IMP: Integrative Multi-species Prediction

Drosophila melanogaster

22 genes annotated in fly

reactive oxygen species metabolic process

The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "reactive oxygen species metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "reactive oxygen species metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Pvr	PDGF- and VEGF-receptor related	0.767	Mouse
Akt1	CG4006 gene product from transcript CG4006-RA	0.522
S6k	RPS6-p70-protein kinase	0.498
Atg1	Autophagy-specific gene 1	0.283
Pten	CG5671 gene product from transcript CG5671-RB	0.244
Pink1	PTEN-induced putative kinase 1	0.189	Human Zebrafish Mouse
Jra	Jun-related antigen	0.170
Dcr-2	Dicer-2	0.163
Trx-2	thioredoxin-2	0.162
scb	scab	0.159
CG6543	CG6543 gene product from transcript CG6543-RA	0.149
SdhB	Succinate dehydrogenase B	0.149
Pk61C	Protein kinase 61C	0.145
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.136
vkg	viking	0.130
Hsp22	Heat shock protein 22	0.129	Rat
VhaAC39	Vacuolar H[+]-ATPase C39 subunit	0.128
Sod	Superoxide dismutase	0.123
Hsp68	Heat shock protein 68	0.120
CG6429	CG6429 gene product from transcript CG6429-RA	0.119
Tbh	Tyramine beta hydroxylase	0.113
Act57B	Actin 57B	0.105
Fatp	Fatty acid (long chain) transport protein	0.103
dj-1beta	CG1349 gene product from transcript CG1349-RA	0.093
ird5	immune response deficient 5	0.092
CG13253	CG13253 gene product from transcript CG13253-RB	0.087
CG6783	CG6783 gene product from transcript CG6783-RC	0.084
kay	kayak	0.079
Sod2	Superoxide dismutase 2 (Mn)	0.077
p38b	CG7393 gene product from transcript CG7393-RA	0.074
drk	downstream of receptor kinase	0.073	Human
CG3004	CG3004 gene product from transcript CG3004-RA	0.073
Mhc	Myosin heavy chain	0.072
Rel	Relish	0.072
Actn	alpha actinin	0.070
Spargel	CG9809 gene product from transcript CG9809-RB	0.069
InR	Insulin-like receptor	0.068
dm	diminutive	0.068
chrb	charybde	0.068	Mouse
babo	baboon	0.066
CycJ	Cyclin J	0.065
Jafrac1	thioredoxin peroxidase 1	0.065
Lectin-galC1	Galactose-specific C-type lectin	0.061
Trim9	CG31721 gene product from transcript CG31721-RB	0.061
Thor	CG8846 gene product from transcript CG8846-RA	0.060
Hsp26	Heat shock protein 26	0.058	Rat
Prx2540-1	Peroxiredoxin 2540	0.058
nej	nejire	0.056
fln	flightin	0.056
CG15199	CG15199 gene product from transcript CG15199-RA	0.053
jeb	jelly belly	0.051
ninaA	neither inactivation nor afterpotential A	0.048
Trxr-1	Thioredoxin reductase-1	0.046
scyl	scylla	0.045	Mouse
chico	CG5686 gene product from transcript CG5686-RB	0.044
Gycalpha99B	Guanylyl cyclase alpha-subunit at 99B	0.044
CG2852	CG2852 gene product from transcript CG2852-RA	0.044
cln3	CG5582 gene product from transcript CG5582-RA	0.043
CG14290	CG14290 gene product from transcript CG14290-RB	0.043
Rab7	Rab-protein 7	0.042
klg	klingon	0.041
nwk	nervous wreck	0.041
park	parkin	0.040	Human
CG5794	CG5794 gene product from transcript CG5794-RB	0.040
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.039
Fmr1	CG6203 gene product from transcript CG6203-RC	0.039
LamC	Lamin C	0.037
CG10219	CG10219 gene product from transcript CG10219-RA	0.037
PIP5K59B	CG3682 gene product from transcript CG3682-RE	0.037
CG30410	CG30410 gene product from transcript CG30410-RB	0.037
repo	reversed polarity	0.037
LanA	Laminin A	0.037
Ras85D	Ras oncogene at 85D	0.036
sls	sallimus	0.036
Act88F	Actin 88F	0.036
Cat	Catalase	0.036
dos	daughter of sevenless	0.034
boss	bride of sevenless	0.034
Cg25C	Collagen type IV	0.034
Mpk2	CG5475 gene product from transcript CG5475-RB	0.033
Pp1alpha-96A	Protein phosphatase 1alpha at 96A	0.032
Prx2540-2	Peroxiredoxin 2540	0.032
p53	CG33336 gene product from transcript CG33336-RB	0.032	Human Mouse
trpml	transient receptor potential mucolipin	0.032
rut	rutabaga	0.032
Tdc2	Tyrosine decarboxylase 2	0.032
Hsp23	Heat shock protein 23	0.031	Rat
CG11876	CG11876 gene product from transcript CG11876-RA	0.030
Smox	Smad on X	0.030
RagA	CG11968 gene product from transcript CG11968-RA	0.030
yata	CG1973 gene product from transcript CG1973-RA	0.030
sra	sarah	0.030
kl-5	male fertility factor kl5	0.030
Pglym78	Phosphoglyceromutase	0.029
Rheb	CG1081 gene product from transcript CG1081-RA	0.029
Irc	Immune-regulated catalase	0.029
Mef2	Myocyte enhancer factor 2	0.029
CG9796	CG9796 gene product from transcript CG9796-RA	0.028
CG7998	CG7998 gene product from transcript CG7998-RA	0.027
Rac2	CG8556 gene product from transcript CG8556-RA	0.027
CG42629	CG42629 gene product from transcript CG42629-RB	0.027
PHGPx	CG12013 gene product from transcript CG12013-RC	0.027
CG1347	CG1347 gene product from transcript CG1347-RB	0.027
Mob2	CG11711 gene product from transcript CG11711-RC	0.027
CG2107	CG2107 gene product from transcript CG2107-RA	0.026
LanB2	Laminin B2	0.026
Mnt	CG13316 gene product from transcript CG13316-RD	0.026
Tom34	Translocase of outer membrane 34	0.025
Traf-like	TNF-receptor-associated factor-like	0.025
PGRP-LF	Peptidoglycan recognition protein LF	0.025
ci	cubitus interruptus	0.025
CG11151	CG11151 gene product from transcript CG11151-RA	0.025
alph	alphabet	0.025
tau	CG31057 gene product from transcript CG31057-RA	0.024
B-H1	BarH1	0.024
Nmdar1	NMDA receptor 1	0.024
cindr	CIN85 and CD2AP orthologue	0.024
CG42630	CG42630 gene product from transcript CG42630-RA	0.024
Dredd	Death related ced-3/Nedd2-like protein	0.024
Hsc70-5	Heat shock protein cognate 5	0.024
tomosyn	CG17762 gene product from transcript CG17762-RB	0.023
shn	schnurri	0.023
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.023
Cbl	CG7037 gene product from transcript CG7037-RB	0.023
Hsp27	Heat shock protein 27	0.023	Rat
RhoL	rho-like	0.023
RhoGDI	CG7823 gene product from transcript CG7823-RA	0.022
NLaz	Neural Lazarillo	0.022
EndoGI	Endonuclease G inhibitor	0.022
Dsk	Drosulfakinin	0.022
yki	yorkie	0.022
CG11368	CG11368 gene product from transcript CG11368-RA	0.021
Myo31DF	Myosin 31DF	0.021
TFAM	mitochondrial transcription factor A	0.021
Adk2	Adenylate kinase-2	0.021
CG16904	CG16904 gene product from transcript CG16904-RA	0.021
stnB	stoned B	0.020
Rho1	CG8416 gene product from transcript CG8416-RB	0.020
Ser	Serrate	0.020
WASp	CG1520 gene product from transcript CG1520-RA	0.020
Hsp60C	CG7235 gene product from transcript CG7235-RA	0.020
sev	sevenless	0.019	Fly
mbc	myoblast city	0.019
scu	scully	0.019
l(1)G0255	lethal (1) G0255	0.019
mRpL15	mitochondrial ribosomal protein L15	0.019
Mf	Myofilin	0.019
Hsp60	Heat shock protein 60	0.018
Oamb	Octopamine receptor in mushroom bodies	0.018
hth	homothorax	0.018
NPFR1	neuropeptide F receptor	0.018
CG14022	CG14022 gene product from transcript CG14022-RA	0.018
CG8790	CG8790 gene product from transcript CG8790-RB	0.018
bsk	basket	0.018	Fly
Indy	I'm not dead yet	0.017
CG9510	CG9510 gene product from transcript CG9510-RC	0.017
amd	alpha methyl dopa-resistant	0.017
CG7033	CG7033 gene product from transcript CG7033-RC	0.017
so	sine oculis	0.017
Socs36E	Suppressor of cytokine signaling at 36E	0.017
ImpL2	Ecdysone-inducible gene L2	0.017
Hand	CG18144 gene product from transcript CG18144-RA	0.017
CG6576	CG6576 gene product from transcript CG6576-RA	0.017
ex	expanded	0.017
E2f	E2F transcription factor	0.017
Hsp67Bc	Heat shock gene 67Bc	0.017
ND42	NADH:ubiquinone reductase 42kD subunit precursor	0.017
myoglianin	CG1838 gene product from transcript CG1838-RD	0.017
Dad	Daughters against dpp	0.017
CG32109	CG32109 gene product from transcript CG32109-RA	0.016
CG5149	CG5149 gene product from transcript CG5149-RA	0.016
byn	brachyenteron	0.016
CG1907	CG1907 gene product from transcript CG1907-RA	0.016
CrebB-17A	Cyclic-AMP response element binding protein B at 17A	0.016
Acon	Aconitase	0.016
mys	myospheroid	0.016
GstE3	Glutathione S transferase E3	0.016
CG6199	CG6199 gene product from transcript CG6199-RB	0.016
Spn27A	Serpin 27A	0.016
Rab5	Rab-protein 5	0.016
htl	heartless	0.016
ro	rough	0.016
beta4GalNAcTA	CG8536 gene product from transcript CG8536-RA	0.015
CG14757	CG14757 gene product from transcript CG14757-RA	0.015
hep	hemipterous	0.015
if	inflated	0.015
l(2)35Di	lethal (2) 35Di	0.015
Crc	Calreticulin	0.015
Df31	Decondensation factor 31	0.015
nord	CG30418 gene product from transcript CG30418-RA	0.015
Pvf2	PDGF- and VEGF-related factor 2	0.015
mRpL2	mitochondrial ribosomal protein L2	0.015
ome	omega	0.015
CG8193	CG8193 gene product from transcript CG8193-RA	0.014
CalpA	Calpain-A	0.014
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.014
imd	immune deficiency	0.014
Treh	Trehalase	0.014
CG9090	CG9090 gene product from transcript CG9090-RA	0.014
CG8443	CG8443 gene product from transcript CG8443-RA	0.014
CG14715	CG14715 gene product from transcript CG14715-RA	0.014
wun	wunen	0.014
Pkc98E	Protein C kinase 98E	0.014
Aats-ser	Seryl-tRNA synthetase	0.014
regucalcin	CG1803 gene product from transcript CG1803-RA	0.014
CG30409	CG30409 gene product from transcript CG30409-RA	0.014
CCKLR-17D1	CCK-like receptor at 17D1	0.014
Cf2	Chorion factor 2	0.014
l(2)35Bg	lethal (2) 35Bg	0.014
CG11327	CG11327 gene product from transcript CG11327-RA	0.014
cup	CG11181 gene product from transcript CG11181-RB	0.014
CG6084	CG6084 gene product from transcript CG6084-RB	0.014
CYLD	cylindromatosis	0.013
Mst77F	Male-specific transcript 77F	0.013
PNUTS	CG33526 gene product from transcript CG33526-RD	0.013
l(2)k14710	lethal (2) k14710	0.013
inx7	innexin 7	0.013
Patr-1	Protein associated with topo II related - 1	0.013
CG6180	CG6180 gene product from transcript CG6180-RA	0.013
CG16718	CG16718 gene product from transcript CG16718-RA	0.013
rols	rolling pebbles	0.013
Fkbp13	CG9847 gene product from transcript CG9847-RC	0.013
alpha-Man-II	alpha Mannosidase II	0.013
Vps16A	Vacuolar protein sorting 16A	0.013
Atg18	Autophagy-specific gene 18	0.013
CG30427	CG30427 gene product from transcript CG30427-RC	0.013
Fbxl4	F box and leucine-rich-repeat gene 4	0.013
CG6734	CG6734 gene product from transcript CG6734-RA	0.013
CG13890	CG13890 gene product from transcript CG13890-RA	0.013
Iap2	Inhibitor of apoptosis 2	0.013
CG6455	CG6455 gene product from transcript CG6455-RC	0.013
CG1516	CG1516 gene product from transcript CG1516-RP	0.013
Ser7	CG2045 gene product from transcript CG2045-RA	0.012
gig	gigas	0.012
TpnC41C	Troponin C at 41C	0.012
CG4802	CG4802 gene product from transcript CG4802-RA	0.012
Ilk	Integrin linked kinase	0.012
daw	dawdle	0.012	Human
betaInt-nu	beta[nu] integrin	0.012
CG9773	CG9773 gene product from transcript CG9773-RA	0.012
Fhos	CG42610 gene product from transcript CG42610-RC	0.012
CG9581	CG9581 gene product from transcript CG9581-RA	0.012
sm	smooth	0.012
mav	maverick	0.012
Ank2	Ankyrin 2	0.012
CycH	Cyclin H	0.012
CG6412	CG6412 gene product from transcript CG6412-RA	0.012
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.012
CG4461	CG4461 gene product from transcript CG4461-RA	0.012
CG12171	CG12171 gene product from transcript CG12171-RA	0.012
Dab	Disabled	0.012
CG11242	CG11242 gene product from transcript CG11242-RA	0.012
fh	frataxin homolog	0.012
cher	cheerio	0.012
CG11267	CG11267 gene product from transcript CG11267-RA	0.012
sima	similar	0.012
Actbeta	Activin-beta	0.012	Human
Trap1	CG3152 gene product from transcript CG3152-RA	0.012
wun2	wunen-2	0.012
svp	seven up	0.012
GlcAT-P	CG6207 gene product from transcript CG6207-RC	0.011
magu	CG2264 gene product from transcript CG2264-RD	0.011
Odc2	Ornithine decarboxylase 2	0.011
Eip71CD	Ecdysone-induced protein 28/29kD	0.011
ref(2)P	refractory to sigma P	0.011
PGRP-LE	Peptidoglycan recognition protein LE	0.011
CG42863	CG42863 gene product from transcript CG42863-RB	0.011
torp4a	CG3024 gene product from transcript CG3024-RA	0.011
Dip2	Dorsal interacting protein 2	0.011
Prat2	Phosphoribosylamidotransferase 2	0.011
CG1927	CG1927 gene product from transcript CG1927-RA	0.011
CG34172	CG34172 gene product from transcript CG34172-RA	0.011
CG34168	CG34168 gene product from transcript CG34168-RA	0.011
sea	scheggia	0.011
gho	ghost	0.011
nemy	no extended memory	0.011
DopEcR	CG18314 gene product from transcript CG18314-RB	0.011
CG5282	CG5282 gene product from transcript CG5282-RA	0.011
2mit	CG42573 gene product from transcript CG42573-RA	0.011
Sgf11	CG13379 gene product from transcript CG13379-RB	0.011
Mipp1	Multiple inositol polyphosphate phosphatase 1	0.011
ptc	patched	0.011
Tm2	Tropomyosin 2	0.011
mol	moladietz	0.011
Cyp18a1	Cytochrome P450-18a1	0.011
CG31633	CG31633 gene product from transcript CG31633-RA	0.011
Pkcdelta	Protein kinase C delta	0.011
CG5385	CG5385 gene product from transcript CG5385-RA	0.011
pasha	partner of drosha	0.011
sip2	septin interacting protein 2	0.011
Pld	Phospholipase D	0.011
Gpo-1	Glycerophosphate oxidase-1	0.011
pirk	poor Imd response upon knock-in	0.010
CG5482	CG5482 gene product from transcript CG5482-RA	0.010
EcR	Ecdysone receptor	0.010
Tm1	Tropomyosin 1	0.010
mib2	mind bomb 2	0.010
CG7526	CG7526 gene product from transcript CG7526-RC	0.010
nimC4	nimrod C4	0.010
Sh3beta	CG8582 gene product from transcript CG8582-RD	0.010
pst	pastrel	0.010
slbo	slow border cells	0.010
CG11825	CG11825 gene product from transcript CG11825-RA	0.010
rt	rotated abdomen	0.010
BG4	CG12297 gene product from transcript CG12297-RA	0.010
l(3)82Fd	CG32464 gene product from transcript CG32464-RR	0.010
foxo	forkhead box, sub-group O	0.010	Mouse