IMP: Integrative Multi-species Prediction

Drosophila melanogaster

43 genes annotated in fly

regulation of tube size open tracheal system

Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of tube size open tracheal system"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of tube size open tracheal system" (in gray)

Name	Description	Probability	Func Analog Organism
sinu	sinuous	1.000
Tsf2	Transferrin 2	1.000
CG2813	CG2813 gene product from transcript CG2813-RA	0.999
vari	varicose	0.997
pck	pickel	0.996
gho	ghost	0.993
Nrx-IV	Neurexin IV	0.992
Rho1	CG8416 gene product from transcript CG8416-RB	0.980
CG17218	CG17218 gene product from transcript CG17218-RA	0.967
knk	knickkopf	0.961
Mcr	Macroglobulin complement-related	0.937
kug	kugelei	0.934
conv	convoluted	0.922
ds	dachsous	0.922
grh	grainy head	0.918
mmy	mummy	0.894
cora	coracle	0.843
Egfr	Epidermal growth factor receptor	0.830
crb	crumbs	0.825
wun	wunen	0.823
wg	wingless	0.809
Atpalpha	Na pump alpha subunit	0.760
Cont	Contactin	0.757
uif	uninflatable	0.729
Vang	Van Gogh	0.715
Moe	Moesin	0.679
kkv	krotzkopf verkehrt	0.673
sec23	CG1250 gene product from transcript CG1250-RA	0.654
CG8121	CG8121 gene product from transcript CG8121-RA	0.648
ft	fat	0.638
fz	frizzled	0.620
Rac1	CG2248 gene product from transcript CG2248-RA	0.614
fng	fringe	0.572
form3	formin 3	0.568
rtv	retroactive	0.564
CG1298	CG1298 gene product from transcript CG1298-RA	0.539
verm	vermiform	0.533
bou	boudin	0.513
Timp	Tissue inhibitor of metalloproteases	0.484
Vhl	von Hippel-Lindau	0.446
nrv2	nervana 2	0.431
mew	multiple edematous wings	0.408
sano	serrano	0.387
fj	four-jointed	0.383
ttk	tramtrack	0.381
obst-A	obstructor-A	0.360
shg	shotgun	0.351
nej	nejire	0.333
CG1927	CG1927 gene product from transcript CG1927-RA	0.323
Fas2	Fasciclin 2	0.322
CG10217	CG10217 gene product from transcript CG10217-RB	0.265
Cht2	Chitinase 2	0.211
btl	breathless	0.208
Cdc42	CG12530 gene product from transcript CG12530-RA	0.204
kni	knirps	0.187
serp	serpentine	0.175
vvl	ventral veins lacking	0.172
gammaCop	gamma-coatomer protein	0.164
Cad99C	CG31009 gene product from transcript CG31009-RB	0.159
east	enhanced adult sensory threshold	0.157
bnl	branchless	0.146
pk	prickle	0.134
ci	cubitus interruptus	0.134
scb	scab	0.129
tkv	thickveins	0.129
rok	Rho-kinase	0.121
Catsup	Catecholamines up	0.118
Gyc76C	Guanylyl cyclase at 76C	0.116
pnt	pointed	0.101
Btk29A	Btk family kinase at 29A	0.100
rib	ribbon	0.099	Fly
sfl	sulfateless	0.097
jing	CG9397 gene product from transcript CG9397-RI	0.097
rin	rasputin	0.091
mys	myospheroid	0.090
Peb	Protein ejaculatory bulb	0.088
eya	eyes absent	0.086
hth	homothorax	0.085
CG6583	CG6583 gene product from transcript CG6583-RA	0.080
CG32556	CG32556 gene product from transcript CG32556-RB	0.079
Gpdh	Glycerol 3 phosphate dehydrogenase	0.075
pyd	polychaetoid	0.072
pio	piopio	0.070
Mmp1	Matrix metalloproteinase 1	0.069
CG3624	CG3624 gene product from transcript CG3624-RA	0.068
Mrtf	Myocardin-related transcription factor	0.065
Blimp-1	CG5249 gene product from transcript CG5249-RA	0.064
CG15861	CG15861 gene product from transcript CG15861-RA	0.063
sima	similar	0.059
mtg	mind the gap	0.057
arm	armadillo	0.057
wb	wing blister	0.056
Src42A	Src oncogene at 42A	0.054
bsk	basket	0.052
Cyp6a23	CG10242 gene product from transcript CG10242-RA	0.050
CG13921	CG13921 gene product from transcript CG13921-RB	0.050
Jhe	Juvenile hormone esterase	0.049
Gp93	Glycoprotein 93	0.049
Bsg25D	Blastoderm-specific gene 25D	0.049
vkg	viking	0.048
CG3305	CG3305 gene product from transcript CG3305-RA	0.048
trc	tricornered	0.048
lft	lowfat	0.046
Est-6	Esterase 6	0.044
Ptpmeg	CG1228 gene product from transcript CG1228-RD	0.043
Psc	Posterior sex combs	0.043
cher	cheerio	0.042
salm	spalt major	0.041
in	inturned	0.041
CG5346	CG5346 gene product from transcript CG5346-RA	0.040
Chc	Clathrin heavy chain	0.040
CG18745	CG18745 gene product from transcript CG18745-RA	0.039
Hs6st	Heparan sulfate 6-O-sulfotransferase	0.038
Tollo	CG6890 gene product from transcript CG6890-RA	0.038
scrib	scribbled	0.038
CG31743	CG31743 gene product from transcript CG31743-RA	0.037
Trh	Tryptophan hydroxylase	0.037
baz	bazooka	0.036
dome	domeless	0.036
CG9867	CG9867 gene product from transcript CG9867-RA	0.035
dnd	dead end	0.035
p115	CG1422 gene product from transcript CG1422-RA	0.034
CG31740	CG31740 gene product from transcript CG31740-RA	0.034
LanB2	Laminin B2	0.034
alpha-Est8	alpha-Esterase-8	0.034	Fly
Akap200	A kinase anchor protein 200	0.033
CG5397	CG5397 gene product from transcript CG5397-RA	0.033
inx3	innexin 3	0.033
Wnt4	Wnt oncogene analog 4	0.032
esg	escargot	0.032
Tsp42Ee	Tetraspanin 42Ee	0.031
CG10188	CG10188 gene product from transcript CG10188-RB	0.031
Hmgcr	HMG Coenzyme A reductase	0.031
Jra	Jun-related antigen	0.030
Tom	Twin of m4	0.030
CG5726	CG5726 gene product from transcript CG5726-RA	0.029
hep	hemipterous	0.029
Sytalpha	Synaptotagmin alpha	0.029
ko	knockout	0.028
dpr3	CG33516 gene product from transcript CG33516-RB	0.028
Cyp12c1	CG4120 gene product from transcript CG4120-RA	0.028
wgn	wengen	0.028
ogre	optic ganglion reduced	0.028
dpr2	CG33507 gene product from transcript CG33507-RB	0.027
CG14741	CG14741 gene product from transcript CG14741-RB	0.027
sgl	sugarless	0.027
CG8600	CG8600 gene product from transcript CG8600-RB	0.027
Fhos	CG42610 gene product from transcript CG42610-RC	0.026
Cyp4d8	Cytochrome P450-4d8	0.026
CG3246	CG3246 gene product from transcript CG3246-RA	0.026
fd59A	forkhead domain 59A	0.026
stl	stall	0.026
Dp1	Dodeca-satellite-binding protein 1	0.025
slbo	slow border cells	0.025
Syx16	Syntaxin 16	0.025
Nrg	Neuroglian	0.024
hh	hedgehog	0.024
CrebA	Cyclic-AMP response element binding protein A	0.024
Lsp1beta	Larval serum protein 1 beta	0.023
jar	jaguar	0.023
stan	starry night	0.022
CG7607	CG7607 gene product from transcript CG7607-RA	0.022
par-1	CG8201 gene product from transcript CG8201-RA	0.022
CG10413	CG10413 gene product from transcript CG10413-RA	0.021
kel	kelch	0.021
CHKov1	CG10618 gene product from transcript CG10618-RB	0.020
Pvf1	PDGF- and VEGF-related factor 1	0.020
LRP1	LDL receptor protein 1	0.020
CG15658	CG15658 gene product from transcript CG15658-RA	0.020
Ten-m	Tenascin major	0.020
CG4328	CG4328 gene product from transcript CG4328-RB	0.020
Trp1	Translocation protein 1	0.019
CG9780	CG9780 gene product from transcript CG9780-RA	0.019
Cyp4ac1	CG14032 gene product from transcript CG14032-RA	0.019
CG10420	CG10420 gene product from transcript CG10420-RA	0.019
CG33307	CG33307 gene product from transcript CG33307-RA	0.019
CG31869	CG31869 gene product from transcript CG31869-RA	0.019
CG6038	CG6038 gene product from transcript CG6038-RA	0.019
shot	short stop	0.019
CalpB	Calpain-B	0.018
klu	klumpfuss	0.018
su(f)	suppressor of forked	0.018
Myo10A	unconventional myosin class XV	0.017
bowl	brother of odd with entrails limited	0.017
dgo	diego	0.017
CG10425	CG10425 gene product from transcript CG10425-RA	0.017
CG17928	CG17928 gene product from transcript CG17928-RA	0.017
alpha-Est5	alpha-Esterase-5	0.017
Cul-5	Cullin-5	0.017
deltaCOP	delta-coatomer protein	0.017
CG34449	CG34449 gene product from transcript CG34449-RB	0.017
Spn5	Serine protease inhibitor 5	0.017
CG4335	CG4335 gene product from transcript CG4335-RA	0.017
N	Notch	0.016
Tango13	Transport and Golgi organization 13	0.016
GalNAc-T1	CG8182 gene product from transcript CG8182-RA	0.016
CG12594	CG12594 gene product from transcript CG12594-RA	0.016
l(2)05510	lethal (2) 05510	0.016
CG8034	CG8034 gene product from transcript CG8034-RA	0.016
Ugt86Dd	CG6633 gene product from transcript CG6633-RB	0.016
wus	wurst	0.016
Cyp12d1-p	CG30489 gene product from transcript CG30489-RA	0.015
mirr	mirror	0.015
CG6959	CG6959 gene product from transcript CG6959-RA	0.015
CG7990	CG7990 gene product from transcript CG7990-RA	0.015
CG14442	CG14442 gene product from transcript CG14442-RB	0.015
Pgant35A	Polypeptide N-acetylgalactosaminyltransferase 35A	0.015
Upf2	CG2253 gene product from transcript CG2253-RA	0.015
rev7	CG2948 gene product from transcript CG2948-RA	0.015
Rab11	Rab-protein 11	0.015
CG13636	CG13636 gene product from transcript CG13636-RB	0.015
CG10512	CG10512 gene product from transcript CG10512-RA	0.015
Cctgamma	CG8977 gene product from transcript CG8977-RC	0.015
Oli	Olig family	0.015
PHDP	Putative homeodomain protein	0.015
CG12424	CG12424 gene product from transcript CG12424-RC	0.014
zip	zipper	0.014
CG1402	CG1402 gene product from transcript CG1402-RB	0.014
lute	CG5319 gene product from transcript CG5319-RA	0.014
CG10147	CG10147 gene product from transcript CG10147-RA	0.014
AR-2	Allatostatin Receptor 2	0.014
odd	odd skipped	0.014
CG3777	CG3777 gene product from transcript CG3777-RB	0.014
dbo	diablo	0.014
ck	crinkled	0.014
vig	vasa intronic gene	0.014
CG8216	CG8216 gene product from transcript CG8216-RA	0.014
frtz	fritz	0.014
CG9396	CG9396 gene product from transcript CG9396-RA	0.014
Oatp33Ea	Organic anion transporting polypeptide 33Ea	0.014
Rab23	CG2108 gene product from transcript CG2108-RA	0.014
CG17191	CG17191 gene product from transcript CG17191-RA	0.014
l(3)04053	lethal (3) 04053	0.014
CG6361	CG6361 gene product from transcript CG6361-RA	0.013
CG5966	CG5966 gene product from transcript CG5966-RA	0.013
CG13721	CG13721 gene product from transcript CG13721-RA	0.013
drl	derailed	0.013
CG32544	CG32544 gene product from transcript CG32544-RA	0.013
SP1029	CG11956 gene product from transcript CG11956-RB	0.013
CG7713	CG7713 gene product from transcript CG7713-RA	0.013
CG3726	CG3726 gene product from transcript CG3726-RA	0.013
CG11852	CG11852 gene product from transcript CG11852-RA	0.013
alpha-Est1	alpha-Esterase-1	0.013	Fly
CG12991	CG12991 gene product from transcript CG12991-RA	0.013
Spn42Dc	Serpin 42Dc	0.013
svp	seven up	0.013
nullo	CG14426 gene product from transcript CG14426-RB	0.013
mwh	multiple wing hairs	0.013
Sap-r	Saposin-related	0.012
drm	drumstick	0.012
Ino80	CG31212 gene product from transcript CG31212-RA	0.012
bip1	CG7574 gene product from transcript CG7574-RA	0.012
gbb	glass bottom boat	0.012
Cyp6w1	CG8345 gene product from transcript CG8345-RA	0.012
l(2)dtl	lethal-(2)-denticleless	0.012
osm-1	CG13809 gene product from transcript CG13809-RA	0.012
CG42666	CG42666 gene product from transcript CG42666-RE	0.012
Clic	Chloride intracellular channel	0.012
CG14445	CG14445 gene product from transcript CG14445-RA	0.012
su(r)	suppressor of rudimentary	0.012
yellow-g2	CG13804 gene product from transcript CG13804-RA	0.012
Duox	Dual oxidase	0.012
CG13830	CG13830 gene product from transcript CG13830-RD	0.012
CG12496	CG12496 gene product from transcript CG12496-RA	0.012
CG11069	CG11069 gene product from transcript CG11069-RA	0.012
CG10126	CG10126 gene product from transcript CG10126-RB	0.012
DnaJ-1	DnaJ-like-1	0.012
CDase	Ceramidase	0.012
Mip	Myoinhibiting peptide precursor	0.012
Gasp	CG10287 gene product from transcript CG10287-RB	0.012
GalNAc-T2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2	0.012
dys	dysfusion	0.012
CG8944	CG8944 gene product from transcript CG8944-RB	0.012
sktl	skittles	0.012
CG7997	CG7997 gene product from transcript CG7997-RB	0.012
CG4699	CG4699 gene product from transcript CG4699-RJ	0.012
dally	division abnormally delayed	0.012
P58IPK	CG8286 gene product from transcript CG8286-RA	0.012
CG4496	CG4496 gene product from transcript CG4496-RA	0.012
Cyp28a5	CG8864 gene product from transcript CG8864-RA	0.012
CG33110	CG33110 gene product from transcript CG33110-RA	0.012
inx2	innexin 2	0.012
CG16723	CG16723 gene product from transcript CG16723-RA	0.012
CG11149	CG11149 gene product from transcript CG11149-RD	0.012
CG11842	CG11842 gene product from transcript CG11842-RA	0.012
CG11694	CG11694 gene product from transcript CG11694-RA	0.012
CG15365	CG15365 gene product from transcript CG15365-RA	0.012
otk	off-track	0.012
CG16898	CG16898 gene product from transcript CG16898-RA	0.011
CG6619	CG6619 gene product from transcript CG6619-RA	0.011
CG16771	CG16771 gene product from transcript CG16771-RC	0.011
GluRIIA	Glutamate receptor IIA	0.011
Sas	Sialic acid phosphate synthase	0.011
Ets21C	Ets at 21C	0.011
Lip3	CG8823 gene product from transcript CG8823-RA	0.011
dpr	defective proboscis extension response	0.011
CG8316	CG8316 gene product from transcript CG8316-RA	0.011
CG9917	CG9917 gene product from transcript CG9917-RA	0.011
Ance-4	CG8196 gene product from transcript CG8196-RA	0.011
CG5758	CG5758 gene product from transcript CG5758-RC	0.011
CG14528	CG14528 gene product from transcript CG14528-RA	0.011
Jupiter	CG31363 gene product from transcript CG31363-RD	0.011
CG9335	CG9335 gene product from transcript CG9335-RA	0.011
dpr7	CG33481 gene product from transcript CG33481-RC	0.011
fat-spondin	CG6953 gene product from transcript CG6953-RB	0.011
Ero1L	Endoplasmic reticulum oxidoreductin-1-like	0.011
ATbp	(A+T)-stretch binding protein	0.011
pan	pangolin	0.011
sog	short gastrulation	0.011
CG3548	CG3548 gene product from transcript CG3548-RA	0.011
if	inflated	0.011
CG6425	CG6425 gene product from transcript CG6425-RA	0.011
katanin-60	katanin 60	0.011
Cpr92F	Cuticular protein 92F	0.011
CG14010	CG14010 gene product from transcript CG14010-RC	0.011	Fly
amd	alpha methyl dopa-resistant	0.011
pot	papillote	0.011
Rbp9	RNA-binding protein 9	0.011
mol	moladietz	0.011
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.011
aPKC	atypical protein kinase C	0.011
CG15643	CG15643 gene product from transcript CG15643-RA	0.011
CG32447	CG32447 gene product from transcript CG32447-RB	0.011
Faa	Fumarylacetoacetase	0.010
ETH	Ecdysis triggering hormone	0.010
CG18437	CG18437 gene product from transcript CG18437-RB	0.010
Nrk	Neurospecific receptor kinase	0.010
TwdlN	TweedleN	0.010
Pu	Punch	0.010
Sema-1b	CG6446 gene product from transcript CG6446-RA	0.010
Fmrf	FMRFamide-related	0.010
Rab9	CG9994 gene product from transcript CG9994-RA	0.010
TpnC41C	Troponin C at 41C	0.010
CG3091	CG3091 gene product from transcript CG3091-RA	0.010
Dot	Dorothy	0.010
NUCB1	CG32190 gene product from transcript CG32190-RA	0.010
HP5	Heterochromatin protein 5	0.010
CG11453	CG11453 gene product from transcript CG11453-RA	0.010
alpha-Man-IIb	CG4606 gene product from transcript CG4606-RA	0.010
ry	rosy	0.010
Dpt	Diptericin	0.010
CG9376	CG9376 gene product from transcript CG9376-RA	0.010
Npc2f	Niemann-Pick type C-2f	0.010
Sin1	SAPK-interacting protein 1	0.010