IMP: Integrative Multi-species Prediction

Drosophila melanogaster

2 genes annotated in fly

autophagic vacuole assembly

The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.

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Known genes in the process in flyInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "autophagic vacuole assembly"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "autophagic vacuole assembly" (in gray)

Name	Description	Probability	Func Analog Organism
Pi3K92E	CG4141 gene product from transcript CG4141-RB	1.000
Atg1	Autophagy-specific gene 1	1.000
Rheb	CG1081 gene product from transcript CG1081-RA	0.998
Akt1	CG4006 gene product from transcript CG4006-RA	0.989
Atg18	Autophagy-specific gene 18	0.989
Pi3K59F	Phosphotidylinositol 3 kinase 59F	0.954	Rat
Pten	CG5671 gene product from transcript CG5671-RB	0.892
gig	gigas	0.836
Atg2	Autophagy-specific gene 2	0.794
Atg8a	Autophagy-specific gene 8a	0.783
Atg4	Autophagy-specific gene 4	0.764	Human Yeast
bsk	basket	0.644
Atg9	Autophagy-specific gene 9	0.638
hep	hemipterous	0.567
Atg7	Autophagy-specific gene 7	0.519
Ras85D	Ras oncogene at 85D	0.460
RagA	CG11968 gene product from transcript CG11968-RA	0.449
dm	diminutive	0.437
Atg6	Autophagy-specific gene 6	0.354
CG11877	CG11877 gene product from transcript CG11877-RA	0.333
rl	rolled	0.304
ird1	immune response deficient 1	0.263
Ide	Insulin degrading metalloproteinase	0.206
CG31033	CG31033 gene product from transcript CG31033-RC	0.184
foxo	forkhead box, sub-group O	0.184
poly	CG9829 gene product from transcript CG9829-RB	0.176
CG8974	CG8974 gene product from transcript CG8974-RD	0.171	Mouse
Tor	Target of rapamycin	0.168
usnp	ubisnap	0.150
Thor	CG8846 gene product from transcript CG8846-RA	0.149
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.146
sav	salvador	0.139
Pka-C1	cAMP-dependent protein kinase 1	0.125
trpml	transient receptor potential mucolipin	0.124
atl	atlastin	0.123
Rab5	Rab-protein 5	0.112
CG7220	CG7220 gene product from transcript CG7220-RD	0.101
Rab7	Rab-protein 7	0.096	Human
key	kenny	0.087
drpr	draper	0.084
S6k	RPS6-p70-protein kinase	0.082	Worm
Syb	Synaptobrevin	0.082
p38b	CG7393 gene product from transcript CG7393-RA	0.079
CG1599	CG1599 gene product from transcript CG1599-RA	0.079
chico	CG5686 gene product from transcript CG5686-RB	0.076
Aut1	CG6877 gene product from transcript CG6877-RA	0.073	Mouse
Atg13	Autophagy-specific gene 13	0.069
Syx17	Syntaxin 17	0.068
vri	vrille	0.066
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.065
Rac2	CG8556 gene product from transcript CG8556-RA	0.065
Rab4	Rab-protein 4	0.064
Pcaf	CG4107 gene product from transcript CG4107-RA	0.063
Vps20	Vacuolar protein sorting 20	0.061
l(2)37Bb	lethal (2) 37Bb	0.061
gbb	glass bottom boat	0.057
pix	pixie	0.055
CG11009	CG11009 gene product from transcript CG11009-RB	0.055
kcc	kazachoc	0.054
hppy	happyhour	0.054
Rab14	Rab-protein 14	0.054
Vps4	Vacuolar protein sorting 4	0.053
krz	kurtz	0.052
Rab-RP4	Rab-related protein 4	0.052
Rab2	Rab-protein 2	0.049
Csp	Cysteine string protein	0.049
WASp	CG1520 gene product from transcript CG1520-RA	0.049
Tom34	Translocase of outer membrane 34	0.048
gammaCop	gamma-coatomer protein	0.047
mts	microtubule star	0.047
Stam	Signal transducing adaptor molecule	0.047
CG6116	CG6116 gene product from transcript CG6116-RA	0.046
TBPH	CG10327 gene product from transcript CG10327-RC	0.046
CG30344	CG30344 gene product from transcript CG30344-RA	0.046
Rfabg	Retinoid- and fatty acid-binding glycoprotein	0.046
Syx5	Syntaxin 5	0.045
ash2	absent, small, or homeotic discs 2	0.045
Klp64D	Kinesin-like protein at 64D	0.045
Wnk	CG7177 gene product from transcript CG7177-RA	0.044
M6	CG7540 gene product from transcript CG7540-RA	0.044
Snap25	Synapse protein 25	0.043
egr	eiger	0.042
ecd	ecdysoneless	0.042
Eip74EF	Ecdysone-induced protein 74EF	0.041
Ilp2	Insulin-like peptide 2	0.041
prel	preli-like	0.040
CG10673	CG10673 gene product from transcript CG10673-RA	0.040
CG8678	CG8678 gene product from transcript CG8678-RA	0.039	Human Fly
CG15309	CG15309 gene product from transcript CG15309-RA	0.039
drd	drop dead	0.039
Snap	Soluble NSF attachment protein	0.038
Ent1	Equilibrative nucleoside transporter 1	0.037
wts	warts	0.036
G-salpha60A	G protein salpha 60A	0.036
capt	capulet	0.035
ninaE	neither inactivation nor afterpotential E	0.034
Hsc70-4	Heat shock protein cognate 4	0.034
Egm	Enigma	0.034
CG15012	CG15012 gene product from transcript CG15012-RB	0.034
bam	bag of marbles	0.033
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.033
CG3004	CG3004 gene product from transcript CG3004-RA	0.032
nero	CG2245 gene product from transcript CG2245-RA	0.031
kuz	kuzbanian	0.031
Tsc1	CG6147 gene product from transcript CG6147-RA	0.031
CdsA	CDP diglyceride synthetase	0.030
Mnt	CG13316 gene product from transcript CG13316-RD	0.030
SNF1A	SNF1A/AMP-activated protein kinase	0.029
Pi3K21B	CG2699 gene product from transcript CG2699-RA	0.029
Ggamma1	G protein gamma 1	0.029
Sh3beta	CG8582 gene product from transcript CG8582-RD	0.029
Arp66B	Actin-related protein 66B	0.029
Jra	Jun-related antigen	0.028
cer	crammer	0.028
Rab11	Rab-protein 11	0.028
Syx7	Syntaxin 7	0.026
vps2	CG14542 gene product from transcript CG14542-RA	0.026
Ilk	Integrin linked kinase	0.026
adp	adipose	0.026
sbb	scribbler	0.026
JhI-1	Juvenile hormone-inducible protein 1	0.026
Rab39	CG12156 gene product from transcript CG12156-RA	0.025
spict	spichthyin	0.025
shrb	shrub	0.025
path	pathetic	0.025
mth	methuselah	0.025
cni	cornichon	0.024
mtm	myotubularin	0.024
CG13603	CG13603 gene product from transcript CG13603-RA	0.024
Hmgs	HMG Coenzyme A synthase	0.023
Arp87C	Actin-related protein 87C	0.023
beta4GalNAcTA	CG8536 gene product from transcript CG8536-RA	0.023
stck	steamer duck	0.022
Yippee	CG1989 gene product from transcript CG1989-RA	0.022
CG3529	CG3529 gene product from transcript CG3529-RB	0.022
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.022
L	Lobe	0.022
Nedd4	CG42279 gene product from transcript CG42279-RJ	0.022
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.022
gammaSnap	gamma-soluble NSF attachment protein	0.021
skpA	CG16983 gene product from transcript CG16983-RD	0.021
aay	astray	0.021
EcR	Ecdysone receptor	0.021
Cdc42	CG12530 gene product from transcript CG12530-RA	0.021
CG3837	CG3837 gene product from transcript CG3837-RA	0.020
amos	absent MD neurons and olfactory sensilla	0.020
Cul-5	Cullin-5	0.020
CG6191	CG6191 gene product from transcript CG6191-RA	0.020
MTF-1	Metal response element-binding Transcription Factor-1	0.020
dsh	dishevelled	0.020
TMS1	CG4672 gene product from transcript CG4672-RA	0.020
wit	wishful thinking	0.020
CG3589	CG3589 gene product from transcript CG3589-RA	0.020
Hph	HIF prolyl hydroxylase	0.019
Snx6	CG8282 gene product from transcript CG8282-RA	0.019
CG14782	CG14782 gene product from transcript CG14782-RA	0.019
Dmn	Dynamitin	0.019
Bx42	CG8264 gene product from transcript CG8264-RA	0.019
Sox14	Sox box protein 14	0.019
Rel	Relish	0.019
l(1)G0193	lethal (1) G0193	0.019
fok	fledgling of Klp38B	0.019
Papss	PAPS synthetase	0.019
lap	like-AP180	0.019
Rpn2	CG11888 gene product from transcript CG11888-RA	0.019
CG7967	CG7967 gene product from transcript CG7967-RA	0.018
coro	CG9446 gene product from transcript CG9446-RC	0.018
Pax	Paxillin	0.018
GckIII	Germinal centre kinase III	0.018
Elp3	Elongator complex protein 3	0.018
por	porcupine	0.018
Ptp61F	Protein tyrosine phosphatase 61F	0.018
Cat	Catalase	0.018
CG8090	CG8090 gene product from transcript CG8090-RB	0.017
Tip60	CG6121 gene product from transcript CG6121-RA	0.017
Mipp2	Multiple inositol polyphosphate phosphatase 2	0.017
CG11534	CG11534 gene product from transcript CG11534-RA	0.017
CG7600	CG7600 gene product from transcript CG7600-RA	0.017
eIF-4a	Eukaryotic initiation factor 4a	0.017
blow	blown fuse	0.017
CG1347	CG1347 gene product from transcript CG1347-RB	0.017
Unc-76	CG3981 gene product from transcript CG3981-RB	0.017
RanBPM	Ran-binding protein M	0.017
Rop	Ras opposite	0.017
unc-13	CG2999 gene product from transcript CG2999-RA	0.017
PRL-1	CG4993 gene product from transcript CG4993-RB	0.017
Mtp	Microsomal triacylglycerol transfer protein	0.016
CG3632	CG3632 gene product from transcript CG3632-RH	0.016
rempA	reduced mechanoreceptor potential A	0.016
scyl	scylla	0.016
endoA	endophilin A	0.016
ImpL2	Ecdysone-inducible gene L2	0.016
lsn	larsen	0.016
CG12007	CG12007 gene product from transcript CG12007-RA	0.015
Glut1	Glucose transporter 1	0.015
Ppt2	Palmitoyl-protein Thioesterase 2	0.015
CSN5	COP9 complex homolog subunit 5	0.015
CG9904	CG9904 gene product from transcript CG9904-RA	0.015
smo	smoothened	0.015
slif	slimfast	0.015
hang	hangover	0.015
yata	CG1973 gene product from transcript CG1973-RA	0.015
Start1	CG3522 gene product from transcript CG3522-RB	0.015
pex16	peroxin 16	0.015
CG7611	CG7611 gene product from transcript CG7611-RJ	0.014
Vps25	Vacuolar protein sorting 25	0.014
Ant2	Adenine nucleotide translocase 2	0.014
CG9139	CG9139 gene product from transcript CG9139-RA	0.014
Rala	Ras-related protein	0.014
Fer1HCH	Ferritin 1 heavy chain homologue	0.014
lqfR	liquid facets-Related	0.014
CG17765	CG17765 gene product from transcript CG17765-RA	0.014
betaggt-I	beta subunit of type I geranylgeranyl transferase	0.014
CG32154	CG32154 gene product from transcript CG32154-RA	0.014
pico	CG11940 gene product from transcript CG11940-RA	0.013
CG32581	CG32581 gene product from transcript CG32581-RB	0.013	Mouse
CG7231	CG7231 gene product from transcript CG7231-RE	0.013
step	steppke	0.013
debcl	death executioner Bcl-2 homologue	0.013
CG7860	CG7860 gene product from transcript CG7860-RA	0.013
wnd	wallenda	0.013
sfl	sulfateless	0.013
CG14184	CG14184 gene product from transcript CG14184-RA	0.013
gatA	glutamyl-tRNA amidotransferase subunit A	0.013
raptor	CG4320 gene product from transcript CG4320-RA	0.013
cutlet	CG33122 gene product from transcript CG33122-RA	0.013
ScpX	Sterol carrier protein X-related thiolase	0.013
Mvl	Malvolio	0.013
Xbp1	X box binding protein-1	0.013
CG7656	CG7656 gene product from transcript CG7656-RA	0.013
bonsai	CG4207 gene product from transcript CG4207-RA	0.013
SamDC	S-adenosylmethionine decarboxylase	0.013
ci	cubitus interruptus	0.013
Dcr-2	Dicer-2	0.012
Syx4	Syntaxin 4	0.012
Hip14	Huntingtin-interacting protein 14	0.012
CG13022	CG13022 gene product from transcript CG13022-RB	0.012
CG6115	CG6115 gene product from transcript CG6115-RA	0.012
Eip71CD	Ecdysone-induced protein 28/29kD	0.012
MED24	Mediator complex subunit 24	0.012
CG6359	CG6359 gene product from transcript CG6359-RA	0.012
sll	slalom	0.012
Pk61C	Protein kinase 61C	0.012
CG4674	CG4674 gene product from transcript CG4674-RA	0.012
Lsd-2	Lipid storage droplet-2	0.012
cpx	complexin	0.012
CG32528	CG32528 gene product from transcript CG32528-RA	0.012
Khc	Kinesin heavy chain	0.012
Atg5	Autophagy-specific gene 5	0.012	Mouse
sra	sarah	0.012
hiw	highwire	0.012
Atg12	Autophagy-specific gene 12	0.012	Yeast
Sas	Sialic acid phosphate synthase	0.011
CG11380	CG11380 gene product from transcript CG11380-RA	0.011
CG10741	CG10741 gene product from transcript CG10741-RB	0.011
Vps16A	Vacuolar protein sorting 16A	0.011
cpa	capping protein alpha	0.011
CG10862	CG10862 gene product from transcript CG10862-RA	0.011
mle	maleless	0.011
CG1902	CG1902 gene product from transcript CG1902-RA	0.011
wun	wunen	0.011
l(3)02640	lethal (3) 02640	0.011
CG30152	CG30152 gene product from transcript CG30152-RA	0.011
Dad	Daughters against dpp	0.011
CG14932	CG14932 gene product from transcript CG14932-RC	0.011
CG4287	CG4287 gene product from transcript CG4287-RB	0.011
sgl	sugarless	0.011
EndoGI	Endonuclease G inhibitor	0.011
CG16721	CG16721 gene product from transcript CG16721-RA	0.011
CG5938	CG5938 gene product from transcript CG5938-RD	0.011
mib1	mind bomb 1	0.011
Irp-1A	Iron regulatory protein 1A	0.011
Nca	Neurocalcin	0.011
GstS1	Glutathione S transferase S1	0.011
CG10103	CG10103 gene product from transcript CG10103-RA	0.011
CG1115	CG1115 gene product from transcript CG1115-RA	0.011
Pli	Pellino	0.011
CG5168	CG5168 gene product from transcript CG5168-RB	0.011
Chmp1	CG4108 gene product from transcript CG4108-RA	0.010
Syt1	Synaptotagmin 1	0.010
CalpA	Calpain-A	0.010
CG8814	CG8814 gene product from transcript CG8814-RA	0.010
stnA	stoned A	0.010
l(2)k09913	lethal (2) k09913	0.010
CG9063	CG9063 gene product from transcript CG9063-RA	0.010
Vps33B	Vacuolar protein sorting 33B	0.010