IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 genes annotated in fly

muscle tissue disease

DOID:66

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "muscle tissue disease" (in gray)

Name	Description	Probability	Func Analog Organism
wupA	wings up A	0.760
Mhc	Myosin heavy chain	0.690
Actn	alpha actinin	0.527
N	Notch	0.398
sls	sallimus	0.328
Tm2	Tropomyosin 2	0.315	Human
up	upheld	0.304	Human
sqh	spaghetti squash	0.239
Ras85D	Ras oncogene at 85D	0.232
Prm	Paramyosin	0.194
Lam	Lamin	0.165	Human
Mlc1	Myosin alkali light chain 1	0.149
Dl	Delta	0.140
Mlc2	Myosin light chain 2	0.123
arm	armadillo	0.113	Human
Act88F	Actin 88F	0.111
Sh3beta	CG8582 gene product from transcript CG8582-RD	0.111
chic	chickadee	0.099
Hsp23	Heat shock protein 23	0.098
Rab11	Rab-protein 11	0.097
Cdc42	CG12530 gene product from transcript CG12530-RA	0.090
Egfr	Epidermal growth factor receptor	0.086
phl	pole hole	0.083	Human
Mlp84B	Muscle LIM protein at 84B	0.079
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.070	Human
Hsp27	Heat shock protein 27	0.068
Hrb27C	Heterogeneous nuclear ribonucleoprotein at 27C	0.068
Zasp66	Z band alternatively spliced PDZ-motif protein 66	0.067
spi	spitz	0.061
Taf1	TBP-associated factor 1	0.061
Act57B	Actin 57B	0.058
Mf	Myofilin	0.057
gbb	glass bottom boat	0.057
if	inflated	0.057
Hsp68	Heat shock protein 68	0.051
Trxr-1	Thioredoxin reductase-1	0.051
cora	coracle	0.047
Rya-r44F	Ryanodine receptor 44F	0.046	Human
betaTub60D	beta-Tubulin at 60D	0.045
CAP	CG18408 gene product from transcript CG18408-RI	0.044
sr	stripe	0.041
fln	flightin	0.041
CG5177	CG5177 gene product from transcript CG5177-RA	0.041
Cg25C	Collagen type IV	0.041
Df31	Decondensation factor 31	0.041
kon	kon-tiki	0.040
Snx6	CG8282 gene product from transcript CG8282-RA	0.040
Pabp2	CG2163 gene product from transcript CG2163-RA	0.038	Human
aop	anterior open	0.037
wg	wingless	0.037
eya	eyes absent	0.036	Human
Mp20	Muscle protein 20	0.035
Moe	Moesin	0.035
Chc	Clathrin heavy chain	0.035
LanB1	CG7123 gene product from transcript CG7123-RA	0.034
rols	rolling pebbles	0.034
Psn	Presenilin	0.034	Human
glo	glorund	0.032
SRPK	CG8174 gene product from transcript CG8174-RA	0.032
stv	starvin	0.031
CG9297	CG9297 gene product from transcript CG9297-RB	0.030
TER94	CG2331 gene product from transcript CG2331-RA	0.030
RhoGDI	CG7823 gene product from transcript CG7823-RA	0.030
Hrb87F	Heterogeneous nuclear ribonucleoprotein at 87F	0.029
slou	slouch	0.029
nos	nanos	0.028
Pten	CG5671 gene product from transcript CG5671-RB	0.027
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.026
Dlic	Dynein light intermediate chain	0.026
sax	saxophone	0.025
Gpo-1	Glycerophosphate oxidase-1	0.025
Bap	Beta Adaptin	0.025
atl	atlastin	0.025
Tom34	Translocase of outer membrane 34	0.024
ci	cubitus interruptus	0.024
CG2852	CG2852 gene product from transcript CG2852-RA	0.023
Vmat	Vesicular monoamine transporter	0.023
CG8709	CG8709 gene product from transcript CG8709-RK	0.023
vkg	viking	0.023
Pcaf	CG4107 gene product from transcript CG4107-RA	0.023
flw	flapwing	0.023
Tsp	Thrombospondin	0.022
nej	nejire	0.022
bt	bent	0.022
sesB	stress-sensitive B	0.022
Syb	Synaptobrevin	0.022
alt	aluminum tubes	0.022
Tig	Tiggrin	0.022
Ddc	Dopa decarboxylase	0.022
Chd64	CG14996 gene product from transcript CG14996-RB	0.021
pain	painless	0.021
sqd	squid	0.021	Human
BicD	Bicaudal D	0.021
Thor	CG8846 gene product from transcript CG8846-RA	0.021
Dsor1	Downstream of raf1	0.021
LanB2	Laminin B2	0.021
H	Hairless	0.021
Arf79F	ADP ribosylation factor 79F	0.020
EcR	Ecdysone receptor	0.020
shrb	shrub	0.020
LamC	Lamin C	0.020	Human
Mef2	Myocyte enhancer factor 2	0.020
rig	rigor mortis	0.019
GstS1	Glutathione S transferase S1	0.019
CG12007	CG12007 gene product from transcript CG12007-RA	0.019
coro	CG9446 gene product from transcript CG9446-RC	0.019
TH1	CG9984 gene product from transcript CG9984-RA	0.018
CG4038	CG4038 gene product from transcript CG4038-RA	0.018
gl	glass	0.018
eEF1delta	CG4912 gene product from transcript CG4912-RB	0.018
stj	straightjacket	0.018
rhea	CG6831 gene product from transcript CG6831-RA	0.018
Sdc	Syndecan	0.018
Act87E	Actin 87E	0.018
Adam	CG12131 gene product from transcript CG12131-RA	0.017
Nacalpha	Nascent polypeptide associated complex protein alpha subunit	0.017
Hem	HEM-protein	0.017
Pax	Paxillin	0.017
tsr	twinstar	0.017
crb	crumbs	0.017
loj	logjam	0.017
cals	calsyntenin-1	0.017
Eip75B	Ecdysone-induced protein 75B	0.017
smt3	CG4494 gene product from transcript CG4494-RA	0.017
mbl	muscleblind	0.016
sgg	shaggy	0.016
so	sine oculis	0.016
sqz	squeeze	0.016
Rab1	Rab-protein 1	0.016
CG8443	CG8443 gene product from transcript CG8443-RA	0.016
CG9090	CG9090 gene product from transcript CG9090-RA	0.016
Sos	Son of sevenless	0.016
baz	bazooka	0.016
l(2)efl	lethal (2) essential for life	0.016
dpp	decapentaplegic	0.016
blow	blown fuse	0.016
CG10638	CG10638 gene product from transcript CG10638-RA	0.016
CG1902	CG1902 gene product from transcript CG1902-RA	0.016
Cat	Catalase	0.016
nmo	nemo	0.016
Ras64B	Ras oncogene at 64B	0.016
CG7830	CG7830 gene product from transcript CG7830-RA	0.015
akirin	CG8580 gene product from transcript CG8580-RD	0.015
emc	extra macrochaetae	0.015
cher	cheerio	0.015	Human
ctp	cut up	0.015
hpo	hippo	0.015
Gpdh	Glycerol 3 phosphate dehydrogenase	0.015
shot	short stop	0.015	Human
tkv	thickveins	0.015
insc	inscuteable	0.015
Mical	Molecule interacting with CasL	0.015
dsh	dishevelled	0.014
tral	trailer hitch	0.014
CG9894	CG9894 gene product from transcript CG9894-RB	0.014
Act42A	Actin 42A	0.014
daw	dawdle	0.014
HspB8	CG14207 gene product from transcript CG14207-RB	0.014
egg	eggless	0.014
Cf2	Chorion factor 2	0.014
Argk	Arginine kinase	0.014
abba	another B-box affiliate	0.014
CG17737	CG17737 gene product from transcript CG17737-RA	0.013
put	punt	0.013
l(1)G0469	lethal (1) G0469	0.013
unc-13	CG2999 gene product from transcript CG2999-RA	0.013
TpnC47D	Troponin C at 47D	0.013
Traf6	TNF-receptor-associated factor 6	0.013
CG1749	CG1749 gene product from transcript CG1749-RA	0.013
Nlp	Nucleoplasmin	0.013
comt	comatose	0.013
Msr-110	CG10596 gene product from transcript CG10596-RB	0.013
Ca-P60A	Calcium ATPase at 60A	0.013
tmod	tropomodulin	0.013
Gp93	Glycoprotein 93	0.013
e(y)3	enhancer of yellow 3	0.013
Tis11	Tis11 homolog	0.013
CG13887	CG13887 gene product from transcript CG13887-RC	0.013
Papss	PAPS synthetase	0.012
opa1-like	optic atrophy 1-like	0.012
Fkbp13	CG9847 gene product from transcript CG9847-RC	0.012
dap	dacapo	0.012
mys	myospheroid	0.012
Act79B	Actin 79B	0.012
Aos1	CG12276 gene product from transcript CG12276-RA	0.012
poe	purity of essence	0.012
Neurochondrin	CG2330 gene product from transcript CG2330-RA	0.012
noc	no ocelli	0.012
CG32685	CG32685 gene product from transcript CG32685-RC	0.012
CG9186	CG9186 gene product from transcript CG9186-RB	0.012
NetB	Netrin-B	0.012
MED1	Mediator complex subunit 1	0.012
CG5023	CG5023 gene product from transcript CG5023-RA	0.012
pigs	pickled eggs	0.012
ptc	patched	0.012
Oli	Olig family	0.012
stmA	stambha A	0.012
Rho1	CG8416 gene product from transcript CG8416-RB	0.012
rin	rasputin	0.012
Cortactin	CG3637 gene product from transcript CG3637-RA	0.012
Myo31DF	Myosin 31DF	0.012
trio	CG18214 gene product from transcript CG18214-RA	0.012
OstStt3	Oligosaccharyl transferase 3	0.012
Mtch	Mitochondrial carrier homolog 1	0.012
CanB2	Calcineurin B2	0.012
Dcr-2	Dicer-2	0.012
twi	twist	0.012
lmd	lame duck	0.012
CG11299	CG11299 gene product from transcript CG11299-RA	0.012
Hsp26	Heat shock protein 26	0.012	Human
CSN5	COP9 complex homolog subunit 5	0.012
CG5854	CG5854 gene product from transcript CG5854-RA	0.011
bbc	bb in a boxcar	0.011
Hop	Hsp70/Hsp90 organizing protein homolog	0.011
VAChT	CG32848 gene product from transcript CG32848-RA	0.011
cpa	capping protein alpha	0.011
CG32016	CG32016 gene product from transcript CG32016-RB	0.011
Rab6	Rab-protein 6	0.011
miple2	CG18321 gene product from transcript CG18321-RA	0.011
Pdi	Protein disulfide isomerase	0.011
Ctr1A	Copper transporter 1A	0.011
CG10373	CG10373 gene product from transcript CG10373-RA	0.011
CG10576	CG10576 gene product from transcript CG10576-RA	0.011
lolal	lola like	0.011
CG8860	CG8860 gene product from transcript CG8860-RA	0.011
TpnC73F	Troponin C at 73F	0.011
ttk	tramtrack	0.011
rtet	tetracycline resistance	0.011
CG3262	CG3262 gene product from transcript CG3262-RD	0.011
blw	bellwether	0.011
CG5931	CG5931 gene product from transcript CG5931-RA	0.011
Hsp70Ba	Heat-shock-protein-70Ba	0.011
Ance	Angiotensin converting enzyme	0.011
CG10916	CG10916 gene product from transcript CG10916-RA	0.011
sbr	small bristles	0.011
unc-104	CG8566 gene product from transcript CG8566-RB	0.011
uex	unextended	0.011
Tor	Target of rapamycin	0.011
CG7879	CG7879 gene product from transcript CG7879-RB	0.011
Sop2	Suppressor of profilin 2	0.011
SH3PX1	CG6757 gene product from transcript CG6757-RA	0.011
mid	midline	0.011
hig	hikaru genki	0.011
CG17838	CG17838 gene product from transcript CG17838-RA	0.011
Hand	CG18144 gene product from transcript CG18144-RA	0.011
CG11006	CG11006 gene product from transcript CG11006-RC	0.011
Gp150	CG5820 gene product from transcript CG5820-RA	0.011
wb	wing blister	0.011
Manf	Mesencephalic astrocyte-derived neurotrophic factor	0.011
CG8121	CG8121 gene product from transcript CG8121-RA	0.011
by	blistery	0.010
byn	brachyenteron	0.010
ari-1	ariadne	0.010
D1	D1 chromosomal protein	0.010
rut	rutabaga	0.010
dalao	CG7055 gene product from transcript CG7055-RA	0.010
Rac1	CG2248 gene product from transcript CG2248-RA	0.010
Rdl	Resistant to dieldrin	0.010
htl	heartless	0.010
Pen	Pendulin	0.010
TMS1	CG4672 gene product from transcript CG4672-RA	0.010
bdg	bedraggled	0.010
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.010
pb	proboscipedia	0.010
ATP7	CG1886 gene product from transcript CG1886-RB	0.010
RhoL	rho-like	0.010
lbe	ladybird early	0.010
slpr	slipper	0.010
Atf6	CG3136 gene product from transcript CG3136-RA	0.010
CG9338	CG9338 gene product from transcript CG9338-RA	0.010
CG9472	CG9472 gene product from transcript CG9472-RA	0.010
eRF1	eukaryotic release factor 1	0.010
Nrx-1	Neurexin 1	0.010
sec5	CG8843 gene product from transcript CG8843-RA	0.010