fly
cno	canoe	0.101
GLaz	Glial Lazarillo	0.099
shn	schnurri	0.097
Dad	Daughters against dpp	0.093
Mad	Mothers against dpp	0.093
p38b	CG7393 gene product from transcript CG7393-RA	0.092	Mouse
sr	stripe	0.091
Myd88	CG2078 gene product from transcript CG2078-RA	0.091
dm	diminutive	0.088
vav	CG7893 gene product from transcript CG7893-RB	0.086
mys	myospheroid	0.086
Ubx	Ultrabithorax	0.084
Parp	Poly-(ADP-ribose) polymerase	0.084
Vang	Van Gogh	0.081
Egfr	Epidermal growth factor receptor	0.079
Pde8	Phosphodiesterase 8	0.078
Rac1	CG2248 gene product from transcript CG2248-RA	0.077
Akt1	CG4006 gene product from transcript CG4006-RA	0.074
Sir2	CG5216 gene product from transcript CG5216-RA	0.074
Prm	Paramyosin	0.074
Mhc	Myosin heavy chain	0.070	Zebrafish Mouse
kuz	kuzbanian	0.069
ImpL3	Ecdysone-inducible gene L3	0.067
NetB	Netrin-B	0.066
Fas2	Fasciclin 2	0.065
Mkp3	Mitogen-activated protein kinase phosphatase 3	0.062
caup	caupolican	0.061
Sra-1	specifically Rac1-associated protein 1	0.061
kis	kismet	0.059
Gug	Grunge	0.059
Gprk2	G protein-coupled receptor kinase 2	0.059
tna	tonalli	0.058
klg	klingon	0.057
robo	roundabout	0.056
CG4612	CG4612 gene product from transcript CG4612-RA	0.055
byn	brachyenteron	0.055
sbb	scribbler	0.055
Wnt4	Wnt oncogene analog 4	0.054
kel	kelch	0.053
up	upheld	0.053
mth	methuselah	0.053
GlyP	Glycogen phosphorylase	0.051
org-1	optomotor-blind-related-gene-1	0.048	Mouse
Tsc1	CG6147 gene product from transcript CG6147-RA	0.047
Neurochondrin	CG2330 gene product from transcript CG2330-RA	0.047
Gapdh2	Glyceraldehyde 3 phosphate dehydrogenase 2	0.047
Smox	Smad on X	0.046
Mekk1	CG7717 gene product from transcript CG7717-RB	0.046
Ipp	Inositol polyphosphate 1-phosphatase	0.046
aop	anterior open	0.045
nmo	nemo	0.044
Gapdh1	Glyceraldehyde 3 phosphate dehydrogenase 1	0.044
Grip	Glutamate receptor binding protein	0.043
Imp	IGF-II mRNA-binding protein	0.042
insc	inscuteable	0.042
Dat	Dopamine N acetyltransferase	0.041
otk	off-track	0.041
Nrx-1	Neurexin 1	0.041
dnc	dunce	0.040
rost	rolling stone	0.040
sing	singles bar	0.040
CkIalpha	Casein kinase Ialpha	0.040
cpb	capping protein beta	0.040
N	Notch	0.040	Human Mouse
G-salpha60A	G protein salpha 60A	0.040
Past1	Putative Achaete Scute Target 1	0.039	Mouse
prd	paired	0.039
dpp	decapentaplegic	0.039	Human Mouse
B-H1	BarH1	0.038
Pkc98E	Protein C kinase 98E	0.038
dsh	dishevelled	0.038
Tollo	CG6890 gene product from transcript CG6890-RA	0.038
Pka-C1	cAMP-dependent protein kinase 1	0.038
tim	timeless	0.038
tio	tiptop	0.037
FBX011	FBX011 ortholog	0.037
ush	u-shaped	0.036
simj	simjang	0.036
sd	scalloped	0.036
wit	wishful thinking	0.034
CG1910	CG1910 gene product from transcript CG1910-RB	0.034
Fs	Follistatin	0.034
sina	seven in absentia	0.034
CG1347	CG1347 gene product from transcript CG1347-RB	0.034
rg	rugose	0.033
east	enhanced adult sensory threshold	0.033
CG4699	CG4699 gene product from transcript CG4699-RJ	0.031
NetA	Netrin-A	0.031
scw	screw	0.030
Trxr-1	Thioredoxin reductase-1	0.030
cert	ceramide transfer protein	0.029
lqf	liquid facets	0.029
ths	thisbe	0.029
tin	tinman	0.029
toy	twin of eyeless	0.028
Cam	Calmodulin	0.028
Rheb	CG1081 gene product from transcript CG1081-RA	0.028
Btk29A	Btk family kinase at 29A	0.028
TpnC73F	Troponin C at 73F	0.027
Nek2	CG17256 gene product from transcript CG17256-RA	0.027
eya	eyes absent	0.027
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.027
Adf1	Adh transcription factor 1	0.027
Lrt	Leucine-rich tendon-specific protein	0.026
CG1021	CG1021 gene product from transcript CG1021-RE	0.026
NPFR1	neuropeptide F receptor	0.026
trus	toys are us	0.026
X11L	CG5675 gene product from transcript CG5675-RB	0.026
CG10750	CG10750 gene product from transcript CG10750-RA	0.026
GATAd	CG5034 gene product from transcript CG5034-RA	0.026
Tak1	TGF-beta activated kinase 1	0.026
LanB1	CG7123 gene product from transcript CG7123-RA	0.026
CG7536	CG7536 gene product from transcript CG7536-RB	0.026
Mnt	CG13316 gene product from transcript CG13316-RD	0.025
msn	misshapen	0.025
sev	sevenless	0.025	Fly
Ilk	Integrin linked kinase	0.025	Rat
chrb	charybde	0.025
Mpk2	CG5475 gene product from transcript CG5475-RB	0.025	Mouse
r2d2	CG7138 gene product from transcript CG7138-RB	0.025
dally	division abnormally delayed	0.024
par-1	CG8201 gene product from transcript CG8201-RA	0.024
crb	crumbs	0.024
Mob2	CG11711 gene product from transcript CG11711-RC	0.023
scny	scrawny	0.023
mwh	multiple wing hairs	0.022
jeb	jelly belly	0.022
RacGAP84C	CG2595 gene product from transcript CG2595-RA	0.022
rho-5	rhomboid-5	0.022
Snoo	Sno oncogene	0.022
CG3563	CG3563 gene product from transcript CG3563-RA	0.022
C3G	CG42328 gene product from transcript CG42328-RC	0.022
Ald	Aldolase	0.021
vimar	visceral mesodermal armadillo-repeats	0.021
dgo	diego	0.021
Clk	Clock	0.021
Dcr-2	Dicer-2	0.021
Gyc76C	Guanylyl cyclase at 76C	0.020
nvy	nervy	0.020
sens	senseless	0.020
toe	twin of eyg	0.020
CdGAPr	CG10538 gene product from transcript CG10538-RA	0.020
rtet	tetracycline resistance	0.019
Poxn	Pox neuro	0.019
spen	split ends	0.019
CG32810	CG32810 gene product from transcript CG32810-RB	0.019
Act87E	Actin 87E	0.019
comt	comatose	0.019
px	plexus	0.019
run	runt	0.019
Msp-300	Muscle-specific protein 300	0.019
tsh	teashirt	0.019
CG12985	CG12985 gene product from transcript CG12985-RA	0.019
eyg	eyegone	0.018
PGRP-SC2	CG14745 gene product from transcript CG14745-RA	0.018
CG14869	CG14869 gene product from transcript CG14869-RB	0.018
CG13131	CG13131 gene product from transcript CG13131-RB	0.018
Nca	Neurocalcin	0.018
dos	daughter of sevenless	0.018
l(2)efl	lethal (2) essential for life	0.018
sqz	squeeze	0.018
trio	CG18214 gene product from transcript CG18214-RA	0.018
slp1	sloppy paired 1	0.018
dco	discs overgrown	0.018
CG5790	CG5790 gene product from transcript CG5790-RA	0.017
Tom34	Translocase of outer membrane 34	0.017
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.017
beat-Ia	beaten path Ia	0.017
danr	distal antenna-related	0.017
btl	breathless	0.017
ac	achaete	0.017
Con	Connectin	0.017
Cdc27	CG8610 gene product from transcript CG8610-RA	0.017
inx7	innexin 7	0.017
Dap160	Dynamin associated protein 160	0.016
ft	fat	0.016
l(3)82Fd	CG32464 gene product from transcript CG32464-RR	0.016
Eip71CD	Ecdysone-induced protein 28/29kD	0.016
zip	zipper	0.016	Mouse
frc	fringe connection	0.016
CG34139	CG34139 gene product from transcript CG34139-RD	0.016
DNApol-iota	CG7602 gene product from transcript CG7602-RB	0.016
bsk	basket	0.016
Adgf-A	Adenosine deaminase-related growth factor A	0.016
amos	absent MD neurons and olfactory sensilla	0.016
JIL-1	CG6297 gene product from transcript CG6297-RA	0.015	Fly
rut	rutabaga	0.015
sxc	super sex combs	0.015
slmb	supernumerary limbs	0.015
Fim	Fimbrin	0.015
CG14044	CG14044 gene product from transcript CG14044-RA	0.015
VhaAC39	Vacuolar H[+]-ATPase C39 subunit	0.015
RhoGAP100F	CG1976 gene product from transcript CG1976-RB	0.015
abs	abstrakt	0.015
wupA	wings up A	0.015
bi	bifid	0.015	Human
H	Hairless	0.015
dome	domeless	0.015
CG32528	CG32528 gene product from transcript CG32528-RA	0.015
tipE	temperature-induced paralytic E	0.015
mura	murashka	0.015
tld	tolloid	0.015
fz	frizzled	0.015
BicD	Bicaudal D	0.014
RanBPM	Ran-binding protein M	0.014
CG12024	CG12024 gene product from transcript CG12024-RA	0.014
fj	four-jointed	0.014
TpnC47D	Troponin C at 47D	0.014
Smr	Smrter	0.014
nord	CG30418 gene product from transcript CG30418-RA	0.014
CG10252	CG10252 gene product from transcript CG10252-RA	0.014
mtt	mangetout	0.014
LanB2	Laminin B2	0.014
pll	pelle	0.014
Kr	Kruppel	0.014
Krn	Keren	0.014
Traf6	TNF-receptor-associated factor 6	0.014
Flo-2	flotillin 2	0.014
osa	CG7467 gene product from transcript CG7467-RD	0.014
dock	dreadlocks	0.014
exex	extra-extra	0.014
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.014
CG5541	CG5541 gene product from transcript CG5541-RA	0.014
loj	logjam	0.013
Syx1A	Syntaxin 1A	0.013
tomosyn	CG17762 gene product from transcript CG17762-RB	0.013
cher	cheerio	0.013
CG9650	CG9650 gene product from transcript CG9650-RG	0.013
be	ben	0.013
skf	skiff	0.013
bnl	branchless	0.013
tup	tailup	0.013
18w	18 wheeler	0.013
CG7409	CG7409 gene product from transcript CG7409-RA	0.013
pio	piopio	0.013
Dg	Dystroglycan	0.013
LanA	Laminin A	0.013
CG9297	CG9297 gene product from transcript CG9297-RB	0.013
l(2)k16918	lethal (2) k16918	0.013
robl37BC	CG15171 gene product from transcript CG15171-RA	0.012
CG6800	CG6800 gene product from transcript CG6800-RA	0.012
Rdl	Resistant to dieldrin	0.012
spz	spatzle	0.012
Nmdar1	NMDA receptor 1	0.012
Klp68D	Kinesin-like protein at 68D	0.012
bt	bent	0.012
betaInt-nu	beta[nu] integrin	0.012
stumps	CG31317 gene product from transcript CG31317-RC	0.012
CG15730	CG15730 gene product from transcript CG15730-RA	0.012
slp2	sloppy paired 2	0.012
neur	neuralized	0.012
CG6579	CG6579 gene product from transcript CG6579-RB	0.012
Gr28b	Gustatory receptor 28b	0.012
omd	oocyte maintenance defects	0.012
CG8709	CG8709 gene product from transcript CG8709-RK	0.012
beta4GalNAcTA	CG8536 gene product from transcript CG8536-RA	0.012
GABA-B-R2	metabotropic GABA-B receptor subtype 2	0.012
lz	lozenge	0.012
Eip63E	Ecdysone-induced protein 63E	0.012
CG42446	CG42446 gene product from transcript CG42446-RA	0.012
fry	furry	0.012
Atg1	Autophagy-specific gene 1	0.012
Psn	Presenilin	0.012
m6	E(spl) region transcript m6	0.012
Oamb	Octopamine receptor in mushroom bodies	0.012
Hs3st-B	Heparan sulfate 3-O sulfotransferase-B	0.011
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.011
Gdh	Glutamate dehydrogenase	0.011
dsd	distracted	0.011
Nsf2	NEM-sensitive fusion protein 2	0.011
trp	transient receptor potential	0.011
spi	spitz	0.011
ATP7	CG1886 gene product from transcript CG1886-RB	0.011
BG4	CG12297 gene product from transcript CG12297-RA	0.011
kni	knirps	0.011
Ser	Serrate	0.011
foi	fear-of-intimacy	0.011
Arf79F	ADP ribosylation factor 79F	0.011	Fly
ald	altered disjunction	0.011
Paip2	polyA-binding protein interacting protein 2	0.011
CG17322	CG17322 gene product from transcript CG17322-RB	0.011
CG2528	CG2528 gene product from transcript CG2528-RB	0.011
rho	rhomboid	0.011
CG17370	CG17370 gene product from transcript CG17370-RD	0.011
CG10641	CG10641 gene product from transcript CG10641-RA	0.011
CG3558	CG3558 gene product from transcript CG3558-RC	0.011
Taf4	TBP-associated factor 4	0.011
Wnt2	Wnt oncogene analog 2	0.011
Socs44A	Suppressor of Cytokine Signaling at 44A	0.011
disp	dispatched	0.011
Doc2	Dorsocross2	0.011
rictor	rapamycin-insensitive companion of Tor	0.011
pxb	CG33207 gene product from transcript CG33207-RB	0.011
cdc14	CG7134 gene product from transcript CG7134-RB	0.010
hh	hedgehog	0.010	Zebrafish Mouse
Gs1	Glutamine synthetase 1	0.010
ksr	kinase suppressor of ras	0.010
gkt	glaikit	0.010
CG13627	CG13627 gene product from transcript CG13627-RA	0.010
Spn27A	Serpin 27A	0.010
Pi3K68D	Phosphotidylinositol 3 kinase 68D	0.010
sktl	skittles	0.010
per	period	0.010
CG9063	CG9063 gene product from transcript CG9063-RA	0.010
mav	maverick	0.010
pex13	peroxin 13	0.010
Vhl	von Hippel-Lindau	0.010