IMP: Integrative Multi-species Prediction

Drosophila melanogaster

31 genes annotated in fly

Multi-species View

negative regulation of protein processing

GO:0010955

Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein processing"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of protein processing" (in gray)

Name	Description	Probability	Func Analog Organism
CSN5	COP9 complex homolog subunit 5	0.112
Su(var)205	Suppressor of variegation 205	0.110
Akt1	CG4006 gene product from transcript CG4006-RA	0.099	Human Mouse Rat
Zyx102EF	CG32018 gene product from transcript CG32018-RA	0.085
dsh	dishevelled	0.083
Vha100-1	CG1709 gene product from transcript CG1709-RF	0.060
pr-set7	CG3307 gene product from transcript CG3307-RC	0.055
th	thread	0.055
B52	CG10851 gene product from transcript CG10851-RB	0.049
pum	pumilio	0.048
Tak1	TGF-beta activated kinase 1	0.048
frtz	fritz	0.039
rpr	reaper	0.038
fzy	fizzy	0.038	Yeast
bam	bag of marbles	0.037
rin	rasputin	0.036
CycE	Cyclin E	0.036
CG10722	CG10722 gene product from transcript CG10722-RA	0.035
Cam	Calmodulin	0.034
CycA	Cyclin A	0.033
Hsp27	Heat shock protein 27	0.033
dap	dacapo	0.032
fon	fondue	0.032
dl	dorsal	0.031
Sp7	Serine protease 7	0.030
lgs	legless	0.030
wg	wingless	0.030	Mouse
SAK	Sak kinase	0.027
brat	brain tumor	0.027
fwd	four wheel drive	0.026
tsr	twinstar	0.026
Abl	Abl tyrosine kinase	0.026
Socs36E	Suppressor of cytokine signaling at 36E	0.025
Cdc37	CG12019 gene product from transcript CG12019-RA	0.025
CG6361	CG6361 gene product from transcript CG6361-RA	0.023
flfl	falafel	0.023
grass	Gram-positive Specific Serine protease	0.023
N	Notch	0.023
skpA	CG16983 gene product from transcript CG16983-RD	0.022
spag	spaghetti	0.022
Xe7	CG2179 gene product from transcript CG2179-RA	0.022
jing	CG9397 gene product from transcript CG9397-RI	0.022
Map60	Microtubule-associated protein 60	0.022
asl	asterless	0.022
Egfr	Epidermal growth factor receptor	0.021
MP1	Melanization Protease 1	0.021
Nrg	Neuroglian	0.021
zip	zipper	0.020
Bap55	Brahma associated protein 55kD	0.020
lds	lodestar	0.020
ncd	non-claret disjunctional	0.020
CG10032	CG10032 gene product from transcript CG10032-RA	0.020
Gef26	CG9491 gene product from transcript CG9491-RB	0.020
Imp	IGF-II mRNA-binding protein	0.019
fz2	frizzled 2	0.019
spn-D	spindle D	0.019
Ras85D	Ras oncogene at 85D	0.019
Vps36	Vacuolar protein sorting 36	0.019
bnl	branchless	0.019
Tbp-1	Tat-binding protein-1	0.019
fax	failed axon connections	0.018
Psa	Puromycin sensitive aminopeptidase	0.018
cdc16	CG6759 gene product from transcript CG6759-RA	0.017
Src64B	Src oncogene at 64B	0.017	Human
Sir2	CG5216 gene product from transcript CG5216-RA	0.017
kl-5	male fertility factor kl5	0.017
unc-13	CG2999 gene product from transcript CG2999-RA	0.017
mi	minus	0.017
Dref	DNA replication-related element factor	0.017
cdc2	CG5363 gene product from transcript CG5363-RA	0.017
CycB	Cyclin B	0.017
Rab11	Rab-protein 11	0.017
Top1	Topoisomerase 1	0.016
CycH	Cyclin H	0.016
toc	toucan	0.016
rap	retina aberrant in pattern	0.016
CG13321	CG13321 gene product from transcript CG13321-RA	0.016
bsk	basket	0.016
CG9772	CG9772 gene product from transcript CG9772-RB	0.016
CG42813	CG42813 gene product from transcript CG42813-RA	0.016
CycT	Cyclin T	0.016
rumi	CG31152 gene product from transcript CG31152-RA	0.016
rtGEF	rho-type guanine exchange factor	0.016
Dcp2	Decapping protein 2	0.015
CycB3	Cyclin B3	0.015
Cul-5	Cullin-5	0.015
p53	CG33336 gene product from transcript CG33336-RB	0.015	Mouse
Trn	Transportin	0.015
Ptp61F	Protein tyrosine phosphatase 61F	0.015
Pp1-87B	Protein phosphatase 1 at 87B	0.015	Yeast
Spn5	Serine protease inhibitor 5	0.014
cdc14	CG7134 gene product from transcript CG7134-RB	0.014
msopa	male-specific opa containing gene	0.014
Su(H)	Suppressor of Hairless	0.014
Mer	Merlin	0.014
Atg8a	Autophagy-specific gene 8a	0.014
sina	seven in absentia	0.014
CG7414	CG7414 gene product from transcript CG7414-RC	0.014
tll	tailless	0.014
orb	oo18 RNA-binding protein	0.014
Xrp1	CG17836 gene product from transcript CG17836-RB	0.014
Past1	Putative Achaete Scute Target 1	0.014
Smg1	CG32743 gene product from transcript CG32743-RA	0.014
qkr58E-1	quaking related 58E-1	0.014
colt	congested-like trachea	0.014
debcl	death executioner Bcl-2 homologue	0.014
tai	taiman	0.014
Uba2	Smt3 activating enzyme 2	0.014
RanBP3	Ran binding protein 3	0.014
hep	hemipterous	0.014
ago	archipelago	0.014
wnd	wallenda	0.014
Pkc98E	Protein C kinase 98E	0.014
Tip60	CG6121 gene product from transcript CG6121-RA	0.013
CG32264	CG32264 gene product from transcript CG32264-RH	0.013
flr	flare	0.013
rok	Rho-kinase	0.013
Upf1	CG1559 gene product from transcript CG1559-RA	0.013
pnt	pointed	0.013
CG7766	CG7766 gene product from transcript CG7766-RC	0.013
yuri	yuri gagarin	0.013
Act42A	Actin 42A	0.013
Grip	Glutamate receptor binding protein	0.013
CG13840	CG13840 gene product from transcript CG13840-RB	0.013
Iswi	Imitation SWI	0.013
Psf2	CG18013 gene product from transcript CG18013-RA	0.013
rl	rolled	0.013
nej	nejire	0.013
par-1	CG8201 gene product from transcript CG8201-RA	0.013
PH4alphaNE3	prolyl-4-hydroxylase-alpha NE3	0.013
Tequila	CG4821 gene product from transcript CG4821-RE	0.013
hh	hedgehog	0.013
cnk	connector enhancer of ksr	0.013
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.013
Cbp80	cap binding protein 80	0.013
PGRP-LC	Peptidoglycan recognition protein LC	0.013
asp	abnormal spindle	0.013
CG16947	CG16947 gene product from transcript CG16947-RA	0.013
CG16721	CG16721 gene product from transcript CG16721-RA	0.013
Cdk7	Cyclin-dependent kinase 7	0.012
Acp70A	Accessory gland peptide 70A	0.012
fs(1)h	female sterile (1) homeotic	0.012
Hsp68	Heat shock protein 68	0.012
hts	hu li tai shao	0.012
GNBP1	Gram-negative bacteria binding protein 1	0.012
Ser	Serrate	0.012
inx2	innexin 2	0.012
endoA	endophilin A	0.012
CG12766	CG12766 gene product from transcript CG12766-RA	0.012
CYLD	cylindromatosis	0.012
sn	singed	0.012
CG6412	CG6412 gene product from transcript CG6412-RA	0.012
CSN4	COP9 complex homolog subunit 4	0.012
dan	distal antenna	0.012
plu	plutonium	0.012
Tom70	Translocase of outer membrane 70	0.012
edl	ETS-domain lacking	0.012
Mst57Dc	Male-specific RNA 57Dc	0.012
vsg	visgun	0.012
Dip3	Dorsal interacting protein 3	0.012
betaTub60D	beta-Tubulin at 60D	0.012
CG6439	CG6439 gene product from transcript CG6439-RA	0.012
CG5835	CG5835 gene product from transcript CG5835-RA	0.012
eyg	eyegone	0.012
CG12162	CG12162 gene product from transcript CG12162-RA	0.012
wech	CG42396 gene product from transcript CG42396-RC	0.012
twin	CG31137 gene product from transcript CG31137-RB	0.012
Spn27A	Serpin 27A	0.012
wapl	wings apart-like	0.012
ena	enabled	0.012
kibra	kibra ortholog	0.012
Ote	Otefin	0.012
drpr	draper	0.012
Rho1	CG8416 gene product from transcript CG8416-RB	0.011
ball	ballchen	0.011
DNApol-alpha60	DNA polymerase alpha 60kD	0.011
Ack	CG14992 gene product from transcript CG14992-RA	0.011
egr	eiger	0.011
CycD	Cyclin D	0.011
neo	neyo	0.011
Snr1	Snf5-related 1	0.011
Arp8	Actin-related protein 8	0.011
CG13965	CG13965 gene product from transcript CG13965-RA	0.011
CG2224	CG2224 gene product from transcript CG2224-RA	0.011
cact	cactus	0.011
Mmp1	Matrix metalloproteinase 1	0.011
bl	bancal	0.011
Rab23	CG2108 gene product from transcript CG2108-RA	0.011	Mouse
bchs	blue cheese	0.011
WRNexo	WRN exonuclease	0.011
CG7033	CG7033 gene product from transcript CG7033-RC	0.011
Fcp1	CG12252 gene product from transcript CG12252-RA	0.011
CG18284	CG18284 gene product from transcript CG18284-RB	0.011
Lasp	CG3849 gene product from transcript CG3849-RB	0.011
cathD	CG1548 gene product from transcript CG1548-RA	0.011
bib	big brain	0.011
Hsp22	Heat shock protein 22	0.011
DJ-1alpha	CG6646 gene product from transcript CG6646-RA	0.011
gish	gilgamesh	0.011
ptc	patched	0.011
lap	like-AP180	0.011	Mouse
CG11037	CG11037 gene product from transcript CG11037-RA	0.011
Arr2	Arrestin 2	0.011	Rat
hiw	highwire	0.011
Parp	Poly-(ADP-ribose) polymerase	0.011
pch2	CG31453 gene product from transcript CG31453-RA	0.011
Hsp67Ba	Heat shock gene 67Ba	0.011	Mouse
CG13089	CG13089 gene product from transcript CG13089-RA	0.011
sty	sprouty	0.011
foxo	forkhead box, sub-group O	0.011
rdgC	retinal degeneration C	0.011
PGRP-LE	Peptidoglycan recognition protein LE	0.011
Drp1	Dynamin related protein 1	0.011
shg	shotgun	0.011
Adf1	Adh transcription factor 1	0.011
CG33293	CG33293 gene product from transcript CG33293-RA	0.010
Ubx	Ultrabithorax	0.010
pigeon	CG10739 gene product from transcript CG10739-RB	0.010
krz	kurtz	0.010	Mouse
kirre	kin of irre	0.010
CG9689	CG9689 gene product from transcript CG9689-RA	0.010
Xbp1	X box binding protein-1	0.010
CG12736	CG12736 gene product from transcript CG12736-RA	0.010
Smg5	CG8954 gene product from transcript CG8954-RA	0.010
jar	jaguar	0.010
XNP	CG4548 gene product from transcript CG4548-RA	0.010
CG3563	CG3563 gene product from transcript CG3563-RA	0.010
CG1572	CG1572 gene product from transcript CG1572-RA	0.010
CG9339	CG9339 gene product from transcript CG9339-RG	0.010
fy	fuzzy	0.010
Rala	Ras-related protein	0.010
CG5346	CG5346 gene product from transcript CG5346-RA	0.010
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.010
CG3415	CG3415 gene product from transcript CG3415-RA	0.010
vps2	CG14542 gene product from transcript CG14542-RA	0.010
cdc2c	CG10498 gene product from transcript CG10498-RC	0.010
MED19	Mediator complex subunit 19	0.010
okr	okra	0.010
Fhos	CG42610 gene product from transcript CG42610-RC	0.010
lute	CG5319 gene product from transcript CG5319-RA	0.010
CG31712	CG31712 gene product from transcript CG31712-RA	0.010
CG13601	CG13601 gene product from transcript CG13601-RA	0.010
CG10527	CG10527 gene product from transcript CG10527-RA	0.010
CG3679	CG3679 gene product from transcript CG3679-RA	0.010
CG10126	CG10126 gene product from transcript CG10126-RB	0.010