IMP: Integrative Multi-species Prediction

Drosophila melanogaster

16 genes annotated in fly

negative regulation of proteasomal ubiquitin dependent protein catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of proteasomal ubiquitin dependent protein catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of proteasomal ubiquitin dependent protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Pp1-87B	Protein phosphatase 1 at 87B	0.208	Yeast
Iswi	Imitation SWI	0.193
CycA	Cyclin A	0.185
fzy	fizzy	0.119	Yeast
brm	brahma	0.117
CSN4	COP9 complex homolog subunit 4	0.108
thr	three rows	0.088
Cap-G	CG34438 gene product from transcript CG34438-RF	0.073
CG4030	CG4030 gene product from transcript CG4030-RA	0.070
mad2	CG17498 gene product from transcript CG17498-RA	0.065
flfl	falafel	0.065
CycB3	Cyclin B3	0.057
Su(var)205	Suppressor of variegation 205	0.055
B52	CG10851 gene product from transcript CG10851-RB	0.055
polo	CG12306 gene product from transcript CG12306-RA	0.055	Human
pim	pimples	0.053
BubR1	Bub1-related kinase	0.050
Nup153	Nucleoporin 153	0.050
CycB	Cyclin B	0.047
rux	roughex	0.046
CSN5	COP9 complex homolog subunit 5	0.045
dup	double parked	0.043
cav	caravaggio	0.041
asl	asterless	0.039
nbs	CG6754 gene product from transcript CG6754-RC	0.037
CG2926	CG2926 gene product from transcript CG2926-RA	0.033
snRNP-U1-70K	small ribonucleoprotein particle U1 subunit 70K	0.033
cdc16	CG6759 gene product from transcript CG6759-RA	0.032
pav	pavarotti	0.031
KP78b	CG17216 gene product from transcript CG17216-RB	0.030
qkr58E-1	quaking related 58E-1	0.027
Su(var)2-10	Suppressor of variegation 2-10	0.026
Rpd3	CG7471 gene product from transcript CG7471-RA	0.025
Cdc37	CG12019 gene product from transcript CG12019-RA	0.025
Ptp69D	Protein tyrosine phosphatase 69D	0.024
hyd	hyperplastic discs	0.023
Df31	Decondensation factor 31	0.023
tld	tolloid	0.023
gsb	gooseberry	0.023
Nup160	Nucleoporin 160	0.022
CG6439	CG6439 gene product from transcript CG6439-RA	0.022
SMC2	CG10212 gene product from transcript CG10212-RA	0.021
mei-P26	CG12218 gene product from transcript CG12218-RA	0.021
MED6	Mediator complex subunit 6	0.020
CG6962	CG6962 gene product from transcript CG6962-RA	0.020
Droj2	DnaJ-like-2	0.019
Cyt-c-d	Cytochrome c distal	0.019
CycJ	Cyclin J	0.019
Kmn1	kinetochore Mis12-Ndc80 network component 1	0.019
CG14213	CG14213 gene product from transcript CG14213-RB	0.019
bam	bag of marbles	0.019
smo	smoothened	0.018
pds5	CG17509 gene product from transcript CG17509-RA	0.018
spn-D	spindle D	0.018
CG8478	CG8478 gene product from transcript CG8478-RD	0.018
hpo	hippo	0.018
Mer	Merlin	0.018
Gef26	CG9491 gene product from transcript CG9491-RB	0.018
gish	gilgamesh	0.018
lab	labial	0.017
fax	failed axon connections	0.017
barr	barren	0.017
CG7288	CG7288 gene product from transcript CG7288-RA	0.017
Taf2	TBP-associated factor 2	0.017
Kap-alpha3	karyopherin alpha3	0.017
Psf2	CG18013 gene product from transcript CG18013-RA	0.016
cnn	centrosomin	0.016
sn	singed	0.016
Bap55	Brahma associated protein 55kD	0.016
CG2617	CG2617 gene product from transcript CG2617-RA	0.016
Sep2	Septin-2	0.016
CycT	Cyclin T	0.016
tefu	telomere fusion	0.016	Human
nej	nejire	0.015
pr-set7	CG3307 gene product from transcript CG3307-RC	0.015
alphaTub67C	alpha-Tubulin at 67C	0.015
Cks30A	Cyclin-dependent kinase subunit 30A	0.014
tum	tumbleweed	0.014
CG9776	CG9776 gene product from transcript CG9776-RA	0.014
CG6540	CG6540 gene product from transcript CG6540-RA	0.014
Ras85D	Ras oncogene at 85D	0.014
TfIIS	RNA polymerase II elongation factor	0.014
borr	borealin-related	0.013
mus301	mutagen-sensitive 301	0.013
Hcf	Host cell factor	0.013
lid	little imaginal discs	0.013
betaTub60D	beta-Tubulin at 60D	0.013
HP1e	CG8120 gene product from transcript CG8120-RA	0.013
CycC	Cyclin C	0.013
Gem2	Gemin2	0.013
CG7145	CG7145 gene product from transcript CG7145-RD	0.013
nxf2	nuclear RNA export factor 2	0.012
dap	dacapo	0.012
CG4771	CG4771 gene product from transcript CG4771-RA	0.012
Sld5	CG14549 gene product from transcript CG14549-RA	0.012
chn	charlatan	0.012
Krn	Keren	0.012
msb1l	CG10364 gene product from transcript CG10364-RA	0.012
cdc2	CG5363 gene product from transcript CG5363-RA	0.012
egg	eggless	0.012
Dsor1	Downstream of raf1	0.012
NiPp1	Nuclear inhibitor of Protein phosphatase 1	0.012
noi	noisette	0.012
PPP4R2r	Protein phosphatase 4 regulatory subunit 2-related protein	0.012
pita	CG3941 gene product from transcript CG3941-RA	0.012
dre4	CG1828 gene product from transcript CG1828-RB	0.012
east	enhanced adult sensory threshold	0.012
mus209	mutagen-sensitive 209	0.012
Sc2	CG10849 gene product from transcript CG10849-RA	0.012
pUf68	poly U binding factor 68kD	0.011
Taf4	TBP-associated factor 4	0.011
th	thread	0.011
Spt3	CG3169 gene product from transcript CG3169-RA	0.011
pall	pallbearer	0.011
oaf	out at first	0.011
D1	D1 chromosomal protein	0.011
CG3679	CG3679 gene product from transcript CG3679-RA	0.011
smt3	CG4494 gene product from transcript CG4494-RA	0.011
slp1	sloppy paired 1	0.011
Sse	Separase	0.011
RpS27A	Ribosomal protein S27A	0.011
Sas-4	CG10061 gene product from transcript CG10061-RA	0.011
Myb	Myb oncogene-like	0.010
Tom40	Translocase of outer membrane 40	0.010
CG17838	CG17838 gene product from transcript CG17838-RA	0.010
CG4751	CG4751 gene product from transcript CG4751-RA	0.010
mus312	mutagen-sensitive 312	0.010
CG4266	CG4266 gene product from transcript CG4266-RA	0.010
run	runt	0.010
MEP-1	CG1244 gene product from transcript CG1244-RG	0.010
gwl	greatwall	0.010