IMP: Integrative Multi-species Prediction

Drosophila melanogaster

21 genes annotated in fly

Multi-species View

lamellipodium assembly

GO:0030032

Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in flyInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lamellipodium assembly"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "lamellipodium assembly" (in gray)

Name	Description	Probability	Func Analog Organism
Rac1	CG2248 gene product from transcript CG2248-RA	0.522
mbc	myoblast city	0.515
Hem	HEM-protein	0.513	Mouse
Rho1	CG8416 gene product from transcript CG8416-RB	0.504
Ephrin	CG1862 gene product from transcript CG1862-RA	0.416
Sra-1	specifically Rac1-associated protein 1	0.384	Mouse
robo	roundabout	0.372	Zebrafish
cpb	capping protein beta	0.343
da	daughterless	0.326
chic	chickadee	0.325
Arp66B	Actin-related protein 66B	0.313
ena	enabled	0.309
Vrp1	Verprolin 1	0.283
Rac2	CG8556 gene product from transcript CG8556-RA	0.184
par-1	CG8201 gene product from transcript CG8201-RA	0.181
S6k	RPS6-p70-protein kinase	0.158
Sop2	Suppressor of profilin 2	0.151
Arp14D	Actin-related protein 14D	0.119
RanBPM	Ran-binding protein M	0.089
Dlic	Dynein light intermediate chain	0.088
Abl	Abl tyrosine kinase	0.079
Arc-p34	CG10954 gene product from transcript CG10954-RA	0.077	Human
Mrtf	Myocardin-related transcription factor	0.073
cta	concertina	0.068
Pak3	CG14895 gene product from transcript CG14895-RA	0.066
numb	CG3779 gene product from transcript CG3779-RB	0.057
Src64B	Src oncogene at 64B	0.054
baz	bazooka	0.053
l(2)k16918	lethal (2) k16918	0.052
wb	wing blister	0.051
twi	twist	0.050
Dcr-1	Dicer-1	0.049
Myo31DF	Myosin 31DF	0.048
Abi	Abelson interacting protein	0.047
twf	twinfilin	0.045
zfh1	Zn finger homeodomain 1	0.044
BicD	Bicaudal D	0.043
Rpn6	Proteasome p44.5 subunit	0.041
Rala	Ras-related protein	0.040
mid	midline	0.040
mats	mob as tumor suppressor	0.040
lqfR	liquid facets-Related	0.038
comm	commissureless	0.037
sim	single-minded	0.036
Dscam	Down syndrome cell adhesion molecule	0.035
CG17082	CG17082 gene product from transcript CG17082-RD	0.033
kon	kon-tiki	0.032
bsk	basket	0.032
flr	flare	0.032
cpa	capping protein alpha	0.032
Chc	Clathrin heavy chain	0.031
Ilk	Integrin linked kinase	0.031
Six4	CG3871 gene product from transcript CG3871-RA	0.030
FucT6	alpha1,6-fucosyltransferase	0.030
CG14869	CG14869 gene product from transcript CG14869-RB	0.030
tai	taiman	0.029
sli	slit	0.029	Human
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.028
kuz	kuzbanian	0.028
pll	pelle	0.028
pod1	CG4532 gene product from transcript CG4532-RF	0.028
RhoGEF2	CG9635 gene product from transcript CG9635-RF	0.027
otk	off-track	0.027
LamC	Lamin C	0.027
Gyc76C	Guanylyl cyclase at 76C	0.026
trio	CG18214 gene product from transcript CG18214-RA	0.026
p120ctn	Adherens junction protein p120	0.026
Wnt5	Wnt oncogene analog 5	0.025
exba	extra bases	0.025
RhoGAPp190	CG32555 gene product from transcript CG32555-RB	0.024
Cortactin	CG3637 gene product from transcript CG3637-RA	0.024
msn	misshapen	0.024
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.024
CG3563	CG3563 gene product from transcript CG3563-RA	0.023
hkb	huckebein	0.023
lace	CG4162 gene product from transcript CG4162-RA	0.023
btl	breathless	0.023
in	inturned	0.023
Pros25	Proteasome 25kD subunit	0.022
Cdc42	CG12530 gene product from transcript CG12530-RA	0.022
tup	tailup	0.022
bin	biniou	0.021
lea	leak	0.020	Zebrafish
Arf51F	ADP ribosylation factor 51F	0.020
Pkc98E	Protein C kinase 98E	0.020
HSPC300	CG30173 gene product from transcript CG30173-RA	0.020
fz	frizzled	0.019
Lim3	CG10699 gene product from transcript CG10699-RB	0.019
blow	blown fuse	0.019
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.018
rols	rolling pebbles	0.018
CG11791	CG11791 gene product from transcript CG11791-RB	0.018
hd	humpty dumpty	0.017
zip	zipper	0.017
beta-Spec	beta Spectrin	0.016
spo	spook	0.016
kel	kelch	0.015
kni	knirps	0.015
Pak	PAK-kinase	0.015
Tl	Toll	0.015
pcx	pecanex	0.015
Gef26	CG9491 gene product from transcript CG9491-RB	0.015
Eps-15	Epidermal growth factor receptor pathway substrate clone 15	0.014
ric8a	CG15797 gene product from transcript CG15797-RA	0.014
EndoGI	Endonuclease G inhibitor	0.014
Flo-2	flotillin 2	0.014
vir	virilizer	0.014
chinmo	Chronologically inappropriate morphogenesis	0.014
Akt1	CG4006 gene product from transcript CG4006-RA	0.014
byn	brachyenteron	0.014
siz	schizo	0.014
sina	seven in absentia	0.013
Pvf1	PDGF- and VEGF-related factor 1	0.013
tin	tinman	0.013
Ten-m	Tenascin major	0.013
LanB2	Laminin B2	0.013
sn	singed	0.013
Fas3	Fasciclin 3	0.013
vav	CG7893 gene product from transcript CG7893-RB	0.013	Mouse
betaggt-I	beta subunit of type I geranylgeranyl transferase	0.013
CG9053	CG9053 gene product from transcript CG9053-RA	0.013
CG3573	CG3573 gene product from transcript CG3573-RA	0.013
Sbf	SET domain binding factor	0.013
Tsp68C	Tetraspanin 68C	0.013
slp2	sloppy paired 2	0.012
ird1	immune response deficient 1	0.012
nimC3	nimrod C3	0.012
CG12029	CG12029 gene product from transcript CG12029-RB	0.012
Mp20	Muscle protein 20	0.012
Traf6	TNF-receptor-associated factor 6	0.012
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.012
CrebA	Cyclic-AMP response element binding protein A	0.012
Mad	Mothers against dpp	0.012
Baldspot	CG3971 gene product from transcript CG3971-RA	0.012
Trxr-1	Thioredoxin reductase-1	0.012
Khc	Kinesin heavy chain	0.012
InR	Insulin-like receptor	0.012
nullo	CG14426 gene product from transcript CG14426-RB	0.012
Drp1	Dynamin related protein 1	0.012
bnl	branchless	0.012
erm	earmuff	0.012
Mpk2	CG5475 gene product from transcript CG5475-RB	0.012
gcm	glial cells missing	0.012
Crag	Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein	0.011
RhoGAP92B	CG4755 gene product from transcript CG4755-RA	0.011
SoxN	SoxNeuro	0.011
WASp	CG1520 gene product from transcript CG1520-RA	0.011
Rme-8	Receptor mediated endocytosis 8	0.011
Uba1	Ubiquitin activating enzyme 1	0.011
ey	eyeless	0.011
Syx1A	Syntaxin 1A	0.011
snk	snake	0.011
lqf	liquid facets	0.011
sol	small optic lobes	0.011
NetA	Netrin-A	0.011
ImpL3	Ecdysone-inducible gene L3	0.011
ems	empty spiracles	0.010
pon	partner of numb	0.010
pyr	pyramus	0.010
dia	diaphanous	0.010
pfk	piefke	0.010
cindr	CIN85 and CD2AP orthologue	0.010