IMP: Integrative Multi-species Prediction

Drosophila melanogaster

34 genes annotated in fly

establishment or maintenance of apical basal cell polarity

Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "establishment or maintenance of apical basal cell polarity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "establishment or maintenance of apical basal cell polarity" (in gray)

Name	Description	Probability	Func Analog Organism
Moe	Moesin	0.937
ds	dachsous	0.728
crb	crumbs	0.699
l(2)gl	lethal (2) giant larvae	0.679	Mouse
trc	tricornered	0.597
Rab5	Rab-protein 5	0.571
Rab11	Rab-protein 11	0.559
cora	coracle	0.537
kst	karst	0.531
trpl	trp-like	0.527
Sop2	Suppressor of profilin 2	0.525
arm	armadillo	0.514
aPKC	atypical protein kinase C	0.481
frc	fringe connection	0.453
dlg1	discs large 1	0.419	Mouse
Cdc42	CG12530 gene product from transcript CG12530-RA	0.412	Mouse
eya	eyes absent	0.392	Mouse
Chc	Clathrin heavy chain	0.389
Rala	Ras-related protein	0.388	Fly
kug	kugelei	0.371
par-1	CG8201 gene product from transcript CG8201-RA	0.343
cpa	capping protein alpha	0.302
trp	transient receptor potential	0.263
Khc	Kinesin heavy chain	0.261
sktl	skittles	0.256
Syx5	Syntaxin 5	0.252
Lis-1	Lissencephaly-1	0.242
par-6	CG5884 gene product from transcript CG5884-RA	0.230
ft	fat	0.224
dia	diaphanous	0.203
yki	yorkie	0.192
sqh	spaghetti squash	0.182
Rac1	CG2248 gene product from transcript CG2248-RA	0.180
Vang	Van Gogh	0.177	Mouse
Shc	SHC-adaptor protein	0.176
pk	prickle	0.172	Mouse
klar	klarsicht	0.171
Dmn	Dynamitin	0.170
Syx7	Syntaxin 7	0.170
hpo	hippo	0.165
fj	four-jointed	0.165
nct	nicastrin	0.163
lkb1	CG9374 gene product from transcript CG9374-RJ	0.157
fz	frizzled	0.152
stan	starry night	0.145
wg	wingless	0.138
beta-Spec	beta Spectrin	0.125
bun	bunched	0.124
Jra	Jun-related antigen	0.121
baz	bazooka	0.119
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.110
shg	shotgun	0.110
Dhc64C	Dynein heavy chain 64C	0.108
VhaAC39	Vacuolar H[+]-ATPase C39 subunit	0.104
Arr2	Arrestin 2	0.099
Sgt1	CG9617 gene product from transcript CG9617-RA	0.099
ric8a	CG15797 gene product from transcript CG15797-RA	0.098
raps	rapsynoid	0.097
vas	vasa	0.097
sec23	CG1250 gene product from transcript CG1250-RA	0.097
Npc1a	Niemann-Pick type C-1a	0.094
Dlic	Dynein light intermediate chain	0.094
CG13144	CG13144 gene product from transcript CG13144-RA	0.090
Arp87C	Actin-related protein 87C	0.090
dome	domeless	0.089
Fas2	Fasciclin 2	0.089
ttk	tramtrack	0.084	Fly
kuz	kuzbanian	0.081
CG34168	CG34168 gene product from transcript CG34168-RA	0.079
vib	vibrator	0.079
Wnt4	Wnt oncogene analog 4	0.078
Rbsn-5	Rabenosyn-5	0.074
spi	spitz	0.073
Krn	Keren	0.072
alpha-Spec	alpha Spectrin	0.070
Gug	Grunge	0.064
sano	serrano	0.064
egl	egalitarian	0.063
D	Dichaete	0.063
flr	flare	0.061
Hph	HIF prolyl hydroxylase	0.060
ovo	CG6824 gene product from transcript CG6824-RE	0.060
vps2	CG14542 gene product from transcript CG14542-RA	0.059
ex	expanded	0.058
cic	capicua	0.057
Xpd	Xeroderma pigmentosum D	0.057
btz	barentsz	0.056
vps24	Charged multivesicular body protein 3	0.055
CalpB	Calpain-B	0.055
stumps	CG31317 gene product from transcript CG31317-RC	0.054
pnt	pointed	0.054
CadN	Cadherin-N	0.053
bowl	brother of odd with entrails limited	0.051
Nrx-IV	Neurexin IV	0.050
Vps28	Vacuolar protein sorting 28	0.048
msn	misshapen	0.048
TSG101	tumor suppressor protein 101	0.048
Usf	CG17592 gene product from transcript CG17592-RB	0.047
fry	furry	0.047
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.047
schlank	CG3576 gene product from transcript CG3576-RB	0.046
rhea	CG6831 gene product from transcript CG6831-RA	0.046
CG10103	CG10103 gene product from transcript CG10103-RA	0.045
wts	warts	0.044
pex1	peroxin 1	0.044
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.044
dsh	dishevelled	0.042
bcd	bicoid	0.042
rok	Rho-kinase	0.042
Patj	CG12021 gene product from transcript CG12021-RC	0.042
her	hermaphrodite	0.041
wdb	widerborst	0.039
CG32556	CG32556 gene product from transcript CG32556-RB	0.038
drm	drumstick	0.038
dbo	diablo	0.037
MYPT-75D	CG6896 gene product from transcript CG6896-RA	0.036
gho	ghost	0.035
CG1115	CG1115 gene product from transcript CG1115-RA	0.035
Appl	beta amyloid protein precursor-like	0.035
nudE	CG8104 gene product from transcript CG8104-RB	0.034
cdi	center divider	0.033
Kap-alpha3	karyopherin alpha3	0.033
aop	anterior open	0.033
Syx16	Syntaxin 16	0.033
tsh	teashirt	0.033
ftz-f1	ftz transcription factor 1	0.032
Spn77Ba	Serpin 77Ba	0.032
if	inflated	0.030
sec6	CG5341 gene product from transcript CG5341-RA	0.030
Wnt5	Wnt oncogene analog 5	0.030
fs(1)M3	female sterile (1) M3	0.029
CG3529	CG3529 gene product from transcript CG3529-RB	0.029
gammaCop	gamma-coatomer protein	0.029
fng	fringe	0.029
gish	gilgamesh	0.029
CG31740	CG31740 gene product from transcript CG31740-RA	0.028
CG4699	CG4699 gene product from transcript CG4699-RJ	0.028
endos	endosulfine	0.028
G-ialpha65A	G protein alphai subunit 65A	0.028
car	carnation	0.028
G-oalpha47A	G protein oalpha 47A	0.028
ninaC	neither inactivation nor afterpotential C	0.027
CG13994	CG13994 gene product from transcript CG13994-RA	0.027
tsr	twinstar	0.026
wb	wing blister	0.026
dgo	diego	0.026
sec8	CG2095 gene product from transcript CG2095-RA	0.026
vvl	ventral veins lacking	0.025
Crag	Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein	0.025
mys	myospheroid	0.025
zip	zipper	0.025
Ggamma1	G protein gamma 1	0.025
grk	gurken	0.024
Tak1	TGF-beta activated kinase 1	0.024
raw	CG12437 gene product from transcript CG12437-RB	0.024
trx	trithorax	0.024
salm	spalt major	0.024
CG6664	CG6664 gene product from transcript CG6664-RC	0.024
stck	steamer duck	0.024
lqfR	liquid facets-Related	0.023
kay	kayak	0.023
CG6116	CG6116 gene product from transcript CG6116-RA	0.023
bdg	bedraggled	0.023
sd	scalloped	0.023
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.023
mop	myopic	0.022
l(2)06496	lethal (2) 06496	0.022
l(2)35Bg	lethal (2) 35Bg	0.022
Synd	Syndapin	0.022
GckIII	Germinal centre kinase III	0.022
grh	grainy head	0.021
MESR6	Misexpression suppressor of ras 6	0.021
Upf2	CG2253 gene product from transcript CG2253-RA	0.021
sno	strawberry notch	0.021
Cenp-C	CG31258 gene product from transcript CG31258-RA	0.021
Nrt	Neurotactin	0.020
Rbcn-3B	Rabconnectin-3B	0.020
Mmp2	Matrix metalloproteinase 2	0.020
e(y)3	enhancer of yellow 3	0.020
bif	bifocal	0.020
CG9139	CG9139 gene product from transcript CG9139-RA	0.020
Tollo	CG6890 gene product from transcript CG6890-RA	0.020
bnl	branchless	0.020
stau	staufen	0.020
lft	lowfat	0.020
boi	brother of iHog	0.020
puc	puckered	0.019
Cyp18a1	Cytochrome P450-18a1	0.019
wkd	whacked	0.019
scrib	scribbled	0.019
mats	mob as tumor suppressor	0.019
CG6954	CG6954 gene product from transcript CG6954-RB	0.019
pex13	peroxin 13	0.019
CG14894	CG14894 gene product from transcript CG14894-RA	0.019
CG32647	CG32647 gene product from transcript CG32647-RB	0.018
sav	salvador	0.018
sgg	shaggy	0.018
CHMP2B	Charged multivesicular body protein 2b	0.018
Su(H)	Suppressor of Hairless	0.018
BicD	Bicaudal D	0.018
Cap-G	CG34438 gene product from transcript CG34438-RF	0.018
toy	twin of eyeless	0.018
CG15861	CG15861 gene product from transcript CG15861-RA	0.018
CG8709	CG8709 gene product from transcript CG8709-RK	0.018
Arpc3B	CG8936 gene product from transcript CG8936-RA	0.018
Rab2	Rab-protein 2	0.018
Cog7	CG31040 gene product from transcript CG31040-RA	0.017
bab2	CG9102 gene product from transcript CG9102-RA	0.017
ATbp	(A+T)-stretch binding protein	0.017
asl	asterless	0.017
pan	pangolin	0.017
Vhl	von Hippel-Lindau	0.017
ru	roughoid	0.017
Ctr1B	Copper transporter 1B	0.017
CG13032	CG13032 gene product from transcript CG13032-RA	0.017
RYBP	Ring and YY1 Binding Protein	0.017
CoRest	CG42687 gene product from transcript CG42687-RC	0.017
mwh	multiple wing hairs	0.016
LIMK1	LIM-kinase1	0.016
bond	james bond	0.016
Vha55	Vacuolar H[+]-ATPase 55kD B subunit	0.016
mew	multiple edematous wings	0.016
CG17184	CG17184 gene product from transcript CG17184-RB	0.016
Fs	Follistatin	0.016
endoB	endophilin B	0.016
mfrn	mitoferrin	0.016
SoxN	SoxNeuro	0.016
argos	CG4531 gene product from transcript CG4531-RA	0.016
CG31352	CG31352 gene product from transcript CG31352-RA	0.016
CG8329	CG8329 gene product from transcript CG8329-RA	0.016
Psn	Presenilin	0.016
CG4328	CG4328 gene product from transcript CG4328-RB	0.015
Mi-2	CG8103 gene product from transcript CG8103-RA	0.015
CG6443	CG6443 gene product from transcript CG6443-RA	0.015
CG8735	CG8735 gene product from transcript CG8735-RA	0.015
Tm1	Tropomyosin 1	0.015
Chmp1	CG4108 gene product from transcript CG4108-RA	0.015
Rheb	CG1081 gene product from transcript CG1081-RA	0.015
Nhe2	Na[+]/H[+] hydrogen exchanger 2	0.015
drk	downstream of receptor kinase	0.015
Sin1	SAPK-interacting protein 1	0.015
tll	tailless	0.015
mod(r)	modifier of rudimentary	0.015
CG17746	CG17746 gene product from transcript CG17746-RA	0.015
mask	multiple ankyrin repeats single KH domain	0.015
sinah	sina homologue	0.014
Rh3	Rhodopsin 3	0.014
TwdlQ	TweedleQ	0.014
bsk	basket	0.014
Gbeta13F	G protein beta-subunit 13F	0.014
CG32528	CG32528 gene product from transcript CG32528-RA	0.014
bru	brunelleschi	0.014
otk	off-track	0.014	Mouse
CG14712	CG14712 gene product from transcript CG14712-RA	0.014
ImpE1	Ecdysone-inducible gene E1	0.014
CG34324	CG34324 gene product from transcript CG34324-RA	0.014
ssh	slingshot	0.014
app	approximated	0.014
Sox21b	CG32139 gene product from transcript CG32139-RA	0.014
CG13636	CG13636 gene product from transcript CG13636-RB	0.014
Ero1L	Endoplasmic reticulum oxidoreductin-1-like	0.014
trol	terribly reduced optic lobes	0.014
mol	moladietz	0.014
CG4091	CG4091 gene product from transcript CG4091-RA	0.013
CG42251	CG42251 gene product from transcript CG42251-RC	0.013
nmo	nemo	0.013
Cul-5	Cullin-5	0.013
slbo	slow border cells	0.013
Rab23	CG2108 gene product from transcript CG2108-RA	0.013
A3-3	CG11405 gene product from transcript CG11405-RA	0.013
CG11984	CG11984 gene product from transcript CG11984-RD	0.013
alphaTub67C	alpha-Tubulin at 67C	0.013
R	Roughened	0.013
melt	melted	0.013
Rpb4	CG33520 gene product from transcript CG33520-RF	0.013
Tsp39D	Tetraspanin 39D	0.013
CG11178	CG11178 gene product from transcript CG11178-RA	0.013
Pros54	Proteasome 54kD subunit	0.013
Hr96	Hormone receptor-like in 96	0.013
4EHP	CG33100 gene product from transcript CG33100-RA	0.013
hb	hunchback	0.013
stl	stall	0.013
Ady43A	CG1851 gene product from transcript CG1851-RA	0.013
in	inturned	0.013
Fim	Fimbrin	0.013
CG14275	CG14275 gene product from transcript CG14275-RA	0.012
CG33169	CG33169 gene product from transcript CG33169-RA	0.012
Sln	Silnoon	0.012
Cirl	CG8639 gene product from transcript CG8639-RC	0.012
alphaTub84B	alpha-Tubulin at 84B	0.012
hth	homothorax	0.012
rtv	retroactive	0.012
fs(1)N	female sterile (1) Nasrat	0.012
Syx13	Syntaxin 13	0.012	Fly
Sucb	CG10622 gene product from transcript CG10622-RA	0.012
CG4213	CG4213 gene product from transcript CG4213-RA	0.012
UBL3	CG9038 gene product from transcript CG9038-RC	0.012
CG13894	CG13894 gene product from transcript CG13894-RA	0.012
Brf	CG31256 gene product from transcript CG31256-RA	0.012
bap	bagpipe	0.011
fs(1)K10	female sterile (1) K10	0.011
Rbp9	RNA-binding protein 9	0.011
egh	egghead	0.011
Blimp-1	CG5249 gene product from transcript CG5249-RA	0.011
CG17265	CG17265 gene product from transcript CG17265-RA	0.011
twf	twinfilin	0.011
asun	asunder	0.011
ns2	nucleostemin 2	0.011
Lip3	CG8823 gene product from transcript CG8823-RA	0.011
oaf	out at first	0.011
Jupiter	CG31363 gene product from transcript CG31363-RD	0.011
sdt	stardust	0.011
lbl	ladybird late	0.011
CTCF	CG8591 gene product from transcript CG8591-RA	0.011
CG7924	CG7924 gene product from transcript CG7924-RA	0.011
CG42389	CG42389 gene product from transcript CG42389-RE	0.011
trpm	CG34123 gene product from transcript CG34123-RG	0.011
fkh	fork head	0.011
tkv	thickveins	0.011
Ctr1A	Copper transporter 1A	0.011
MtnB	Metallothionein B	0.011
ttv	tout-velu	0.011
krz	kurtz	0.011
Pitslre	CG4268 gene product from transcript CG4268-RA	0.011
twe	twine	0.011
Cpr92F	Cuticular protein 92F	0.011
pck	pickel	0.011
CG10943	CG10943 gene product from transcript CG10943-RA	0.011
CG9416	CG9416 gene product from transcript CG9416-RA	0.011
flower	CG6151 gene product from transcript CG6151-RA	0.011
CG18769	CG18769 gene product from transcript CG18769-RB	0.010
CG3016	CG3016 gene product from transcript CG3016-RA	0.010
kkv	krotzkopf verkehrt	0.010
CG6361	CG6361 gene product from transcript CG6361-RA	0.010
CG12158	CG12158 gene product from transcript CG12158-RA	0.010
CG8216	CG8216 gene product from transcript CG8216-RA	0.010
CG32251	CG32251 gene product from transcript CG32251-RA	0.010
CG15764	CG15764 gene product from transcript CG15764-RA	0.010
Snap24	Synapse protein 24	0.010
Vps45	Vacuolar protein sorting 45	0.010
t	tan	0.010
Pkn	Protein kinase related to protein kinase N	0.010
gce	germ cell-expressed bHLH-PAS	0.010
CG16833	CG16833 gene product from transcript CG16833-RG	0.010
Ant2	Adenine nucleotide translocase 2	0.010
unk	unkempt	0.010
CG3921	CG3921 gene product from transcript CG3921-RA	0.010
Rfx	CG6312 gene product from transcript CG6312-RA	0.010