IMP: Integrative Multi-species Prediction

Drosophila melanogaster

24 genes annotated in fly

response to reactive oxygen species

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to reactive oxygen species"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "response to reactive oxygen species" (in gray)

Name	Description	Probability	Func Analog Organism
Sod2	Superoxide dismutase 2 (Mn)	0.989	Mouse Worm
Prx5	Peroxiredoxin 5	0.965	Human
Sod	Superoxide dismutase	0.951
EcR	Ecdysone receptor	0.890
Trx-2	thioredoxin-2	0.673
PHGPx	CG12013 gene product from transcript CG12013-RC	0.543
Gyc-89Db	Guanylyl cyclase at 89Db	0.455
mth	methuselah	0.452
Jafrac1	thioredoxin peroxidase 1	0.366
Gyc-89Da	Guanylyl cyclase at 89Da	0.354
Hsp27	Heat shock protein 27	0.316	Rat
bsk	basket	0.304
Tsp42Ef	Tetraspanin 42Ef	0.278
chico	CG5686 gene product from transcript CG5686-RB	0.272
Hsp26	Heat shock protein 26	0.267	Mouse Rat
Pink1	PTEN-induced putative kinase 1	0.254	Human
NLaz	Neural Lazarillo	0.233
Pten	CG5671 gene product from transcript CG5671-RB	0.221
CG6783	CG6783 gene product from transcript CG6783-RC	0.220
Tpi	Triose phosphate isomerase	0.205
Mpk2	CG5475 gene product from transcript CG5475-RB	0.205
foxo	forkhead box, sub-group O	0.184	Mouse
SdhB	Succinate dehydrogenase B	0.183
LamC	Lamin C	0.180
MTF-1	Metal response element-binding Transcription Factor-1	0.173
CG14686	CG14686 gene product from transcript CG14686-RA	0.173
Aldh	Aldehyde dehydrogenase	0.168
SMC1	CG6057 gene product from transcript CG6057-RA	0.155
park	parkin	0.153
eag	ether a go-go	0.151
CG13890	CG13890 gene product from transcript CG13890-RA	0.150
Hsp68	Heat shock protein 68	0.137
Rac1	CG2248 gene product from transcript CG2248-RA	0.127
Ras85D	Ras oncogene at 85D	0.120
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.119
CG14715	CG14715 gene product from transcript CG14715-RA	0.118
5-HT1A	Serotonin receptor 1A	0.117
Thor	CG8846 gene product from transcript CG8846-RA	0.113
hep	hemipterous	0.108
Cng	Cyclic-nucleotide-gated ion channel protein	0.106
dj-1beta	CG1349 gene product from transcript CG1349-RA	0.104
GluRIIA	Glutamate receptor IIA	0.098
CG15199	CG15199 gene product from transcript CG15199-RA	0.097
Act88F	Actin 88F	0.096
IP3K2	Inositol 1,4,5-triphosphate kinase 2	0.095
Jra	Jun-related antigen	0.094	Rat
tefu	telomere fusion	0.094
Dab	Disabled	0.092
Zw	Zwischenferment	0.090
Hsp22	Heat shock protein 22	0.090	Rat
sev	sevenless	0.087
mas	masquerade	0.085
kst	karst	0.084
l(3)82Fd	CG32464 gene product from transcript CG32464-RR	0.079
NtR	CG6698 gene product from transcript CG6698-RA	0.078
Hsp23	Heat shock protein 23	0.076	Mouse Rat
CG8036	CG8036 gene product from transcript CG8036-RB	0.069
CG6543	CG6543 gene product from transcript CG6543-RA	0.067
Myo31DF	Myosin 31DF	0.066
Src42A	Src oncogene at 42A	0.066
ey	eyeless	0.065
CG30427	CG30427 gene product from transcript CG30427-RC	0.064
dpr	defective proboscis extension response	0.061
Fs(2)Ket	Female sterile (2) Ketel	0.059
sls	sallimus	0.058
mei-41	meiotic 41	0.057
InR	Insulin-like receptor	0.056	Worm
Cat	Catalase	0.054
Smg1	CG32743 gene product from transcript CG32743-RA	0.053
dmt	dalmatian	0.052
CrebB-17A	Cyclic-AMP response element binding protein B at 17A	0.051
Pvr	PDGF- and VEGF-receptor related	0.051	Rat
rdgB	retinal degeneration B	0.050
Vrp1	Verprolin 1	0.048
CG9986	CG9986 gene product from transcript CG9986-RA	0.048
Traf-like	TNF-receptor-associated factor-like	0.048
GLaz	Glial Lazarillo	0.046	Mouse
CG30410	CG30410 gene product from transcript CG30410-RB	0.045
TBPH	CG10327 gene product from transcript CG10327-RC	0.045
VGlut	Vesicular glutamate transporter	0.044
S6k	RPS6-p70-protein kinase	0.044
ph-d	polyhomeotic distal	0.042
CG2199	CG2199 gene product from transcript CG2199-RB	0.042
king-tubby	king tubby	0.041
robo3	CG5423 gene product from transcript CG5423-RA	0.041
cdc2c	CG10498 gene product from transcript CG10498-RC	0.040
AnnX	Annexin X	0.040
cln3	CG5582 gene product from transcript CG5582-RA	0.040
Eip71CD	Ecdysone-induced protein 28/29kD	0.040
debcl	death executioner Bcl-2 homologue	0.039
Rya-r44F	Ryanodine receptor 44F	0.039
Pcmt	Protein-L-isoaspartate (D-aspartate) O-methyltransferase	0.038
CG12001	CG12001 gene product from transcript CG12001-RA	0.038
Prx2540-2	Peroxiredoxin 2540	0.038
syd	sunday driver	0.037
bves	CG32513 gene product from transcript CG32513-RA	0.036
dnr1	defense repressor 1	0.035
p38b	CG7393 gene product from transcript CG7393-RA	0.034
stai	stathmin	0.033
brp	bruchpilot	0.033
tweek	CG42555 gene product from transcript CG42555-RD	0.032
CG11455	CG11455 gene product from transcript CG11455-RB	0.032
aop	anterior open	0.032
Ntf-2	Nuclear transport factor-2	0.032
trpml	transient receptor potential mucolipin	0.032
para	paralytic	0.032
unc-13	CG2999 gene product from transcript CG2999-RA	0.031
Prx2540-1	Peroxiredoxin 2540	0.031
Krn	Keren	0.031
CG13510	CG13510 gene product from transcript CG13510-RA	0.031
Mf	Myofilin	0.030
rpr	reaper	0.030
apt	apontic	0.030
Rab7	Rab-protein 7	0.029
CG42813	CG42813 gene product from transcript CG42813-RA	0.029
l(1)G0230	lethal (1) G0230	0.029
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.029
ERR	estrogen-related receptor	0.029
Pde8	Phosphodiesterase 8	0.028
CG11875	CG11875 gene product from transcript CG11875-RA	0.028
unc-104	CG8566 gene product from transcript CG8566-RB	0.028
Pgk	Phosphoglycerate kinase	0.028
RhoGAP15B	CG4937 gene product from transcript CG4937-RC	0.028
stmA	stambha A	0.028
CG9027	CG9027 gene product from transcript CG9027-RD	0.027
Fmr1	CG6203 gene product from transcript CG6203-RC	0.027
ena	enabled	0.027
CG3638	CG3638 gene product from transcript CG3638-RE	0.027
Ser	Serrate	0.026
kermit	CG11546 gene product from transcript CG11546-RB	0.026
Nlp	Nucleoplasmin	0.026
CG6673	CG6673 gene product from transcript CG6673-RA	0.026
CG18522	CG18522 gene product from transcript CG18522-RA	0.026
Rab5	Rab-protein 5	0.025
obst-A	obstructor-A	0.025
rt	rotated abdomen	0.024
sec10	CG6159 gene product from transcript CG6159-RA	0.024
Gadd45	CG11086 gene product from transcript CG11086-RA	0.024
ari-2	ariadne 2	0.024
Trap1	CG3152 gene product from transcript CG3152-RA	0.024
DJ-1alpha	CG6646 gene product from transcript CG6646-RA	0.024
TrpA1	Transient receptor potential A1	0.023	Mouse
Tis11	Tis11 homolog	0.023
CG7998	CG7998 gene product from transcript CG7998-RA	0.023
Dsor1	Downstream of raf1	0.023
east	enhanced adult sensory threshold	0.023
mol	moladietz	0.023
Cyp301a1	CG8587 gene product from transcript CG8587-RA	0.023
phol	pleiohomeotic like	0.022
dia	diaphanous	0.022
fzy	fizzy	0.022
CG9894	CG9894 gene product from transcript CG9894-RB	0.022
mthl4	methuselah-like 4	0.022	Fly
Glut1	Glucose transporter 1	0.021
cher	cheerio	0.021
Rab30	CG9100 gene product from transcript CG9100-RB	0.021
Or59a	Odorant receptor 59a	0.021
Ilp2	Insulin-like peptide 2	0.021
CG3563	CG3563 gene product from transcript CG3563-RA	0.021
inaE	inactivation no afterpotential E	0.021
CG10638	CG10638 gene product from transcript CG10638-RA	0.021	Human
LpR2	CG31092 gene product from transcript CG31092-RD	0.020
up	upheld	0.020
HDAC6	CG6170 gene product from transcript CG6170-RA	0.020	Human
CG17029	CG17029 gene product from transcript CG17029-RA	0.020
t	tan	0.020
CG8446	CG8446 gene product from transcript CG8446-RC	0.020
alpha-Spec	alpha Spectrin	0.020
hk	hook	0.020
CadN	Cadherin-N	0.020
haf	hattifattener	0.019
CG11913	CG11913 gene product from transcript CG11913-RB	0.019
CG1806	CG1806 gene product from transcript CG1806-RA	0.019
Dredd	Death related ced-3/Nedd2-like protein	0.019
Men	Malic enzyme	0.019
G-ialpha65A	G protein alphai subunit 65A	0.019
Pglym78	Phosphoglyceromutase	0.019
CG7181	CG7181 gene product from transcript CG7181-RA	0.019
disco	disconnected	0.019
CG5009	CG5009 gene product from transcript CG5009-RA	0.019
stnB	stoned B	0.019
CG3011	CG3011 gene product from transcript CG3011-RA	0.019
shg	shotgun	0.019
CG18480	CG18480 gene product from transcript CG18480-RA	0.019
ptc	patched	0.018
CanA-14F	Calcineurin A at 14F	0.018
fusl	fuseless	0.018
rap	retina aberrant in pattern	0.018
klg	klingon	0.018
Rho1	CG8416 gene product from transcript CG8416-RB	0.018
CG7918	CG7918 gene product from transcript CG7918-RA	0.018
E(Pc)	Enhancer of Polycomb	0.018
Dsk	Drosulfakinin	0.017
CG15529	CG15529 gene product from transcript CG15529-RA	0.017
CG33138	CG33138 gene product from transcript CG33138-RA	0.017
wdb	widerborst	0.017
CG5355	CG5355 gene product from transcript CG5355-RA	0.017
Caps	Calcium activated protein for secretion	0.017
knrl	knirps-like	0.017
bab1	bric a brac 1	0.017
Ephrin	CG1862 gene product from transcript CG1862-RA	0.017
CG5282	CG5282 gene product from transcript CG5282-RA	0.017
CG15461	CG15461 gene product from transcript CG15461-RA	0.017
Cwc25	CG2843 gene product from transcript CG2843-RA	0.017
Mt2	Methyltransferase 2	0.016
sni	sniffer	0.016
mthl3	methuselah-like 3	0.016	Fly
NijA	Ninjurin A	0.016
CG9232	CG9232 gene product from transcript CG9232-RA	0.016
e	ebony	0.016
robl62A	CG1014 gene product from transcript CG1014-RA	0.016
CG4021	CG4021 gene product from transcript CG4021-RA	0.016
ru	roughoid	0.016
Nrx-1	Neurexin 1	0.016
WRNexo	WRN exonuclease	0.015
CG18662	CG18662 gene product from transcript CG18662-RA	0.015
CG31156	CG31156 gene product from transcript CG31156-RA	0.015
emp	epithelial membrane protein	0.015
Cyp18a1	Cytochrome P450-18a1	0.015
Mekk1	CG7717 gene product from transcript CG7717-RB	0.015
fh	frataxin homolog	0.015
repo	reversed polarity	0.015
CG3683	CG3683 gene product from transcript CG3683-RC	0.015
mus209	mutagen-sensitive 209	0.015
CG2862	CG2862 gene product from transcript CG2862-RA	0.014
Bsg	Basigin	0.014
CG4880	CG4880 gene product from transcript CG4880-RA	0.014
CG13747	CG13747 gene product from transcript CG13747-RA	0.014
Tsp42Ed	Tetraspanin 42Ed	0.014
Ric	Ras which interacts with Calmodulin	0.014
nxf2	nuclear RNA export factor 2	0.014
sun	stunted	0.014
shi	shibire	0.014
Thd1	CG1981 gene product from transcript CG1981-RA	0.014
PGRP-LE	Peptidoglycan recognition protein LE	0.014
kay	kayak	0.014	Human Rat
Rac2	CG8556 gene product from transcript CG8556-RA	0.014
IP3K1	Inositol 1,4,5-triphosphate kinase 1	0.014
CG8306	CG8306 gene product from transcript CG8306-RA	0.014
ics	icarus	0.014
CycJ	Cyclin J	0.014
ap	apterous	0.014
Myo61F	Myosin 61F	0.014
blow	blown fuse	0.014
ImpL2	Ecdysone-inducible gene L2	0.014
pHCl	CG33989 gene product from transcript CG33989-RD	0.014
RpL22-like	Ribosomal protein L22-like	0.014
Caki	Calcium/calmodulin-dependent protein kinase	0.013
Hsp70Ba	Heat-shock-protein-70Ba	0.013
endoA	endophilin A	0.013
edl	ETS-domain lacking	0.013
pdm3	pou domain motif 3	0.013
dl	dorsal	0.013
CG3321	CG3321 gene product from transcript CG3321-RC	0.013
pain	painless	0.013
AcCoAS	Acetyl Coenzyme A synthase	0.013
Hnf4	Hepatocyte nuclear factor 4	0.013
drk	downstream of receptor kinase	0.013
Sos	Son of sevenless	0.013
dpn	deadpan	0.013
ro	rough	0.013
Ppt1	Palmitoyl-protein thioesterase 1	0.012
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.012
bmm	brummer	0.012
SelR	CG6584 gene product from transcript CG6584-RI	0.012
NELF-B	CG32721 gene product from transcript CG32721-RA	0.012
dimm	dimmed	0.012
Gr61a	Gustatory receptor 61a	0.012
Duox	Dual oxidase	0.012
CG15917	CG15917 gene product from transcript CG15917-RA	0.012
ninaB	neither inactivation nor afterpotential B	0.012
Moe	Moesin	0.012
CG17107	CG17107 gene product from transcript CG17107-RA	0.012
CG9752	CG9752 gene product from transcript CG9752-RA	0.012
CG9090	CG9090 gene product from transcript CG9090-RA	0.012
p53	CG33336 gene product from transcript CG33336-RB	0.012
wupA	wings up A	0.012
Atg7	Autophagy-specific gene 7	0.012
dnc	dunce	0.012
CG13604	CG13604 gene product from transcript CG13604-RD	0.012
Hsp67Bc	Heat shock gene 67Bc	0.011
comm2	CG7554 gene product from transcript CG7554-RA	0.011
CG12171	CG12171 gene product from transcript CG12171-RA	0.011
Gr64b	Gustatory receptor 64b	0.011
asf1	anti-silencing factor 1	0.011
nec	necrotic	0.011
neuroligin	CG13772 gene product from transcript CG13772-RA	0.011
CG32635	CG32635 gene product from transcript CG32635-RA	0.011
Pepck	Phosphoenolpyruvate carboxykinase	0.011
hiw	highwire	0.011
CG8907	CG8907 gene product from transcript CG8907-RA	0.011
Gr43a	Gustatory receptor 43a	0.011
Pld	Phospholipase D	0.011	Rat
CG3632	CG3632 gene product from transcript CG3632-RH	0.011
IFa	IFamide	0.011
Shaw	Shaker cognate w	0.011
CG14683	CG14683 gene product from transcript CG14683-RA	0.011
Gr64c	Gustatory receptor 64c	0.011
skpF	CG12227 gene product from transcript CG12227-RA	0.011
vib	vibrator	0.011
pdfr	PDF receptor	0.011
CG18624	CG18624 gene product from transcript CG18624-RC	0.011
Pvf3	PDGF- and VEGF-related factor 3	0.011
hts	hu li tai shao	0.011
CG5399	CG5399 gene product from transcript CG5399-RA	0.011
Mp20	Muscle protein 20	0.011
Rim	CG33547 gene product from transcript CG33547-RB	0.011
CG10713	CG10713 gene product from transcript CG10713-RA	0.011
CG17109	CG17109 gene product from transcript CG17109-RA	0.011
CG16742	CG16742 gene product from transcript CG16742-RA	0.011
dys	dysfusion	0.011
CG3192	CG3192 gene product from transcript CG3192-RA	0.011
Taf7	TBP-associated factor 7	0.011
CG10803	CG10803 gene product from transcript CG10803-RA	0.010
Cyp303a1	CG4163 gene product from transcript CG4163-RA	0.010
CG9083	CG9083 gene product from transcript CG9083-RB	0.010
CG10103	CG10103 gene product from transcript CG10103-RA	0.010
hb	hunchback	0.010
CG15831	CG15831 gene product from transcript CG15831-RB	0.010
Rab23	CG2108 gene product from transcript CG2108-RA	0.010
Hml	Hemolectin	0.010
CG9784	CG9784 gene product from transcript CG9784-RA	0.010
TpnC41C	Troponin C at 41C	0.010
CG4324	CG4324 gene product from transcript CG4324-RA	0.010
S6kII	RPS6-protein kinase-II	0.010
Tre	Trehalose-sensitivity	0.010
CG1927	CG1927 gene product from transcript CG1927-RA	0.010
Cp1	Cysteine proteinase-1	0.010
gcl	germ cell-less	0.010
CG34012	CG34012 gene product from transcript CG34012-RA	0.010
Mst87F	Male-specific RNA 87F	0.010
Tim13	CG11611 gene product from transcript CG11611-RA	0.010
CG8709	CG8709 gene product from transcript CG8709-RK	0.010
CG11376	CG11376 gene product from transcript CG11376-RA	0.010