IMP: Integrative Multi-species Prediction

Drosophila melanogaster

1 genes annotated in fly

regulation of pathway restricted smad protein phosphorylation

Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of pathway restricted smad protein phosphorylation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of pathway restricted smad protein phosphorylation" (in gray)

Name	Description	Probability	Func Analog Organism
Mad	Mothers against dpp	1.000
sax	saxophone	1.000	Human Fly
tkv	thickveins	1.000	Human Fly
gbb	glass bottom boat	1.000	Human Mouse
Ras85D	Ras oncogene at 85D	0.946
Med	Medea	0.788	Mouse
Egfr	Epidermal growth factor receptor	0.755
ash2	absent, small, or homeotic discs 2	0.645
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.630
Sara	Smad anchor for receptor activation	0.586
dally	division abnormally delayed	0.537
myoglianin	CG1838 gene product from transcript CG1838-RD	0.483
hh	hedgehog	0.394
sd	scalloped	0.345
smo	smoothened	0.326
sog	short gastrulation	0.294
put	punt	0.283	Fly
dco	discs overgrown	0.269
hpo	hippo	0.250
Akt1	CG4006 gene product from transcript CG4006-RA	0.247
Dad	Daughters against dpp	0.245	Human
ci	cubitus interruptus	0.227
EcR	Ecdysone receptor	0.218
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.155
Atg1	Autophagy-specific gene 1	0.143
dm	diminutive	0.135
Tl	Toll	0.125
InR	Insulin-like receptor	0.111
slmb	supernumerary limbs	0.107
rho	rhomboid	0.106
Nrx-1	Neurexin 1	0.103
comt	comatose	0.096
ttv	tout-velu	0.088
rap	retina aberrant in pattern	0.087
dpp	decapentaplegic	0.087	Human
mxc	multi sex combs	0.068
Fak56D	Focal Adhesion Kinase	0.065
mav	maverick	0.065
Plc21C	Phospholipase C at 21C	0.064
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.056
tws	twins	0.056
syd	sunday driver	0.053
Atg6	Autophagy-specific gene 6	0.050
WASp	CG1520 gene product from transcript CG1520-RA	0.048
Rheb	CG1081 gene product from transcript CG1081-RA	0.048
unc-104	CG8566 gene product from transcript CG8566-RB	0.044
daw	dawdle	0.042	Human
lap	like-AP180	0.041
Snap25	Synapse protein 25	0.039
scrib	scribbled	0.037
sll	slalom	0.037
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.037
Pten	CG5671 gene product from transcript CG5671-RB	0.037
shn	schnurri	0.035
Pk61C	Protein kinase 61C	0.035
Irk2	Inwardly rectifying potassium channel 2	0.034
baz	bazooka	0.034
Smg1	CG32743 gene product from transcript CG32743-RA	0.034
dve	defective proventriculus	0.033
Actbeta	Activin-beta	0.033	Human
fbl6	CG13213 gene product from transcript CG13213-RB	0.033
nos	nanos	0.032
Clk	Clock	0.032
Su(H)	Suppressor of Hairless	0.032
Smox	Smad on X	0.032
tll	tailless	0.031
trx	trithorax	0.031
ecd	ecdysoneless	0.030
Stim	Stromal interaction molecule	0.030
Dap160	Dynamin associated protein 160	0.029
Nsf2	NEM-sensitive fusion protein 2	0.029
tld	tolloid	0.029
CG8709	CG8709 gene product from transcript CG8709-RK	0.029
krz	kurtz	0.028
wit	wishful thinking	0.028	Human Fly
coro	CG9446 gene product from transcript CG9446-RC	0.027
Acsl	Acyl-CoA synthetase long-chain	0.027
CG9139	CG9139 gene product from transcript CG9139-RA	0.027
prod	proliferation disrupter	0.027
eya	eyes absent	0.026
kn	knot	0.026
Snoo	Sno oncogene	0.026
beta-Spec	beta Spectrin	0.026
hyd	hyperplastic discs	0.025
Bre1	CG10542 gene product from transcript CG10542-RA	0.025
G-oalpha47A	G protein oalpha 47A	0.024
cg	combgap	0.023
cv-2	crossveinless 2	0.022
por	porcupine	0.022
fng	fringe	0.022
Ubqn	Ubiquilin	0.022
TER94	CG2331 gene product from transcript CG2331-RA	0.022
kek1	kekkon-1	0.022
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.022
hth	homothorax	0.022
Lasp	CG3849 gene product from transcript CG3849-RB	0.022
Pde8	Phosphodiesterase 8	0.021
tim	timeless	0.021
ATPCL	ATP citrate lyase	0.021
Ser	Serrate	0.020
GluRIIA	Glutamate receptor IIA	0.020
Sin3A	CG8815 gene product from transcript CG8815-RC	0.020
sty	sprouty	0.020
cpx	complexin	0.019
kay	kayak	0.019
ex	expanded	0.019
l(2)gl	lethal (2) giant larvae	0.018
GABA-B-R2	metabotropic GABA-B receptor subtype 2	0.018
babo	baboon	0.018
hiw	highwire	0.018
fj	four-jointed	0.018
Gef26	CG9491 gene product from transcript CG9491-RB	0.017
Sac1	CG9128 gene product from transcript CG9128-RB	0.017
Gug	Grunge	0.017
magu	CG2264 gene product from transcript CG2264-RD	0.016
CG3194	CG3194 gene product from transcript CG3194-RB	0.016
wun	wunen	0.016
NFAT	NFAT homolog	0.016
egh	egghead	0.016
Cip4	CG15015 gene product from transcript CG15015-RA	0.015
pex1	peroxin 1	0.015
dsh	dishevelled	0.015
svr	silver	0.015
GluRIIE	Glutamate receptor IIE	0.015
sbb	scribbler	0.015
hig	hikaru genki	0.014
loqs	loquacious	0.014
dia	diaphanous	0.014
tok	tolkin	0.014
cos	costa	0.013
Invadolysin	CG3953 gene product from transcript CG3953-RA	0.013
CG1621	CG1621 gene product from transcript CG1621-RA	0.013
Fer2LCH	Ferritin 2 light chain homologue	0.013
stnA	stoned A	0.013
CG6650	CG6650 gene product from transcript CG6650-RA	0.013
onecut	CG1922 gene product from transcript CG1922-RA	0.013
CG15784	CG15784 gene product from transcript CG15784-RA	0.013
Pp2A-29B	Protein phosphatase 2A at 29B	0.013
Syt4	Synaptotagmin 4	0.012
CG43073	CG43073 gene product from transcript CG43073-RF	0.012
spin	spinster	0.012
zpg	zero population growth	0.012
TfIIS	RNA polymerase II elongation factor	0.012
Aph-4	Alkaline phosphatase 4	0.012
cnk	connector enhancer of ksr	0.012
26-29-p	26-29kD-proteinase	0.012
n-syb	n-synaptobrevin	0.011
Psn	Presenilin	0.011
Upf2	CG2253 gene product from transcript CG2253-RA	0.011
TBPH	CG10327 gene product from transcript CG10327-RC	0.011
drk	downstream of receptor kinase	0.011
Dat	Dopamine N acetyltransferase	0.011
cv	crossveinless	0.011
mys	myospheroid	0.011
byn	brachyenteron	0.011
Uch-L3	Ubiquitin C-terminal hydrolase	0.011
CCS	CG17753 gene product from transcript CG17753-RA	0.011
wg	wingless	0.011
endoA	endophilin A	0.011
ird1	immune response deficient 1	0.011
Adar	Adenosine deaminase acting on RNA	0.011
Dsk	Drosulfakinin	0.011
bgm	bubblegum	0.010