IMP: Integrative Multi-species Prediction

Drosophila melanogaster

29 genes annotated in fly

negative regulation of protein modification process

Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein modification process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of protein modification process" (in gray)

Name	Description	Probability	Func Analog Organism
drk	downstream of receptor kinase	0.426
EndoGI	Endonuclease G inhibitor	0.372
tws	twins	0.362
egh	egghead	0.360
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.352
rho	rhomboid	0.263
Pten	CG5671 gene product from transcript CG5671-RB	0.197	Human
trx	trithorax	0.184
Ubx	Ultrabithorax	0.144
G-oalpha47A	G protein oalpha 47A	0.144
Hsp27	Heat shock protein 27	0.133
Mad	Mothers against dpp	0.130
rap	retina aberrant in pattern	0.125
Cdc42	CG12530 gene product from transcript CG12530-RA	0.114
argos	CG4531 gene product from transcript CG4531-RA	0.111
wit	wishful thinking	0.108
Sara	Smad anchor for receptor activation	0.098
stck	steamer duck	0.097
Pka-C1	cAMP-dependent protein kinase 1	0.095
sog	short gastrulation	0.093
dnc	dunce	0.091	Mouse
Ras85D	Ras oncogene at 85D	0.088
Hsp83	Heat shock protein 83	0.087
spi	spitz	0.081
Arp66B	Actin-related protein 66B	0.080
rut	rutabaga	0.075
X11L	CG5675 gene product from transcript CG5675-RB	0.075
shn	schnurri	0.074
smt3	CG4494 gene product from transcript CG4494-RA	0.074
Pp1-87B	Protein phosphatase 1 at 87B	0.072
wun	wunen	0.072	Human Mouse
ash2	absent, small, or homeotic discs 2	0.065
Akap200	A kinase anchor protein 200	0.064
rl	rolled	0.063
Dad	Daughters against dpp	0.062	Human Mouse
pnut	peanut	0.060
Abl	Abl tyrosine kinase	0.059	Human
fu	fused	0.059
ena	enabled	0.055
zfh1	Zn finger homeodomain 1	0.054
inaD	inactivation no afterpotential D	0.053
eya	eyes absent	0.052
sbb	scribbler	0.052
htl	heartless	0.050
Smox	Smad on X	0.050
Vha100-1	CG1709 gene product from transcript CG1709-RF	0.047
cno	canoe	0.046
shg	shotgun	0.046
rok	Rho-kinase	0.044
lace	CG4162 gene product from transcript CG4162-RA	0.044
enc	encore	0.042
hpo	hippo	0.041
CadN	Cadherin-N	0.041
scb	scab	0.041
par-1	CG8201 gene product from transcript CG8201-RA	0.040
kis	kismet	0.037
chb	chromosome bows	0.037
Six4	CG3871 gene product from transcript CG3871-RA	0.037
Sulf1	Sulfated	0.037
chico	CG5686 gene product from transcript CG5686-RB	0.037
p53	CG33336 gene product from transcript CG33336-RB	0.036	Mouse
G-salpha60A	G protein salpha 60A	0.036
Wnk	CG7177 gene product from transcript CG7177-RA	0.035	Rat
Gap1	GTPase-activating protein 1	0.035
Su(H)	Suppressor of Hairless	0.035
CSN5	COP9 complex homolog subunit 5	0.035
wdb	widerborst	0.034
sax	saxophone	0.034
Appl	beta amyloid protein precursor-like	0.033
Apc2	Adenomatous polyposis coli tumor suppressor homolog 2	0.033	Human
CG13253	CG13253 gene product from transcript CG13253-RB	0.032
robo	roundabout	0.032
trp	transient receptor potential	0.032
Stam	Signal transducing adaptor molecule	0.032
CycA	Cyclin A	0.031
PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	0.030
ninaE	neither inactivation nor afterpotential E	0.030
Rac1	CG2248 gene product from transcript CG2248-RA	0.030
GckIII	Germinal centre kinase III	0.030
sty	sprouty	0.030	Human Mouse
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.029
Med	Medea	0.029
skd	skuld	0.029
CG5931	CG5931 gene product from transcript CG5931-RA	0.029
smo	smoothened	0.029
ci	cubitus interruptus	0.029
rdgB	retinal degeneration B	0.028
Dcr-2	Dicer-2	0.027
Tbh	Tyramine beta hydroxylase	0.027
hts	hu li tai shao	0.026
CG31457	CG31457 gene product from transcript CG31457-RB	0.026
loqs	loquacious	0.026
Ubqn	Ubiquilin	0.026
put	punt	0.026
cher	cheerio	0.026
Pkn	Protein kinase related to protein kinase N	0.026	Mouse
gish	gilgamesh	0.026
bif	bifocal	0.026
ago	archipelago	0.025
amn	amnesiac	0.025
Met	Methoprene-tolerant	0.024
Stim	Stromal interaction molecule	0.024
egl	egalitarian	0.024
gig	gigas	0.024	Mouse Rat
tai	taiman	0.024
ru	roughoid	0.024
CkIalpha	Casein kinase Ialpha	0.023
Pk61C	Protein kinase 61C	0.023	Human
arm	armadillo	0.023	Human
Gprk2	G protein-coupled receptor kinase 2	0.023
Src42A	Src oncogene at 42A	0.022
hipk	homeodomain interacting protein kinase	0.022	Mouse
sgl	sugarless	0.022
Ras64B	Ras oncogene at 64B	0.022
hbs	hibris	0.022
wls	wntless	0.022
hh	hedgehog	0.022
pex16	peroxin 16	0.022
oys	oysgedart	0.021
Dcp-1	Death caspase-1	0.021
aux	auxillin	0.021
numb	CG3779 gene product from transcript CG3779-RB	0.021
CG9705	CG9705 gene product from transcript CG9705-RA	0.021
coro	CG9446 gene product from transcript CG9446-RC	0.021
Su(z)2	Suppressor of zeste 2	0.021
sds22	CG5851 gene product from transcript CG5851-RA	0.021
Rbsn-5	Rabenosyn-5	0.021
Socs36E	Suppressor of cytokine signaling at 36E	0.020	Human
DAAM	Dishevelled Associated Activator of Morphogenesis	0.020
NFAT	NFAT homolog	0.020
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.019
pr-set7	CG3307 gene product from transcript CG3307-RC	0.019
baz	bazooka	0.019	Mouse
dco	discs overgrown	0.019
lt	light	0.019
ttv	tout-velu	0.019
LanB1	CG7123 gene product from transcript CG7123-RA	0.019
for	foraging	0.018
mol	moladietz	0.018
LanA	Laminin A	0.018
Klp64D	Kinesin-like protein at 64D	0.018
fzy	fizzy	0.018
tin	tinman	0.018
Bre1	CG10542 gene product from transcript CG10542-RA	0.018
cg	combgap	0.018
wds	will die slowly	0.018
bchs	blue cheese	0.018
not	non-stop	0.018
drongo	CG3365 gene product from transcript CG3365-RH	0.018
CG13405	CG13405 gene product from transcript CG13405-RA	0.018
brn	brainiac	0.018
klg	klingon	0.018
CG10083	CG10083 gene product from transcript CG10083-RA	0.017
star1	allatostatin C receptor 1	0.017
hep	hemipterous	0.017
Gef26	CG9491 gene product from transcript CG9491-RB	0.017
Snoo	Sno oncogene	0.017
ninaB	neither inactivation nor afterpotential B	0.017
mth	methuselah	0.017
capt	capulet	0.017
SoxN	SoxNeuro	0.017
Spf45	CG17540 gene product from transcript CG17540-RB	0.017
rictor	rapamycin-insensitive companion of Tor	0.016
btl	breathless	0.016
A16	CG9933 gene product from transcript CG9933-RA	0.016
Ube3a	Ubiquitin protein ligase E3A	0.016
eas	easily shocked	0.016
Jafrac1	thioredoxin peroxidase 1	0.016
ap	apterous	0.016
drpr	draper	0.016
Hip14	Huntingtin-interacting protein 14	0.016
grk	gurken	0.016
Ptp10D	Protein tyrosine phosphatase 10D	0.016	Human Mouse
Dhod	Dihydroorotate dehydrogenase	0.016
Egfr	Epidermal growth factor receptor	0.015
tld	tolloid	0.015
Jra	Jun-related antigen	0.015	Mouse
slmb	supernumerary limbs	0.015
Tsp	Thrombospondin	0.015
lkb1	CG9374 gene product from transcript CG9374-RJ	0.015
AGO1	Argonaute-1	0.015
MED19	Mediator complex subunit 19	0.015
Cip4	CG15015 gene product from transcript CG15015-RA	0.015
babo	baboon	0.015
wb	wing blister	0.015
Shc	SHC-adaptor protein	0.015
TER94	CG2331 gene product from transcript CG2331-RA	0.015
sqd	squid	0.015
bi	bifid	0.015
laza	lazaro	0.015
Rac2	CG8556 gene product from transcript CG8556-RA	0.015
so	sine oculis	0.014
neb	nebbish	0.014
sim	single-minded	0.014
pUf68	poly U binding factor 68kD	0.014
CG1553	CG1553 gene product from transcript CG1553-RA	0.014
trpl	trp-like	0.014
msn	misshapen	0.014
ebi	CG4063 gene product from transcript CG4063-RA	0.014
dally	division abnormally delayed	0.014
Phm	Peptidylglycine-alpha-hydroxylating monooxygenase	0.014
slpr	slipper	0.014
Mnn1	Menin 1	0.014
rogdi	CG7725 gene product from transcript CG7725-RB	0.014
Rho1	CG8416 gene product from transcript CG8416-RB	0.014
Wnt4	Wnt oncogene analog 4	0.014
Eip71CD	Ecdysone-induced protein 28/29kD	0.014
neur	neuralized	0.014
krz	kurtz	0.014
CSN4	COP9 complex homolog subunit 4	0.014
jeb	jelly belly	0.014
Ack	CG14992 gene product from transcript CG14992-RA	0.014	Fly
cpa	capping protein alpha	0.013
Atg1	Autophagy-specific gene 1	0.013
Cdk4	Cyclin-dependent kinase 4	0.013
CG8931	CG8931 gene product from transcript CG8931-RA	0.013
out	outsiders	0.013
rost	rolling stone	0.013
cln3	CG5582 gene product from transcript CG5582-RA	0.013
Fak56D	Focal Adhesion Kinase	0.013
dos	daughter of sevenless	0.013
Hrb87F	Heterogeneous nuclear ribonucleoprotein at 87F	0.013
mbo	members only	0.013
tsh	teashirt	0.013
slou	slouch	0.013
C3G	CG42328 gene product from transcript CG42328-RC	0.013
tgo	tango	0.013
Mcm10	Sensitized chromosome inheritance modifier 19	0.013
CG9003	CG9003 gene product from transcript CG9003-RD	0.013
Syx7	Syntaxin 7	0.013
CG1021	CG1021 gene product from transcript CG1021-RE	0.013
exba	extra bases	0.013
NetB	Netrin-B	0.013
eEF1delta	CG4912 gene product from transcript CG4912-RB	0.013
Patr-1	Protein associated with topo II related - 1	0.013
Tom	Twin of m4	0.013
Tsc1	CG6147 gene product from transcript CG6147-RA	0.013
jing	CG9397 gene product from transcript CG9397-RI	0.013
otk	off-track	0.013
dsh	dishevelled	0.012	Human Mouse
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.012
5-HT1A	Serotonin receptor 1A	0.012
Fs	Follistatin	0.012
sr	stripe	0.012	Worm
CG17107	CG17107 gene product from transcript CG17107-RA	0.012
pigeon	CG10739 gene product from transcript CG10739-RB	0.012
rhea	CG6831 gene product from transcript CG6831-RA	0.012
SRPK	CG8174 gene product from transcript CG8174-RA	0.012
insc	inscuteable	0.012
I-2	Inhibitor-2	0.012
cv-2	crossveinless 2	0.012
RanBPM	Ran-binding protein M	0.012
Grip	Glutamate receptor binding protein	0.012
CG13636	CG13636 gene product from transcript CG13636-RB	0.012
Tak1	TGF-beta activated kinase 1	0.012
CG9238	CG9238 gene product from transcript CG9238-RA	0.012
CG18292	CG18292 gene product from transcript CG18292-RA	0.012
pum	pumilio	0.012
CG32372	CG32372 gene product from transcript CG32372-RA	0.012
rst	roughest	0.012	Mouse
Hrb98DE	Heterogeneous nuclear ribonucleoprotein at 98DE	0.012
ninaC	neither inactivation nor afterpotential C	0.012
Hsc70-4	Heat shock protein cognate 4	0.011	Human
Pde8	Phosphodiesterase 8	0.011
ex	expanded	0.011
CG9005	CG9005 gene product from transcript CG9005-RB	0.011
disp	dispatched	0.011
CG18347	CG18347 gene product from transcript CG18347-RA	0.011
ics	icarus	0.011
Mob2	CG11711 gene product from transcript CG11711-RC	0.011
Smr	Smrter	0.011
ninaA	neither inactivation nor afterpotential A	0.011
Hs6st	Heparan sulfate 6-O-sulfotransferase	0.011
rpr	reaper	0.011
sqz	squeeze	0.011
jar	jaguar	0.011
A2bp1	Ataxin-2 binding protein 1	0.011
CG42629	CG42629 gene product from transcript CG42629-RB	0.011
CycD	Cyclin D	0.011
elm	ethanol sensitive with low memory	0.011	Rat
Gbeta76C	G protein beta-subunit 76C	0.011
gammaTub23C	gamma-Tubulin at 23C	0.011
Mical	Molecule interacting with CasL	0.011	Mouse
tkv	thickveins	0.011
CG7967	CG7967 gene product from transcript CG7967-RA	0.011
CG12207	CG12207 gene product from transcript CG12207-RB	0.011
wapl	wings apart-like	0.011
Ada2b	CG9638 gene product from transcript CG9638-RA	0.011
CG14005	CG14005 gene product from transcript CG14005-RA	0.011
NiPp1	Nuclear inhibitor of Protein phosphatase 1	0.011
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.011
hth	homothorax	0.011
CG5190	CG5190 gene product from transcript CG5190-RA	0.011
synj	synaptojanin	0.011
qua	quail	0.011
fj	four-jointed	0.011
vri	vrille	0.011
rump	rumpelstiltskin	0.011
yl	yolkless	0.011
Hsp26	Heat shock protein 26	0.011	Mouse
cindr	CIN85 and CD2AP orthologue	0.011
zfh2	Zn finger homeodomain 2	0.011
Doc2	Dorsocross2	0.011
foxo	forkhead box, sub-group O	0.011
Lnk	CG17367 gene product from transcript CG17367-RC	0.011
crol	crooked legs	0.011
TORC	CG6064 gene product from transcript CG6064-RA	0.011
CG7357	CG7357 gene product from transcript CG7357-RA	0.011
shi	shibire	0.011
Mi-2	CG8103 gene product from transcript CG8103-RA	0.011
Z600	CG17962 gene product from transcript CG17962-RA	0.011
Uev1A	CG10640 gene product from transcript CG10640-RA	0.011
fend	forked end	0.011
PIP5K59B	CG3682 gene product from transcript CG3682-RE	0.010
CG6479	CG6479 gene product from transcript CG6479-RB	0.010
Dsp1	Dorsal switch protein 1	0.010
mirr	mirror	0.010
B-H1	BarH1	0.010
kirre	kin of irre	0.010	Mouse
CG14722	CG14722 gene product from transcript CG14722-RA	0.010
rg	rugose	0.010
kel	kelch	0.010
Ufd1-like	Ubiquitin fusion-degradation 1-like	0.010
brk	brinker	0.010
mrt	martik	0.010
2mit	CG42573 gene product from transcript CG42573-RA	0.010
pbl	pebble	0.010
CG3342	CG3342 gene product from transcript CG3342-RA	0.010
CG5126	CG5126 gene product from transcript CG5126-RA	0.010