IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 genes annotated in fly

myopathy

DOID:423

A muscular disease in which the muscle fibers do not function resulting in muscular weakness.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in flyInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "myopathy" (in gray)

Name	Description	Probability	Func Analog Organism
wupA	wings up A	0.760
Mhc	Myosin heavy chain	0.690
Actn	alpha actinin	0.527
N	Notch	0.398
Tm2	Tropomyosin 2	0.315	Human
up	upheld	0.304	Human
sls	sallimus	0.275
Ras85D	Ras oncogene at 85D	0.232
Prm	Paramyosin	0.194
Mlc1	Myosin alkali light chain 1	0.149
Lam	Lamin	0.141	Human
Dl	Delta	0.140
Mlc2	Myosin light chain 2	0.123
arm	armadillo	0.113	Human
Act88F	Actin 88F	0.111
Sh3beta	CG8582 gene product from transcript CG8582-RD	0.111
Rab11	Rab-protein 11	0.097
Egfr	Epidermal growth factor receptor	0.086
phl	pole hole	0.083	Human
Mlp84B	Muscle LIM protein at 84B	0.079
Hrb27C	Heterogeneous nuclear ribonucleoprotein at 27C	0.068
Zasp66	Z band alternatively spliced PDZ-motif protein 66	0.067
Hsp23	Heat shock protein 23	0.067
Taf1	TBP-associated factor 1	0.061
Act57B	Actin 57B	0.058
Mf	Myofilin	0.057
gbb	glass bottom boat	0.057
chic	chickadee	0.056
Cdc42	CG12530 gene product from transcript CG12530-RA	0.053
Hsp68	Heat shock protein 68	0.051
Trxr-1	Thioredoxin reductase-1	0.051
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.044	Human
spi	spitz	0.043
sqh	spaghetti squash	0.042
fln	flightin	0.041
CG5177	CG5177 gene product from transcript CG5177-RA	0.041
Df31	Decondensation factor 31	0.041
if	inflated	0.040
aop	anterior open	0.037
wg	wingless	0.037
eya	eyes absent	0.036	Human
Mp20	Muscle protein 20	0.035
Moe	Moesin	0.035
Cg25C	Collagen type IV	0.034
Hsp27	Heat shock protein 27	0.033
CAP	CG18408 gene product from transcript CG18408-RI	0.033
glo	glorund	0.032
CG9297	CG9297 gene product from transcript CG9297-RB	0.030
Hrb87F	Heterogeneous nuclear ribonucleoprotein at 87F	0.029
slou	slouch	0.029
Pten	CG5671 gene product from transcript CG5671-RB	0.027
Dlic	Dynein light intermediate chain	0.026
Snx6	CG8282 gene product from transcript CG8282-RA	0.025
sax	saxophone	0.025
Gpo-1	Glycerophosphate oxidase-1	0.025
Bap	Beta Adaptin	0.025
ci	cubitus interruptus	0.024
stv	starvin	0.023
cora	coracle	0.023
Pcaf	CG4107 gene product from transcript CG4107-RA	0.023
Tsp	Thrombospondin	0.022
nej	nejire	0.022
bt	bent	0.022
alt	aluminum tubes	0.022
sqd	squid	0.021	Human
Dsor1	Downstream of raf1	0.021
kon	kon-tiki	0.021
LanB2	Laminin B2	0.021
H	Hairless	0.021
Arf79F	ADP ribosylation factor 79F	0.020
EcR	Ecdysone receptor	0.020
rig	rigor mortis	0.019
GstS1	Glutathione S transferase S1	0.019
Rya-r44F	Ryanodine receptor 44F	0.019	Human
coro	CG9446 gene product from transcript CG9446-RC	0.019
gl	glass	0.018
Vmat	Vesicular monoamine transporter	0.018
Sdc	Syndecan	0.018
Act87E	Actin 87E	0.018
rols	rolling pebbles	0.018
Ddc	Dopa decarboxylase	0.017
Hem	HEM-protein	0.017
Pax	Paxillin	0.017
tsr	twinstar	0.017
crb	crumbs	0.017
cals	calsyntenin-1	0.017
smt3	CG4494 gene product from transcript CG4494-RA	0.017
mbl	muscleblind	0.016
sgg	shaggy	0.016
sqz	squeeze	0.016
Chd64	CG14996 gene product from transcript CG14996-RB	0.016
Rab1	Rab-protein 1	0.016
CG8443	CG8443 gene product from transcript CG8443-RA	0.016
CG9090	CG9090 gene product from transcript CG9090-RA	0.016
baz	bazooka	0.016
betaTub60D	beta-Tubulin at 60D	0.016
dpp	decapentaplegic	0.016
sr	stripe	0.016
Psn	Presenilin	0.016	Human
CG10638	CG10638 gene product from transcript CG10638-RA	0.016
CG1902	CG1902 gene product from transcript CG1902-RA	0.016
Ras64B	Ras oncogene at 64B	0.016
akirin	CG8580 gene product from transcript CG8580-RD	0.015
emc	extra macrochaetae	0.015
cher	cheerio	0.015	Human
ctp	cut up	0.015
hpo	hippo	0.015
Gpdh	Glycerol 3 phosphate dehydrogenase	0.015
shot	short stop	0.015	Human
tkv	thickveins	0.015
insc	inscuteable	0.015
Mical	Molecule interacting with CasL	0.015
CG8709	CG8709 gene product from transcript CG8709-RK	0.015
Tom34	Translocase of outer membrane 34	0.014
dsh	dishevelled	0.014
tral	trailer hitch	0.014
vkg	viking	0.014
blow	blown fuse	0.014
BicD	Bicaudal D	0.014
HspB8	CG14207 gene product from transcript CG14207-RB	0.014
egg	eggless	0.014
Argk	Arginine kinase	0.014
CG12007	CG12007 gene product from transcript CG12007-RA	0.014
abba	another B-box affiliate	0.014
CG17737	CG17737 gene product from transcript CG17737-RA	0.013
put	punt	0.013
TpnC47D	Troponin C at 47D	0.013
tmod	tropomodulin	0.013
e(y)3	enhancer of yellow 3	0.013
opa1-like	optic atrophy 1-like	0.012
dap	dacapo	0.012
Act79B	Actin 79B	0.012
Aos1	CG12276 gene product from transcript CG12276-RA	0.012
Neurochondrin	CG2330 gene product from transcript CG2330-RA	0.012
noc	no ocelli	0.012
CG32685	CG32685 gene product from transcript CG32685-RC	0.012
NetB	Netrin-B	0.012
CG5023	CG5023 gene product from transcript CG5023-RA	0.012
ptc	patched	0.012
stj	straightjacket	0.012
Rho1	CG8416 gene product from transcript CG8416-RB	0.012
Cortactin	CG3637 gene product from transcript CG3637-RA	0.012
trio	CG18214 gene product from transcript CG18214-RA	0.012
OstStt3	Oligosaccharyl transferase 3	0.012
Mtch	Mitochondrial carrier homolog 1	0.012
Dcr-2	Dicer-2	0.012
twi	twist	0.012
CG11299	CG11299 gene product from transcript CG11299-RA	0.012
Hsp26	Heat shock protein 26	0.012	Human
TER94	CG2331 gene product from transcript CG2331-RA	0.012
CSN5	COP9 complex homolog subunit 5	0.012
Chc	Clathrin heavy chain	0.012
CG5854	CG5854 gene product from transcript CG5854-RA	0.011
bbc	bb in a boxcar	0.011
Hop	Hsp70/Hsp90 organizing protein homolog	0.011
so	sine oculis	0.011
CG32016	CG32016 gene product from transcript CG32016-RB	0.011
LamC	Lamin C	0.011	Human
TpnC73F	Troponin C at 73F	0.011
ttk	tramtrack	0.011
Act42A	Actin 42A	0.011
Thor	CG8846 gene product from transcript CG8846-RA	0.011
Adam	CG12131 gene product from transcript CG12131-RA	0.011
pigs	pickled eggs	0.011
sbr	small bristles	0.011
uex	unextended	0.011
Tor	Target of rapamycin	0.011
CG13887	CG13887 gene product from transcript CG13887-RC	0.011
Sop2	Suppressor of profilin 2	0.011
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.011
Myo31DF	Myosin 31DF	0.011
SH3PX1	CG6757 gene product from transcript CG6757-RA	0.011
CG11006	CG11006 gene product from transcript CG11006-RC	0.011
Gp150	CG5820 gene product from transcript CG5820-RA	0.011
wb	wing blister	0.011
by	blistery	0.010
ari-1	ariadne	0.010
CG10916	CG10916 gene product from transcript CG10916-RA	0.010
Rac1	CG2248 gene product from transcript CG2248-RA	0.010
Rdl	Resistant to dieldrin	0.010
htl	heartless	0.010
Pen	Pendulin	0.010
Mef2	Myocyte enhancer factor 2	0.010
Pdi	Protein disulfide isomerase	0.010
bdg	bedraggled	0.010
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.010
pb	proboscipedia	0.010
ATP7	CG1886 gene product from transcript CG1886-RB	0.010
RhoL	rho-like	0.010
slpr	slipper	0.010
Atf6	CG3136 gene product from transcript CG3136-RA	0.010
CG9338	CG9338 gene product from transcript CG9338-RA	0.010
lmd	lame duck	0.010
sec5	CG8843 gene product from transcript CG8843-RA	0.010
RhoGDI	CG7823 gene product from transcript CG7823-RA	0.010