IMP: Integrative Multi-species Prediction

Drosophila melanogaster

26 genes annotated in fly

sarcomere organization

The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.

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In addition to gene-name show these genes:

Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "sarcomere organization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "sarcomere organization" (in gray)

Name	Description	Probability	Func Analog Organism
Mhc	Myosin heavy chain	1.000
sls	sallimus	1.000
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.997	Mouse
Actn	alpha actinin	0.997
Mlc2	Myosin light chain 2	0.993
Tm2	Tropomyosin 2	0.989	Human
up	upheld	0.988
Act88F	Actin 88F	0.988
wupA	wings up A	0.969
Zasp66	Z band alternatively spliced PDZ-motif protein 66	0.949
fln	flightin	0.929
Prm	Paramyosin	0.915
tmod	tropomodulin	0.858	Worm
sals	sarcomere length short	0.858
CG11299	CG11299 gene product from transcript CG11299-RA	0.816
tw	Protein O-mannosyltransferase 2	0.734
flw	flapwing	0.705
sr	stripe	0.494
Mical	Molecule interacting with CasL	0.491
DAAM	Dishevelled Associated Activator of Morphogenesis	0.439
Rya-r44F	Ryanodine receptor 44F	0.395
Cf2	Chorion factor 2	0.369
fliI	flightless I	0.360
mys	myospheroid	0.344	Mouse
Dcr-2	Dicer-2	0.336
coro	CG9446 gene product from transcript CG9446-RC	0.322
TER94	CG2331 gene product from transcript CG2331-RA	0.314
Cul-3	Cullin-3	0.265
Gpdh	Glycerol 3 phosphate dehydrogenase	0.243
Mlp84B	Muscle LIM protein at 84B	0.223
if	inflated	0.220
pigs	pickled eggs	0.187
Amph	Amphiphysin	0.169
mbl	muscleblind	0.168
stmA	stambha A	0.159
Scgdelta	Sarcoglycan delta	0.112
CanB2	Calcineurin B2	0.109
eIF-4E	Eukaryotic initiation factor 4E	0.094
Su(z)12	CG8013 gene product from transcript CG8013-RA	0.092
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.090
vg	vestigial	0.089
RhoGEF2	CG9635 gene product from transcript CG9635-RF	0.084
Tsp	Thrombospondin	0.083
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.082
cora	coracle	0.081
rt	rotated abdomen	0.079
sns	sticks and stones	0.078
comt	comatose	0.078
endoA	endophilin A	0.076
Gpo-1	Glycerophosphate oxidase-1	0.075
CG9297	CG9297 gene product from transcript CG9297-RB	0.073
mub	mushroom-body expressed	0.071
e(y)3	enhancer of yellow 3	0.068
how	held out wings	0.068
VAChT	CG32848 gene product from transcript CG32848-RA	0.065
zip	zipper	0.062
Tom34	Translocase of outer membrane 34	0.061
BicD	Bicaudal D	0.059
htl	heartless	0.059
stnA	stoned A	0.057
Vrp1	Verprolin 1	0.056
Cdc42	CG12530 gene product from transcript CG12530-RA	0.054
crm	cramped	0.050
nau	nautilus	0.049
Act57B	Actin 57B	0.048
Mef2	Myocyte enhancer factor 2	0.047	Mouse
fra	frazzled	0.045
klar	klarsicht	0.044
ewg	erect wing	0.043
cno	canoe	0.043
LamC	Lamin C	0.041
Grip	Glutamate receptor binding protein	0.039
Mlc1	Myosin alkali light chain 1	0.038
Mp20	Muscle protein 20	0.038
sha	shavenoid	0.037
CG32528	CG32528 gene product from transcript CG32528-RA	0.037
Unc-89	CG33519 gene product from transcript CG33519-RC	0.037
Lasp	CG3849 gene product from transcript CG3849-RB	0.036
trc	tricornered	0.035
Unc-76	CG3981 gene product from transcript CG3981-RB	0.034
pan	pangolin	0.034
dco	discs overgrown	0.033
twi	twist	0.033
wb	wing blister	0.031
gcl	germ cell-less	0.031
kon	kon-tiki	0.031
tra	transformer	0.030
zfh1	Zn finger homeodomain 1	0.030
slou	slouch	0.029
na	narrow abdomen	0.029
unc-13	CG2999 gene product from transcript CG2999-RA	0.029
blow	blown fuse	0.028
shg	shotgun	0.028
Act5C	Actin 5C	0.028
Cg25C	Collagen type IV	0.028
CG13424	CG13424 gene product from transcript CG13424-RA	0.028
wech	CG42396 gene product from transcript CG42396-RC	0.027
Lrt	Leucine-rich tendon-specific protein	0.026
wcd	wicked	0.026
Pkn	Protein kinase related to protein kinase N	0.025
CG15365	CG15365 gene product from transcript CG15365-RA	0.024
ck	crinkled	0.024
TpnC73F	Troponin C at 73F	0.023
Taf4	TBP-associated factor 4	0.023
CG8578	CG8578 gene product from transcript CG8578-RA	0.023
Oli	Olig family	0.023
kn	knot	0.022
Vang	Van Gogh	0.022
mib2	mind bomb 2	0.022
shakB	shaking B	0.022
CG5177	CG5177 gene product from transcript CG5177-RA	0.022
JIL-1	CG6297 gene product from transcript CG6297-RA	0.022
hfw	halfway	0.022
Pak3	CG14895 gene product from transcript CG14895-RA	0.022
Adf1	Adh transcription factor 1	0.022
Sox102F	CG11153 gene product from transcript CG11153-RB	0.021
stj	straightjacket	0.021
Kmn1	kinetochore Mis12-Ndc80 network component 1	0.021
Hr38	Hormone receptor-like in 38	0.021
foxo	forkhead box, sub-group O	0.020
Frq1	Frequenin 1	0.020
CG3371	CG3371 gene product from transcript CG3371-RA	0.020
rap	retina aberrant in pattern	0.019
eg	eagle	0.019
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.019
mp	multiplexin	0.019
Ddc	Dopa decarboxylase	0.019
CG30069	CG30069 gene product from transcript CG30069-RA	0.019
wdb	widerborst	0.019
spas	spastin	0.018
bru-3	bruno-3	0.018
elav	embryonic lethal abnormal vision	0.018
slow	slowdown	0.018
rumi	CG31152 gene product from transcript CG31152-RA	0.017
aop	anterior open	0.017
tin	tinman	0.017
mas	masquerade	0.017
CG7145	CG7145 gene product from transcript CG7145-RD	0.017
ogre	optic ganglion reduced	0.017
lbe	ladybird early	0.016
stet	stem cell tumor	0.016
Npc1a	Niemann-Pick type C-1a	0.016
rho-5	rhomboid-5	0.016
Ctr1A	Copper transporter 1A	0.015
sn	singed	0.015
HtrA2	CG8464 gene product from transcript CG8464-RA	0.015
pcs	parcas	0.015
cdi	center divider	0.015
KaiRIA	CG18039 gene product from transcript CG18039-RA	0.015
Pink1	PTEN-induced putative kinase 1	0.015
rost	rolling stone	0.014
vnd	ventral nervous system defective	0.014
CG1674	CG1674 gene product from transcript CG1674-RB	0.014
Sdc	Syndecan	0.014
pr-set7	CG3307 gene product from transcript CG3307-RC	0.014
scb	scab	0.014
AGO1	Argonaute-1	0.014
hig	hikaru genki	0.014
CG12026	CG12026 gene product from transcript CG12026-RB	0.014
kst	karst	0.013
sing	singles bar	0.013
CanA-14F	Calcineurin A at 14F	0.013
zen	zerknullt	0.013
nct	nicastrin	0.013
Thor	CG8846 gene product from transcript CG8846-RA	0.013
wun2	wunen-2	0.013
Mpk2	CG5475 gene product from transcript CG5475-RB	0.013
simj	simjang	0.013
Scm	Sex comb on midleg	0.013
ari-2	ariadne 2	0.013
rno	rhinoceros	0.013
betaTub60D	beta-Tubulin at 60D	0.013
Mmp2	Matrix metalloproteinase 2	0.013
Mf	Myofilin	0.012
nvy	nervy	0.012
TpnC47D	Troponin C at 47D	0.012
numb	CG3779 gene product from transcript CG3779-RB	0.012
rho	rhomboid	0.012
byn	brachyenteron	0.012
tkv	thickveins	0.012
ed	echinoid	0.012
Fas1	Fasciclin 1	0.012
msn	misshapen	0.012
CG5376	CG5376 gene product from transcript CG5376-RA	0.012
gish	gilgamesh	0.012
retn	retained	0.012
CG3244	CG3244 gene product from transcript CG3244-RA	0.012
ird5	immune response deficient 5	0.012
WASp	CG1520 gene product from transcript CG1520-RA	0.012
Krn	Keren	0.012
ro	rough	0.012
Mcr	Macroglobulin complement-related	0.012
Rac1	CG2248 gene product from transcript CG2248-RA	0.012
pdfr	PDF receptor	0.012
Spt6	CG12225 gene product from transcript CG12225-RA	0.011
east	enhanced adult sensory threshold	0.011
Vps35	Vacuolar protein sorting 35	0.011
l(1)G0095	lethal (1) G0095	0.011
dwg	deformed wings	0.011
Hand	CG18144 gene product from transcript CG18144-RA	0.011
kirre	kin of irre	0.011
Dms	Dromyosuppressin	0.011
CG10631	CG10631 gene product from transcript CG10631-RA	0.011
fne	found in neurons	0.011
fau	CG6544 gene product from transcript CG6544-RA	0.011
Cad87A	CG6977 gene product from transcript CG6977-RA	0.011
l(2)efl	lethal (2) essential for life	0.011
Met	Methoprene-tolerant	0.011
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.011
fend	forked end	0.011
Cyp303a1	CG4163 gene product from transcript CG4163-RA	0.011
TpnC41C	Troponin C at 41C	0.011
Bap55	Brahma associated protein 55kD	0.011
repo	reversed polarity	0.011
l(2)k16918	lethal (2) k16918	0.011
kuz	kuzbanian	0.011
Df31	Decondensation factor 31	0.010
oaf	out at first	0.010
CG7565	CG7565 gene product from transcript CG7565-RA	0.010
Rala	Ras-related protein	0.010
unc79	CG5237 gene product from transcript CG5237-RB	0.010
Wnt5	Wnt oncogene analog 5	0.010
mtg	mind the gap	0.010
Nop60B	Nucleolar protein at 60B	0.010
fdl	fused lobes	0.010
Gem3	Gemin3	0.010
sd	scalloped	0.010
CG12972	CG12972 gene product from transcript CG12972-RA	0.010
eve	even skipped	0.010