IMP: Integrative Multi-species Prediction

Drosophila melanogaster

19 genes annotated in fly

g2 m transition of mitotic cell cycle

The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "g2 m transition of mitotic cell cycle"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "g2 m transition of mitotic cell cycle" (in gray)

Name	Description	Probability	Func Analog Organism
Taf4	TBP-associated factor 4	0.302
orb	oo18 RNA-binding protein	0.226
DNApol-alpha60	DNA polymerase alpha 60kD	0.164
spn-B	spindle B	0.132
CycE	Cyclin E	0.122
pUf68	poly U binding factor 68kD	0.111
MCPH1	Microcephalin	0.109
mus304	mutagen-sensitive 304	0.105
CycB3	Cyclin B3	0.100	Yeast
mei-41	meiotic 41	0.088
ncd	non-claret disjunctional	0.076
dup	double parked	0.073
dpa	disc proliferation abnormal	0.073
fzy	fizzy	0.070
spn-A	spindle A	0.070
CycB	Cyclin B	0.065	Yeast
nej	nejire	0.064
Klp3A	Kinesin-like protein at 3A	0.063
pie	pineapple eye	0.062
Nup154	Nucleoporin 154	0.060
Cdk4	Cyclin-dependent kinase 4	0.060	Human
mei-9	meiotic 9	0.058
CG11071	CG11071 gene product from transcript CG11071-RA	0.058
CG9772	CG9772 gene product from transcript CG9772-RB	0.058
geminin	CG3183 gene product from transcript CG3183-RA	0.054
Pngl	PNGase-like	0.053
CycG	Cyclin G	0.053
ftz-f1	ftz transcription factor 1	0.050
mus301	mutagen-sensitive 301	0.047
mars	CG17064 gene product from transcript CG17064-RB	0.046
lok	loki	0.046	Human
rux	roughex	0.045
Su(H)	Suppressor of Hairless	0.043
dap	dacapo	0.042
Rbf	Retinoblastoma-family protein	0.041
mus309	mutagen-sensitive 309	0.040
mi	minus	0.039
p53	CG33336 gene product from transcript CG33336-RB	0.037
CycD	Cyclin D	0.036	Human
Cul-5	Cullin-5	0.036
Grip71	CG10346 gene product from transcript CG10346-RA	0.034
Brca2	Breast cancer 2, early onset homolog	0.032
BubR1	Bub1-related kinase	0.030
Cap-G	CG34438 gene product from transcript CG34438-RF	0.028
png	pan gu	0.028
pim	pimples	0.028
yki	yorkie	0.028
cmet	CENP-meta	0.027
Akt1	CG4006 gene product from transcript CG4006-RA	0.027
Rala	Ras-related protein	0.027
wee	CG4488 gene product from transcript CG4488-RA	0.027
barr	barren	0.026
plu	plutonium	0.026
zuc	zucchini	0.025
CG4680	CG4680 gene product from transcript CG4680-RA	0.025
jub	Ajuba LIM protein	0.024
Xpd	Xeroderma pigmentosum D	0.024
Klp10A	CG1453 gene product from transcript CG1453-RA	0.023
RecQ4	CG7487 gene product from transcript CG7487-RA	0.023
CycJ	Cyclin J	0.022
Myt1	CG32417 gene product from transcript CG32417-RA	0.021
Tak1	TGF-beta activated kinase 1	0.021
dco	discs overgrown	0.021
Cdc27	CG8610 gene product from transcript CG8610-RA	0.020
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.019
4EHP	CG33100 gene product from transcript CG33100-RA	0.019
Cks85A	Cyclin-dependent kinase subunit 85A	0.019
l(2)gl	lethal (2) giant larvae	0.019
E(z)	Enhancer of zeste	0.018
CG6191	CG6191 gene product from transcript CG6191-RA	0.017
path	pathetic	0.017
east	enhanced adult sensory threshold	0.017
ranshi	CG9793 gene product from transcript CG9793-RA	0.017
crc	cryptocephal	0.017
Caf1-180	CG12109 gene product from transcript CG12109-RB	0.017
timeout	CG7855 gene product from transcript CG7855-RA	0.016
lid	little imaginal discs	0.016
dah	discontinuous actin hexagon	0.016
Syx13	Syntaxin 13	0.016
abs	abstrakt	0.016
Lnk	CG17367 gene product from transcript CG17367-RC	0.015
swa	swallow	0.015
ns2	nucleostemin 2	0.015
mus101	mutagen-sensitive 101	0.015
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.015
bin3	bicoid-interacting protein 3	0.015
rept	reptin	0.014
c(3)G	crossover suppressor on 3 of Gowen	0.014
dlt	discs lost	0.014
Cks30A	Cyclin-dependent kinase subunit 30A	0.014
fs(1)M3	female sterile (1) M3	0.014
CG42709	CG42709 gene product from transcript CG42709-RC	0.014
grh	grainy head	0.014
flower	CG6151 gene product from transcript CG6151-RA	0.014
CG12734	CG12734 gene product from transcript CG12734-RA	0.014
polybromo	CG11375 gene product from transcript CG11375-RA	0.013
chico	CG5686 gene product from transcript CG5686-RB	0.013
Nek2	CG17256 gene product from transcript CG17256-RA	0.013
nod	no distributive disjunction	0.013
adp	adipose	0.013
trbl	tribbles	0.013
Coq2	Coenzyme Q biosynthesis protein 2	0.013
Df31	Decondensation factor 31	0.012
lute	CG5319 gene product from transcript CG5319-RA	0.012
baz	bazooka	0.012
Grip84	gamma-tubulin ring protein 84	0.012
hd	humpty dumpty	0.012
polo	CG12306 gene product from transcript CG12306-RA	0.012	Human
rad50	CG6339 gene product from transcript CG6339-RD	0.012
caz	cabeza	0.012
foxo	forkhead box, sub-group O	0.011
Tis11	Tis11 homolog	0.011
cnn	centrosomin	0.011
slam	slow as molasses	0.011
tefu	telomere fusion	0.011	Human Zebrafish
Gga	CG3002 gene product from transcript CG3002-RB	0.011
Ptp61F	Protein tyrosine phosphatase 61F	0.011
Tip60	CG6121 gene product from transcript CG6121-RA	0.011
calypso	CG8445 gene product from transcript CG8445-RB	0.011
lolal	lola like	0.010
wisp	wispy	0.010
CG6066	CG6066 gene product from transcript CG6066-RA	0.010
Pez	CG9493 gene product from transcript CG9493-RA	0.010
heph	hephaestus	0.010
Mcm10	Sensitized chromosome inheritance modifier 19	0.010
Sse	Separase	0.010
tna	tonalli	0.010