IMP: Integrative Multi-species Prediction

Drosophila melanogaster

22 genes annotated in fly

positive regulation of secretion

Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of secretion"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Mekk1	CG7717 gene product from transcript CG7717-RB	0.805
hth	homothorax	0.705
hep	hemipterous	0.690
eca	eclair	0.499
dlg1	discs large 1	0.376
par-1	CG8201 gene product from transcript CG8201-RA	0.350
wls	wntless	0.339
unc-13	CG2999 gene product from transcript CG2999-RA	0.338	Mouse Rat
rtGEF	rho-type guanine exchange factor	0.331
Rac1	CG2248 gene product from transcript CG2248-RA	0.327
p24-1	p24-related-1	0.309
GluRIIA	Glutamate receptor IIA	0.250
dys	dysfusion	0.243
Smg1	CG32743 gene product from transcript CG32743-RA	0.231
lqf	liquid facets	0.231
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.209
Nrx-1	Neurexin 1	0.183
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.181	Human
brp	bruchpilot	0.175
Khc-73	Kinesin-73	0.170	Fly
sgl	sugarless	0.159
neuroligin	CG13772 gene product from transcript CG13772-RA	0.159	Mouse Rat
Rab7	Rab-protein 7	0.155	Human
Src42A	Src oncogene at 42A	0.148
CanA1	Calcineurin A1	0.147	Mouse Rat
wun	wunen	0.136
bai	baiser	0.128
drk	downstream of receptor kinase	0.123
Gyc76C	Guanylyl cyclase at 76C	0.122
HDAC6	CG6170 gene product from transcript CG6170-RA	0.121
Moe	Moesin	0.118
p24-2	p24-related-2	0.118	Fly
Frq2	Frequenin 2	0.112	Rat
Ank2	Ankyrin 2	0.111
Pp2B-14D	Protein phosphatase 2B at 14D	0.102	Mouse Rat
grp	grapes	0.102
CG34139	CG34139 gene product from transcript CG34139-RD	0.092	Rat
Osbp	Oxysterol binding protein	0.089
CG11317	CG11317 gene product from transcript CG11317-RA	0.084
sfl	sulfateless	0.082
katanin-60	katanin 60	0.081
cher	cheerio	0.081
PRL-1	CG4993 gene product from transcript CG4993-RB	0.080
Hs6st	Heparan sulfate 6-O-sulfotransferase	0.080
Rac2	CG8556 gene product from transcript CG8556-RA	0.077
stnB	stoned B	0.076
G-oalpha47A	G protein oalpha 47A	0.073
Pk61C	Protein kinase 61C	0.072
vkg	viking	0.072	Worm
btl	breathless	0.070
CG12187	CG12187 gene product from transcript CG12187-RA	0.069
myoglianin	CG1838 gene product from transcript CG1838-RD	0.068
AdoR	Adenosine receptor	0.061
wit	wishful thinking	0.060
lap	like-AP180	0.060
sqh	spaghetti squash	0.059
Catsup	Catecholamines up	0.059
fz2	frizzled 2	0.059
Ork1	Open rectifier K[+] channel 1	0.058
Tl	Toll	0.057
SdhA	Succinate dehydrogenase A	0.056
Eip63F-1	Ecdysone-induced protein 63F 1	0.056
Hnf4	Hepatocyte nuclear factor 4	0.056
RASSF8	CG5053 gene product from transcript CG5053-RA	0.056
Tango1	Transport and Golgi organization 1	0.055
Rab5	Rab-protein 5	0.055	Human
CG10103	CG10103 gene product from transcript CG10103-RA	0.054
Duox	Dual oxidase	0.054
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.053
pnt	pointed	0.052
Ace	Acetylcholine esterase	0.052
Dat	Dopamine N acetyltransferase	0.051
Rop	Ras opposite	0.050	Mouse Rat Worm
CG6191	CG6191 gene product from transcript CG6191-RA	0.049
Rab3	Rab-protein 3	0.049	Human
deltaCOP	delta-coatomer protein	0.049
stj	straightjacket	0.048
usp	ultraspiracle	0.048
bsk	basket	0.047	Rat
Rab6	Rab-protein 6	0.047
mth	methuselah	0.047
Nrt	Neurotactin	0.047
endoA	endophilin A	0.045
trp	transient receptor potential	0.045
fkh	fork head	0.044
gcm	glial cells missing	0.044
ird1	immune response deficient 1	0.044
BG4	CG12297 gene product from transcript CG12297-RA	0.043
Rab2	Rab-protein 2	0.041
faf	fat facets	0.041
ZIP1	Zinc/iron regulated transporter-related protein 1	0.039
stmA	stambha A	0.038
CG34400	CG34400 gene product from transcript CG34400-RD	0.038
Snap25	Synapse protein 25	0.037
Tequila	CG4821 gene product from transcript CG4821-RE	0.037
cpx	complexin	0.036
Syt1	Synaptotagmin 1	0.036	Rat
mbc	myoblast city	0.035
pgant3	polypeptide GalNAc transferase 3	0.035	Fly
sec63	CG8583 gene product from transcript CG8583-RA	0.035
capt	capulet	0.034
CycJ	Cyclin J	0.034
Papss	PAPS synthetase	0.034
Tab2	TAK1-associated binding protein 2	0.034
rhea	CG6831 gene product from transcript CG6831-RA	0.033
nudE	CG8104 gene product from transcript CG8104-RB	0.033
heix	heixuedian	0.033
Pis	Phosphatidylinositol synthase	0.032
Mo25	CG4083 gene product from transcript CG4083-RA	0.032
nej	nejire	0.032
trio	CG18214 gene product from transcript CG18214-RA	0.032
how	held out wings	0.032
CG8602	CG8602 gene product from transcript CG8602-RA	0.031
CG30069	CG30069 gene product from transcript CG30069-RA	0.031
egr	eiger	0.031	Mouse
CG5727	CG5727 gene product from transcript CG5727-RA	0.031
step	steppke	0.030
grn	grain	0.030
conv	convoluted	0.029
gho	ghost	0.029
CDase	Ceramidase	0.029
Rim	CG33547 gene product from transcript CG33547-RB	0.028
Abl	Abl tyrosine kinase	0.028	Mouse
Tsf2	Transferrin 2	0.028
comt	comatose	0.027
Pgm	Phosphogluconate mutase	0.027
zfh1	Zn finger homeodomain 1	0.026
Spn	Spinophilin	0.026
Stam	Signal transducing adaptor molecule	0.026	Human
wgn	wengen	0.025
Gadd45	CG11086 gene product from transcript CG11086-RA	0.025
shn	schnurri	0.024
cv-c	crossveinless c	0.024
Imp	IGF-II mRNA-binding protein	0.024
CG1129	CG1129 gene product from transcript CG1129-RC	0.024
sll	slalom	0.024
Chc	Clathrin heavy chain	0.024
vps24	Charged multivesicular body protein 3	0.023
CG9053	CG9053 gene product from transcript CG9053-RA	0.023
SAK	Sak kinase	0.023
CG7813	CG7813 gene product from transcript CG7813-RA	0.023
Vhl	von Hippel-Lindau	0.023
Rab35	CG9575 gene product from transcript CG9575-RA	0.023
Myd88	CG2078 gene product from transcript CG2078-RA	0.023
Tis11	Tis11 homolog	0.023
Ric	Ras which interacts with Calmodulin	0.022
ric8a	CG15797 gene product from transcript CG15797-RA	0.022
Sec61alpha	CG9539 gene product from transcript CG9539-RA	0.022
hiw	highwire	0.022
Pka-R2	cAMP-dependent protein kinase R2	0.022
Vha100-1	CG1709 gene product from transcript CG1709-RF	0.022
Syt4	Synaptotagmin 4	0.021
dnr1	defense repressor 1	0.021
TRAM	CG11642 gene product from transcript CG11642-RB	0.021
ru	roughoid	0.021
mtt	mangetout	0.021
bnl	branchless	0.021
CG33558	CG33558 gene product from transcript CG33558-RG	0.021
cdi	center divider	0.021
shot	short stop	0.020
pdm3	pou domain motif 3	0.020
cact	cactus	0.020
lva	lava lamp	0.020
shrb	shrub	0.020
mav	maverick	0.020
park	parkin	0.020
laza	lazaro	0.020
wb	wing blister	0.019
Pkc98E	Protein C kinase 98E	0.019	Mouse
CG4552	CG4552 gene product from transcript CG4552-RA	0.019
trpml	transient receptor potential mucolipin	0.019
CG32810	CG32810 gene product from transcript CG32810-RB	0.019
Atpalpha	Na pump alpha subunit	0.019
PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	0.019
dlp	dally-like	0.019
gry	gryzun	0.019
Syn2	Syntrophin-like 2	0.019
tinc	tincar	0.018
Gfat2	Glutamine:fructose-6-phosphate aminotransferase 2	0.018
slo	slowpoke	0.018
pck	pickel	0.018
CG6490	CG6490 gene product from transcript CG6490-RB	0.018
Tfb5	CG42373 gene product from transcript CG42373-RB	0.018
rho-5	rhomboid-5	0.018
Mmp2	Matrix metalloproteinase 2	0.018
onecut	CG1922 gene product from transcript CG1922-RA	0.018
Alk	CG8250 gene product from transcript CG8250-RA	0.018
Xe7	CG2179 gene product from transcript CG2179-RA	0.018
oaf	out at first	0.018
cdc14	CG7134 gene product from transcript CG7134-RB	0.018
S6k	RPS6-p70-protein kinase	0.018
Zw	Zwischenferment	0.018
CG7656	CG7656 gene product from transcript CG7656-RA	0.017
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.017
Tbh	Tyramine beta hydroxylase	0.017
cup	CG11181 gene product from transcript CG11181-RB	0.017
jar	jaguar	0.017
CG32354	CG32354 gene product from transcript CG32354-RA	0.017
Unc-76	CG3981 gene product from transcript CG3981-RB	0.017
tin	tinman	0.017
vvl	ventral veins lacking	0.017
spen	split ends	0.017
klu	klumpfuss	0.017
Cg25C	Collagen type IV	0.017	Worm
Fkbp13	CG9847 gene product from transcript CG9847-RC	0.017
Sox21b	CG32139 gene product from transcript CG32139-RA	0.016
CG30409	CG30409 gene product from transcript CG30409-RA	0.016
Dlic	Dynein light intermediate chain	0.016
Pi3K68D	Phosphotidylinositol 3 kinase 68D	0.016
so	sine oculis	0.016
CG12084	CG12084 gene product from transcript CG12084-RA	0.016
CG12001	CG12001 gene product from transcript CG12001-RA	0.016
ry	rosy	0.016
Dad	Daughters against dpp	0.016
rig	rigor mortis	0.016
drd	drop dead	0.016
cenG1A	centaurin gamma 1A	0.016
CG31146	CG31146 gene product from transcript CG31146-RD	0.016	Rat
Adgf-A	Adenosine deaminase-related growth factor A	0.016
sec71	CG7578 gene product from transcript CG7578-RA	0.016
aux	auxillin	0.015
Cyt-c-d	Cytochrome c distal	0.015
inaD	inactivation no afterpotential D	0.015
alpha-Est7	alpha-Esterase-7	0.015
Akt1	CG4006 gene product from transcript CG4006-RA	0.015
cindr	CIN85 and CD2AP orthologue	0.015
wnd	wallenda	0.015
Vmat	Vesicular monoamine transporter	0.015
na	narrow abdomen	0.015
Mob4	CG3403 gene product from transcript CG3403-RA	0.015
Wnt4	Wnt oncogene analog 4	0.015
gfA	giant fibre A	0.015
CG12026	CG12026 gene product from transcript CG12026-RB	0.015
AP-47	CG9388 gene product from transcript CG9388-RA	0.015
CG14234	CG14234 gene product from transcript CG14234-RA	0.015
SoxN	SoxNeuro	0.015
CG9132	CG9132 gene product from transcript CG9132-RA	0.015
garz	gartenzwerg	0.015
rno	rhinoceros	0.014
Syx1A	Syntaxin 1A	0.014	Mouse Rat
CG17233	CG17233 gene product from transcript CG17233-RA	0.014
fd85E	forkhead domain 85E	0.014
l(1)G0320	lethal (1) G0320	0.014
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.014
CG13409	CG13409 gene product from transcript CG13409-RA	0.014
Toll-6	CG7250 gene product from transcript CG7250-RA	0.014
drm	drumstick	0.014
ro	rough	0.014
CG5850	CG5850 gene product from transcript CG5850-RC	0.014
Gr28b	Gustatory receptor 28b	0.014
Apc2	Adenomatous polyposis coli tumor suppressor homolog 2	0.014
mun	munin	0.013
CG14764	CG14764 gene product from transcript CG14764-RA	0.013
grk	gurken	0.013
VGlut	Vesicular glutamate transporter	0.013
byn	brachyenteron	0.013
sec6	CG5341 gene product from transcript CG5341-RA	0.013
Past1	Putative Achaete Scute Target 1	0.013
sinu	sinuous	0.013
Patr-1	Protein associated with topo II related - 1	0.013
egl	egalitarian	0.013
Syn1	Syntrophin-like 1	0.013
Oli	Olig family	0.013
CG42672	CG42672 gene product from transcript CG42672-RD	0.013
fusl	fuseless	0.013
CHMP2B	Charged multivesicular body protein 2b	0.013
Galpha49B	G protein alpha49B	0.013	Worm
Ho	Heme oxygenase	0.013
Wnt2	Wnt oncogene analog 2	0.013
Msi	Male-specific insect derived growth factor	0.012
cad	caudal	0.012
Nrx-IV	Neurexin IV	0.012
GluRIIB	Glutamate receptor IIB	0.012
CanB	Calcineurin B	0.012
sif	still life	0.012
CG2918	CG2918 gene product from transcript CG2918-RA	0.012
RhoGAP92B	CG4755 gene product from transcript CG4755-RA	0.012
sog	short gastrulation	0.012
e	ebony	0.012
CG8500	CG8500 gene product from transcript CG8500-RA	0.012
Ppat-Dpck	Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase	0.012
blot	bloated tubules	0.012
jeb	jelly belly	0.012
CG33960	CG33960 gene product from transcript CG33960-RB	0.012
Smg5	CG8954 gene product from transcript CG8954-RA	0.012
pum	pumilio	0.012
nAcRalpha-7E	nicotinic Acetylcholine Receptor alpha 7E	0.012
elB	elbow B	0.012
CG4194	CG4194 gene product from transcript CG4194-RA	0.012
Ipp	Inositol polyphosphate 1-phosphatase	0.012
Ras64B	Ras oncogene at 64B	0.012
Lsd-2	Lipid storage droplet-2	0.012
synj	synaptojanin	0.012	Worm
Ilp4	Insulin-like peptide 4	0.012
tai	taiman	0.012
Pde8	Phosphodiesterase 8	0.012
mmy	mummy	0.012
Atf-2	Activating transcription factor-2	0.012
neb	nebbish	0.012	Fly
CHOp24	CG3564 gene product from transcript CG3564-RA	0.012
Gmd	GDP-mannose 4,6-dehydratase	0.011
Spn4	Serine protease inhibitor 4	0.011
CG12773	CG12773 gene product from transcript CG12773-RA	0.011
itp	ion transport peptide	0.011
yata	CG1973 gene product from transcript CG1973-RA	0.011
Eaf	ELL-associated factor	0.011
CG31108	CG31108 gene product from transcript CG31108-RA	0.011
Pka-C1	cAMP-dependent protein kinase 1	0.011
ventrally-expressed-protein-D	CG33200 gene product from transcript CG33200-RA	0.011
VAChT	CG32848 gene product from transcript CG32848-RA	0.011
Syn	Synapsin	0.011
CG6406	CG6406 gene product from transcript CG6406-RA	0.011
CG16926	CG16926 gene product from transcript CG16926-RA	0.011
Syt7	CG2381 gene product from transcript CG2381-RB	0.011	Rat
slbo	slow border cells	0.011
Akap200	A kinase anchor protein 200	0.011
ppk16	pickpocket 16	0.011
syd	sunday driver	0.011
Gld	Glucose dehydrogenase	0.011
shakB	shaking B	0.011
ct	cut	0.011
CG8214	CG8214 gene product from transcript CG8214-RA	0.011
CG3493	CG3493 gene product from transcript CG3493-RA	0.011
CG12470	CG12470 gene product from transcript CG12470-RA	0.011
NPFR1	neuropeptide F receptor	0.011
CG17922	CG17922 gene product from transcript CG17922-RA	0.011
ec	echinus	0.010
toy	twin of eyeless	0.010	Rat
CG14168	CG14168 gene product from transcript CG14168-RA	0.010
CG1371	CG1371 gene product from transcript CG1371-RA	0.010
amos	absent MD neurons and olfactory sensilla	0.010
CG12576	CG12576 gene product from transcript CG12576-RA	0.010
tan	tantalus	0.010
Arp14D	Actin-related protein 14D	0.010
CG31029	CG31029 gene product from transcript CG31029-RA	0.010
CG12428	CG12428 gene product from transcript CG12428-RB	0.010
Rel	Relish	0.010
CG11362	CG11362 gene product from transcript CG11362-RA	0.010
Mpk2	CG5475 gene product from transcript CG5475-RB	0.010
CG34376	CG34376 gene product from transcript CG34376-RB	0.010
stck	steamer duck	0.010
l(3)76BDm	lethal (3) 76BDm	0.010
Pli	Pellino	0.010
CG13031	CG13031 gene product from transcript CG13031-RA	0.010
pdfr	PDF receptor	0.010
Cul-5	Cullin-5	0.010
CG1041	CG1041 gene product from transcript CG1041-RA	0.010