IMP: Integrative Multi-species Prediction

Drosophila melanogaster

28 genes annotated in fly

cellular response to oxidative stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to oxidative stress"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cellular response to oxidative stress" (in gray)

Name	Description	Probability	Func Analog Organism
Sod	Superoxide dismutase	0.997
Cat	Catalase	0.923	Yeast Mouse
p38b	CG7393 gene product from transcript CG7393-RA	0.914
dj-1beta	CG1349 gene product from transcript CG1349-RA	0.875
Trx-2	thioredoxin-2	0.833
CG6783	CG6783 gene product from transcript CG6783-RC	0.780
Jafrac1	thioredoxin peroxidase 1	0.769
Sod2	Superoxide dismutase 2 (Mn)	0.766	Mouse Worm
p53	CG33336 gene product from transcript CG33336-RB	0.766	Human
NLaz	Neural Lazarillo	0.726	Fly
Atg2	Autophagy-specific gene 2	0.570
p120ctn	Adherens junction protein p120	0.477
stai	stathmin	0.476
PHGPx	CG12013 gene product from transcript CG12013-RC	0.413
Thor	CG8846 gene product from transcript CG8846-RA	0.384
Pink1	PTEN-induced putative kinase 1	0.345	Human Mouse Worm
Aldh	Aldehyde dehydrogenase	0.344
Tsp42Ef	Tetraspanin 42Ef	0.326
mth	methuselah	0.287
awd	abnormal wing discs	0.285
LamC	Lamin C	0.262
Ric	Ras which interacts with Calmodulin	0.235
kibra	kibra ortholog	0.183
Mer	Merlin	0.175
CG30410	CG30410 gene product from transcript CG30410-RB	0.155
apt	apontic	0.151
CG6429	CG6429 gene product from transcript CG6429-RA	0.138
Hsp27	Heat shock protein 27	0.135
CG1707	CG1707 gene product from transcript CG1707-RA	0.132
CG13890	CG13890 gene product from transcript CG13890-RA	0.131
CG6543	CG6543 gene product from transcript CG6543-RA	0.128
crm	cramped	0.115
chico	CG5686 gene product from transcript CG5686-RB	0.109
Hsp22	Heat shock protein 22	0.107
Mef2	Myocyte enhancer factor 2	0.105
l(3)82Fd	CG32464 gene product from transcript CG32464-RR	0.101	Mouse
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.101	Rat
Pgam5	Phosphoglycerate mutase 5	0.096
Hsp26	Heat shock protein 26	0.094	Mouse
GLaz	Glial Lazarillo	0.093
dco	discs overgrown	0.087
EcR	Ecdysone receptor	0.084
kay	kayak	0.081	Human
hep	hemipterous	0.078
TwdlL	TweedleL	0.076
tefu	telomere fusion	0.072
spi	spitz	0.072
Zyx102EF	CG32018 gene product from transcript CG32018-RA	0.070
pr-set7	CG3307 gene product from transcript CG3307-RC	0.068
shi	shibire	0.066
Lectin-galC1	Galactose-specific C-type lectin	0.065
Clk	Clock	0.063
ref(2)P	refractory to sigma P	0.063
Ubqn	Ubiquilin	0.063	Human
Src42A	Src oncogene at 42A	0.062
MTF-1	Metal response element-binding Transcription Factor-1	0.062
Tpi	Triose phosphate isomerase	0.062
Hsp68	Heat shock protein 68	0.062
Atg7	Autophagy-specific gene 7	0.061
stmA	stambha A	0.059
fh	frataxin homolog	0.057
CG11151	CG11151 gene product from transcript CG11151-RA	0.057
CG14815	CG14815 gene product from transcript CG14815-RA	0.057
SdhB	Succinate dehydrogenase B	0.056
Pepck	Phosphoenolpyruvate carboxykinase	0.056
sli	slit	0.052
cert	ceramide transfer protein	0.051
CG8155	CG8155 gene product from transcript CG8155-RA	0.051
foxo	forkhead box, sub-group O	0.048
CG42630	CG42630 gene product from transcript CG42630-RA	0.047
CG11877	CG11877 gene product from transcript CG11877-RA	0.046
CG9801	CG9801 gene product from transcript CG9801-RC	0.045
Mekk1	CG7717 gene product from transcript CG7717-RB	0.045
Pten	CG5671 gene product from transcript CG5671-RB	0.045
Atg4	Autophagy-specific gene 4	0.045
abs	abstrakt	0.044
Atf-2	Activating transcription factor-2	0.044
GstE6	Glutathione S transferase E6	0.041
Trap1	CG3152 gene product from transcript CG3152-RA	0.040	Rat
CG6664	CG6664 gene product from transcript CG6664-RC	0.040
fzy	fizzy	0.040
CG1458	CG1458 gene product from transcript CG1458-RA	0.040
CadN	Cadherin-N	0.040
CG11858	CG11858 gene product from transcript CG11858-RA	0.039
regucalcin	CG1803 gene product from transcript CG1803-RA	0.038
Prx5	Peroxiredoxin 5	0.038	Human
Ulp1	CG12359 gene product from transcript CG12359-RA	0.037
DJ-1alpha	CG6646 gene product from transcript CG6646-RA	0.037
ATP7	CG1886 gene product from transcript CG1886-RB	0.036	Mouse
dys	dysfusion	0.036
Cka	Connector of kinase to AP-1	0.036
CG3011	CG3011 gene product from transcript CG3011-RA	0.036
alpha-Est7	alpha-Esterase-7	0.035
Slip1	CG1783 gene product from transcript CG1783-RA	0.035
rpr	reaper	0.035
Rya-r44F	Ryanodine receptor 44F	0.034	Zebrafish
PGRP-SC2	CG14745 gene product from transcript CG14745-RA	0.034
cl	clot	0.033
CG8036	CG8036 gene product from transcript CG8036-RB	0.033
CG9510	CG9510 gene product from transcript CG9510-RC	0.033
CG4858	CG4858 gene product from transcript CG4858-RA	0.032
CG6180	CG6180 gene product from transcript CG6180-RA	0.032
Trxr-1	Thioredoxin reductase-1	0.032
stumps	CG31317 gene product from transcript CG31317-RC	0.031
Khc-73	Kinesin-73	0.031
SpdS	Spermidine Synthase	0.031
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.031
RanBPM	Ran-binding protein M	0.030
cindr	CIN85 and CD2AP orthologue	0.030
fs(2)ltoPP43	female sterile (2) ltoPP43	0.030
cln3	CG5582 gene product from transcript CG5582-RA	0.030
RagA	CG11968 gene product from transcript CG11968-RA	0.030
ey	eyeless	0.030
bsk	basket	0.030
Fatp	Fatty acid (long chain) transport protein	0.030
SNF1A	SNF1A/AMP-activated protein kinase	0.029	Rat
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.029
Eip71CD	Ecdysone-induced protein 28/29kD	0.029
Lnk	CG17367 gene product from transcript CG17367-RC	0.028
CG13319	CG13319 gene product from transcript CG13319-RA	0.028
unc-13	CG2999 gene product from transcript CG2999-RA	0.028
sim	single-minded	0.028
IP3K2	Inositol 1,4,5-triphosphate kinase 2	0.027
C3G	CG42328 gene product from transcript CG42328-RC	0.027
trpml	transient receptor potential mucolipin	0.027
ninaA	neither inactivation nor afterpotential A	0.027
alph	alphabet	0.027
CG14715	CG14715 gene product from transcript CG14715-RA	0.027
Plc21C	Phospholipase C at 21C	0.027
clt	cricklet	0.026
CG4673	CG4673 gene product from transcript CG4673-RB	0.026
sni	sniffer	0.026
CG11093	CG11093 gene product from transcript CG11093-RB	0.026
NtR	CG6698 gene product from transcript CG6698-RA	0.025
sun	stunted	0.025
CG8891	CG8891 gene product from transcript CG8891-RA	0.025
S6k	RPS6-p70-protein kinase	0.025
Mt2	Methyltransferase 2	0.025
Atg9	Autophagy-specific gene 9	0.024
CG2604	CG2604 gene product from transcript CG2604-RA	0.024
CG10103	CG10103 gene product from transcript CG10103-RA	0.024
IP3K1	Inositol 1,4,5-triphosphate kinase 1	0.024
CG6576	CG6576 gene product from transcript CG6576-RA	0.023
W	Wrinkled	0.023
Su(var)3-7	Suppressor of variegation 3-7	0.023
Rfabg	Retinoid- and fatty acid-binding glycoprotein	0.023
CG7054	CG7054 gene product from transcript CG7054-RA	0.023
ia2	CG31795 gene product from transcript CG31795-RD	0.023
mRpL2	mitochondrial ribosomal protein L2	0.023
CG31548	CG31548 gene product from transcript CG31548-RA	0.023
nej	nejire	0.023
CG1140	CG1140 gene product from transcript CG1140-RB	0.022
Inos	CG11143 gene product from transcript CG11143-RA	0.022
Jafrac2	thioredoxin peroxidase 2	0.022
Cyp6g1	CG8453 gene product from transcript CG8453-RA	0.022
CG10638	CG10638 gene product from transcript CG10638-RA	0.021	Human
inaE	inactivation no afterpotential E	0.021
CG6028	CG6028 gene product from transcript CG6028-RA	0.021
pan	pangolin	0.021
Atg8a	Autophagy-specific gene 8a	0.021
mub	mushroom-body expressed	0.021
rno	rhinoceros	0.021
gwl	greatwall	0.021
wit	wishful thinking	0.020
Mlp84B	Muscle LIM protein at 84B	0.020
CG16892	CG16892 gene product from transcript CG16892-RA	0.020
VGlut	Vesicular glutamate transporter	0.020
CG9572	CG9572 gene product from transcript CG9572-RA	0.020
CG30427	CG30427 gene product from transcript CG30427-RC	0.020
e(y)3	enhancer of yellow 3	0.020
Hsp23	Heat shock protein 23	0.020	Mouse
shg	shotgun	0.019
lkb1	CG9374 gene product from transcript CG9374-RJ	0.019
Sir2	CG5216 gene product from transcript CG5216-RA	0.019	Human
metl	methyltransferase-like	0.019
CalpA	Calpain-A	0.019
TBPH	CG10327 gene product from transcript CG10327-RC	0.019
Atpalpha	Na pump alpha subunit	0.019
CG9883	CG9883 gene product from transcript CG9883-RA	0.018
PGRP-LE	Peptidoglycan recognition protein LE	0.018
Arc-p20	CG5972 gene product from transcript CG5972-RA	0.018
CG31937	CG31937 gene product from transcript CG31937-RA	0.018
Dcr-2	Dicer-2	0.018
puc	puckered	0.018
Rheb	CG1081 gene product from transcript CG1081-RA	0.018
CG9027	CG9027 gene product from transcript CG9027-RD	0.018
Zw	Zwischenferment	0.017
CG9471	CG9471 gene product from transcript CG9471-RB	0.017
CG7998	CG7998 gene product from transcript CG7998-RA	0.017
Pi3K59F	Phosphotidylinositol 3 kinase 59F	0.017
mbf1	multiprotein bridging factor 1	0.017
Sos	Son of sevenless	0.017
slpr	slipper	0.017
Adk2	Adenylate kinase-2	0.017
yip2	yippee interacting protein 2	0.017
CG12753	CG12753 gene product from transcript CG12753-RB	0.017
Chd1	Chromodomain-helicase-DNA-binding protein 1	0.017
Jra	Jun-related antigen	0.017
CG11267	CG11267 gene product from transcript CG11267-RA	0.017
dm	diminutive	0.017
drd	drop dead	0.017
lid	little imaginal discs	0.017
CG5139	CG5139 gene product from transcript CG5139-RA	0.017
sea	scheggia	0.016
TotC	Turandot C	0.016	Fly
CG2862	CG2862 gene product from transcript CG2862-RA	0.016
InR	Insulin-like receptor	0.016
Usp7	ubiquitin-specific protease 7	0.016
wnd	wallenda	0.016
Mpk2	CG5475 gene product from transcript CG5475-RB	0.016
S6kII	RPS6-protein kinase-II	0.016
Cpn	Calphotin	0.016
CG16721	CG16721 gene product from transcript CG16721-RA	0.016
CG6673	CG6673 gene product from transcript CG6673-RA	0.016
CG8993	CG8993 gene product from transcript CG8993-RA	0.016
rdgB	retinal degeneration B	0.016
Gr39a	Gustatory receptor 39a	0.016
pim	pimples	0.016
sqz	squeeze	0.016
nudE	CG8104 gene product from transcript CG8104-RB	0.016
Hnf4	Hepatocyte nuclear factor 4	0.015
AnnX	Annexin X	0.015
kkv	krotzkopf verkehrt	0.015
CG15309	CG15309 gene product from transcript CG15309-RA	0.015
Taf2	TBP-associated factor 2	0.015
mav	maverick	0.015
CG9232	CG9232 gene product from transcript CG9232-RA	0.015
Rab10	Rab-protein 10	0.015
CG5830	CG5830 gene product from transcript CG5830-RA	0.015
CanA-14F	Calcineurin A at 14F	0.015
RpS3	Ribosomal protein S3	0.015
PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	0.015
Akap200	A kinase anchor protein 200	0.015
form3	formin 3	0.015
mRpL51	mitochondrial ribosomal protein L51	0.014
RpS4	Ribosomal protein S4	0.014
CG31958	CG31958 gene product from transcript CG31958-RA	0.014
Grip75	CG6176 gene product from transcript CG6176-RA	0.014
CG9914	CG9914 gene product from transcript CG9914-RA	0.014
cbs	centrosomin's beautiful sister	0.014
lz	lozenge	0.014
CG9391	CG9391 gene product from transcript CG9391-RA	0.014
slim	scruin like at the midline	0.014
CG2811	CG2811 gene product from transcript CG2811-RA	0.014
Fkbp13	CG9847 gene product from transcript CG9847-RC	0.014
mus209	mutagen-sensitive 209	0.014
argos	CG4531 gene product from transcript CG4531-RA	0.014
dimm	dimmed	0.014
mus201	mutagen-sensitive 201	0.014
CG3759	CG3759 gene product from transcript CG3759-RB	0.014
HtrA2	CG8464 gene product from transcript CG8464-RA	0.013
Met	Methoprene-tolerant	0.013
CG14614	CG14614 gene product from transcript CG14614-RA	0.013
Crc	Calreticulin	0.013
Snoo	Sno oncogene	0.013
Gip	GIP-like	0.013
A2bp1	Ataxin-2 binding protein 1	0.013
CG7224	CG7224 gene product from transcript CG7224-RB	0.013
gcl	germ cell-less	0.013
Atf6	CG3136 gene product from transcript CG3136-RA	0.013
rl	rolled	0.013
CG33138	CG33138 gene product from transcript CG33138-RA	0.013
CG7970	CG7970 gene product from transcript CG7970-RA	0.013
jigr1	jing interacting gene regulatory 1	0.013
Tctp	Translationally controlled tumor protein	0.013
Gadd45	CG11086 gene product from transcript CG11086-RA	0.013
REG	CG1591 gene product from transcript CG1591-RA	0.013
nudC	CG9710 gene product from transcript CG9710-RA	0.013
TotA	Turandot A	0.013
wts	warts	0.013
CYLD	cylindromatosis	0.013
asf1	anti-silencing factor 1	0.013
CG8677	CG8677 gene product from transcript CG8677-RA	0.013
sls	sallimus	0.012
CG1319	CG1319 gene product from transcript CG1319-RB	0.012
Dredd	Death related ced-3/Nedd2-like protein	0.012
mof	males absent on the first	0.012
Ser	Serrate	0.012
kl-5	male fertility factor kl5	0.012
CG3149	CG3149 gene product from transcript CG3149-RA	0.012
RpS24	Ribosomal protein S24	0.012
MED26	Mediator complex subunit 26	0.012
Atg1	Autophagy-specific gene 1	0.012
CG10880	CG10880 gene product from transcript CG10880-RA	0.012
aop	anterior open	0.012
Krn	Keren	0.012
Traf4	TNF-receptor-associated factor 4	0.012
CG17734	CG17734 gene product from transcript CG17734-RA	0.012
Rac1	CG2248 gene product from transcript CG2248-RA	0.012
Pde8	Phosphodiesterase 8	0.012
Hcf	Host cell factor	0.012
APP-BP1	beta-Amyloid precursor protein binding protein 1	0.012
MAN1	CG3167 gene product from transcript CG3167-RA	0.012
krz	kurtz	0.012
fbl	fumble	0.012
cv-c	crossveinless c	0.012
Jhe	Juvenile hormone esterase	0.012
Df31	Decondensation factor 31	0.012
crc	cryptocephal	0.012
Snap25	Synapse protein 25	0.011
CG9624	CG9624 gene product from transcript CG9624-RA	0.011
rt	rotated abdomen	0.011
Adar	Adenosine deaminase acting on RNA	0.011
Hsp70Ba	Heat-shock-protein-70Ba	0.011
CG17996	CG17996 gene product from transcript CG17996-RA	0.011
CG4484	CG4484 gene product from transcript CG4484-RA	0.011
park	parkin	0.011
dlp	dally-like	0.011
Eip63F-1	Ecdysone-induced protein 63F 1	0.011
CG10098	CG10098 gene product from transcript CG10098-RA	0.011
CG6623	CG6623 gene product from transcript CG6623-RA	0.011
CG9009	CG9009 gene product from transcript CG9009-RB	0.011
ade3	adenosine 3	0.011
C901	CG1567 gene product from transcript CG1567-RA	0.011
grim	CG4345 gene product from transcript CG4345-RA	0.011
up	upheld	0.011
kermit	CG11546 gene product from transcript CG11546-RB	0.011
Cyp12d1-p	CG30489 gene product from transcript CG30489-RA	0.011
PGRP-LF	Peptidoglycan recognition protein LF	0.011
bip1	CG7574 gene product from transcript CG7574-RA	0.011
TwdlE	TweedleE	0.011
CG12001	CG12001 gene product from transcript CG12001-RA	0.011
FK506-bp1	FK506-binding protein 1	0.011
Pcmt	Protein-L-isoaspartate (D-aspartate) O-methyltransferase	0.011
ena	enabled	0.011
Pgk	Phosphoglycerate kinase	0.011
CG6084	CG6084 gene product from transcript CG6084-RB	0.010	Rat
CG31864	CG31864 gene product from transcript CG31864-RA	0.010
mRpL4	mitochondrial ribosomal protein L4	0.010
cype	cyclope	0.010
prom	prominin	0.010
E23	Early gene at 23	0.010
Ilk	Integrin linked kinase	0.010
Tal	CG2827 gene product from transcript CG2827-RA	0.010
CG3566	CG3566 gene product from transcript CG3566-RB	0.010
rumi	CG31152 gene product from transcript CG31152-RA	0.010
Aats-met	Methionyl-tRNA synthetase	0.010
CG5191	CG5191 gene product from transcript CG5191-RE	0.010