IMP: Integrative Multi-species Prediction

Drosophila melanogaster

28 genes annotated in fly

cellular response to insulin stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to insulin stimulus"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cellular response to insulin stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.913
Ilp6	Insulin-like peptide 6	0.765
Mad	Mothers against dpp	0.753
S6k	RPS6-p70-protein kinase	0.671	Human Rat
Ilp5	Insulin-like peptide 5	0.551	Fly
sNPF-R	short neuropeptide F receptor	0.452
Ilp2	Insulin-like peptide 2	0.352
Lnk	CG17367 gene product from transcript CG17367-RC	0.329
jeb	jelly belly	0.326
sxc	super sex combs	0.299
dm	diminutive	0.244
InR	Insulin-like receptor	0.242
Sir2	CG5216 gene product from transcript CG5216-RA	0.238	Human
Rheb	CG1081 gene product from transcript CG1081-RA	0.234
Nf1	Neurofibromin 1	0.225
CG13253	CG13253 gene product from transcript CG13253-RB	0.224
Ide	Insulin degrading metalloproteinase	0.212
Pk61C	Protein kinase 61C	0.204	Human
chico	CG5686 gene product from transcript CG5686-RB	0.188
ns3	nucleostemin 3	0.180
pico	CG11940 gene product from transcript CG11940-RA	0.159
spi	spitz	0.153
skpA	CG16983 gene product from transcript CG16983-RD	0.151
Thor	CG8846 gene product from transcript CG8846-RA	0.133
egl	egalitarian	0.129
dco	discs overgrown	0.127
Ilp3	Insulin-like peptide 3	0.122	Fly
didum	dilute class unconventional myosin	0.121
if	inflated	0.121
klar	klarsicht	0.116
ppk	pickpocket	0.110
B4	CG9239 gene product from transcript CG9239-RA	0.110
scyl	scylla	0.108
Rac1	CG2248 gene product from transcript CG2248-RA	0.105
Lsd-1	Lipid storage droplet-1	0.104
Ras85D	Ras oncogene at 85D	0.098
mtt	mangetout	0.097
ash2	absent, small, or homeotic discs 2	0.087
retn	retained	0.084
melt	melted	0.080
sNPF	short neuropeptide F precursor	0.074
RanBPM	Ran-binding protein M	0.074
Tbh	Tyramine beta hydroxylase	0.070
CG13890	CG13890 gene product from transcript CG13890-RA	0.067
Hem	HEM-protein	0.065
Tsp	Thrombospondin	0.063
Akt1	CG4006 gene product from transcript CG4006-RA	0.061
path	pathetic	0.060
Octbeta2R	CG33976 gene product from transcript CG33976-RA	0.056	Rat
Fatp	Fatty acid (long chain) transport protein	0.056
CG11284	CG11284 gene product from transcript CG11284-RA	0.055
CG11486	CG11486 gene product from transcript CG11486-RG	0.055
BHD	Birt-Hogg-Dube homolog	0.054
dib	disembodied	0.050
ImpL2	Ecdysone-inducible gene L2	0.050
CycG	Cyclin G	0.050
dock	dreadlocks	0.049
Clk	Clock	0.049
Ork1	Open rectifier K[+] channel 1	0.048
Bre1	CG10542 gene product from transcript CG10542-RA	0.047
CG42629	CG42629 gene product from transcript CG42629-RB	0.046
step	steppke	0.046
p53	CG33336 gene product from transcript CG33336-RB	0.044
Pdp1	PAR-domain protein 1	0.043
MED24	Mediator complex subunit 24	0.043
put	punt	0.043
Sin3A	CG8815 gene product from transcript CG8815-RC	0.043
Cdc42	CG12530 gene product from transcript CG12530-RA	0.042
neuroligin	CG13772 gene product from transcript CG13772-RA	0.042
Atg1	Autophagy-specific gene 1	0.041
CG14937	CG14937 gene product from transcript CG14937-RA	0.040
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.039
NFAT	NFAT homolog	0.038
Trxr-1	Thioredoxin reductase-1	0.037
boss	bride of sevenless	0.037
HLH106	Helix loop helix protein 106	0.036
fra	frazzled	0.035
CG33138	CG33138 gene product from transcript CG33138-RA	0.035
CdsA	CDP diglyceride synthetase	0.035
MTF-1	Metal response element-binding Transcription Factor-1	0.034
Rack1	Receptor of activated protein kinase C 1	0.034
Tor	Target of rapamycin	0.033
Rdl	Resistant to dieldrin	0.033
trio	CG18214 gene product from transcript CG18214-RA	0.032
Gsc	Goosecoid	0.031
rictor	rapamycin-insensitive companion of Tor	0.031
Ptth	Prothoracicotropic hormone	0.031
Indy	I'm not dead yet	0.030
unk	unkempt	0.030
klg	klingon	0.030
Cyp6t3	CG8457 gene product from transcript CG8457-RA	0.029
Oamb	Octopamine receptor in mushroom bodies	0.029
Gyc76C	Guanylyl cyclase at 76C	0.029
Spargel	CG9809 gene product from transcript CG9809-RB	0.029
Mnt	CG13316 gene product from transcript CG13316-RD	0.028
kis	kismet	0.028
Vha68-1	CG12403 gene product from transcript CG12403-RA	0.028
shg	shotgun	0.028
Gycalpha99B	Guanylyl cyclase alpha-subunit at 99B	0.028
cutlet	CG33122 gene product from transcript CG33122-RA	0.027
foxo	forkhead box, sub-group O	0.027
Glut1	Glucose transporter 1	0.027
CycD	Cyclin D	0.027	Rat
Atg8a	Autophagy-specific gene 8a	0.027
CG7158	CG7158 gene product from transcript CG7158-RA	0.026
Dsk	Drosulfakinin	0.026
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.026
pasha	partner of drosha	0.026
Hdac3	Histone deacetylase 3	0.026
hth	homothorax	0.026
rpr	reaper	0.026
CG14869	CG14869 gene product from transcript CG14869-RB	0.026
CG11055	CG11055 gene product from transcript CG11055-RB	0.025
blw	bellwether	0.025
CG8090	CG8090 gene product from transcript CG8090-RB	0.025
Taf4	TBP-associated factor 4	0.025
dac	dachshund	0.025
sev	sevenless	0.024	Fly
sbr	small bristles	0.024
Myo31DF	Myosin 31DF	0.024
CG3308	CG3308 gene product from transcript CG3308-RA	0.024
skap	skpA associated protein	0.024
Ilp4	Insulin-like peptide 4	0.024	Fly
Hcf	Host cell factor	0.023
babo	baboon	0.023
S6kII	RPS6-protein kinase-II	0.023
CG6800	CG6800 gene product from transcript CG6800-RA	0.023
Dad	Daughters against dpp	0.022
CG14805	CG14805 gene product from transcript CG14805-RA	0.022
east	enhanced adult sensory threshold	0.022
CG3847	CG3847 gene product from transcript CG3847-RA	0.022
Oatp74D	Organic anion transporting polypeptide 74D	0.022
Lis-1	Lissencephaly-1	0.022
AcCoAS	Acetyl Coenzyme A synthase	0.021
tud	tudor	0.021
ort	ora transientless	0.021
frj	farjavit	0.021
trp	transient receptor potential	0.020
CG31352	CG31352 gene product from transcript CG31352-RA	0.020
ImpL3	Ecdysone-inducible gene L3	0.020
Tequila	CG4821 gene product from transcript CG4821-RE	0.020
wbl	windbeutel	0.020
Su(dx)	Suppressor of deltex	0.020
sav	salvador	0.020
Pcmt	Protein-L-isoaspartate (D-aspartate) O-methyltransferase	0.020
rols	rolling pebbles	0.020
tai	taiman	0.019
Thd1	CG1981 gene product from transcript CG1981-RA	0.019
ninaA	neither inactivation nor afterpotential A	0.019
CG17082	CG17082 gene product from transcript CG17082-RD	0.019
fd85E	forkhead domain 85E	0.019
CG4289	CG4289 gene product from transcript CG4289-RA	0.019
CG9316	CG9316 gene product from transcript CG9316-RA	0.019
insc	inscuteable	0.019
byn	brachyenteron	0.019
CG5746	CG5746 gene product from transcript CG5746-RB	0.018
dnc	dunce	0.018
drk	downstream of receptor kinase	0.018	Human
Dsor1	Downstream of raf1	0.018
Pez	CG9493 gene product from transcript CG9493-RA	0.018
Pgi	Phosphoglucose isomerase	0.018
pip	pipe	0.017
eIF4G	eukaryotic translation initiation factor 4G	0.017
slik	Sterile20-like kinase	0.017
robl	roadblock	0.017
Pten	CG5671 gene product from transcript CG5671-RB	0.017
wls	wntless	0.017
CG8486	CG8486 gene product from transcript CG8486-RE	0.016
Gclc	Glutamate-cysteine ligase catalytic subunit	0.016
kst	karst	0.016
dve	defective proventriculus	0.016
Wnk	CG7177 gene product from transcript CG7177-RA	0.016
CCKLR-17D1	CCK-like receptor at 17D1	0.016
katanin-60	katanin 60	0.016
CG18135	CG18135 gene product from transcript CG18135-RC	0.016
PIP5K59B	CG3682 gene product from transcript CG3682-RE	0.016
Rala	Ras-related protein	0.016
CG3164	CG3164 gene product from transcript CG3164-RA	0.016
Hr96	Hormone receptor-like in 96	0.016
rl	rolled	0.015
Gapdh1	Glyceraldehyde 3 phosphate dehydrogenase 1	0.015
Lerp	lysosomal enzyme receptor protein	0.015
EDTP	Egg-derived tyrosine phosphatase	0.015
cdi	center divider	0.015
Pph13	PvuII-PstI homology 13	0.015
Pcaf	CG4107 gene product from transcript CG4107-RA	0.015	Human
Cam	Calmodulin	0.015
Marf	Mitochondrial assembly regulatory factor	0.015
Tpi	Triose phosphate isomerase	0.015
obst-A	obstructor-A	0.015
crq	croquemort	0.015
bsk	basket	0.015
Ptp10D	Protein tyrosine phosphatase 10D	0.015
Pi3K59F	Phosphotidylinositol 3 kinase 59F	0.015
mbc	myoblast city	0.015
CG4617	CG4617 gene product from transcript CG4617-RA	0.015
nct	nicastrin	0.015
CG14375	CG14375 gene product from transcript CG14375-RA	0.015
CkIIbeta	Casein kinase II beta subunit	0.014
rap	retina aberrant in pattern	0.014
cnk	connector enhancer of ksr	0.014
CG8677	CG8677 gene product from transcript CG8677-RA	0.014
Edem2	CG5682 gene product from transcript CG5682-RA	0.014
ftz-f1	ftz transcription factor 1	0.014
Vps35	Vacuolar protein sorting 35	0.014
alpha-Man-I	alpha Mannosidase I	0.014
pita	CG3941 gene product from transcript CG3941-RA	0.014
Ppat-Dpck	Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase	0.014
Pp2B-14D	Protein phosphatase 2B at 14D	0.014
CG12703	CG12703 gene product from transcript CG12703-RA	0.014
cher	cheerio	0.014
CG3590	CG3590 gene product from transcript CG3590-RA	0.014
t	tan	0.014
CG42630	CG42630 gene product from transcript CG42630-RA	0.014
CG8709	CG8709 gene product from transcript CG8709-RK	0.014
CG8451	CG8451 gene product from transcript CG8451-RA	0.014
Mob2	CG11711 gene product from transcript CG11711-RC	0.013
ttm50	tiny tim 50	0.013
vtd	verthandi	0.013
CadN	Cadherin-N	0.013
nonA	no on or off transient A	0.013
CG9904	CG9904 gene product from transcript CG9904-RA	0.013
CG9577	CG9577 gene product from transcript CG9577-RA	0.013
Prosap	CG30483 gene product from transcript CG30483-RA	0.013
cbs	centrosomin's beautiful sister	0.013
CG14815	CG14815 gene product from transcript CG14815-RA	0.013
gig	gigas	0.013
l(3)04053	lethal (3) 04053	0.013
slow	slowdown	0.013
Ets97D	Ets at 97D	0.013
Atf6	CG3136 gene product from transcript CG3136-RA	0.013
Invadolysin	CG3953 gene product from transcript CG3953-RA	0.013
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.013
CG1607	CG1607 gene product from transcript CG1607-RA	0.013
AdoR	Adenosine receptor	0.013
Exp6	Exportin 6	0.013
swm	second mitotic wave missing	0.013
Men	Malic enzyme	0.013
rhea	CG6831 gene product from transcript CG6831-RA	0.012
olf186-F	CG11430 gene product from transcript CG11430-RB	0.012
Ilp7	Insulin-like peptide 7	0.012
bowl	brother of odd with entrails limited	0.012
Sln	Silnoon	0.012
RN-tre	tre oncogene-related protein	0.012
CG4901	CG4901 gene product from transcript CG4901-RA	0.012
Irk3	Inwardly rectifying potassium channel 3	0.012
EndoGI	Endonuclease G inhibitor	0.012
pUf68	poly U binding factor 68kD	0.012
slif	slimfast	0.012
CG12229	CG12229 gene product from transcript CG12229-RA	0.012
Lsd-2	Lipid storage droplet-2	0.012
CycJ	Cyclin J	0.012
Cdk4	Cyclin-dependent kinase 4	0.012
htl	heartless	0.012
msn	misshapen	0.012
Kap3	Kinesin associated protein 3	0.012
CG14059	CG14059 gene product from transcript CG14059-RB	0.012
pkaap	CG4132 gene product from transcript CG4132-RA	0.012
CG6439	CG6439 gene product from transcript CG6439-RA	0.012
ERR	estrogen-related receptor	0.012
Saf-B	Scaffold attachment factor B	0.012
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.012
CG4998	CG4998 gene product from transcript CG4998-RB	0.012
CG11900	CG11900 gene product from transcript CG11900-RA	0.012
Est-P	Esterase P	0.012
CG32486	CG32486 gene product from transcript CG32486-RD	0.011
Cpr	Cytochrome P450 reductase	0.011
CG6838	CG6838 gene product from transcript CG6838-RC	0.011
Patr-1	Protein associated with topo II related - 1	0.011
CG7998	CG7998 gene product from transcript CG7998-RA	0.011
mus205	mutagen-sensitive 205	0.011
jagn	jagunal	0.011
enok	enoki mushroom	0.011
brp	bruchpilot	0.011
CG4221	CG4221 gene product from transcript CG4221-RA	0.011
Mef2	Myocyte enhancer factor 2	0.011
Ilk	Integrin linked kinase	0.011
Z600	CG17962 gene product from transcript CG17962-RA	0.011
ird1	immune response deficient 1	0.011
Pkn	Protein kinase related to protein kinase N	0.011
CG34168	CG34168 gene product from transcript CG34168-RA	0.011
fkh	fork head	0.011
CG3837	CG3837 gene product from transcript CG3837-RA	0.011
krz	kurtz	0.011
IFa	IFamide	0.011
Pde1c	Phosphodiesterase 1c	0.011
CG10083	CG10083 gene product from transcript CG10083-RA	0.011
fh	frataxin homolog	0.011
RpS25	Ribosomal protein S25	0.011
btsz	bitesize	0.011
Acer	Angiotensin-converting enzyme-related	0.011
Ten-a	Tenascin accessory	0.011
Grx-1	CG7975 gene product from transcript CG7975-RA	0.011
Trim9	CG31721 gene product from transcript CG31721-RB	0.011
ssh	slingshot	0.011
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.011
Pka-R1	cAMP-dependent protein kinase R1	0.011
not	non-stop	0.011
CG31999	CG31999 gene product from transcript CG31999-RA	0.011
CG5261	CG5261 gene product from transcript CG5261-RB	0.011
CG18754	CG18754 gene product from transcript CG18754-RB	0.011
ple	pale	0.010
atl	atlastin	0.010
GLaz	Glial Lazarillo	0.010
CG8443	CG8443 gene product from transcript CG8443-RA	0.010
LanB2	Laminin B2	0.010
Dscam	Down syndrome cell adhesion molecule	0.010
Zw	Zwischenferment	0.010
CG9541	CG9541 gene product from transcript CG9541-RA	0.010
rho	rhomboid	0.010
Hus1-like	CG2525 gene product from transcript CG2525-RA	0.010
ssp4	short spindle 4	0.010
Coq2	Coenzyme Q biosynthesis protein 2	0.010
CG5840	CG5840 gene product from transcript CG5840-RB	0.010
sqd	squid	0.010
Task6	CG9637 gene product from transcript CG9637-RC	0.010
p130CAS	CG1212 gene product from transcript CG1212-RA	0.010	Rat