IMP: Integrative Multi-species Prediction

Drosophila melanogaster

34 genes annotated in fly

establishment or maintenance of bipolar cell polarity

Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "establishment or maintenance of bipolar cell polarity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "establishment or maintenance of bipolar cell polarity" (in gray)

Name	Description	Probability	Func Analog Organism
crb	crumbs	0.989
l(2)gl	lethal (2) giant larvae	0.986	Mouse
Rac1	CG2248 gene product from transcript CG2248-RA	0.932
Chc	Clathrin heavy chain	0.891
arm	armadillo	0.870
fz	frizzled	0.855
Rab11	Rab-protein 11	0.810
Vang	Van Gogh	0.752	Mouse
Ras85D	Ras oncogene at 85D	0.742
Cdc42	CG12530 gene product from transcript CG12530-RA	0.555	Mouse
Syx7	Syntaxin 7	0.476
spi	spitz	0.469
cpa	capping protein alpha	0.465
Khc	Kinesin heavy chain	0.443
JIL-1	CG6297 gene product from transcript CG6297-RA	0.437
Arp87C	Actin-related protein 87C	0.431
sktl	skittles	0.415
rok	Rho-kinase	0.409
frc	fringe connection	0.390
ds	dachsous	0.371
aPKC	atypical protein kinase C	0.370
dsh	dishevelled	0.359
trc	tricornered	0.349
par-6	CG5884 gene product from transcript CG5884-RA	0.277
ttk	tramtrack	0.270	Fly
ft	fat	0.266
bowl	brother of odd with entrails limited	0.244
Lis-1	Lissencephaly-1	0.240
schlank	CG3576 gene product from transcript CG3576-RB	0.212
dia	diaphanous	0.201
cora	coracle	0.196
Dhc64C	Dynein heavy chain 64C	0.193
yki	yorkie	0.188
Dlic	Dynein light intermediate chain	0.188
trpl	trp-like	0.175
baz	bazooka	0.167
Gug	Grunge	0.167
mys	myospheroid	0.164
trp	transient receptor potential	0.157
nct	nicastrin	0.152
kug	kugelei	0.145
ric8a	CG15797 gene product from transcript CG15797-RA	0.142
Rbsn-5	Rabenosyn-5	0.140
sqh	spaghetti squash	0.139
Vps28	Vacuolar protein sorting 28	0.138
flr	flare	0.137
par-1	CG8201 gene product from transcript CG8201-RA	0.132
raps	rapsynoid	0.129
Rab5	Rab-protein 5	0.124
wdb	widerborst	0.121
Eb1	CG3265 gene product from transcript CG3265-RF	0.119
sec8	CG2095 gene product from transcript CG2095-RA	0.114
Vhl	von Hippel-Lindau	0.110
pnt	pointed	0.100
cpb	capping protein beta	0.100
dgo	diego	0.096
Jra	Jun-related antigen	0.095
cnn	centrosomin	0.091
Moe	Moesin	0.091
Wnt4	Wnt oncogene analog 4	0.089
raw	CG12437 gene product from transcript CG12437-RB	0.088
Sara	Smad anchor for receptor activation	0.087
lkb1	CG9374 gene product from transcript CG9374-RJ	0.084
gammaCop	gamma-coatomer protein	0.083
egl	egalitarian	0.083
Krn	Keren	0.077
pk	prickle	0.077	Mouse
btz	barentsz	0.077
sec6	CG5341 gene product from transcript CG5341-RA	0.074
wg	wingless	0.074
sdt	stardust	0.071
Sgt1	CG9617 gene product from transcript CG9617-RA	0.070
bib	big brain	0.069
vib	vibrator	0.068
sinah	sina homologue	0.067
shg	shotgun	0.067
bsk	basket	0.062
CG31740	CG31740 gene product from transcript CG31740-RA	0.062
CG10103	CG10103 gene product from transcript CG10103-RA	0.061
Crag	Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein	0.061
Syx5	Syntaxin 5	0.060
sds22	CG5851 gene product from transcript CG5851-RA	0.059
msn	misshapen	0.057
D	Dichaete	0.056
Tak1	TGF-beta activated kinase 1	0.055
scb	scab	0.053
Rala	Ras-related protein	0.052	Fly
hpo	hippo	0.052
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.051
CG34449	CG34449 gene product from transcript CG34449-RB	0.051
rib	ribbon	0.051
gho	ghost	0.050
CG32556	CG32556 gene product from transcript CG32556-RB	0.048
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.047
Rab7	Rab-protein 7	0.046
stan	starry night	0.045
Gbeta76C	G protein beta-subunit 76C	0.044
bab2	CG9102 gene product from transcript CG9102-RA	0.044
Arr2	Arrestin 2	0.043
CG3529	CG3529 gene product from transcript CG3529-RB	0.043
Fas2	Fasciclin 2	0.042
ifc	infertile crescent	0.042
CG6954	CG6954 gene product from transcript CG6954-RB	0.042
klar	klarsicht	0.041
beta-Spec	beta Spectrin	0.041
sec23	CG1250 gene product from transcript CG1250-RA	0.041
vimar	visceral mesodermal armadillo-repeats	0.040
Tre1	trapped in endoderm-1	0.039
VhaAC39	Vacuolar H[+]-ATPase C39 subunit	0.038
ara	araucan	0.037
Med	Medea	0.037
sec5	CG8843 gene product from transcript CG8843-RA	0.037
Nrx-IV	Neurexin IV	0.037
Xpd	Xeroderma pigmentosum D	0.036
Brf	CG31256 gene product from transcript CG31256-RA	0.036
Rho1	CG8416 gene product from transcript CG8416-RB	0.036
CG13144	CG13144 gene product from transcript CG13144-RA	0.036
sano	serrano	0.035
Bsg25D	Blastoderm-specific gene 25D	0.035
bcd	bicoid	0.034
chic	chickadee	0.033
lbl	ladybird late	0.033
CG34168	CG34168 gene product from transcript CG34168-RA	0.033
Vsx2	CG33980 gene product from transcript CG33980-RA	0.033
Rh3	Rhodopsin 3	0.033
MYPT-75D	CG6896 gene product from transcript CG6896-RA	0.032
Rh5	Rhodopsin 5	0.031
nmo	nemo	0.030
ovo	CG6824 gene product from transcript CG6824-RE	0.029
G-oalpha47A	G protein oalpha 47A	0.028
fj	four-jointed	0.028
pex13	peroxin 13	0.027
sn	singed	0.027
wb	wing blister	0.026
Ctr1A	Copper transporter 1A	0.026
ninaE	neither inactivation nor afterpotential E	0.026
pUf68	poly U binding factor 68kD	0.026
vps2	CG14542 gene product from transcript CG14542-RA	0.025
tsg	twisted gastrulation	0.025
drm	drumstick	0.025
R	Roughened	0.025
Bap	Beta Adaptin	0.024
Rheb	CG1081 gene product from transcript CG1081-RA	0.024
Hph	HIF prolyl hydroxylase	0.024
bru	brunelleschi	0.024
insc	inscuteable	0.024
SoxN	SoxNeuro	0.023
TSG101	tumor suppressor protein 101	0.023
CG9139	CG9139 gene product from transcript CG9139-RA	0.023
aop	anterior open	0.023
gcl	germ cell-less	0.023
cno	canoe	0.023
CalpB	Calpain-B	0.023
endos	endosulfine	0.023
ssh	slingshot	0.022
stau	staufen	0.022
rux	roughex	0.021
stumps	CG31317 gene product from transcript CG31317-RC	0.021
Syx16	Syntaxin 16	0.021
Mnt	CG13316 gene product from transcript CG13316-RD	0.021
Nipped-A	CG33554 gene product from transcript CG33554-RE	0.021
Sop2	Suppressor of profilin 2	0.021
bip1	CG7574 gene product from transcript CG7574-RA	0.021
opa	odd paired	0.021
dbo	diablo	0.021
G-ialpha65A	G protein alphai subunit 65A	0.020
CG8909	CG8909 gene product from transcript CG8909-RC	0.020
ZnT35C	CG3994 gene product from transcript CG3994-RA	0.020
Spn77Ba	Serpin 77Ba	0.020
SH3PX1	CG6757 gene product from transcript CG6757-RA	0.020
Rop	Ras opposite	0.020
wkd	whacked	0.019
Mmp1	Matrix metalloproteinase 1	0.019
Hr96	Hormone receptor-like in 96	0.019
stck	steamer duck	0.019
Drp1	Dynamin related protein 1	0.019
CHMP2B	Charged multivesicular body protein 2b	0.019
Vps45	Vacuolar protein sorting 45	0.019
CG11138	CG11138 gene product from transcript CG11138-RC	0.019
inaC	inactivation no afterpotential C	0.019
wun2	wunen-2	0.018
CG32647	CG32647 gene product from transcript CG32647-RB	0.018
eIF4E-3	CG8023 gene product from transcript CG8023-RA	0.018
ird1	immune response deficient 1	0.018
SCAR	CG4636 gene product from transcript CG4636-RA	0.018
pex1	peroxin 1	0.018
ea	easter	0.018
Dl	Delta	0.018
alpha-Spec	alpha Spectrin	0.017
CoRest	CG42687 gene product from transcript CG42687-RC	0.017
mei-P26	CG12218 gene product from transcript CG12218-RA	0.017
CG1115	CG1115 gene product from transcript CG1115-RA	0.017
rhea	CG6831 gene product from transcript CG6831-RA	0.017
ens	ensconsin	0.017
eca	eclair	0.017
stl	stall	0.017
CG14712	CG14712 gene product from transcript CG14712-RA	0.017
fry	furry	0.017
tsr	twinstar	0.017
mats	mob as tumor suppressor	0.017
GckIII	Germinal centre kinase III	0.017
Cog7	CG31040 gene product from transcript CG31040-RA	0.016
Apc2	Adenomatous polyposis coli tumor suppressor homolog 2	0.016
Flo-2	flotillin 2	0.016
Cap-G	CG34438 gene product from transcript CG34438-RF	0.016
CG6116	CG6116 gene product from transcript CG6116-RA	0.016
Gbeta13F	G protein beta-subunit 13F	0.016
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.016
Dmn	Dynamitin	0.016
CG8709	CG8709 gene product from transcript CG8709-RK	0.016
cenB1A	centaurin beta 1A	0.016
CG13032	CG13032 gene product from transcript CG13032-RA	0.016
tsh	teashirt	0.016
Rbf	Retinoblastoma-family protein	0.016
l(2)k14710	lethal (2) k14710	0.015
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.015
CG12042	CG12042 gene product from transcript CG12042-RA	0.015
phol	pleiohomeotic like	0.015
kay	kayak	0.015
CG15764	CG15764 gene product from transcript CG15764-RA	0.015
mol	moladietz	0.015
CG6664	CG6664 gene product from transcript CG6664-RC	0.015
vas	vasa	0.015
Osbp	Oxysterol binding protein	0.015
Arf51F	ADP ribosylation factor 51F	0.015
CG13636	CG13636 gene product from transcript CG13636-RB	0.015
l(2)08717	lethal (2) 08717	0.015
CG34400	CG34400 gene product from transcript CG34400-RD	0.015
ci	cubitus interruptus	0.015
Sln	Silnoon	0.015
nudE	CG8104 gene product from transcript CG8104-RB	0.014
CRMP	Collapsin Response Mediator Protein	0.014
kkv	krotzkopf verkehrt	0.014
Rab2	Rab-protein 2	0.014
CG18754	CG18754 gene product from transcript CG18754-RB	0.014
Rh6	Rhodopsin 6	0.014
CG17019	CG17019 gene product from transcript CG17019-RA	0.014
AP-50	CG7057 gene product from transcript CG7057-RB	0.014
CycE	Cyclin E	0.014
ed	echinoid	0.014
rho-5	rhomboid-5	0.014
Arpc3B	CG8936 gene product from transcript CG8936-RA	0.014
Ggamma1	G protein gamma 1	0.014
pll	pelle	0.014
norpA	no receptor potential A	0.014
Ctr1B	Copper transporter 1B	0.014
Cyp18a1	Cytochrome P450-18a1	0.013
arr	arrow	0.013
Snx6	CG8282 gene product from transcript CG8282-RA	0.013
Tm1	Tropomyosin 1	0.013
CG12333	CG12333 gene product from transcript CG12333-RA	0.013
grh	grainy head	0.013
Timp	Tissue inhibitor of metalloproteases	0.013
Mst84Db	Male-specific RNA 84Db	0.013
Usf	CG17592 gene product from transcript CG17592-RB	0.013
byn	brachyenteron	0.013
sgl	sugarless	0.013
CG11876	CG11876 gene product from transcript CG11876-RA	0.013
CG8301	CG8301 gene product from transcript CG8301-RA	0.013
CG6619	CG6619 gene product from transcript CG6619-RA	0.013
CadN	Cadherin-N	0.013
sav	salvador	0.013
Snap24	Synapse protein 24	0.013
CG17265	CG17265 gene product from transcript CG17265-RA	0.013
mop	myopic	0.013
in	inturned	0.013
nod	no distributive disjunction	0.013
lft	lowfat	0.013
asl	asterless	0.013
CTCF	CG8591 gene product from transcript CG8591-RA	0.013
Taspase1	Taspase 1	0.013
fws	four way stop	0.012
Cnx99A	Calnexin 99A	0.012
Nhe2	Na[+]/H[+] hydrogen exchanger 2	0.012
CG14782	CG14782 gene product from transcript CG14782-RA	0.012
ns2	nucleostemin 2	0.012
nrv2	nervana 2	0.012
CG4213	CG4213 gene product from transcript CG4213-RA	0.012
Tektin-A	Tektin A	0.012
Ilk	Integrin linked kinase	0.012	Mouse
CG8329	CG8329 gene product from transcript CG8329-RA	0.012
wts	warts	0.012
Sp1	CG1343 gene product from transcript CG1343-RB	0.012
hkb	huckebein	0.012
Ca-alpha1T	CG15899 gene product from transcript CG15899-RC	0.012
CG12026	CG12026 gene product from transcript CG12026-RB	0.012
N	Notch	0.012
CG4558	CG4558 gene product from transcript CG4558-RA	0.012
mtg	mind the gap	0.012
CG11178	CG11178 gene product from transcript CG11178-RA	0.012
CG4617	CG4617 gene product from transcript CG4617-RA	0.012
l(2)35Bg	lethal (2) 35Bg	0.012
lsn	larsen	0.012
ftz-f1	ftz transcription factor 1	0.012
scat	scattered	0.012
Vha100-1	CG1709 gene product from transcript CG1709-RF	0.012
slou	slouch	0.012
chn	charlatan	0.012
CG18094	CG18094 gene product from transcript CG18094-RA	0.012
Ant2	Adenine nucleotide translocase 2	0.011
ninaC	neither inactivation nor afterpotential C	0.011
CrebA	Cyclic-AMP response element binding protein A	0.011
Rab26	CG34410 gene product from transcript CG34410-RB	0.011
Lip3	CG8823 gene product from transcript CG8823-RA	0.011
otk	off-track	0.011	Mouse
ome	omega	0.011
Cul-5	Cullin-5	0.011
mfrn	mitoferrin	0.011
trpm	CG34123 gene product from transcript CG34123-RG	0.011
l(2)k16918	lethal (2) k16918	0.011
CdGAPr	CG10538 gene product from transcript CG10538-RA	0.011
smg	smaug	0.011
grk	gurken	0.011
rn	rotund	0.011
slbo	slow border cells	0.011
mid	midline	0.011
ImpE1	Ecdysone-inducible gene E1	0.011
CycY	Cyclin Y	0.011
eya	eyes absent	0.011	Mouse
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.011
bam	bag of marbles	0.011
srw	shrew	0.011
CG32528	CG32528 gene product from transcript CG32528-RA	0.011
CG14868	CG14868 gene product from transcript CG14868-RA	0.011
Exn	Ephexin	0.010
Vps25	Vacuolar protein sorting 25	0.010
endoB	endophilin B	0.010
CG3125	CG3125 gene product from transcript CG3125-RA	0.010
sno	strawberry notch	0.010
Shc	SHC-adaptor protein	0.010
Rbp9	RNA-binding protein 9	0.010
nullo	CG14426 gene product from transcript CG14426-RB	0.010
alpha-Man-IIb	CG4606 gene product from transcript CG4606-RA	0.010
ru	roughoid	0.010
Blimp-1	CG5249 gene product from transcript CG5249-RA	0.010
Vrp1	Verprolin 1	0.010
fng	fringe	0.010
santa-maria	scavenger receptor acting in neural tissue and majority of rhodopsin is absent	0.010
ATbp	(A+T)-stretch binding protein	0.010
sha	shavenoid	0.010
Su(Tpl)	CG32217 gene product from transcript CG32217-RB	0.010
sfl	sulfateless	0.010