IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 genes annotated in fly

bone development disease

DOID:0080006

A bone disease that results in abnormal growth and development located in bone or located in cartilage.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "bone development disease" (in gray)

Name	Description	Probability	Func Analog Organism
E(spl)	Enhancer of split	0.974	Human
HLHm7	E(spl) region transcript m7	0.959	Human
HLHmdelta	E(spl) region transcript mdelta	0.935	Human
Egfr	Epidermal growth factor receptor	0.869
HLHmbeta	E(spl) region transcript mbeta	0.831	Human
HLHm5	E(spl) region transcript m5	0.823	Human
malpha	E(spl) region transcript malpha	0.740
HLHmgamma	E(spl) region transcript mgamma	0.640	Human
HLHm3	E(spl) region transcript m3	0.569	Human
m4	E(spl) region transcript m4	0.517
en	engrailed	0.516
m2	E(spl) region transcript m2	0.476
hh	hedgehog	0.421
ac	achaete	0.413
bnl	branchless	0.376
Tom	Twin of m4	0.295
stumps	CG31317 gene product from transcript CG31317-RC	0.238
tin	tinman	0.224
sc	scute	0.136
Ras85D	Ras oncogene at 85D	0.128
dpp	decapentaplegic	0.118	Human
if	inflated	0.115
brm	brahma	0.105
N	Notch	0.098
inv	invected	0.089
sr	stripe	0.077
l(2)gl	lethal (2) giant larvae	0.077
CG12424	CG12424 gene product from transcript CG12424-RC	0.071
Cp190	Centrosomal protein 190kD	0.069
eIF-4E	Eukaryotic initiation factor 4E	0.067
wg	wingless	0.058	Human
slp1	sloppy paired 1	0.058
skl	sickle	0.057
Tor	Target of rapamycin	0.052
eya	eyes absent	0.050
tap	target of Poxn	0.048
Dref	DNA replication-related element factor	0.043
Dl	Delta	0.043	Human
sog	short gastrulation	0.038
nkd	naked cuticle	0.038
hep	hemipterous	0.038
arm	armadillo	0.038
Su(var)205	Suppressor of variegation 205	0.038
noc	no ocelli	0.036
BobA	Brother of Bearded A	0.033
sca	scabrous	0.032
Aats-ile	Isoleucyl-tRNA synthetase	0.031
Dad	Daughters against dpp	0.030
Wnt2	Wnt oncogene analog 2	0.030
Trh	Tryptophan hydroxylase	0.029
CG15459	CG15459 gene product from transcript CG15459-RA	0.028
gsb	gooseberry	0.028
CG8965	CG8965 gene product from transcript CG8965-RA	0.027
ci	cubitus interruptus	0.027	Human
Rbp9	RNA-binding protein 9	0.026
phl	pole hole	0.026
Aos1	CG12276 gene product from transcript CG12276-RA	0.025
zfh1	Zn finger homeodomain 1	0.025
Mrtf	Myocardin-related transcription factor	0.024
CG17190	CG17190 gene product from transcript CG17190-RA	0.023
Tif-IA	CG3278 gene product from transcript CG3278-RA	0.023
gbb	glass bottom boat	0.023
nrv2	nervana 2	0.022
Abd-B	Abdominal B	0.022
H	Hairless	0.020
cwo	clockwork orange	0.020
btl	breathless	0.020	Human
argos	CG4531 gene product from transcript CG4531-RA	0.020
htl	heartless	0.020	Human
p130CAS	CG1212 gene product from transcript CG1212-RA	0.020
CG32813	CG32813 gene product from transcript CG32813-RE	0.019
gt	giant	0.019
CG2182	CG2182 gene product from transcript CG2182-RA	0.019
kni	knirps	0.018
grn	grain	0.018
Rat1	CG10354 gene product from transcript CG10354-RA	0.018
Trl	Trithorax-like	0.018
CG11138	CG11138 gene product from transcript CG11138-RC	0.017
ato	atonal	0.017
Hs6st	Heparan sulfate 6-O-sulfotransferase	0.017
CG5899	CG5899 gene product from transcript CG5899-RA	0.017
Rpb5	CG11979 gene product from transcript CG11979-RA	0.016
stg	string	0.016
ems	empty spiracles	0.016
twi	twist	0.016	Human
Tl	Toll	0.016
zen	zerknullt	0.016
CG9797	CG9797 gene product from transcript CG9797-RA	0.016
tld	tolloid	0.016	Human
emc	extra macrochaetae	0.016
ase	asense	0.016
nrv1	nervana 1	0.016
caup	caupolican	0.015
gcm	glial cells missing	0.015
dlg1	discs large 1	0.015
sax	saxophone	0.015
lbk	lambik	0.015
CG1344	CG1344 gene product from transcript CG1344-RA	0.015
Jupiter	CG31363 gene product from transcript CG31363-RD	0.015
pzg	putzig	0.015
CG4769	CG4769 gene product from transcript CG4769-RA	0.015
cv	crossveinless	0.014
Fatp	Fatty acid (long chain) transport protein	0.014
lbl	ladybird late	0.014
CG15365	CG15365 gene product from transcript CG15365-RA	0.014
Paf-AHalpha	Platelet-activating factor acetylhydrolase alpha	0.014
cg	combgap	0.014
CG15580	CG15580 gene product from transcript CG15580-RC	0.014
cta	concertina	0.014
Crk	CG1587 gene product from transcript CG1587-RC	0.014
pros	prospero	0.014
CG42353	CG42353 gene product from transcript CG42353-RA	0.014
slp2	sloppy paired 2	0.014
zfh2	Zn finger homeodomain 2	0.014
neur	neuralized	0.014
slou	slouch	0.014
bib	big brain	0.014
odd	odd skipped	0.013
lama	lamina ancestor	0.013
rib	ribbon	0.013
cals	calsyntenin-1	0.013
puc	puckered	0.013
asp	abnormal spindle	0.013
kel	kelch	0.013
CG3714	CG3714 gene product from transcript CG3714-RC	0.013
l(3)neo18	lethal (3) neo18	0.013
rpr	reaper	0.013
Set	CG4299 gene product from transcript CG4299-RA	0.013
CG6776	CG6776 gene product from transcript CG6776-RA	0.013
CG31644	CG31644 gene product from transcript CG31644-RA	0.013
18w	18 wheeler	0.013
m6	E(spl) region transcript m6	0.012
ko	knockout	0.012
CG3192	CG3192 gene product from transcript CG3192-RA	0.012
rtv	retroactive	0.012
Him	Holes in muscle	0.012
brn	brainiac	0.012
hth	homothorax	0.012
CG6051	CG6051 gene product from transcript CG6051-RB	0.012
edl	ETS-domain lacking	0.012
srw	shrew	0.012
Caf1	Chromatin assembly factor 1 subunit	0.012
mam	mastermind	0.012
amos	absent MD neurons and olfactory sensilla	0.011
stl	stall	0.011
Prosbeta5R	Proteasome beta5R subunit	0.011
CG11148	CG11148 gene product from transcript CG11148-RD	0.011
uzip	unzipped	0.011
pyr	pyramus	0.011
resilin	CG15920 gene product from transcript CG15920-RA	0.011
Arf102F	ADP ribosylation factor 102F	0.011
kon	kon-tiki	0.011
CG7028	CG7028 gene product from transcript CG7028-RA	0.011
MED22	Mediator complex subunit 22	0.011
bin	biniou	0.011
Osi6	Osiris 6	0.011
Ubc-E2H	CG2257 gene product from transcript CG2257-RA	0.011
CycA	Cyclin A	0.011
RnpS1	RNA-binding protein S1	0.011
fzy	fizzy	0.011
pan	pangolin	0.011
yu	CG3249 gene product from transcript CG3249-RA	0.011
geminin	CG3183 gene product from transcript CG3183-RA	0.011
Nup98	Nucleoporin 98	0.011
wun	wunen	0.010
scw	screw	0.010
GATAe	CG10278 gene product from transcript CG10278-RB	0.010
wb	wing blister	0.010
wor	worniu	0.010
ana	anachronism	0.010
srp	serpent	0.010
Gsc	Goosecoid	0.010
CG10933	CG10933 gene product from transcript CG10933-RA	0.010
dl	dorsal	0.010
CG13404	CG13404 gene product from transcript CG13404-RB	0.010
vig2	CG11844 gene product from transcript CG11844-RB	0.010
CG6656	CG6656 gene product from transcript CG6656-RA	0.010
Baldspot	CG3971 gene product from transcript CG3971-RA	0.010