IMP: Integrative Multi-species Prediction

Drosophila melanogaster

31 genes annotated in fly

protein depolymerization

The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein depolymerization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "protein depolymerization" (in gray)

Name	Description	Probability	Func Analog Organism
flr	flare	0.901
exo84	CG6095 gene product from transcript CG6095-RA	0.873
sec8	CG2095 gene product from transcript CG2095-RA	0.818
Det	Deterin	0.675
Klp67A	Kinesin-like protein at 67A	0.564	Human Yeast
bru	brunelleschi	0.560
vib	vibrator	0.554
Dap160	Dynamin associated protein 160	0.491
fwd	four wheel drive	0.355
dia	diaphanous	0.320
Mical	Molecule interacting with CasL	0.313
mtrm	matrimony	0.255
aust	australin	0.230
hts	hu li tai shao	0.225	Human
Arp66B	Actin-related protein 66B	0.207
Lasp	CG3849 gene product from transcript CG3849-RB	0.204
sls	sallimus	0.204
flw	flapwing	0.188
polo	CG12306 gene product from transcript CG12306-RA	0.169
G-oalpha47A	G protein oalpha 47A	0.162
beta-Spec	beta Spectrin	0.150
trc	tricornered	0.140
alpha-Spec	alpha Spectrin	0.131
Marf	Mitochondrial assembly regulatory factor	0.131
Klp3A	Kinesin-like protein at 3A	0.130
asp	abnormal spindle	0.123
Ptp69D	Protein tyrosine phosphatase 69D	0.103
bol	boule	0.097
Spc25	CG7242 gene product from transcript CG7242-RA	0.097
CG11299	CG11299 gene product from transcript CG11299-RA	0.096
Poc1	Proteome of centrioles 1	0.094
rictor	rapamycin-insensitive companion of Tor	0.093
tef	teflon	0.092
bond	james bond	0.089
CG32038	CG32038 gene product from transcript CG32038-RA	0.088
CG10722	CG10722 gene product from transcript CG10722-RA	0.086
mei-38	meiotic 38	0.078
ana2	anastral spindle 2	0.076
DAAM	Dishevelled Associated Activator of Morphogenesis	0.070
wupA	wings up A	0.067
Prm	Paramyosin	0.066
Caps	Calcium activated protein for secretion	0.066
egl	egalitarian	0.065
twf	twinfilin	0.065
CG8443	CG8443 gene product from transcript CG8443-RA	0.065
mats	mob as tumor suppressor	0.061
Mlc2	Myosin light chain 2	0.059
ifc	infertile crescent	0.059
exu	exuperantia	0.058
fry	furry	0.058
ncd	non-claret disjunctional	0.057
Cdc37	CG12019 gene product from transcript CG12019-RA	0.055
up	upheld	0.053
Eps-15	Epidermal growth factor receptor pathway substrate clone 15	0.053
Act5C	Actin 5C	0.053
Trc8	CG2304 gene product from transcript CG2304-RB	0.052
Khc	Kinesin heavy chain	0.052
Bsg	Basigin	0.051
Rae1	CG9862 gene product from transcript CG9862-RA	0.047
Ank2	Ankyrin 2	0.047
sav	salvador	0.046
Grip75	CG6176 gene product from transcript CG6176-RA	0.046
cher	cheerio	0.045
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.044
scra	scraps	0.044
CG3227	CG3227 gene product from transcript CG3227-RA	0.044
mib2	mind bomb 2	0.044
ana3	anastral spindle 3	0.043
chb	chromosome bows	0.043
Lis-1	Lissencephaly-1	0.043
fliI	flightless I	0.042
sas-6	spindle assembly abnormal 6	0.042
eIF4G2	eukaryotic translation initiation factor 4G2	0.040
neb	nebbish	0.040
Klp10A	CG1453 gene product from transcript CG1453-RA	0.040	Human Worm
asl	asterless	0.038
sals	sarcomere length short	0.037
unc-104	CG8566 gene product from transcript CG8566-RB	0.037
Zasp66	Z band alternatively spliced PDZ-motif protein 66	0.037
Sop2	Suppressor of profilin 2	0.037
Pak3	CG14895 gene product from transcript CG14895-RA	0.037
twe	twine	0.037
Ack	CG14992 gene product from transcript CG14992-RA	0.035
mei-P26	CG12218 gene product from transcript CG12218-RA	0.035
Rbsn-5	Rabenosyn-5	0.033
sti	sticky	0.033
mbt	mushroom bodies tiny	0.033
aret	arrest	0.031
nudE	CG8104 gene product from transcript CG8104-RB	0.031
synj	synaptojanin	0.031	Mouse Worm
hiw	highwire	0.031
tomb	tombola	0.031
ssh	slingshot	0.030
klar	klarsicht	0.030
tmod	tropomodulin	0.030	Worm
CG3638	CG3638 gene product from transcript CG3638-RE	0.030
Abl	Abl tyrosine kinase	0.029
Hip14	Huntingtin-interacting protein 14	0.028
Cenp-C	CG31258 gene product from transcript CG31258-RA	0.028
erm	earmuff	0.028
sw	short wing	0.028
lkb1	CG9374 gene product from transcript CG9374-RJ	0.027
Mlc1	Myosin alkali light chain 1	0.027
CG14047	CG14047 gene product from transcript CG14047-RH	0.027
CG4673	CG4673 gene product from transcript CG4673-RB	0.027
CG14215	CG14215 gene product from transcript CG14215-RA	0.026
TER94	CG2331 gene product from transcript CG2331-RA	0.026
WASp	CG1520 gene product from transcript CG1520-RA	0.026
abs	abstrakt	0.025
baz	bazooka	0.025
Ndc80	CG9938 gene product from transcript CG9938-RA	0.025
Cap-G	CG34438 gene product from transcript CG34438-RF	0.024
betaTub85D	beta-Tubulin at 85D	0.024
pbl	pebble	0.023
Rbcn-3B	Rabconnectin-3B	0.023
Ubp64E	Ubiquitin-specific protease 64E	0.023
TSG101	tumor suppressor protein 101	0.023
Msi	Male-specific insect derived growth factor	0.022
vps2	CG14542 gene product from transcript CG14542-RA	0.022
bgcn	benign gonial cell neoplasm	0.022
Grip128	CG9201 gene product from transcript CG9201-RB	0.022
Br140	CG1845 gene product from transcript CG1845-RA	0.022
Drp1	Dynamin related protein 1	0.022
Taz	Tafazzin	0.022
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.022
btz	barentsz	0.022
hyd	hyperplastic discs	0.022
Chc	Clathrin heavy chain	0.022
Ork1	Open rectifier K[+] channel 1	0.021
CG31352	CG31352 gene product from transcript CG31352-RA	0.021
milt	milton	0.021
Tom34	Translocase of outer membrane 34	0.021
robo3	CG5423 gene product from transcript CG5423-RA	0.021
CG4213	CG4213 gene product from transcript CG4213-RA	0.021
Frq1	Frequenin 1	0.020
futsch	CG34387 gene product from transcript CG34387-RC	0.020
Tm2	Tropomyosin 2	0.020	Rat Worm
stj	straightjacket	0.020
Cog7	CG31040 gene product from transcript CG31040-RA	0.020
Pros26	Proteasome 26kD subunit	0.020
gammaTub37C	gamma-Tubulin at 37C	0.020
opa1-like	optic atrophy 1-like	0.020
NAAT1	Nutrient Amino Acid Transporter 1	0.019
Pkn	Protein kinase related to protein kinase N	0.019
borr	borealin-related	0.019
rhea	CG6831 gene product from transcript CG6831-RA	0.019
CG8841	CG8841 gene product from transcript CG8841-RC	0.019
Nmnat	Nicotinamide mononucleotide adenylyltransferase	0.019
Nup54	Nucleoporin 54	0.019
feo	fascetto	0.019
car	carnation	0.019
CG6051	CG6051 gene product from transcript CG6051-RB	0.018
Dhc64C	Dynein heavy chain 64C	0.018
zpg	zero population growth	0.018
CG32392	CG32392 gene product from transcript CG32392-RB	0.018
Dlic	Dynein light intermediate chain	0.018
CG11329	CG11329 gene product from transcript CG11329-RA	0.018
CG2750	CG2750 gene product from transcript CG2750-RB	0.017
Grip71	CG10346 gene product from transcript CG10346-RA	0.017
cmet	CENP-meta	0.017	Yeast
CG32676	CG32676 gene product from transcript CG32676-RA	0.017
Suv4-20	CG13363 gene product from transcript CG13363-RA	0.017
ago	archipelago	0.017
pod1	CG4532 gene product from transcript CG4532-RF	0.017
mav	maverick	0.017
Cg25C	Collagen type IV	0.017
Rbcn-3A	Rabconnectin-3A	0.017
myoglianin	CG1838 gene product from transcript CG1838-RD	0.017
cib	ciboulot	0.017
NiPp1	Nuclear inhibitor of Protein phosphatase 1	0.017
gkt	glaikit	0.017
Act88F	Actin 88F	0.017
Mcm3	Minichromosome maintenance 3	0.016
GluRIIA	Glutamate receptor IIA	0.016
CG8830	CG8830 gene product from transcript CG8830-RB	0.016
rig	rigor mortis	0.016
CG15435	CG15435 gene product from transcript CG15435-RA	0.016
Pink1	PTEN-induced putative kinase 1	0.016
Ts	CG3181 gene product from transcript CG3181-RA	0.016
Mob4	CG3403 gene product from transcript CG3403-RA	0.016
RhoGAP15B	CG4937 gene product from transcript CG4937-RC	0.016
Tm1	Tropomyosin 1	0.016	Rat
mfrn	mitoferrin	0.016
fend	forked end	0.016
CG6954	CG6954 gene product from transcript CG6954-RB	0.016
Act57B	Actin 57B	0.016
LIMK1	LIM-kinase1	0.016
CG13366	CG13366 gene product from transcript CG13366-RA	0.015	Mouse
tum	tumbleweed	0.015
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.015
CG10107	CG10107 gene product from transcript CG10107-RA	0.015
Plap	Phospholipase A2 activator protein	0.015
dbo	diablo	0.015
cue	cueball	0.015
Vrp1	Verprolin 1	0.015
CG5543	CG5543 gene product from transcript CG5543-RA	0.015
Hip1	Huntingtin interacting protein 1	0.015
katanin-60	katanin 60	0.014
mars	CG17064 gene product from transcript CG17064-RB	0.014
CG7202	CG7202 gene product from transcript CG7202-RA	0.014
cdc23	CG2508 gene product from transcript CG2508-RA	0.014
pgant3	polypeptide GalNAc transferase 3	0.014
Past1	Putative Achaete Scute Target 1	0.014
robo	roundabout	0.014
Ppcs	Phosphopantothenoylcysteine synthetase	0.014
CG14442	CG14442 gene product from transcript CG14442-RB	0.014
chinmo	Chronologically inappropriate morphogenesis	0.014
sm	smooth	0.014
btl	breathless	0.014
Sin1	SAPK-interacting protein 1	0.014
nos	nanos	0.014
stv	starvin	0.014
pav	pavarotti	0.014
tacc	transforming acidic coiled-coil protein	0.014
Neurochondrin	CG2330 gene product from transcript CG2330-RA	0.014
CG2224	CG2224 gene product from transcript CG2224-RA	0.014
Amph	Amphiphysin	0.014
form3	formin 3	0.014
CG31146	CG31146 gene product from transcript CG31146-RD	0.014
CG15572	CG15572 gene product from transcript CG15572-RA	0.013
mbf1	multiprotein bridging factor 1	0.013
sec15	CG7034 gene product from transcript CG7034-RA	0.013
CG10512	CG10512 gene product from transcript CG10512-RA	0.013
CG10265	CG10265 gene product from transcript CG10265-RA	0.013
CG7903	CG7903 gene product from transcript CG7903-RA	0.013
MED1	Mediator complex subunit 1	0.013
Grip163	CG5688 gene product from transcript CG5688-RA	0.013
CG4617	CG4617 gene product from transcript CG4617-RA	0.013
CG30178	CG30178 gene product from transcript CG30178-RA	0.013
sima	similar	0.013
Pif1B	PFTAIRE-interacting factor 1B	0.013
CG3530	CG3530 gene product from transcript CG3530-RC	0.013
lat	latheo	0.013
CG11286	CG11286 gene product from transcript CG11286-RA	0.013
CG13838	CG13838 gene product from transcript CG13838-RA	0.013
ena	enabled	0.013
CG3125	CG3125 gene product from transcript CG3125-RA	0.013
CG15365	CG15365 gene product from transcript CG15365-RA	0.013
CG14589	CG14589 gene product from transcript CG14589-RA	0.013
ball	ballchen	0.013
SMC2	CG10212 gene product from transcript CG10212-RA	0.013
CG6486	CG6486 gene product from transcript CG6486-RA	0.013
zen	zerknullt	0.013
CG5381	CG5381 gene product from transcript CG5381-RA	0.013
poe	purity of essence	0.013
CG11120	CG11120 gene product from transcript CG11120-RA	0.013
Mio	Mlx interactor	0.012
CG1737	CG1737 gene product from transcript CG1737-RA	0.012
Kap3	Kinesin associated protein 3	0.012
CG3558	CG3558 gene product from transcript CG3558-RC	0.012
raps	rapsynoid	0.012
Syt4	Synaptotagmin 4	0.012
abo	abnormal oocyte	0.012
Psf1	CG9187 gene product from transcript CG9187-RA	0.012
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.012
vih	vihar	0.012
Rya-r44F	Ryanodine receptor 44F	0.012
Ca-alpha1D	Ca[2+]-channel protein alpha[[1]] subunit D	0.012
pigs	pickled eggs	0.012	Human
Sas-4	CG10061 gene product from transcript CG10061-RA	0.012
CG14759	CG14759 gene product from transcript CG14759-RA	0.012
unc-13	CG2999 gene product from transcript CG2999-RA	0.012
rtGEF	rho-type guanine exchange factor	0.012
CG17098	CG17098 gene product from transcript CG17098-RA	0.012
Cp110	CG14617 gene product from transcript CG14617-RB	0.012
CG1443	CG1443 gene product from transcript CG1443-RA	0.012
Cyp4g1	Cytochrome P450-4g1	0.012
ari-2	ariadne 2	0.012
gish	gilgamesh	0.012
dpa	disc proliferation abnormal	0.012
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.012
fz4	frizzled 4	0.011
Nipped-B	CG17704 gene product from transcript CG17704-RI	0.011
kst	karst	0.011
stl	stall	0.011
par-6	CG5884 gene product from transcript CG5884-RA	0.011
toc	toucan	0.011
lbm	late bloomer	0.011
ens	ensconsin	0.011
CG32081	CG32081 gene product from transcript CG32081-RA	0.011
gukh	GUK-holder	0.011
cora	coracle	0.011
Gef26	CG9491 gene product from transcript CG9491-RB	0.011
O-fut1	O-fucosyltransferase 1	0.011
Bruce	CG6303 gene product from transcript CG6303-RA	0.011
gek	genghis khan	0.011
NK7.1	CG8524 gene product from transcript CG8524-RA	0.011
Pk61C	Protein kinase 61C	0.011
Cad74A	CG6445 gene product from transcript CG6445-RB	0.011
CG6914	CG6914 gene product from transcript CG6914-RA	0.011
tyn	trynity	0.011
Esyt2	CG6643 gene product from transcript CG6643-RA	0.011
CG5491	CG5491 gene product from transcript CG5491-RA	0.011
CG14933	CG14933 gene product from transcript CG14933-RA	0.011
l(3)04053	lethal (3) 04053	0.011
Fak56D	Focal Adhesion Kinase	0.011
bora	aurora borealis	0.011
CG4615	CG4615 gene product from transcript CG4615-RA	0.011
twin	CG31137 gene product from transcript CG31137-RB	0.011
CG1597	CG1597 gene product from transcript CG1597-RB	0.011
Cf2	Chorion factor 2	0.011
ALiX	ALG-2 interacting protein X	0.011
Smr	Smrter	0.011
CG9247	CG9247 gene product from transcript CG9247-RA	0.011
Lerp	lysosomal enzyme receptor protein	0.011
boi	brother of iHog	0.011
CG14006	CG14006 gene product from transcript CG14006-RA	0.011
Klp61F	Kinesin-like protein at 61F	0.011
CG4706	CG4706 gene product from transcript CG4706-RA	0.011
sba	six-banded	0.011
CG12263	CG12263 gene product from transcript CG12263-RA	0.010
Oseg1	CG7161 gene product from transcript CG7161-RA	0.010
CG7852	CG7852 gene product from transcript CG7852-RA	0.010
CG3815	CG3815 gene product from transcript CG3815-RA	0.010
CG2218	CG2218 gene product from transcript CG2218-RA	0.010
CG15147	CG15147 gene product from transcript CG15147-RA	0.010
Invadolysin	CG3953 gene product from transcript CG3953-RA	0.010
CG10510	CG10510 gene product from transcript CG10510-RA	0.010
bam	bag of marbles	0.010
Alas	Aminolevulinate synthase	0.010
CG15764	CG15764 gene product from transcript CG15764-RA	0.010
mi	minus	0.010
CG18316	CG18316 gene product from transcript CG18316-RA	0.010
CG15425	CG15425 gene product from transcript CG15425-RA	0.010
CG13398	CG13398 gene product from transcript CG13398-RA	0.010
CG8605	CG8605 gene product from transcript CG8605-RA	0.010
Hs2st	heparan sulfate 2-O-sulfotransferase	0.010