IMP: Integrative Multi-species Prediction

Drosophila melanogaster

24 genes annotated in fly

positive regulation of proteolysis involved in cellular protein catabolic process

GO:1903052

Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of proteolysis involved in cellular protein catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of proteolysis involved in cellular protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Rpn6	Proteasome p44.5 subunit	0.568
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.360
dsh	dishevelled	0.357	Human
CG4673	CG4673 gene product from transcript CG4673-RB	0.339
Uch-L3	Ubiquitin C-terminal hydrolase	0.316
cav	caravaggio	0.304
CG13349	CG13349 gene product from transcript CG13349-RA	0.255
Pros25	Proteasome 25kD subunit	0.217
CG12321	CG12321 gene product from transcript CG12321-RA	0.216
Pros35	Proteasome 35kD subunit	0.203
Mov34	CG3416 gene product from transcript CG3416-RA	0.200
tefu	telomere fusion	0.199
Prosbeta7	Proteasome beta7 subunit	0.197
CG5384	CG5384 gene product from transcript CG5384-RA	0.147
Tbp-1	Tat-binding protein-1	0.139
Rpt1	CG1341 gene product from transcript CG1341-RA	0.131
ida	imaginal discs arrested	0.128
dos	daughter of sevenless	0.122
Cul-5	Cullin-5	0.117
dlt	discs lost	0.114
CycB	Cyclin B	0.108
stan	starry night	0.108
msps	mini spindles	0.107
Rpn9	CG10230 gene product from transcript CG10230-RB	0.104
hpo	hippo	0.102
Rpt3	CG16916 gene product from transcript CG16916-RA	0.098
RYBP	Ring and YY1 Binding Protein	0.096
Rpn3	Regulatory particle non-ATPase 3	0.092
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.088
Rpn1	CG7762 gene product from transcript CG7762-RA	0.081
cdc23	CG2508 gene product from transcript CG2508-RA	0.081
frtz	fritz	0.081
CG2046	CG2046 gene product from transcript CG2046-RA	0.077
krz	kurtz	0.072
cmet	CENP-meta	0.071
Pcaf	CG4107 gene product from transcript CG4107-RA	0.068
slmb	supernumerary limbs	0.065
G9a	CG2995 gene product from transcript CG2995-RA	0.062
Act5C	Actin 5C	0.061
CSN4	COP9 complex homolog subunit 4	0.060
CycA	Cyclin A	0.060
Trim9	CG31721 gene product from transcript CG31721-RB	0.058	Mouse
drk	downstream of receptor kinase	0.057
CG30382	CG30382 gene product from transcript CG30382-RB	0.057
Pros54	Proteasome 54kD subunit	0.055
Prosbeta3	Proteasome beta3 subunit	0.054
Fcp1	CG12252 gene product from transcript CG12252-RA	0.054
Pros45	CG1489 gene product from transcript CG1489-RA	0.052
Rpt4	CG3455 gene product from transcript CG3455-RA	0.050
Orc2	Origin recognition complex subunit 2	0.047
Klp10A	CG1453 gene product from transcript CG1453-RA	0.046
wdb	widerborst	0.045
UbcD2	Ubiquitin conjugating enzyme 2	0.043
smo	smoothened	0.043
Akt1	CG4006 gene product from transcript CG4006-RA	0.043	Mouse
Rpn7	CG5378 gene product from transcript CG5378-RA	0.041
Pros26.4	Proteasome 26S subunit subunit 4 ATPase	0.041
Prosbeta1	Proteasome beta1 subunit	0.040
kermit	CG11546 gene product from transcript CG11546-RB	0.040
Plap	Phospholipase A2 activator protein	0.040
Mlf	Myelodysplasia/myeloid leukemia factor	0.040
shtd	shattered	0.040
Mob4	CG3403 gene product from transcript CG3403-RA	0.039
Ras85D	Ras oncogene at 85D	0.039
fz	frizzled	0.038
chb	chromosome bows	0.038
DJ-1alpha	CG6646 gene product from transcript CG6646-RA	0.038
Rpn11	CG18174 gene product from transcript CG18174-RA	0.038
CSN3	COP9 complex homolog subunit 3	0.036
spi	spitz	0.036
Cenp-C	CG31258 gene product from transcript CG31258-RA	0.036
lgs	legless	0.035
Ho	Heme oxygenase	0.035
fz2	frizzled 2	0.034
ex	expanded	0.033
skpA	CG16983 gene product from transcript CG16983-RD	0.033
jar	jaguar	0.033
brat	brain tumor	0.033
dap	dacapo	0.032
CSN1b	COP9 complex homolog subunit 1 b	0.032
TER94	CG2331 gene product from transcript CG2331-RA	0.030
gbb	glass bottom boat	0.030
polo	CG12306 gene product from transcript CG12306-RA	0.030	Human
Rca1	Regulator of cyclin A1	0.029
poly	CG9829 gene product from transcript CG9829-RB	0.029
lap	like-AP180	0.028
CG33129	CG33129 gene product from transcript CG33129-RE	0.028
SF2	CG6987 gene product from transcript CG6987-RA	0.028
cal1	chromosome alignment defect 1	0.027
Cul-2	Cullin-2	0.027
CG5510	CG5510 gene product from transcript CG5510-RA	0.026
CSN8	COP9 complex homolog subunit 8	0.026
mats	mob as tumor suppressor	0.026
fzy	fizzy	0.026
Chro	Chromator	0.025
Sir2	CG5216 gene product from transcript CG5216-RA	0.025
cdc16	CG6759 gene product from transcript CG6759-RA	0.025
drosha	CG8730 gene product from transcript CG8730-RA	0.025
l(1)dd4	lethal (1) discs degenerate 4	0.025
loqs	loquacious	0.024
Top1	Topoisomerase 1	0.023
jub	Ajuba LIM protein	0.023
Mad	Mothers against dpp	0.023
vih	vihar	0.023
insc	inscuteable	0.023
CG11347	CG11347 gene product from transcript CG11347-RE	0.022
barr	barren	0.022
CG6859	CG6859 gene product from transcript CG6859-RA	0.022
trbl	tribbles	0.022
Rpn2	CG11888 gene product from transcript CG11888-RA	0.022
swa	swallow	0.022
Drp1	Dynamin related protein 1	0.022
wee	CG4488 gene product from transcript CG4488-RA	0.022
LIMK1	LIM-kinase1	0.021
Nuf2	CG8902 gene product from transcript CG8902-RA	0.021
CG6454	CG6454 gene product from transcript CG6454-RC	0.021
Nipped-A	CG33554 gene product from transcript CG33554-RE	0.021
dlp	dally-like	0.021
Dref	DNA replication-related element factor	0.021
Ulp1	CG12359 gene product from transcript CG12359-RA	0.021
granny-smith	granny smith	0.020
Clk	Clock	0.020
ttv	tout-velu	0.020
fs(1)Ya	female sterile (1) Young arrest	0.019
shg	shotgun	0.019
l(2)35Bg	lethal (2) 35Bg	0.019
hipk	homeodomain interacting protein kinase	0.019
bsk	basket	0.019
Psf2	CG18013 gene product from transcript CG18013-RA	0.019
ft	fat	0.018
CG32556	CG32556 gene product from transcript CG32556-RB	0.018
CG1172	CG1172 gene product from transcript CG1172-RA	0.018
S6k	RPS6-p70-protein kinase	0.018
CG9304	CG9304 gene product from transcript CG9304-RA	0.018
mi	minus	0.018
in	inturned	0.018
dgo	diego	0.018
Sse	Separase	0.017
CG9801	CG9801 gene product from transcript CG9801-RC	0.017
dbo	diablo	0.017
ru	roughoid	0.017
rl	rolled	0.017
dlg1	discs large 1	0.017
crol	crooked legs	0.017
tws	twins	0.017
alphaTub67C	alpha-Tubulin at 67C	0.017
Cap-G	CG34438 gene product from transcript CG34438-RF	0.017
brm	brahma	0.016
fbl	fumble	0.016
Top2	Topoisomerase 2	0.016
sw	short wing	0.016
arm	armadillo	0.016
step	steppke	0.016
Ube3a	Ubiquitin protein ligase E3A	0.016
coil	coilin	0.016
pie	pineapple eye	0.016
Uch	Ubiquitin carboxy-terminal hydrolase	0.016
wg	wingless	0.016
MtnB	Metallothionein B	0.016
mts	microtubule star	0.015
fliI	flightless I	0.015
Aats-met	Methionyl-tRNA synthetase	0.015
mth	methuselah	0.015
Mcm10	Sensitized chromosome inheritance modifier 19	0.015
Dscam	Down syndrome cell adhesion molecule	0.015
bel	belle	0.015
jumu	jumeau	0.015
disp	dispatched	0.015
Mi-2	CG8103 gene product from transcript CG8103-RA	0.015
Psa	Puromycin sensitive aminopeptidase	0.014
Dhod	Dihydroorotate dehydrogenase	0.014
CG15730	CG15730 gene product from transcript CG15730-RA	0.014
Z600	CG17962 gene product from transcript CG17962-RA	0.014
Gga	CG3002 gene product from transcript CG3002-RB	0.014
CG1103	CG1103 gene product from transcript CG1103-RA	0.014
Bre1	CG10542 gene product from transcript CG10542-RA	0.014
arr	arrow	0.014
Taspase1	Taspase 1	0.014
trc	tricornered	0.014
CG42251	CG42251 gene product from transcript CG42251-RC	0.014
TppII	tripeptidyl-peptidase II	0.014
CG9866	CG9866 gene product from transcript CG9866-RA	0.014
ATP7	CG1886 gene product from transcript CG1886-RB	0.014
danr	distal antenna-related	0.014
A3-3	CG11405 gene product from transcript CG11405-RA	0.013
Kap-alpha3	karyopherin alpha3	0.013
sano	serrano	0.013
ago	archipelago	0.013
CG2147	CG2147 gene product from transcript CG2147-RA	0.013
CG1908	CG1908 gene product from transcript CG1908-RA	0.013
Cdc37	CG12019 gene product from transcript CG12019-RA	0.013
fry	furry	0.013
milt	milton	0.013
rux	roughex	0.013
fj	four-jointed	0.013
CG8329	CG8329 gene product from transcript CG8329-RA	0.013
CG17528	CG17528 gene product from transcript CG17528-RC	0.013
neur	neuralized	0.013
CG15828	CG15828 gene product from transcript CG15828-RC	0.013
Rho1	CG8416 gene product from transcript CG8416-RB	0.013
Ras64B	Ras oncogene at 64B	0.013
ci	cubitus interruptus	0.013
Mob2	CG11711 gene product from transcript CG11711-RC	0.012
pasha	partner of drosha	0.012
wb	wing blister	0.012
Ufd1-like	Ubiquitin fusion-degradation 1-like	0.012
rab3-GAP	CG7061 gene product from transcript CG7061-RA	0.012
spas	spastin	0.012
Cip4	CG15015 gene product from transcript CG15015-RA	0.012
Mtl	Mig-2-like	0.012
mof	males absent on the first	0.012
Zyx102EF	CG32018 gene product from transcript CG32018-RA	0.012
MAN1	CG3167 gene product from transcript CG3167-RA	0.012
Su(var)2-10	Suppressor of variegation 2-10	0.012	Mouse
dco	discs overgrown	0.012
bun	bunched	0.012
tsh	teashirt	0.012
dik	diskette	0.012
p47	CG11139 gene product from transcript CG11139-RA	0.012
sl	small wing	0.012
mus304	mutagen-sensitive 304	0.012
CG14614	CG14614 gene product from transcript CG14614-RA	0.012
CG31108	CG31108 gene product from transcript CG31108-RA	0.012
CG5555	CG5555 gene product from transcript CG5555-RA	0.012
Pros28.1	Proteasome 28kD subunit 1	0.012
CG8526	CG8526 gene product from transcript CG8526-RA	0.012
CG8043	CG8043 gene product from transcript CG8043-RA	0.011
fz4	frizzled 4	0.011
Su(H)	Suppressor of Hairless	0.011
CG9855	CG9855 gene product from transcript CG9855-RA	0.011
Trf4-1	CG11265 gene product from transcript CG11265-RE	0.011
Cks85A	Cyclin-dependent kinase subunit 85A	0.011
CG14275	CG14275 gene product from transcript CG14275-RA	0.011
cort	cortex	0.011
CG12001	CG12001 gene product from transcript CG12001-RA	0.011
CG6707	CG6707 gene product from transcript CG6707-RA	0.011
egr	eiger	0.011
CG5674	CG5674 gene product from transcript CG5674-RB	0.011
yata	CG1973 gene product from transcript CG1973-RA	0.011
dm	diminutive	0.011
CG8979	CG8979 gene product from transcript CG8979-RC	0.011
corto	CG2530 gene product from transcript CG2530-RA	0.011
Pros26	Proteasome 26kD subunit	0.011
Sac1	CG9128 gene product from transcript CG9128-RB	0.011
woc	without children	0.011
Bj1	Bj1 protein	0.011
Gef64C	Guanine nucleotide exchange factor GEF64C	0.011
Spc105R	Spc105-related	0.011
Irk2	Inwardly rectifying potassium channel 2	0.011
CG9572	CG9572 gene product from transcript CG9572-RA	0.011
ball	ballchen	0.011
trpml	transient receptor potential mucolipin	0.011
l(2)k16918	lethal (2) k16918	0.011
Df31	Decondensation factor 31	0.011
coro	CG9446 gene product from transcript CG9446-RC	0.011
CG3781	CG3781 gene product from transcript CG3781-RA	0.011
lkb1	CG9374 gene product from transcript CG9374-RJ	0.011
E(bx)	Enhancer of bithorax	0.011
CG10158	CG10158 gene product from transcript CG10158-RA	0.010
Oda	Ornithine decarboxylase antizyme	0.010
Gug	Grunge	0.010
nudE	CG8104 gene product from transcript CG8104-RB	0.010
Prosalpha7	Proteasome alpha7 subunit	0.010
stg	string	0.010
CG11286	CG11286 gene product from transcript CG11286-RA	0.010
HLH106	Helix loop helix protein 106	0.010
CG9323	CG9323 gene product from transcript CG9323-RA	0.010
dbr	debra	0.010
CG2218	CG2218 gene product from transcript CG2218-RA	0.010
snama	something that sticks like glue	0.010
CG3016	CG3016 gene product from transcript CG3016-RA	0.010
CG9934	CG9934 gene product from transcript CG9934-RB	0.010
CG4603	CG4603 gene product from transcript CG4603-RA	0.010