IMP: Integrative Multi-species Prediction

Drosophila melanogaster

31 genes annotated in fly

Multi-species View

actin polymerization or depolymerization

GO:0008154

Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "actin polymerization or depolymerization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "actin polymerization or depolymerization" (in gray)

Name	Description	Probability	Func Analog Organism
chic	chickadee	0.989
ena	enabled	0.943	Mouse
Arp66B	Actin-related protein 66B	0.896	Human Yeast Worm
Arc-p34	CG10954 gene product from transcript CG10954-RA	0.831	Human
katanin-60	katanin 60	0.827
Rac1	CG2248 gene product from transcript CG2248-RA	0.795	Mouse Fly
cpa	capping protein alpha	0.733
Cdc42	CG12530 gene product from transcript CG12530-RA	0.723
par-1	CG8201 gene product from transcript CG8201-RA	0.719
rok	Rho-kinase	0.672	Fly
WASp	CG1520 gene product from transcript CG1520-RA	0.655
bif	bifocal	0.639
Rala	Ras-related protein	0.618
Hem	HEM-protein	0.583	Mouse
mbc	myoblast city	0.549
sqh	spaghetti squash	0.525
Rab11	Rab-protein 11	0.521
trc	tricornered	0.457
twf	twinfilin	0.427
zip	zipper	0.401
Rho1	CG8416 gene product from transcript CG8416-RB	0.376
robo	roundabout	0.376
Mtl	Mig-2-like	0.353	Fly
p120ctn	Adherens junction protein p120	0.347
spir	spire	0.336
cindr	CIN85 and CD2AP orthologue	0.331
baz	bazooka	0.295
egh	egghead	0.282
numb	CG3779 gene product from transcript CG3779-RB	0.281
Vrp1	Verprolin 1	0.279
usp	ultraspiracle	0.273
spas	spastin	0.250
not	non-stop	0.249
CkIIbeta	Casein kinase II beta subunit	0.248
dsh	dishevelled	0.246
pum	pumilio	0.240
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.239
S6k	RPS6-p70-protein kinase	0.238
alpha-Adaptin	CG4260 gene product from transcript CG4260-RA	0.220
cta	concertina	0.217
flr	flare	0.216
Sos	Son of sevenless	0.215
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.210
Sop2	Suppressor of profilin 2	0.208	Human Yeast
Sra-1	specifically Rac1-associated protein 1	0.200
gig	gigas	0.195
shot	short stop	0.193
sls	sallimus	0.190
Akt1	CG4006 gene product from transcript CG4006-RA	0.188
Actn	alpha actinin	0.185
Mical	Molecule interacting with CasL	0.184
ttk	tramtrack	0.183
par-6	CG5884 gene product from transcript CG5884-RA	0.179
cora	coracle	0.177
RhoGAP92B	CG4755 gene product from transcript CG4755-RA	0.176
G-oalpha47A	G protein oalpha 47A	0.172
Dap160	Dynamin associated protein 160	0.168
Prm	Paramyosin	0.164
Arp14D	Actin-related protein 14D	0.153	Human Yeast Worm
trio	CG18214 gene product from transcript CG18214-RA	0.144	Worm
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.138
Arf51F	ADP ribosylation factor 51F	0.133	Human
plexA	plexin A	0.130
Src64B	Src oncogene at 64B	0.129
sns	sticks and stones	0.127	Mouse
Pak3	CG14895 gene product from transcript CG14895-RA	0.125
wdb	widerborst	0.124
hts	hu li tai shao	0.115	Human
msn	misshapen	0.112
egl	egalitarian	0.110
RhoGAPp190	CG32555 gene product from transcript CG32555-RB	0.107
Ten-m	Tenascin major	0.105
fra	frazzled	0.105
hep	hemipterous	0.101
Abi	Abelson interacting protein	0.097
Arc-p20	CG5972 gene product from transcript CG5972-RA	0.097
Pen	Pendulin	0.093
lea	leak	0.093
cpb	capping protein beta	0.092
lqfR	liquid facets-Related	0.092
DAAM	Dishevelled Associated Activator of Morphogenesis	0.091
Ptp69D	Protein tyrosine phosphatase 69D	0.087
Cortactin	CG3637 gene product from transcript CG3637-RA	0.087
sn	singed	0.086
Rab7	Rab-protein 7	0.084
crb	crumbs	0.084
HSPC300	CG30173 gene product from transcript CG30173-RA	0.083
bsk	basket	0.080
Mlc-c	Myosin light chain cytoplasmic	0.080
Brca2	Breast cancer 2, early onset homolog	0.080
Mrtf	Myocardin-related transcription factor	0.078
sec5	CG8843 gene product from transcript CG8843-RA	0.072
kirre	kin of irre	0.071
mys	myospheroid	0.071
wun	wunen	0.071
Caps	Calcium activated protein for secretion	0.070
Mob2	CG11711 gene product from transcript CG11711-RC	0.070
rap	retina aberrant in pattern	0.070
cnc	cap-n-collar	0.069
tomosyn	CG17762 gene product from transcript CG17762-RB	0.069
Mlc2	Myosin light chain 2	0.068
futsch	CG34387 gene product from transcript CG34387-RC	0.066
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.063
Pk61C	Protein kinase 61C	0.062
robo3	CG5423 gene product from transcript CG5423-RA	0.061
Hph	HIF prolyl hydroxylase	0.061
Rac2	CG8556 gene product from transcript CG8556-RA	0.061	Mouse Fly
how	held out wings	0.061
CG32556	CG32556 gene product from transcript CG32556-RB	0.059
Dlic	Dynein light intermediate chain	0.059
Cip4	CG15015 gene product from transcript CG15015-RA	0.059
didum	dilute class unconventional myosin	0.058
fry	furry	0.058
Vang	Van Gogh	0.058
Chc	Clathrin heavy chain	0.057
beta-Spec	beta Spectrin	0.056
CrebB-17A	Cyclic-AMP response element binding protein B at 17A	0.054
Dcr-2	Dicer-2	0.054
rhea	CG6831 gene product from transcript CG6831-RA	0.054
kuz	kuzbanian	0.053
Pak	PAK-kinase	0.052	Human
otk	off-track	0.052
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.052
CG8578	CG8578 gene product from transcript CG8578-RA	0.049
da	daughterless	0.048
X11L	CG5675 gene product from transcript CG5675-RB	0.046
Syx1A	Syntaxin 1A	0.046
kel	kelch	0.044
mts	microtubule star	0.043
spen	split ends	0.043
sano	serrano	0.042
CG5447	CG5447 gene product from transcript CG5447-RA	0.042
Act57B	Actin 57B	0.041
Rab6	Rab-protein 6	0.040
Aplip1	APP-like protein interacting protein 1	0.040
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.039
pod1	CG4532 gene product from transcript CG4532-RF	0.039	Human
Jra	Jun-related antigen	0.038
Pink1	PTEN-induced putative kinase 1	0.038
pigs	pickled eggs	0.038
Lis-1	Lissencephaly-1	0.037
luna	CG33473 gene product from transcript CG33473-RB	0.037
up	upheld	0.037
in	inturned	0.037
p16-ARC	CG9881 gene product from transcript CG9881-RA	0.037
S6kII	RPS6-protein kinase-II	0.037
lilli	lilliputian	0.036
aop	anterior open	0.036
Zasp66	Z band alternatively spliced PDZ-motif protein 66	0.036
CG3563	CG3563 gene product from transcript CG3563-RA	0.036
exba	extra bases	0.036
CG31224	CG31224 gene product from transcript CG31224-RA	0.035
CG17082	CG17082 gene product from transcript CG17082-RD	0.035
bchs	blue cheese	0.035
sty	sprouty	0.034
rut	rutabaga	0.034
alpha-Spec	alpha Spectrin	0.034
stan	starry night	0.034
Dad	Daughters against dpp	0.033
Act5C	Actin 5C	0.033
stau	staufen	0.033
Abl	Abl tyrosine kinase	0.032	Rat
unc-104	CG8566 gene product from transcript CG8566-RB	0.032
srp	serpent	0.032
tay	tay bridge	0.031
dx	deltex	0.031
eff	effete	0.030
Nrg	Neuroglian	0.030
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.030
scb	scab	0.030
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.029
vav	CG7893 gene product from transcript CG7893-RB	0.029
babo	baboon	0.029
CG31352	CG31352 gene product from transcript CG31352-RA	0.029
btl	breathless	0.028
Rya-r44F	Ryanodine receptor 44F	0.028
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.028
BicD	Bicaudal D	0.027
drpr	draper	0.027
jim	CG11352 gene product from transcript CG11352-RB	0.027
Sdc	Syndecan	0.026
glo	glorund	0.026
pyd	polychaetoid	0.026
blow	blown fuse	0.025
Wnt5	Wnt oncogene analog 5	0.025
CG12112	CG12112 gene product from transcript CG12112-RA	0.025
hbs	hibris	0.025	Mouse
Tm2	Tropomyosin 2	0.025	Rat Worm
Fas3	Fasciclin 3	0.025
Top3beta	Topoisomerase 3beta	0.024
CanB2	Calcineurin B2	0.024
jar	jaguar	0.024
coro	CG9446 gene product from transcript CG9446-RC	0.024	Mouse
Eps-15	Epidermal growth factor receptor pathway substrate clone 15	0.024
endoA	endophilin A	0.024
NetB	Netrin-B	0.024
dgo	diego	0.024
Tsc1	CG6147 gene product from transcript CG6147-RA	0.023
Pfrx	6-phosphofructo-2-kinase	0.023
Rab23	CG2108 gene product from transcript CG2108-RA	0.023
CG10641	CG10641 gene product from transcript CG10641-RA	0.023
Atg1	Autophagy-specific gene 1	0.022
zfh1	Zn finger homeodomain 1	0.022
rols	rolling pebbles	0.022
Fs	Follistatin	0.022
rst	roughest	0.022	Mouse
dock	dreadlocks	0.022	Human Mouse
cdi	center divider	0.021
Pabp2	CG2163 gene product from transcript CG2163-RA	0.021
p130CAS	CG1212 gene product from transcript CG1212-RA	0.021
CadN	Cadherin-N	0.021
kermit	CG11546 gene product from transcript CG11546-RB	0.021
sw	short wing	0.021
kay	kayak	0.021
CG1486	CG1486 gene product from transcript CG1486-RA	0.020
Lasp	CG3849 gene product from transcript CG3849-RB	0.020
stai	stathmin	0.020
Ced-12	CG5336 gene product from transcript CG5336-RA	0.020
LanA	Laminin A	0.020
CG1021	CG1021 gene product from transcript CG1021-RE	0.020
lmd	lame duck	0.020
Fas2	Fasciclin 2	0.020
qm	quemao	0.020
jeb	jelly belly	0.020
caz	cabeza	0.020
Tak1	TGF-beta activated kinase 1	0.020
mbt	mushroom bodies tiny	0.020
mmy	mummy	0.019
rl	rolled	0.019
Rab5	Rab-protein 5	0.019
CG8765	CG8765 gene product from transcript CG8765-RA	0.019
Hip14	Huntingtin-interacting protein 14	0.019
wit	wishful thinking	0.019
Su(dx)	Suppressor of deltex	0.019
synaptogyrin	CG10808 gene product from transcript CG10808-RA	0.019
drl	derailed	0.019
ik2	IkappaB kinase-like 2	0.019
Ppt1	Palmitoyl-protein thioesterase 1	0.019
trn	tartan	0.019
capu	cappuccino	0.019
rictor	rapamycin-insensitive companion of Tor	0.019	Mouse
sec6	CG5341 gene product from transcript CG5341-RA	0.018
RhoGEF2	CG9635 gene product from transcript CG9635-RF	0.018
Lim3	CG10699 gene product from transcript CG10699-RB	0.018
Act88F	Actin 88F	0.018
foxo	forkhead box, sub-group O	0.018
Peb	Protein ejaculatory bulb	0.018
cno	canoe	0.018
tth	toothrin	0.018
Marf	Mitochondrial assembly regulatory factor	0.018
CkIalpha	Casein kinase Ialpha	0.018
CG10083	CG10083 gene product from transcript CG10083-RA	0.018
neur	neuralized	0.017
raptor	CG4320 gene product from transcript CG4320-RA	0.017
Ric	Ras which interacts with Calmodulin	0.017
Tao-1	CG14217 gene product from transcript CG14217-RF	0.017
l(2)gl	lethal (2) giant larvae	0.017
Tig	Tiggrin	0.017
osk	oskar	0.017
POSH	Plenty of SH3s	0.017
hipk	homeodomain interacting protein kinase	0.017
MED24	Mediator complex subunit 24	0.017
CG3371	CG3371 gene product from transcript CG3371-RA	0.017
grh	grainy head	0.017
CG11299	CG11299 gene product from transcript CG11299-RA	0.017
Pdp1	PAR-domain protein 1	0.017
tud	tudor	0.017
Sox14	Sox box protein 14	0.017
CG17556	CG17556 gene product from transcript CG17556-RA	0.017
Gem3	Gemin3	0.017
CHKov1	CG10618 gene product from transcript CG10618-RB	0.017
sav	salvador	0.016
Fhos	CG42610 gene product from transcript CG42610-RC	0.016
tipE	temperature-induced paralytic E	0.016
Shc	SHC-adaptor protein	0.016
Mlc1	Myosin alkali light chain 1	0.016
cher	cheerio	0.016
klg	klingon	0.016
spdo	sanpodo	0.016
raw	CG12437 gene product from transcript CG12437-RB	0.016
CG6051	CG6051 gene product from transcript CG6051-RB	0.016
Dscam	Down syndrome cell adhesion molecule	0.016
Gga	CG3002 gene product from transcript CG3002-RB	0.016
synj	synaptojanin	0.016
Pp4-19C	Protein phosphatase 19C	0.015
tmod	tropomodulin	0.015	Worm
Rab2	Rab-protein 2	0.015
Sin1	SAPK-interacting protein 1	0.015
Act87E	Actin 87E	0.015
Mkp3	Mitogen-activated protein kinase phosphatase 3	0.015
lola	longitudinals lacking	0.015
aPKC	atypical protein kinase C	0.015
pex2	peroxin 2	0.015
Scgdelta	Sarcoglycan delta	0.014
fas	faint sausage	0.014
Gos28	CG7700 gene product from transcript CG7700-RA	0.014
RhoGAP71E	CG32149 gene product from transcript CG32149-RD	0.014
CG3638	CG3638 gene product from transcript CG3638-RE	0.014
Amph	Amphiphysin	0.014
CG16791	CG16791 gene product from transcript CG16791-RA	0.014
chico	CG5686 gene product from transcript CG5686-RB	0.014
LIMK1	LIM-kinase1	0.014
bt	bent	0.014
simj	simjang	0.014
flw	flapwing	0.014
ham	hamlet	0.014
Nmnat	Nicotinamide mononucleotide adenylyltransferase	0.014
gb	genderblind	0.014
CG14442	CG14442 gene product from transcript CG14442-RB	0.014
RanBPM	Ran-binding protein M	0.014
Pde8	Phosphodiesterase 8	0.014
Mp20	Muscle protein 20	0.014
CG31146	CG31146 gene product from transcript CG31146-RD	0.014
Pp2B-14D	Protein phosphatase 2B at 14D	0.013
Uba1	Ubiquitin activating enzyme 1	0.013
spz	spatzle	0.013
wupA	wings up A	0.013
Vinc	Vinculin	0.013
pcx	pecanex	0.013
Mkk4	MAP kinase kinase 4	0.013
SdhA	Succinate dehydrogenase A	0.013
CG5857	CG5857 gene product from transcript CG5857-RA	0.013
CG33095	CG33095 gene product from transcript CG33095-RB	0.013
CG3573	CG3573 gene product from transcript CG3573-RA	0.013
CG12029	CG12029 gene product from transcript CG12029-RB	0.013
mfrn	mitoferrin	0.013
mus308	mutagen-sensitive 308	0.013
opa1-like	optic atrophy 1-like	0.013
puc	puckered	0.013
Miro	Mitochondrial Rho	0.013
htl	heartless	0.013
Deaf1	Deformed epidermal autoregulatory factor-1	0.013
mwh	multiple wing hairs	0.013
HmgD	High mobility group protein D	0.013
TSG101	tumor suppressor protein 101	0.012
dac	dachshund	0.012
CG9650	CG9650 gene product from transcript CG9650-RG	0.012
Apc2	Adenomatous polyposis coli tumor suppressor homolog 2	0.012
drosha	CG8730 gene product from transcript CG8730-RA	0.012
capt	capulet	0.012
wdp	windpipe	0.012
kat80	katanin 80	0.012
eve	even skipped	0.012
CG1129	CG1129 gene product from transcript CG1129-RC	0.012
dei	delilah	0.012
frtz	fritz	0.012
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.012
Rpt3	CG16916 gene product from transcript CG16916-RA	0.012
Mlp84B	Muscle LIM protein at 84B	0.012
yata	CG1973 gene product from transcript CG1973-RA	0.012
sec23	CG1250 gene product from transcript CG1250-RA	0.012
CG10260	CG10260 gene product from transcript CG10260-RB	0.012
sds22	CG5851 gene product from transcript CG5851-RA	0.012
Past1	Putative Achaete Scute Target 1	0.012
E(spl)	Enhancer of split	0.012
kat-60L1	katanin p60-like 1	0.012
Rbsn-5	Rabenosyn-5	0.012
Atg2	Autophagy-specific gene 2	0.012
step	steppke	0.012
lace	CG4162 gene product from transcript CG4162-RA	0.012
shd	shade	0.011
Ca-alpha1D	Ca[2+]-channel protein alpha[[1]] subunit D	0.011
CG42389	CG42389 gene product from transcript CG42389-RE	0.011
Atpalpha	Na pump alpha subunit	0.011
Appl	beta amyloid protein precursor-like	0.011
Tom34	Translocase of outer membrane 34	0.011
CG31048	CG31048 gene product from transcript CG31048-RB	0.011
Msi	Male-specific insect derived growth factor	0.011
nerfin-1	nervous fingers 1	0.011
tau	CG31057 gene product from transcript CG31057-RA	0.011
cbt	cabut	0.011
HspB8	CG14207 gene product from transcript CG14207-RB	0.011
zormin	CG33484 gene product from transcript CG33484-RC	0.011
CG31687	CG31687 gene product from transcript CG31687-RA	0.011
Trim9	CG31721 gene product from transcript CG31721-RB	0.011
CG10068	CG10068 gene product from transcript CG10068-RA	0.011
mus201	mutagen-sensitive 201	0.011
e(y)1	enhancer of yellow 1	0.011
chrb	charybde	0.011
sec71	CG7578 gene product from transcript CG7578-RA	0.011
Ac76E	Adenylyl cyclase 76E	0.011
exo84	CG6095 gene product from transcript CG6095-RA	0.011
CG3038	CG3038 gene product from transcript CG3038-RB	0.011
rho-7	rhomboid-7	0.011
RN-tre	tre oncogene-related protein	0.011
Nedd4	CG42279 gene product from transcript CG42279-RJ	0.011
CBP	sarcoplasmic calcium-binding protein	0.011
Pka-C3	cAMP-dependent protein kinase 3	0.011
Esyt2	CG6643 gene product from transcript CG6643-RA	0.011
rin	rasputin	0.011
l(1)10Bb	lethal (1) 10Bb	0.011
ndl	nudel	0.011
ens	ensconsin	0.011
mGluRA	metabotropic glutamate receptor	0.011
pfk	piefke	0.011
poe	purity of essence	0.011
lig	lingerer	0.011
PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	0.011
tutl	turtle	0.011
MESK2	Misexpression suppressor of KSR 2	0.010
trr	trithorax-related	0.010
CG2709	CG2709 gene product from transcript CG2709-RA	0.010
pll	pelle	0.010
VhaM9.7-1	CG11589 gene product from transcript CG11589-RA	0.010
Letm1	CG4589 gene product from transcript CG4589-RB	0.010
Ercc1	CG10215 gene product from transcript CG10215-RA	0.010
Alk	CG8250 gene product from transcript CG8250-RA	0.010
shg	shotgun	0.010
ck	crinkled	0.010
CG9053	CG9053 gene product from transcript CG9053-RA	0.010
vps2	CG14542 gene product from transcript CG14542-RA	0.010
scu	scully	0.010
eIF4G2	eukaryotic translation initiation factor 4G2	0.010
Patj	CG12021 gene product from transcript CG12021-RC	0.010
Synd	Syndapin	0.010
pk	prickle	0.010
Apc	APC-like	0.010
myoglianin	CG1838 gene product from transcript CG1838-RD	0.010
CG13917	CG13917 gene product from transcript CG13917-RB	0.010
oys	oysgedart	0.010
Dsk	Drosulfakinin	0.010
SoxN	SoxNeuro	0.010