IMP: Integrative Multi-species Prediction

Drosophila melanogaster

31 genes annotated in fly

g1 s transition of mitotic cell cycle

The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "g1 s transition of mitotic cell cycle"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "g1 s transition of mitotic cell cycle" (in gray)

Name	Description	Probability	Func Analog Organism
Rbf	Retinoblastoma-family protein	0.929
Ras85D	Ras oncogene at 85D	0.746
dap	dacapo	0.674
Akt1	CG4006 gene product from transcript CG4006-RA	0.597	Human
shn	schnurri	0.433
Mad	Mothers against dpp	0.369
gig	gigas	0.349
Pten	CG5671 gene product from transcript CG5671-RB	0.307	Human
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.295
Pk61C	Protein kinase 61C	0.263
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.247
phl	pole hole	0.231
cdc2c	CG10498 gene product from transcript CG10498-RC	0.218	Mouse Fly
Dp	DP transcription factor	0.210
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.187
EcR	Ecdysone receptor	0.187
tkv	thickveins	0.178
osa	CG7467 gene product from transcript CG7467-RD	0.167
yki	yorkie	0.160
heph	hephaestus	0.157
Myd88	CG2078 gene product from transcript CG2078-RA	0.155
CycA	Cyclin A	0.124
ci	cubitus interruptus	0.119
Cdk4	Cyclin-dependent kinase 4	0.115	Human Worm
rap	retina aberrant in pattern	0.106
CSN8	COP9 complex homolog subunit 8	0.093
Pabp2	CG2163 gene product from transcript CG2163-RA	0.089
RASSF8	CG5053 gene product from transcript CG5053-RA	0.085
Rab11	Rab-protein 11	0.084
hep	hemipterous	0.083
CycB	Cyclin B	0.080	Yeast
dm	diminutive	0.080
Mer	Merlin	0.079
bel	belle	0.075	Human
kay	kayak	0.075
jub	Ajuba LIM protein	0.073
spen	split ends	0.069
Tao-1	CG14217 gene product from transcript CG14217-RF	0.065
MED6	Mediator complex subunit 6	0.062
l(1)dd4	lethal (1) discs degenerate 4	0.061
p53	CG33336 gene product from transcript CG33336-RB	0.060	Human Mouse
RecQ4	CG7487 gene product from transcript CG7487-RA	0.059
caz	cabeza	0.056
Smr	Smrter	0.056
cnk	connector enhancer of ksr	0.052
Tsc1	CG6147 gene product from transcript CG6147-RA	0.052
mip120	Myb-interacting protein 120	0.051
myoglianin	CG1838 gene product from transcript CG1838-RD	0.050
HmgD	High mobility group protein D	0.050
Med	Medea	0.049	Fly
Psf2	CG18013 gene product from transcript CG18013-RA	0.049
Map60	Microtubule-associated protein 60	0.049
CG9339	CG9339 gene product from transcript CG9339-RG	0.049
gek	genghis khan	0.048
CycD	Cyclin D	0.048	Human Mouse Rat
brm	brahma	0.047
MED17	Mediator complex subunit 17	0.047
Rm62	CG10279 gene product from transcript CG10279-RD	0.045
Mes2	CG11100 gene product from transcript CG11100-RB	0.044
CycG	Cyclin G	0.043
imd	immune deficiency	0.043
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.043
Atf6	CG3136 gene product from transcript CG3136-RA	0.042
SAK	Sak kinase	0.042
sd	scalloped	0.042
wdb	widerborst	0.041
CycE	Cyclin E	0.041
pie	pineapple eye	0.041
emb	embargoed	0.040
skd	skuld	0.040
kto	kohtalo	0.040
gbb	glass bottom boat	0.039
Sfmbt	Scm-related gene containing four mbt domains	0.039
Rac1	CG2248 gene product from transcript CG2248-RA	0.039
Fs(2)Ket	Female sterile (2) Ketel	0.039
pan	pangolin	0.039
fdl	fused lobes	0.039
CG4400	CG4400 gene product from transcript CG4400-RA	0.038
asf1	anti-silencing factor 1	0.038
CG9772	CG9772 gene product from transcript CG9772-RB	0.038
hpo	hippo	0.036
growl	CG14648 gene product from transcript CG14648-RA	0.035
Pc	Polycomb	0.035
Cbl	CG7037 gene product from transcript CG7037-RB	0.034
Mcm3	Minichromosome maintenance 3	0.034
brat	brain tumor	0.034
CtBP	C-terminal Binding Protein	0.034
Tor	Target of rapamycin	0.034
simj	simjang	0.033
cdc2	CG5363 gene product from transcript CG5363-RA	0.033
eIF4AIII	CG7483 gene product from transcript CG7483-RA	0.033
MED26	Mediator complex subunit 26	0.033
pic	piccolo	0.033
RnrL	Ribonucleoside diphosphate reductase large subunit	0.032
emc	extra macrochaetae	0.032	Human Mouse
e(y)3	enhancer of yellow 3	0.032
Snoo	Sno oncogene	0.031
cdm	cadmus	0.031
ago	archipelago	0.031
mad2	CG17498 gene product from transcript CG17498-RA	0.031
Crag	Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein	0.030
Ipp	Inositol polyphosphate 1-phosphatase	0.030
stg	string	0.030
CG4785	CG4785 gene product from transcript CG4785-RA	0.030
polybromo	CG11375 gene product from transcript CG11375-RA	0.029
JhI-1	Juvenile hormone-inducible protein 1	0.029
Bx42	CG8264 gene product from transcript CG8264-RA	0.029
gro	groucho	0.029
GATAd	CG5034 gene product from transcript CG5034-RA	0.029
HLH54F	CG5005 gene product from transcript CG5005-RA	0.028
RfC3	Replication factor C subunit 3	0.028
RnrS	Ribonucleoside diphosphate reductase small subunit	0.028
Caf1-180	CG12109 gene product from transcript CG12109-RB	0.027
SmE	Small ribonucleoprotein particle protein SmE	0.027
for	foraging	0.027
pAbp	polyA-binding protein	0.026
CG14614	CG14614 gene product from transcript CG14614-RA	0.026
gfA	giant fibre A	0.026
CG32810	CG32810 gene product from transcript CG32810-RB	0.026
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.025	Human
sina	seven in absentia	0.025
wts	warts	0.025
Mcm2	Minichromosome maintenance 2	0.025
CG4747	CG4747 gene product from transcript CG4747-RB	0.024
RpII215	RNA polymerase II 215kD subunit	0.024
Atu	Another transcription unit	0.024
CG3038	CG3038 gene product from transcript CG3038-RB	0.024
mnb	minibrain	0.024
dod	dodo	0.024
sno	strawberry notch	0.023
CG13373	CG13373 gene product from transcript CG13373-RB	0.023
kn	knot	0.023
Psf3	CG2222 gene product from transcript CG2222-RA	0.023
nej	nejire	0.023
BRWD3	CG31132 gene product from transcript CG31132-RA	0.023
dwg	deformed wings	0.023
Slip1	CG1783 gene product from transcript CG1783-RA	0.023
Pur-alpha	Purine-rich binding protein-alpha	0.023
Taf8	TBP-associated factor 8	0.022
tou	toutatis	0.022
CG7544	CG7544 gene product from transcript CG7544-RA	0.022
CG2924	CG2924 gene product from transcript CG2924-RA	0.022
Su(z)12	CG8013 gene product from transcript CG8013-RA	0.022
CG9135	CG9135 gene product from transcript CG9135-RB	0.022
S6k	RPS6-p70-protein kinase	0.022	Human
esc	extra sexcombs	0.021
WRNexo	WRN exonuclease	0.021
Sse	Separase	0.021
geminin	CG3183 gene product from transcript CG3183-RA	0.021
Orc4	Origin recognition complex subunit 4	0.021
wnd	wallenda	0.021
dally	division abnormally delayed	0.021
FBX011	FBX011 ortholog	0.021
CG3508	CG3508 gene product from transcript CG3508-RB	0.021
smt3	CG4494 gene product from transcript CG4494-RA	0.021
RfC38	Replication factor C 38kD subunit	0.021
InR	Insulin-like receptor	0.020
His4r	Histone H4 replacement	0.020
bun	bunched	0.020
CG5746	CG5746 gene product from transcript CG5746-RB	0.020
bchs	blue cheese	0.020
Scm	Sex comb on midleg	0.020
rno	rhinoceros	0.020	Human
Rel	Relish	0.020
mus205	mutagen-sensitive 205	0.020
X11L	CG5675 gene product from transcript CG5675-RB	0.019
kon	kon-tiki	0.019
lin	lines	0.019
fzy	fizzy	0.019
CG14057	CG14057 gene product from transcript CG14057-RA	0.019
Caf1-105	CG12892 gene product from transcript CG12892-RA	0.019
MED16	Mediator complex subunit 16	0.019
Cks30A	Cyclin-dependent kinase subunit 30A	0.019
dmt	dalmatian	0.018
CkIalpha	Casein kinase Ialpha	0.018
ik2	IkappaB kinase-like 2	0.018
plu	plutonium	0.018
CG7033	CG7033 gene product from transcript CG7033-RC	0.018
Mnt	CG13316 gene product from transcript CG13316-RD	0.018
cort	cortex	0.018
Pp2B-14D	Protein phosphatase 2B at 14D	0.018	Mouse
Tcp-1zeta	T-cp1zeta	0.018
Slbp	Stem-loop binding protein	0.018
Prp19	CG5519 gene product from transcript CG5519-RA	0.017
CG8223	CG8223 gene product from transcript CG8223-RA	0.017
Eip63F-1	Ecdysone-induced protein 63F 1	0.017
rl	rolled	0.017
cid	centromere identifier	0.017
nocte	no circadian temperature entrainment	0.017
CG3776	CG3776 gene product from transcript CG3776-RA	0.017
exd	extradenticle	0.017
drk	downstream of receptor kinase	0.017
E2f2	E2F transcription factor 2	0.017
CG8247	CG8247 gene product from transcript CG8247-RB	0.017
Kr-h1	Kruppel homolog 1	0.017
CG3634	CG3634 gene product from transcript CG3634-RA	0.017
DNApol-alpha60	DNA polymerase alpha 60kD	0.017
Dlic	Dynein light intermediate chain	0.017
DNApol-eta	CG7143 gene product from transcript CG7143-RA	0.016
wda	will decrease acetylation	0.016
borr	borealin-related	0.016
Thor	CG8846 gene product from transcript CG8846-RA	0.016
Sld5	CG14549 gene product from transcript CG14549-RA	0.016
CG14683	CG14683 gene product from transcript CG14683-RA	0.016
plexA	plexin A	0.016
Nf-YA	Nuclear factor Y-box A	0.016
ial	IplI-aurora-like kinase	0.016
mib1	mind bomb 1	0.016
Nf1	Neurofibromin 1	0.016
lok	loki	0.016
Droj2	DnaJ-like-2	0.016
eIF-1A	Eukaryotic initiation factor 1A	0.016
par-1	CG8201 gene product from transcript CG8201-RA	0.016
scyl	scylla	0.016
Rcd4	Reduction in Cnn dots 4	0.016
Mcm6	Minichromosome maintenance 6	0.016
pit	pitchoune	0.016
CycB3	Cyclin B3	0.015	Yeast
zwilch	CG18729 gene product from transcript CG18729-RA	0.015
pon	partner of numb	0.015
CG1218	CG1218 gene product from transcript CG1218-RA	0.015
mei-9	meiotic 9	0.015
glu	gluon	0.015
His3.3B	Histone H3.3B	0.015
RPA2	Replication protein A2	0.015	Human
CG31619	CG31619 gene product from transcript CG31619-RC	0.015
dia	diaphanous	0.015
CG4699	CG4699 gene product from transcript CG4699-RJ	0.015
path	pathetic	0.015
Hus1-like	CG2525 gene product from transcript CG2525-RA	0.015
snRNP-U1-70K	small ribonucleoprotein particle U1 subunit 70K	0.015
ex	expanded	0.015
ptip	CG32133 gene product from transcript CG32133-RA	0.015
Gld2	CG5732 gene product from transcript CG5732-RA	0.015
Dfd	Deformed	0.015
Nup160	Nucleoporin 160	0.015
hipk	homeodomain interacting protein kinase	0.015
th	thread	0.014
fu	fused	0.014
nAcRalpha-80B	nicotinic Acetylcholine Receptor alpha 80B	0.014
ctp	cut up	0.014
CG3704	CG3704 gene product from transcript CG3704-RA	0.014
Spx	Spliceosomal protein on the X	0.014
Ntf-2	Nuclear transport factor-2	0.014
mus201	mutagen-sensitive 201	0.014
cnn	centrosomin	0.014
CG4849	CG4849 gene product from transcript CG4849-RA	0.014
Xpd	Xeroderma pigmentosum D	0.014
Atg1	Autophagy-specific gene 1	0.014
tefu	telomere fusion	0.014
CG31998	CG31998 gene product from transcript CG31998-RA	0.014
hiw	highwire	0.014
shtd	shattered	0.014
eff	effete	0.014
CG6227	CG6227 gene product from transcript CG6227-RA	0.014
tws	twins	0.014
DMAP1	CG11132 gene product from transcript CG11132-RA	0.014
Mcm5	Minichromosome maintenance 5	0.014
msk	moleskin	0.014
Caf1	Chromatin assembly factor 1 subunit	0.014
Taspase1	Taspase 1	0.014
CG12945	CG12945 gene product from transcript CG12945-RB	0.014
Tctp	Translationally controlled tumor protein	0.013
CG4980	CG4980 gene product from transcript CG4980-RA	0.013
Fer2LCH	Ferritin 2 light chain homologue	0.013
CG15514	CG15514 gene product from transcript CG15514-RA	0.013
CycK	Cyclin K	0.013
rux	roughex	0.013
pim	pimples	0.013
E(bx)	Enhancer of bithorax	0.013
CanB	Calcineurin B	0.013
Tis11	Tis11 homolog	0.013
Sry-delta	Serendipity delta	0.013
RagA	CG11968 gene product from transcript CG11968-RA	0.013
Tbp	TATA binding protein	0.013
CG13043	CG13043 gene product from transcript CG13043-RA	0.013
RpS14a	Ribosomal protein S14a	0.013
CG2926	CG2926 gene product from transcript CG2926-RA	0.013
yps	ypsilon schachtel	0.013
Rbf2	Retinoblastoma-family protein 2	0.013
scny	scrawny	0.013
CG10417	CG10417 gene product from transcript CG10417-RA	0.013
zfh1	Zn finger homeodomain 1	0.013
CG8485	CG8485 gene product from transcript CG8485-RA	0.013
CG12026	CG12026 gene product from transcript CG12026-RB	0.013
slmb	supernumerary limbs	0.013
Gie	novel GTPase indispensable for equal segregation of chromosomes	0.013
CG17343	CG17343 gene product from transcript CG17343-RA	0.013
Fen1	Flap endonuclease 1	0.013
eIF4E-7	CG32859 gene product from transcript CG32859-RA	0.013
Uev1A	CG10640 gene product from transcript CG10640-RA	0.012
cv	crossveinless	0.012
CG10414	CG10414 gene product from transcript CG10414-RA	0.012
Mef2	Myocyte enhancer factor 2	0.012
Eps-15	Epidermal growth factor receptor pathway substrate clone 15	0.012
Hsc70-3	Heat shock protein cognate 3	0.012
CG1021	CG1021 gene product from transcript CG1021-RE	0.012
CG7379	CG7379 gene product from transcript CG7379-RA	0.012
Snr1	Snf5-related 1	0.012
oys	oysgedart	0.012
Atg6	Autophagy-specific gene 6	0.012
jigr1	jing interacting gene regulatory 1	0.012
Su(H)	Suppressor of Hairless	0.012
Gug	Grunge	0.012
G-oalpha47A	G protein oalpha 47A	0.012
CG16838	CG16838 gene product from transcript CG16838-RC	0.012
Incenp	Inner centromere protein	0.012
MEP-1	CG1244 gene product from transcript CG1244-RG	0.012
Nxt1	NTF2-related export protein 1	0.012
polo	CG12306 gene product from transcript CG12306-RA	0.012
tld	tolloid	0.012
robo	roundabout	0.012
pum	pumilio	0.012
Dat	Dopamine N acetyltransferase	0.012
CG9821	CG9821 gene product from transcript CG9821-RB	0.012
CG14561	CG14561 gene product from transcript CG14561-RA	0.012
sima	similar	0.012
L	Lobe	0.012
mld	molting defective	0.012
Myb	Myb oncogene-like	0.012	Mouse
Pep	Protein on ecdysone puffs	0.012
Cks85A	Cyclin-dependent kinase subunit 85A	0.012
sut1	sugar transporter 1	0.011
Dcr-1	Dicer-1	0.011
SRm160	CG11274 gene product from transcript CG11274-RA	0.011
DNApol-alpha50	DNA polymerase alpha 50kD	0.011
BG4	CG12297 gene product from transcript CG12297-RA	0.011
aur	aurora	0.011
ftz-f1	ftz transcription factor 1	0.011
ush	u-shaped	0.011
PPP4R2r	Protein phosphatase 4 regulatory subunit 2-related protein	0.011
CG9839	CG9839 gene product from transcript CG9839-RA	0.011
RpL39	Ribosomal protein L39	0.011
Su(fu)	Suppressor of fused	0.011
Smg1	CG32743 gene product from transcript CG32743-RA	0.011
Amun	CG2446 gene product from transcript CG2446-RB	0.011
lola	longitudinals lacking	0.011
Sce	Sex combs extra	0.011
Rpt3	CG16916 gene product from transcript CG16916-RA	0.011
Df31	Decondensation factor 31	0.011
CG4567	CG4567 gene product from transcript CG4567-RA	0.011
WDR79	WD repeat domain 79 homolog	0.011
Glut1	Glucose transporter 1	0.011
GABA-B-R2	metabotropic GABA-B receptor subtype 2	0.011
Mcm10	Sensitized chromosome inheritance modifier 19	0.011
arm	armadillo	0.011
mol	moladietz	0.011
CG10741	CG10741 gene product from transcript CG10741-RB	0.011
mle	maleless	0.011
CG17002	CG17002 gene product from transcript CG17002-RB	0.011
Lam	Lamin	0.011
CG33229	CG33229 gene product from transcript CG33229-RA	0.011
Cp190	Centrosomal protein 190kD	0.011
PSR	phosphatidylserine receptor	0.011
RpL24	Ribosomal protein L24	0.011
CycT	Cyclin T	0.011
RhoGEF4	CG8606 gene product from transcript CG8606-RA	0.011
CG12316	CG12316 gene product from transcript CG12316-RB	0.011
bcd	bicoid	0.011
RpL22	Ribosomal protein L22	0.011
HIP-R	Hsc/Hsp70-interacting protein related	0.010
SmD1	Small ribonucleoprotein particle protein SmD1	0.010
dlt	discs lost	0.010
cv-c	crossveinless c	0.010
nonA	no on or off transient A	0.010
Mipp2	Multiple inositol polyphosphate phosphatase 2	0.010
Dref	DNA replication-related element factor	0.010
ran	CG1404 gene product from transcript CG1404-RB	0.010
DNApol-alpha73	DNA polymerase alpha 73kD	0.010
CG1910	CG1910 gene product from transcript CG1910-RB	0.010
Nup153	Nucleoporin 153	0.010
tup	tailup	0.010
sra	sarah	0.010
Mcm7	Minichromosome maintenance 7	0.010
CrebB-17A	Cyclic-AMP response element binding protein B at 17A	0.010
unc-119	CG1659 gene product from transcript CG1659-RA	0.010
CG4788	CG4788 gene product from transcript CG4788-RA	0.010
CG5174	CG5174 gene product from transcript CG5174-RM	0.010
CG9418	CG9418 gene product from transcript CG9418-RA	0.010
CG7839	CG7839 gene product from transcript CG7839-RA	0.010