IMP: Integrative Multi-species Prediction

Drosophila melanogaster

25 genes annotated in fly

Multi-species View

positive regulation of protein kinase activity

GO:0045860

Any process that activates or increases the frequency, rate or extent of protein kinase activity.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of protein kinase activity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of protein kinase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Ras85D	Ras oncogene at 85D	0.971	Human
dsh	dishevelled	0.852	Human Mouse
hep	hemipterous	0.736
rl	rolled	0.729
ttk	tramtrack	0.696
Akt1	CG4006 gene product from transcript CG4006-RA	0.673	Human
bsk	basket	0.577
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.497
G-oalpha47A	G protein oalpha 47A	0.485
Sara	Smad anchor for receptor activation	0.399
kay	kayak	0.396
Rho1	CG8416 gene product from transcript CG8416-RB	0.346
mbc	myoblast city	0.302
Rac1	CG2248 gene product from transcript CG2248-RA	0.285
Mad	Mothers against dpp	0.272
par-1	CG8201 gene product from transcript CG8201-RA	0.271
spi	spitz	0.265	Fly
Sin3A	CG8815 gene product from transcript CG8815-RC	0.248
aop	anterior open	0.238
CkIIalpha	Casein kinase II alpha subunit	0.218
msn	misshapen	0.184	Human Mouse
stck	steamer duck	0.168
Cip4	CG15015 gene product from transcript CG15015-RA	0.156
dap	dacapo	0.156
Su(H)	Suppressor of Hairless	0.152
Pkn	Protein kinase related to protein kinase N	0.151
X11L	CG5675 gene product from transcript CG5675-RB	0.151
HLHmgamma	E(spl) region transcript mgamma	0.151	Zebrafish
Fhos	CG42610 gene product from transcript CG42610-RC	0.146
PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	0.141
puc	puckered	0.138
rhea	CG6831 gene product from transcript CG6831-RA	0.137
CG5794	CG5794 gene product from transcript CG5794-RB	0.124
spas	spastin	0.124
chico	CG5686 gene product from transcript CG5686-RB	0.123
cta	concertina	0.119
tws	twins	0.113
sgl	sugarless	0.108
babo	baboon	0.107	Human
HLHmdelta	E(spl) region transcript mdelta	0.098	Zebrafish
Cdk4	Cyclin-dependent kinase 4	0.097
HLHm7	E(spl) region transcript m7	0.094	Zebrafish
Rac2	CG8556 gene product from transcript CG8556-RA	0.090	Fly
Imp	IGF-II mRNA-binding protein	0.085
Pten	CG5671 gene product from transcript CG5671-RB	0.084
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.081
phl	pole hole	0.079	Rat
HLHmbeta	E(spl) region transcript mbeta	0.079	Zebrafish
CycE	Cyclin E	0.079
vg	vestigial	0.077
CG8155	CG8155 gene product from transcript CG8155-RA	0.076
WASp	CG1520 gene product from transcript CG1520-RA	0.076
dia	diaphanous	0.075
Mcm6	Minichromosome maintenance 6	0.075
jeb	jelly belly	0.075
Tom	Twin of m4	0.075
pyd	polychaetoid	0.073
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.070
S6k	RPS6-p70-protein kinase	0.065
Smg1	CG32743 gene product from transcript CG32743-RA	0.064
yki	yorkie	0.062
Dad	Daughters against dpp	0.058
sr	stripe	0.058
mys	myospheroid	0.058
sd	scalloped	0.056	Mouse
dock	dreadlocks	0.055
cpb	capping protein beta	0.055
lqf	liquid facets	0.053
hbs	hibris	0.052
Adar	Adenosine deaminase acting on RNA	0.052
L	Lobe	0.052
Rala	Ras-related protein	0.051
Galpha49B	G protein alpha49B	0.051
Myo31DF	Myosin 31DF	0.049
Atg1	Autophagy-specific gene 1	0.049
E(spl)	Enhancer of split	0.049	Zebrafish
CtBP	C-terminal Binding Protein	0.048
sax	saxophone	0.048
l(2)gl	lethal (2) giant larvae	0.046
ovo	CG6824 gene product from transcript CG6824-RE	0.046
p38b	CG7393 gene product from transcript CG7393-RA	0.046
rap	retina aberrant in pattern	0.045
btl	breathless	0.044
Myb	Myb oncogene-like	0.042
drk	downstream of receptor kinase	0.042
Hop	Hsp70/Hsp90 organizing protein homolog	0.041
HLHm3	E(spl) region transcript m3	0.041	Zebrafish
rok	Rho-kinase	0.040
Smox	Smad on X	0.040
cert	ceramide transfer protein	0.039
pyr	pyramus	0.039
inaD	inactivation no afterpotential D	0.038
malpha	E(spl) region transcript malpha	0.038
ecd	ecdysoneless	0.038
Mtl	Mig-2-like	0.037	Fly
Wnk	CG7177 gene product from transcript CG7177-RA	0.036
ths	thisbe	0.036
Tl	Toll	0.035
dm	diminutive	0.035
rst	roughest	0.035
nej	nejire	0.035
ru	roughoid	0.035
Rab5	Rab-protein 5	0.035
wg	wingless	0.034
Fak56D	Focal Adhesion Kinase	0.034	Human Mouse Rat
RagA	CG11968 gene product from transcript CG11968-RA	0.034
Apc	APC-like	0.034
HLHm5	E(spl) region transcript m5	0.033	Zebrafish
fz	frizzled	0.033
Cdlc2	Cytoplasmic dynein light chain 2	0.033
debcl	death executioner Bcl-2 homologue	0.031
Rab30	CG9100 gene product from transcript CG9100-RB	0.031
mi	minus	0.031
Nrx-IV	Neurexin IV	0.031
Met	Methoprene-tolerant	0.030
Rbp6	RNA-binding protein 6	0.029
Cul-5	Cullin-5	0.029
mtm	myotubularin	0.029
CycA	Cyclin A	0.029
dys	dysfusion	0.028
Hs6st	Heparan sulfate 6-O-sulfotransferase	0.028
baz	bazooka	0.028
ex	expanded	0.027
Mrtf	Myocardin-related transcription factor	0.027
Khc	Kinesin heavy chain	0.026
wts	warts	0.026
Lis-1	Lissencephaly-1	0.026
wun	wunen	0.026
pnt	pointed	0.025
ebi	CG4063 gene product from transcript CG4063-RA	0.025
pan	pangolin	0.025
ed	echinoid	0.025
unc-13	CG2999 gene product from transcript CG2999-RA	0.024
Marf	Mitochondrial assembly regulatory factor	0.024
dik	diskette	0.024
p53	CG33336 gene product from transcript CG33336-RB	0.023
ari-2	ariadne 2	0.023
Eip71CD	Ecdysone-induced protein 28/29kD	0.023
seq	sequoia	0.023
Tsc1	CG6147 gene product from transcript CG6147-RA	0.023
mtt	mangetout	0.022
Fer1HCH	Ferritin 1 heavy chain homologue	0.022
NijA	Ninjurin A	0.022
LanB2	Laminin B2	0.022
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.022
smo	smoothened	0.022
Stim	Stromal interaction molecule	0.022
Rab11	Rab-protein 11	0.022
gish	gilgamesh	0.022
Klp64D	Kinesin-like protein at 64D	0.021
Prosap	CG30483 gene product from transcript CG30483-RA	0.021
nct	nicastrin	0.021
Alk	CG8250 gene product from transcript CG8250-RA	0.021
ase	asense	0.021
foxo	forkhead box, sub-group O	0.021
cindr	CIN85 and CD2AP orthologue	0.021
And	Androcam	0.021
gek	genghis khan	0.021
Dl	Delta	0.020
csw	corkscrew	0.020	Mouse
Cdc42	CG12530 gene product from transcript CG12530-RA	0.020
Gr28b	Gustatory receptor 28b	0.020
drpr	draper	0.020
sina	seven in absentia	0.020
Pk61C	Protein kinase 61C	0.020	Human
CG9867	CG9867 gene product from transcript CG9867-RA	0.020
stumps	CG31317 gene product from transcript CG31317-RC	0.020
trio	CG18214 gene product from transcript CG18214-RA	0.019
R	Roughened	0.019	Rat
Lar	Leukocyte-antigen-related-like	0.019
Ptp61F	Protein tyrosine phosphatase 61F	0.019
por	porcupine	0.019
Thor	CG8846 gene product from transcript CG8846-RA	0.019
dos	daughter of sevenless	0.018	Mouse
loqs	loquacious	0.018
grk	gurken	0.018
Ras64B	Ras oncogene at 64B	0.018
nvy	nervy	0.018
chic	chickadee	0.018
SNF1A	SNF1A/AMP-activated protein kinase	0.018
Dab	Disabled	0.017	Mouse
cutlet	CG33122 gene product from transcript CG33122-RA	0.017
Art6	Arginine methyltransferase 6	0.017
rictor	rapamycin-insensitive companion of Tor	0.017
CG33523	CG33523 gene product from transcript CG33523-RD	0.017
Socs36E	Suppressor of cytokine signaling at 36E	0.017
Akap200	A kinase anchor protein 200	0.017
l(3)82Fd	CG32464 gene product from transcript CG32464-RR	0.017
nmo	nemo	0.017
m2	E(spl) region transcript m2	0.017
bnl	branchless	0.017
cnk	connector enhancer of ksr	0.017
stai	stathmin	0.017
Jra	Jun-related antigen	0.016
trc	tricornered	0.016
egh	egghead	0.016
fng	fringe	0.016
Gyc76C	Guanylyl cyclase at 76C	0.016
sev	sevenless	0.016	Fly
Mst89B	CG6864 gene product from transcript CG6864-RA	0.016
sc	scute	0.016
Timp	Tissue inhibitor of metalloproteases	0.016
slow	slowdown	0.016
pnut	peanut	0.016
LamC	Lamin C	0.016
kibra	kibra ortholog	0.016
bves	CG32513 gene product from transcript CG32513-RA	0.016
Dhc64C	Dynein heavy chain 64C	0.016
Ephrin	CG1862 gene product from transcript CG1862-RA	0.016
Hph	HIF prolyl hydroxylase	0.016
ci	cubitus interruptus	0.016
CG1021	CG1021 gene product from transcript CG1021-RE	0.016
vari	varicose	0.015
wb	wing blister	0.015
trpml	transient receptor potential mucolipin	0.015
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.015
Src42A	Src oncogene at 42A	0.015	Fly
twi	twist	0.015
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.015
psq	pipsqueak	0.015
Gmd	GDP-mannose 4,6-dehydratase	0.015
InR	Insulin-like receptor	0.015	Human Fly
stg	string	0.015	Mouse
Rh3	Rhodopsin 3	0.015
sano	serrano	0.015
Mmp2	Matrix metalloproteinase 2	0.014
Plc21C	Phospholipase C at 21C	0.014
Atf-2	Activating transcription factor-2	0.014
MP1	Melanization Protease 1	0.014
Hsf	Heat shock factor	0.014
CG14219	CG14219 gene product from transcript CG14219-RA	0.014
galectin	CG11372 gene product from transcript CG11372-RA	0.014
Corin	CG2105 gene product from transcript CG2105-RB	0.014
nudE	CG8104 gene product from transcript CG8104-RB	0.014
c11.1	CG12132 gene product from transcript CG12132-RA	0.014
rtGEF	rho-type guanine exchange factor	0.014
ninaE	neither inactivation nor afterpotential E	0.014
numb	CG3779 gene product from transcript CG3779-RB	0.014
RhoGAP15B	CG4937 gene product from transcript CG4937-RC	0.014
Cks30A	Cyclin-dependent kinase subunit 30A	0.014
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.014
kuz	kuzbanian	0.013
CG8334	CG8334 gene product from transcript CG8334-RA	0.013
cmet	CENP-meta	0.013
E2f2	E2F transcription factor 2	0.013
CG9063	CG9063 gene product from transcript CG9063-RA	0.013
mth	methuselah	0.013
Sbf	SET domain binding factor	0.013
CG8128	CG8128 gene product from transcript CG8128-RA	0.013
rdx	roadkill	0.013
tacc	transforming acidic coiled-coil protein	0.013
shg	shotgun	0.013
Ric	Ras which interacts with Calmodulin	0.013
hipk	homeodomain interacting protein kinase	0.013
myoglianin	CG1838 gene product from transcript CG1838-RD	0.013
c(3)G	crossover suppressor on 3 of Gowen	0.013
htl	heartless	0.013	Human Fly
CG4116	CG4116 gene product from transcript CG4116-RA	0.013
boi	brother of iHog	0.013
dpn	deadpan	0.013
RhoGEF2	CG9635 gene product from transcript CG9635-RF	0.013
slmb	supernumerary limbs	0.013
Vsx2	CG33980 gene product from transcript CG33980-RA	0.013
enc	encore	0.013
Ilp4	Insulin-like peptide 4	0.013
Cbl	CG7037 gene product from transcript CG7037-RB	0.013
Tsp	Thrombospondin	0.013	Human
Gycalpha99B	Guanylyl cyclase alpha-subunit at 99B	0.013
insc	inscuteable	0.013
ttv	tout-velu	0.013
Ten-m	Tenascin major	0.013
Mpk2	CG5475 gene product from transcript CG5475-RB	0.013
ens	ensconsin	0.012
flw	flapwing	0.012
luna	CG33473 gene product from transcript CG33473-RB	0.012
POSH	Plenty of SH3s	0.012
shrb	shrub	0.012
mask	multiple ankyrin repeats single KH domain	0.012
scu	scully	0.012
ftz-f1	ftz transcription factor 1	0.012
CG1347	CG1347 gene product from transcript CG1347-RB	0.012
S6kII	RPS6-protein kinase-II	0.012
da	daughterless	0.012
Fas1	Fasciclin 1	0.012
p120ctn	Adherens junction protein p120	0.012
mGluRA	metabotropic glutamate receptor	0.012
frtz	fritz	0.012
os	outstretched	0.012
Bj1	Bj1 protein	0.012
CG5857	CG5857 gene product from transcript CG5857-RA	0.012
kis	kismet	0.012
pie	pineapple eye	0.012
BobA	Brother of Bearded A	0.012
ric8a	CG15797 gene product from transcript CG15797-RA	0.012
polo	CG12306 gene product from transcript CG12306-RA	0.012
Rgl	Ral guanine nucleotide exchange factor	0.012
Mkp3	Mitogen-activated protein kinase phosphatase 3	0.012
Shc	SHC-adaptor protein	0.012	Human Mouse Rat
syd	sunday driver	0.012	Mouse
Unc-76	CG3981 gene product from transcript CG3981-RB	0.012
ena	enabled	0.012
EndoGI	Endonuclease G inhibitor	0.011
olf413	CG12673 gene product from transcript CG12673-RB	0.011
CG4168	CG4168 gene product from transcript CG4168-RA	0.011
Fatp	Fatty acid (long chain) transport protein	0.011	Mouse
kek1	kekkon-1	0.011
fy	fuzzy	0.011
orb	oo18 RNA-binding protein	0.011
rin	rasputin	0.011
emc	extra macrochaetae	0.011
G-salpha60A	G protein salpha 60A	0.011
CG4973	CG4973 gene product from transcript CG4973-RA	0.011
yrt	yurt	0.011
Nek2	CG17256 gene product from transcript CG17256-RA	0.011
trk	trunk	0.011
Tab2	TAK1-associated binding protein 2	0.011
Mmp1	Matrix metalloproteinase 1	0.011
Pur-alpha	Purine-rich binding protein-alpha	0.011
Grip	Glutamate receptor binding protein	0.011
krz	kurtz	0.011
scb	scab	0.011
CG30372	CG30372 gene product from transcript CG30372-RC	0.011
ham	hamlet	0.011
PHDP	Putative homeodomain protein	0.011
Spn31A	Serpin 31A	0.011
tefu	telomere fusion	0.011
cdc2c	CG10498 gene product from transcript CG10498-RC	0.011
Vhl	von Hippel-Lindau	0.011
alpha-Man-IIb	CG4606 gene product from transcript CG4606-RA	0.011
mbt	mushroom bodies tiny	0.011
e	ebony	0.011
wee	CG4488 gene product from transcript CG4488-RA	0.011
sinu	sinuous	0.011
Hs3st-A	Heparan sulfate 3-O sulfotransferase-A	0.011
sima	similar	0.011
ird1	immune response deficient 1	0.011
dally	division abnormally delayed	0.011
beat-Ia	beaten path Ia	0.011
tap	target of Poxn	0.011
vav	CG7893 gene product from transcript CG7893-RB	0.011
NFAT	NFAT homolog	0.011
pros	prospero	0.011
Zn72D	CG5215 gene product from transcript CG5215-RB	0.010
Vps33B	Vacuolar protein sorting 33B	0.010
rasp	CG11495 gene product from transcript CG11495-RA	0.010
CG9691	CG9691 gene product from transcript CG9691-RB	0.010
bsh	brain-specific homeobox	0.010
Cat	Catalase	0.010
Lnk	CG17367 gene product from transcript CG17367-RC	0.010
CG42256	CG42256 gene product from transcript CG42256-RH	0.010
kel	kelch	0.010
ken	ken and barbie	0.010
CG34404	CG34404 gene product from transcript CG34404-RD	0.010
mub	mushroom-body expressed	0.010
cals	calsyntenin-1	0.010
Gap1	GTPase-activating protein 1	0.010
CG3573	CG3573 gene product from transcript CG3573-RA	0.010