IMP: Integrative Multi-species Prediction

Drosophila melanogaster

43 genes annotated in fly

regulation of protein stability

Any process that affects the structure and integrity of a protein by altering the likelihood of its degradation or aggregation.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of protein stability"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of protein stability" (in gray)

Name	Description	Probability	Func Analog Organism
skpA	CG16983 gene product from transcript CG16983-RD	0.839
CG32581	CG32581 gene product from transcript CG32581-RB	0.171	Mouse
ci	cubitus interruptus	0.141
numb	CG3779 gene product from transcript CG3779-RB	0.140
Rac1	CG2248 gene product from transcript CG2248-RA	0.119
shn	schnurri	0.103
Mad	Mothers against dpp	0.100
pUf68	poly U binding factor 68kD	0.094
lig	lingerer	0.087
Rab11	Rab-protein 11	0.081
arm	armadillo	0.073
CSN3	COP9 complex homolog subunit 3	0.073
Hdac3	Histone deacetylase 3	0.070
Moe	Moesin	0.065
Cdk5	Cyclin-dependent kinase 5	0.061
Pten	CG5671 gene product from transcript CG5671-RB	0.058	Human
CSN4	COP9 complex homolog subunit 4	0.057
His1:CG33813	CG33813 gene product from transcript CG33813-RA	0.056	Human
ida	imaginal discs arrested	0.055
CSN8	COP9 complex homolog subunit 8	0.055
sds22	CG5851 gene product from transcript CG5851-RA	0.054
His1:CG31617	CG31617 gene product from transcript CG31617-RA	0.054	Human
CSN5	COP9 complex homolog subunit 5	0.049
stg	string	0.049
simj	simjang	0.048
His1:CG33849	CG33849 gene product from transcript CG33849-RA	0.047	Human
His1:CG33843	CG33843 gene product from transcript CG33843-RA	0.047	Human
p53	CG33336 gene product from transcript CG33336-RB	0.047
His1:CG33801	CG33801 gene product from transcript CG33801-RA	0.046	Human
jub	Ajuba LIM protein	0.046
His1:CG33840	CG33840 gene product from transcript CG33840-RA	0.045	Human
His1:CG33819	CG33819 gene product from transcript CG33819-RA	0.045	Human
His1:CG33852	CG33852 gene product from transcript CG33852-RA	0.045	Human
His1:CG33825	CG33825 gene product from transcript CG33825-RA	0.045	Human
His1:CG33816	CG33816 gene product from transcript CG33816-RA	0.044	Human
His1:CG33846	CG33846 gene product from transcript CG33846-RA	0.044	Human
His1:CG33855	CG33855 gene product from transcript CG33855-RA	0.044	Human
His1:CG33822	CG33822 gene product from transcript CG33822-RA	0.044	Human
His1:CG33831	CG33831 gene product from transcript CG33831-RA	0.044	Human
His1:CG33828	CG33828 gene product from transcript CG33828-RA	0.044	Human
His1:CG33837	CG33837 gene product from transcript CG33837-RA	0.043	Human
His1:CG33834	CG33834 gene product from transcript CG33834-RA	0.043	Human
His1:CG33804	CG33804 gene product from transcript CG33804-RA	0.043	Human
pasha	partner of drosha	0.042
G-oalpha47A	G protein oalpha 47A	0.042
His1:CG33807	CG33807 gene product from transcript CG33807-RA	0.042	Human
zip	zipper	0.042
His1:CG33861	CG33861 gene product from transcript CG33861-RA	0.042	Human
CycC	Cyclin C	0.041
His1:CG33858	CG33858 gene product from transcript CG33858-RA	0.041	Human
CkIIalpha	Casein kinase II alpha subunit	0.040
His1:CG33810	CG33810 gene product from transcript CG33810-RA	0.040	Human
His1:CG33864	CG33864 gene product from transcript CG33864-RA	0.040	Human
Gie	novel GTPase indispensable for equal segregation of chromosomes	0.038
Ube3a	Ubiquitin protein ligase E3A	0.038
gbb	glass bottom boat	0.036
stj	straightjacket	0.035
Su(z)12	CG8013 gene product from transcript CG8013-RA	0.034
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.034
Cdk4	Cyclin-dependent kinase 4	0.033
Pp2A-29B	Protein phosphatase 2A at 29B	0.032
Ras85D	Ras oncogene at 85D	0.032
sgg	shaggy	0.032
CycD	Cyclin D	0.031
Eps-15	Epidermal growth factor receptor pathway substrate clone 15	0.031
cos	costa	0.030
CG11985	CG11985 gene product from transcript CG11985-RA	0.030
hh	hedgehog	0.029
Trx-2	thioredoxin-2	0.029
heph	hephaestus	0.028
CG9316	CG9316 gene product from transcript CG9316-RA	0.028
Prosbeta3	Proteasome beta3 subunit	0.028
Egfr	Epidermal growth factor receptor	0.028
ovo	CG6824 gene product from transcript CG6824-RE	0.028
alien	CG9556 gene product from transcript CG9556-RB	0.028
mib1	mind bomb 1	0.027
rin	rasputin	0.027
UbcD2	Ubiquitin conjugating enzyme 2	0.027
CG9425	CG9425 gene product from transcript CG9425-RB	0.026
RagA	CG11968 gene product from transcript CG11968-RA	0.026
brm	brahma	0.026
enok	enoki mushroom	0.026
fng	fringe	0.026
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.025	Fly
l(3)01239	lethal (3) 01239	0.025
l(1)10Bb	lethal (1) 10Bb	0.024
l(1)G0007	lethal (1) G0007	0.024
wts	warts	0.024
ds	dachsous	0.023
arr	arrow	0.023
Lam	Lamin	0.023
dlt	discs lost	0.022
Su(H)	Suppressor of Hairless	0.021
ush	u-shaped	0.021
Psn	Presenilin	0.021
neur	neuralized	0.021
Dcr-1	Dicer-1	0.020
dap	dacapo	0.020
Pkn	Protein kinase related to protein kinase N	0.020
CG33680	CG33680 gene product from transcript CG33680-RA	0.020
capt	capulet	0.020
RpII215	RNA polymerase II 215kD subunit	0.020
Smr	Smrter	0.020
CG4221	CG4221 gene product from transcript CG4221-RA	0.020
CG10107	CG10107 gene product from transcript CG10107-RA	0.019
bora	aurora borealis	0.019
slmb	supernumerary limbs	0.019	Human
dpp	decapentaplegic	0.019	Mouse
CG5482	CG5482 gene product from transcript CG5482-RA	0.019
CG8526	CG8526 gene product from transcript CG8526-RA	0.019
CG13085	CG13085 gene product from transcript CG13085-RA	0.018
pex16	peroxin 16	0.018
blot	bloated tubules	0.018
CG7056	CG7056 gene product from transcript CG7056-RA	0.018
lin19	lin-19-like	0.017
Sgt	small glutamine-rich tetratricopeptide containing protein	0.017
Uba1	Ubiquitin activating enzyme 1	0.017
loqs	loquacious	0.017
Fcp1	CG12252 gene product from transcript CG12252-RA	0.017
eya	eyes absent	0.017
Act5C	Actin 5C	0.017
ash2	absent, small, or homeotic discs 2	0.017
CG8368	CG8368 gene product from transcript CG8368-RB	0.017
Arr2	Arrestin 2	0.017
sktl	skittles	0.017
tan	tantalus	0.017
CG5676	CG5676 gene product from transcript CG5676-RA	0.016
smo	smoothened	0.016	Mouse
Mlf	Myelodysplasia/myeloid leukemia factor	0.016
yki	yorkie	0.016
kek5	kekkon5	0.016
beta-Spec	beta Spectrin	0.016
RASSF8	CG5053 gene product from transcript CG5053-RA	0.016
cpx	complexin	0.016
Cpsf73	Cleavage and polyadenylation specificity factor 73	0.016
MED6	Mediator complex subunit 6	0.016
wg	wingless	0.016
ssh	slingshot	0.016
Fas2	Fasciclin 2	0.016
ed	echinoid	0.016
skpF	CG12227 gene product from transcript CG12227-RA	0.016
sina	seven in absentia	0.016
TfIIA-L	Transcription factor IIA L	0.016
pim	pimples	0.016
CG5869	CG5869 gene product from transcript CG5869-RA	0.016
eff	effete	0.015
Syx1A	Syntaxin 1A	0.015
drk	downstream of receptor kinase	0.015
rev7	CG2948 gene product from transcript CG2948-RA	0.015
CG5568	CG5568 gene product from transcript CG5568-RA	0.015
Bre1	CG10542 gene product from transcript CG10542-RA	0.015
CG1307	CG1307 gene product from transcript CG1307-RB	0.015
Synd	Syndapin	0.015
ntc	nutcracker	0.015
TwdlE	TweedleE	0.015
CSN7	COP9 complex homolog subunit 7	0.015
Uev1A	CG10640 gene product from transcript CG10640-RA	0.015
EndoGI	Endonuclease G inhibitor	0.015
TppII	tripeptidyl-peptidase II	0.015
rap	retina aberrant in pattern	0.015
gukh	GUK-holder	0.015
CG6455	CG6455 gene product from transcript CG6455-RC	0.014
CG14907	CG14907 gene product from transcript CG14907-RB	0.014
CG18292	CG18292 gene product from transcript CG18292-RA	0.014
Wnk	CG7177 gene product from transcript CG7177-RA	0.014
HSPC300	CG30173 gene product from transcript CG30173-RA	0.014
skd	skuld	0.014
skpB	CG8881 gene product from transcript CG8881-RA	0.014	Fly
moi	modigliani	0.014
Crk	CG1587 gene product from transcript CG1587-RC	0.014
CG12424	CG12424 gene product from transcript CG12424-RC	0.014
skap	skpA associated protein	0.014
vri	vrille	0.014
kay	kayak	0.014
vari	varicose	0.014
Treh	Trehalase	0.014
CG2865	CG2865 gene product from transcript CG2865-RA	0.014
CG9304	CG9304 gene product from transcript CG9304-RA	0.014
Su(dx)	Suppressor of deltex	0.014
Gug	Grunge	0.014
MESR4	Misexpression suppressor of ras 4	0.014
Rbf	Retinoblastoma-family protein	0.014
Trc8	CG2304 gene product from transcript CG2304-RB	0.014
h	hairy	0.013
Akt1	CG4006 gene product from transcript CG4006-RA	0.013
fan	farinelli	0.013
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.013
mtTFB2	mitochondrial transcription factor B2	0.013
O-fut1	O-fucosyltransferase 1	0.013
CG13373	CG13373 gene product from transcript CG13373-RB	0.013
sbr	small bristles	0.013
sd	scalloped	0.013
gish	gilgamesh	0.013
exd	extradenticle	0.013
TfIIB	Transcription factor IIB	0.013
CG32556	CG32556 gene product from transcript CG32556-RB	0.013
kis	kismet	0.013
tsh	teashirt	0.013
Pink1	PTEN-induced putative kinase 1	0.013
snf	sans fille	0.013
CSN6	COP9 complex homolog subunit 6	0.013
HLH4C	Helix loop helix protein 4C	0.013
Rpn6	Proteasome p44.5 subunit	0.013
CG5783	CG5783 gene product from transcript CG5783-RA	0.013
CHORD	CG6198 gene product from transcript CG6198-RA	0.013
kermit	CG11546 gene product from transcript CG11546-RB	0.013	Mouse
CG4266	CG4266 gene product from transcript CG4266-RA	0.013
Nlp	Nucleoplasmin	0.013
Ptpmeg	CG1228 gene product from transcript CG1228-RD	0.013
CG9986	CG9986 gene product from transcript CG9986-RA	0.013
CG17385	CG17385 gene product from transcript CG17385-RA	0.013
mtrm	matrimony	0.013
CG7889	CG7889 gene product from transcript CG7889-RA	0.013
CG34159	CG34159 gene product from transcript CG34159-RA	0.013
hep	hemipterous	0.013
mge	maggie	0.013
Ntf-2	Nuclear transport factor-2	0.012
synj	synaptojanin	0.012
GluRIIA	Glutamate receptor IIA	0.012
Stim	Stromal interaction molecule	0.012
CG5857	CG5857 gene product from transcript CG5857-RA	0.012
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.012
CG4050	CG4050 gene product from transcript CG4050-RA	0.012
CG14932	CG14932 gene product from transcript CG14932-RC	0.012
Lis-1	Lissencephaly-1	0.012
CG4286	CG4286 gene product from transcript CG4286-RA	0.012
dally	division abnormally delayed	0.012
Ice	CG7788 gene product from transcript CG7788-RA	0.012
CG17564	CG17564 gene product from transcript CG17564-RB	0.012
CG8979	CG8979 gene product from transcript CG8979-RC	0.012
bs	blistered	0.012
iHog	interference Hedgehog	0.012
CG5515	CG5515 gene product from transcript CG5515-RA	0.012
Lasp	CG3849 gene product from transcript CG3849-RB	0.012
miple	CG1221 gene product from transcript CG1221-RA	0.012
Karybeta3	Karyopherin beta 3	0.012
lcs	la costa	0.011
Ddx1	Dead-box-1	0.011
CG31917	CG31917 gene product from transcript CG31917-RA	0.011
jing	CG9397 gene product from transcript CG9397-RI	0.011
CycA	Cyclin A	0.011
Prosalpha6T	Proteasome alpha6T subunit	0.011
CG4036	CG4036 gene product from transcript CG4036-RC	0.011
CG32236	CG32236 gene product from transcript CG32236-RA	0.011
CG14937	CG14937 gene product from transcript CG14937-RA	0.011
CG13114	CG13114 gene product from transcript CG13114-RB	0.011
lwr	lesswright	0.011
dm	diminutive	0.011
ft	fat	0.011
CG32772	CG32772 gene product from transcript CG32772-RC	0.011
plu	plutonium	0.011
da	daughterless	0.011	Mouse
CG11980	CG11980 gene product from transcript CG11980-RB	0.011
nudC	CG9710 gene product from transcript CG9710-RA	0.011
Psc	Posterior sex combs	0.011
CG14053	CG14053 gene product from transcript CG14053-RA	0.011
Drp1	Dynamin related protein 1	0.011
Sulf1	Sulfated	0.011
CG6845	CG6845 gene product from transcript CG6845-RE	0.011
Sbf	SET domain binding factor	0.011
daw	dawdle	0.011
poe	purity of essence	0.011
aux	auxillin	0.011
Mcm10	Sensitized chromosome inheritance modifier 19	0.011
nej	nejire	0.011
S6k	RPS6-p70-protein kinase	0.011
CG31122	CG31122 gene product from transcript CG31122-RA	0.011
FBX011	FBX011 ortholog	0.011
MrgBP	CG13746 gene product from transcript CG13746-RA	0.011
CG3587	CG3587 gene product from transcript CG3587-RA	0.011
CG15098	CG15098 gene product from transcript CG15098-RA	0.011
glec	gliolectin	0.010
CG14683	CG14683 gene product from transcript CG14683-RA	0.010
CG17086	CG17086 gene product from transcript CG17086-RA	0.010
EndoG	Endonuclease G	0.010
CG3342	CG3342 gene product from transcript CG3342-RA	0.010
spen	split ends	0.010
CG4953	CG4953 gene product from transcript CG4953-RA	0.010
bdg	bedraggled	0.010
Ca-P60A	Calcium ATPase at 60A	0.010
morgue	modifier of rpr and grim, ubiquitously expressed	0.010
CG42674	CG42674 gene product from transcript CG42674-RE	0.010
CG3492	CG3492 gene product from transcript CG3492-RA	0.010
Psf2	CG18013 gene product from transcript CG18013-RA	0.010
Pcaf	CG4107 gene product from transcript CG4107-RA	0.010	Human
CG12112	CG12112 gene product from transcript CG12112-RA	0.010
disp	dispatched	0.010
CG8446	CG8446 gene product from transcript CG8446-RC	0.010
Mmp2	Matrix metalloproteinase 2	0.010
eIF2B-delta	CG10315 gene product from transcript CG10315-RA	0.010
sec6	CG5341 gene product from transcript CG5341-RA	0.010
CG12263	CG12263 gene product from transcript CG12263-RA	0.010
repo	reversed polarity	0.010