IMP: Integrative Multi-species Prediction

Drosophila melanogaster

27 genes annotated in fly

Multi-species View

actin filament polymerization

GO:0030041

Assembly of actin filaments by the addition of actin monomers to a filament.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "actin filament polymerization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "actin filament polymerization" (in gray)

Name	Description	Probability	Func Analog Organism
chic	chickadee	0.983
p120ctn	Adherens junction protein p120	0.873
mbc	myoblast city	0.812
Arp66B	Actin-related protein 66B	0.785	Human Yeast Worm
Vrp1	Verprolin 1	0.734
ena	enabled	0.695	Mouse
Rac1	CG2248 gene product from transcript CG2248-RA	0.670	Mouse Fly
katanin-60	katanin 60	0.648
Hem	HEM-protein	0.620	Mouse
bif	bifocal	0.611
Abi	Abelson interacting protein	0.571
cta	concertina	0.564
cpb	capping protein beta	0.562
WASp	CG1520 gene product from transcript CG1520-RA	0.527
Rho1	CG8416 gene product from transcript CG8416-RB	0.492
par-1	CG8201 gene product from transcript CG8201-RA	0.447
spas	spastin	0.439
Arc-p34	CG10954 gene product from transcript CG10954-RA	0.406	Human
gig	gigas	0.385
Cortactin	CG3637 gene product from transcript CG3637-RA	0.375
cpa	capping protein alpha	0.351
Pak	PAK-kinase	0.348	Human
robo	roundabout	0.329
Rala	Ras-related protein	0.317
Rab11	Rab-protein 11	0.313
twf	twinfilin	0.301
baz	bazooka	0.295
rok	Rho-kinase	0.288	Fly
trc	tricornered	0.268
CkIIbeta	Casein kinase II beta subunit	0.266
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.241
plexA	plexin A	0.225
Cdc42	CG12530 gene product from transcript CG12530-RA	0.216
trio	CG18214 gene product from transcript CG18214-RA	0.207	Worm
X11L	CG5675 gene product from transcript CG5675-RB	0.206
msn	misshapen	0.205
cindr	CIN85 and CD2AP orthologue	0.196
Sop2	Suppressor of profilin 2	0.190	Human Yeast
Sos	Son of sevenless	0.189
par-6	CG5884 gene product from transcript CG5884-RA	0.179
sls	sallimus	0.177
Arp14D	Actin-related protein 14D	0.167	Human Yeast Worm
Mtl	Mig-2-like	0.164	Fly
Akt1	CG4006 gene product from transcript CG4006-RA	0.159
Btk29A	Btk family kinase at 29A	0.158
usp	ultraspiracle	0.154
sqh	spaghetti squash	0.151
Sra-1	specifically Rac1-associated protein 1	0.150
Pkn	Protein kinase related to protein kinase N	0.150
BicD	Bicaudal D	0.149
Dcr-2	Dicer-2	0.132
Arf51F	ADP ribosylation factor 51F	0.132	Human
CG8578	CG8578 gene product from transcript CG8578-RA	0.130
G-oalpha47A	G protein oalpha 47A	0.129
spir	spire	0.128
Mical	Molecule interacting with CasL	0.115
flr	flare	0.115
cora	coracle	0.106
rap	retina aberrant in pattern	0.100
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.098
Pten	CG5671 gene product from transcript CG5671-RB	0.096
wdb	widerborst	0.095
Lasp	CG3849 gene product from transcript CG3849-RB	0.094
RhoGEF2	CG9635 gene product from transcript CG9635-RF	0.092
rst	roughest	0.090	Mouse
lqfR	liquid facets-Related	0.089
Eph	Eph receptor tyrosine kinase	0.087
S6k	RPS6-p70-protein kinase	0.085
Ptp69D	Protein tyrosine phosphatase 69D	0.085
RhoGAPp190	CG32555 gene product from transcript CG32555-RB	0.084
drpr	draper	0.082
stai	stathmin	0.082
kuz	kuzbanian	0.082
shot	short stop	0.081
Ephrin	CG1862 gene product from transcript CG1862-RA	0.080
Chc	Clathrin heavy chain	0.080
drk	downstream of receptor kinase	0.080	Yeast Mouse
otk	off-track	0.077
alpha-Spec	alpha Spectrin	0.075
ttk	tramtrack	0.072
egl	egalitarian	0.070
CG11299	CG11299 gene product from transcript CG11299-RA	0.070
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.069
zip	zipper	0.069
rin	rasputin	0.066
didum	dilute class unconventional myosin	0.064
cnc	cap-n-collar	0.064
Mrtf	Myocardin-related transcription factor	0.063
Fak56D	Focal Adhesion Kinase	0.062	Human
Shc	SHC-adaptor protein	0.061
DAAM	Dishevelled Associated Activator of Morphogenesis	0.061
capu	cappuccino	0.060
vav	CG7893 gene product from transcript CG7893-RB	0.060
egh	egghead	0.059
Tak1	TGF-beta activated kinase 1	0.059
fra	frazzled	0.058
Dad	Daughters against dpp	0.058
srp	serpent	0.055
futsch	CG34387 gene product from transcript CG34387-RC	0.055
shrb	shrub	0.055
pum	pumilio	0.054
Atpalpha	Na pump alpha subunit	0.054
CG32556	CG32556 gene product from transcript CG32556-RB	0.053
Mlc2	Myosin light chain 2	0.052
hts	hu li tai shao	0.052	Human
Mob2	CG11711 gene product from transcript CG11711-RC	0.051
aop	anterior open	0.051
da	daughterless	0.051
hep	hemipterous	0.049
Cip4	CG15015 gene product from transcript CG15015-RA	0.049
lace	CG4162 gene product from transcript CG4162-RA	0.049
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.048
CG10641	CG10641 gene product from transcript CG10641-RA	0.048
sn	singed	0.048
Rac2	CG8556 gene product from transcript CG8556-RA	0.048	Mouse Fly
HSPC300	CG30173 gene product from transcript CG30173-RA	0.046
kirre	kin of irre	0.044
Pak3	CG14895 gene product from transcript CG14895-RA	0.043
exba	extra bases	0.043
alpha-Cat	alpha Catenin	0.043
dap	dacapo	0.042
sec5	CG8843 gene product from transcript CG8843-RA	0.042
tomosyn	CG17762 gene product from transcript CG17762-RB	0.042
Pk61C	Protein kinase 61C	0.041
Prm	Paramyosin	0.040
rols	rolling pebbles	0.039
alpha-Adaptin	CG4260 gene product from transcript CG4260-RA	0.039
Apc	APC-like	0.038
Tom34	Translocase of outer membrane 34	0.038
Rab7	Rab-protein 7	0.038
Caps	Calcium activated protein for secretion	0.038
Rab6	Rab-protein 6	0.038
RhoGAP92B	CG4755 gene product from transcript CG4755-RA	0.037
Act5C	Actin 5C	0.036
flw	flapwing	0.036
dsh	dishevelled	0.035
CG1021	CG1021 gene product from transcript CG1021-RE	0.035
HmgD	High mobility group protein D	0.035
Gga	CG3002 gene product from transcript CG3002-RB	0.034
numb	CG3779 gene product from transcript CG3779-RB	0.034
Peb	Protein ejaculatory bulb	0.033
spen	split ends	0.033
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.033
blow	blown fuse	0.033
step	steppke	0.033
Actn	alpha actinin	0.033
Jra	Jun-related antigen	0.033
CkIalpha	Casein kinase Ialpha	0.032
luna	CG33473 gene product from transcript CG33473-RB	0.032
puc	puckered	0.032
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.032
Mlc-c	Myosin light chain cytoplasmic	0.032
kel	kelch	0.032
Syx1A	Syntaxin 1A	0.031
mbf1	multiprotein bridging factor 1	0.031
CG7158	CG7158 gene product from transcript CG7158-RA	0.031
bsk	basket	0.031
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.030
ttv	tout-velu	0.030
Wnt5	Wnt oncogene analog 5	0.030
stc	shuttle craft	0.030
l(2)gl	lethal (2) giant larvae	0.030
sec6	CG5341 gene product from transcript CG5341-RA	0.030
fwd	four wheel drive	0.029
Pabp2	CG2163 gene product from transcript CG2163-RA	0.029
Dlic	Dynein light intermediate chain	0.029
Arc-p20	CG5972 gene product from transcript CG5972-RA	0.029
Zasp66	Z band alternatively spliced PDZ-motif protein 66	0.028
lea	leak	0.028
plexB	plexin B	0.028
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.028
Rab5	Rab-protein 5	0.028
scb	scab	0.028
p16-ARC	CG9881 gene product from transcript CG9881-RA	0.026
robo3	CG5423 gene product from transcript CG5423-RA	0.026
tay	tay bridge	0.026
Marf	Mitochondrial assembly regulatory factor	0.026
Tm2	Tropomyosin 2	0.025	Rat Worm
rl	rolled	0.025
CG10083	CG10083 gene product from transcript CG10083-RA	0.025
Adf1	Adh transcription factor 1	0.025
G-ialpha65A	G protein alphai subunit 65A	0.025
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.025
in	inturned	0.025
Ppt1	Palmitoyl-protein thioesterase 1	0.024
Kap-alpha3	karyopherin alpha3	0.024
Sh3beta	CG8582 gene product from transcript CG8582-RD	0.024
lig	lingerer	0.024
Atg1	Autophagy-specific gene 1	0.024
dock	dreadlocks	0.024	Human Mouse
Pi3K21B	CG2699 gene product from transcript CG2699-RA	0.024
pigs	pickled eggs	0.023
Appl	beta amyloid protein precursor-like	0.023
myoglianin	CG1838 gene product from transcript CG1838-RD	0.023
how	held out wings	0.023
tai	taiman	0.023
Snx6	CG8282 gene product from transcript CG8282-RA	0.023
frtz	fritz	0.023
CG12112	CG12112 gene product from transcript CG12112-RA	0.022
mav	maverick	0.022
Lis-1	Lissencephaly-1	0.022
mys	myospheroid	0.022
Act88F	Actin 88F	0.022
Ced-12	CG5336 gene product from transcript CG5336-RA	0.022
pyd	polychaetoid	0.022
CG5447	CG5447 gene product from transcript CG5447-RA	0.022
Ten-m	Tenascin major	0.021
Mat1	CG7614 gene product from transcript CG7614-RA	0.021
mus308	mutagen-sensitive 308	0.021
wts	warts	0.021	Human
CG5168	CG5168 gene product from transcript CG5168-RB	0.021
cdi	center divider	0.021
Nmnat	Nicotinamide mononucleotide adenylyltransferase	0.021
enc	encore	0.020
rut	rutabaga	0.020
pod1	CG4532 gene product from transcript CG4532-RF	0.020	Human
mib2	mind bomb 2	0.020
synj	synaptojanin	0.020
PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	0.020
dgo	diego	0.020
jim	CG11352 gene product from transcript CG11352-RB	0.020
CG10098	CG10098 gene product from transcript CG10098-RA	0.020
dos	daughter of sevenless	0.020
Pen	Pendulin	0.020
CrebB-17A	Cyclic-AMP response element binding protein B at 17A	0.020
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.019
p130CAS	CG1212 gene product from transcript CG1212-RA	0.019
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.019
MED26	Mediator complex subunit 26	0.019
CG17082	CG17082 gene product from transcript CG17082-RD	0.019
Hrb87F	Heterogeneous nuclear ribonucleoprotein at 87F	0.019
LIMK1	LIM-kinase1	0.019
not	non-stop	0.019
Exp6	Exportin 6	0.018
Cad99C	CG31009 gene product from transcript CG31009-RB	0.018
mwh	multiple wing hairs	0.018
spz	spatzle	0.018
Tao-1	CG14217 gene product from transcript CG14217-RF	0.018
Syb	Synaptobrevin	0.018
CG6051	CG6051 gene product from transcript CG6051-RB	0.018
CG3563	CG3563 gene product from transcript CG3563-RA	0.018
eve	even skipped	0.018
Abl	Abl tyrosine kinase	0.018	Rat
Stim	Stromal interaction molecule	0.018
c11.1	CG12132 gene product from transcript CG12132-RA	0.018
chico	CG5686 gene product from transcript CG5686-RB	0.018
ck	crinkled	0.018
RASSF8	CG5053 gene product from transcript CG5053-RA	0.018
Zn72D	CG5215 gene product from transcript CG5215-RB	0.018
babo	baboon	0.017
Src64B	Src oncogene at 64B	0.017	Fly
Act57B	Actin 57B	0.017
sav	salvador	0.017
jar	jaguar	0.017
mfrn	mitoferrin	0.017
foxo	forkhead box, sub-group O	0.017
CG8765	CG8765 gene product from transcript CG8765-RA	0.017
bchs	blue cheese	0.017
mts	microtubule star	0.017
pcx	pecanex	0.017
neur	neuralized	0.017
SdhA	Succinate dehydrogenase A	0.017
Uba1	Ubiquitin activating enzyme 1	0.017
Mlp84B	Muscle LIM protein at 84B	0.017
ik2	IkappaB kinase-like 2	0.017
sano	serrano	0.017
bora	aurora borealis	0.016
CG31224	CG31224 gene product from transcript CG31224-RA	0.016
comm	commissureless	0.016
S6kII	RPS6-protein kinase-II	0.016
Nrg	Neuroglian	0.016
bip2	CG2009 gene product from transcript CG2009-RA	0.016
sws	swiss cheese	0.016
Hip14	Huntingtin-interacting protein 14	0.016
Fhos	CG42610 gene product from transcript CG42610-RC	0.016
coro	CG9446 gene product from transcript CG9446-RC	0.016	Mouse
Dmn	Dynamitin	0.016
CG2219	CG2219 gene product from transcript CG2219-RA	0.016
unc-104	CG8566 gene product from transcript CG8566-RB	0.015
CG4030	CG4030 gene product from transcript CG4030-RA	0.015
Alk	CG8250 gene product from transcript CG8250-RA	0.015
CG12470	CG12470 gene product from transcript CG12470-RA	0.015
CG15602	CG15602 gene product from transcript CG15602-RA	0.015
fog	folded gastrulation	0.015
Rab23	CG2108 gene product from transcript CG2108-RA	0.015
Vhl	von Hippel-Lindau	0.015
Snap24	Synapse protein 24	0.015
endoA	endophilin A	0.015
insc	inscuteable	0.015
Cg25C	Collagen type IV	0.015
zfh1	Zn finger homeodomain 1	0.015
CG32528	CG32528 gene product from transcript CG32528-RA	0.015
ben	bendless	0.015
Rbcn-3B	Rabconnectin-3B	0.015
wun	wunen	0.015
CG33095	CG33095 gene product from transcript CG33095-RB	0.014
SH3PX1	CG6757 gene product from transcript CG6757-RA	0.014
Nrx-IV	Neurexin IV	0.014
lmd	lame duck	0.014
Hph	HIF prolyl hydroxylase	0.014
trr	trithorax-related	0.014
CG11486	CG11486 gene product from transcript CG11486-RG	0.014
Ube3a	Ubiquitin protein ligase E3A	0.014
CG11811	CG11811 gene product from transcript CG11811-RA	0.014
Lim3	CG10699 gene product from transcript CG10699-RB	0.014
Stam	Signal transducing adaptor molecule	0.014
MED14	Mediator complex subunit 14	0.014
CHKov1	CG10618 gene product from transcript CG10618-RB	0.014
raw	CG12437 gene product from transcript CG12437-RB	0.014
Eps-15	Epidermal growth factor receptor pathway substrate clone 15	0.014
fas	faint sausage	0.014
milt	milton	0.014
CG1468	CG1468 gene product from transcript CG1468-RA	0.014
SoxN	SoxNeuro	0.014
faf	fat facets	0.013
pfk	piefke	0.013
garz	gartenzwerg	0.013
tutl	turtle	0.013
mus301	mutagen-sensitive 301	0.013
Coq2	Coenzyme Q biosynthesis protein 2	0.013
htl	heartless	0.013
Pvr	PDGF- and VEGF-receptor related	0.013
spdo	sanpodo	0.013
CG3371	CG3371 gene product from transcript CG3371-RA	0.013
hbs	hibris	0.013	Mouse
Pde8	Phosphodiesterase 8	0.013
Mp20	Muscle protein 20	0.013
CG3893	CG3893 gene product from transcript CG3893-RA	0.013
CG31687	CG31687 gene product from transcript CG31687-RA	0.013
ref(2)P	refractory to sigma P	0.013
Hip1	Huntingtin interacting protein 1	0.013
cbt	cabut	0.013
Past1	Putative Achaete Scute Target 1	0.013
Karybeta3	Karyopherin beta 3	0.012
Eip63E	Ecdysone-induced protein 63E	0.012
Tig	Tiggrin	0.012
yata	CG1973 gene product from transcript CG1973-RA	0.012
kermit	CG11546 gene product from transcript CG11546-RB	0.012
CG11791	CG11791 gene product from transcript CG11791-RB	0.012
mmy	mummy	0.012
Unc-76	CG3981 gene product from transcript CG3981-RB	0.012
qm	quemao	0.012
shark	Src homology 2, ankyrin repeat, tyrosine kinase	0.012
CG3573	CG3573 gene product from transcript CG3573-RA	0.012
mbt	mushroom bodies tiny	0.012
Npc1a	Niemann-Pick type C-1a	0.012
Acsl	Acyl-CoA synthetase long-chain	0.012
tipE	temperature-induced paralytic E	0.012
Vinc	Vinculin	0.012
sina	seven in absentia	0.012
Patj	CG12021 gene product from transcript CG12021-RC	0.012
repo	reversed polarity	0.012
Klc	Kinesin light chain	0.012
btl	breathless	0.012
betaInt-nu	beta[nu] integrin	0.012
Sox14	Sox box protein 14	0.012
Mhc	Myosin heavy chain	0.012
cib	ciboulot	0.012
CG32813	CG32813 gene product from transcript CG32813-RE	0.011
CG11426	CG11426 gene product from transcript CG11426-RA	0.011
Ras64B	Ras oncogene at 64B	0.011
CG10260	CG10260 gene product from transcript CG10260-RB	0.011
Ac76E	Adenylyl cyclase 76E	0.011
CG17019	CG17019 gene product from transcript CG17019-RA	0.011
Nrx-1	Neurexin 1	0.011
CanB2	Calcineurin B2	0.011
sns	sticks and stones	0.011	Mouse
CG10413	CG10413 gene product from transcript CG10413-RA	0.011
CG3638	CG3638 gene product from transcript CG3638-RE	0.011
CG9866	CG9866 gene product from transcript CG9866-RA	0.011
RhoGDI	CG7823 gene product from transcript CG7823-RA	0.011
sqd	squid	0.011
CalpB	Calpain-B	0.011
l(2)k16918	lethal (2) k16918	0.011
Rassf	Ras association family member	0.011
Su(z)2	Suppressor of zeste 2	0.011
TwdlN	TweedleN	0.011
CG3967	CG3967 gene product from transcript CG3967-RC	0.011
mid	midline	0.011
Tsp86D	Tetraspanin 86D	0.011
hkb	huckebein	0.011
zpg	zero population growth	0.011
Mkp3	Mitogen-activated protein kinase phosphatase 3	0.011
l(1)G0232	lethal (1) G0232	0.011
CadN	Cadherin-N	0.011
tup	tailup	0.011
wupA	wings up A	0.011
CG5869	CG5869 gene product from transcript CG5869-RA	0.011
tamo	CG4057 gene product from transcript CG4057-RA	0.011
Dap160	Dynamin associated protein 160	0.011
wdp	windpipe	0.011
Miro	Mitochondrial Rho	0.010
Rep	Rab escort protein	0.010
kon	kon-tiki	0.010
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.010
ImpL3	Ecdysone-inducible gene L3	0.010
TBPH	CG10327 gene product from transcript CG10327-RC	0.010
Ubp64E	Ubiquitin-specific protease 64E	0.010
CG5385	CG5385 gene product from transcript CG5385-RA	0.010
Gem3	Gemin3	0.010
Myd88	CG2078 gene product from transcript CG2078-RA	0.010
RanBPM	Ran-binding protein M	0.010
Scgdelta	Sarcoglycan delta	0.010
Tango10	Transport and Golgi organization	0.010
squ	squash	0.010
Apc2	Adenomatous polyposis coli tumor suppressor homolog 2	0.010
grk	gurken	0.010
CG1572	CG1572 gene product from transcript CG1572-RA	0.010
Dscam	Down syndrome cell adhesion molecule	0.010
GstS1	Glutathione S transferase S1	0.010