IMP: Integrative Multi-species Prediction

Homo sapiens

4 genes annotated in human

protein o linked glycosylation via threonine

The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein o linked glycosylation via threonine"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "protein o linked glycosylation via threonine" (in gray)

Name	Description	Probability	Func Analog Organism
SEC23A	Sec23 homolog A (S. cerevisiae)	0.998
GALNT8	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)	0.767
GALNTL1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1	0.716	Human
GALNT9	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)	0.577	Human
GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	0.506	Human
TRAM2	translocation associated membrane protein 2	0.505
GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	0.388
GALNT10	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)	0.367	Human
ARL5A	ADP-ribosylation factor-like 5A	0.301
GALNT13	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)	0.300	Human
FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	0.268
TRAM1	translocation associated membrane protein 1	0.155
GALNTL2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2	0.144	Human
GALNT7	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)	0.125
PIGN	phosphatidylinositol glycan anchor biosynthesis, class N	0.098
GALNT12	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)	0.095
GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)	0.084	Human
MICAL2	microtubule associated monoxygenase, calponin and LIM domain containing 2	0.077
BTBD1	BTB (POZ) domain containing 1	0.076
OR9Q1	olfactory receptor, family 9, subfamily Q, member 1	0.074
GALNT6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)	0.074	Human
POFUT1	protein O-fucosyltransferase 1	0.063
FUT10	fucosyltransferase 10 (alpha (1,3) fucosyltransferase)	0.062
GALNT3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)	0.059
PTPLB	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b	0.058
GALNT11	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)	0.054
LPGAT1	lysophosphatidylglycerol acyltransferase 1	0.053
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.051
KCNG4	potassium voltage-gated channel, subfamily G, member 4	0.050
MAPK6	mitogen-activated protein kinase 6	0.050
FUT4	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)	0.040
MPZL1	myelin protein zero-like 1	0.037
PAPSS1	3'-phosphoadenosine 5'-phosphosulfate synthase 1	0.037
TWSG1	twisted gastrulation homolog 1 (Drosophila)	0.036
SCP2	sterol carrier protein 2	0.035
WDR41	WD repeat domain 41	0.035
TRAPPC8	trafficking protein particle complex 8	0.034
RNF112	ring finger protein 112	0.034
SLC25A47	solute carrier family 25, member 47	0.033
RNF187	ring finger protein 187	0.032
SLC35F1	solute carrier family 35, member F1	0.032
IGLON5	IgLON family member 5	0.029
FUT9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	0.028
STK38L	serine/threonine kinase 38 like	0.028
GNA12	guanine nucleotide binding protein (G protein) alpha 12	0.027
KIAA1409	KIAA1409	0.027
CPXM2	carboxypeptidase X (M14 family), member 2	0.026
MFAP2	microfibrillar-associated protein 2	0.023
PPP4R1	protein phosphatase 4, regulatory subunit 1	0.023
EHD3	EH-domain containing 3	0.022
GSTT1	glutathione S-transferase theta 1	0.021
SSR1	signal sequence receptor, alpha	0.021
RPS4Y1	ribosomal protein S4, Y-linked 1	0.021
RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	0.021
ARHGDIG	Rho GDP dissociation inhibitor (GDI) gamma	0.021
SCN4B	sodium channel, voltage-gated, type IV, beta	0.021
SSFA2	sperm specific antigen 2	0.021
TAF13	TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa	0.020
FAM131A	family with sequence similarity 131, member A	0.020
CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)	0.019
FBXL14	F-box and leucine-rich repeat protein 14	0.019
LRRC4C	leucine rich repeat containing 4C	0.019
SPATA16	spermatogenesis associated 16	0.019
NUCB2	nucleobindin 2	0.019
SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	0.019
ZDHHC7	zinc finger, DHHC-type containing 7	0.019
C20orf3	chromosome 20 open reading frame 3	0.019
LDHC	lactate dehydrogenase C	0.019
KDM5D	lysine (K)-specific demethylase 5D	0.019
FOXK1	forkhead box K1	0.018
C1QTNF2	C1q and tumor necrosis factor related protein 2	0.018
PHACTR2	phosphatase and actin regulator 2	0.017
ZNF155	zinc finger protein 155	0.017
INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	0.017
FUT2	fucosyltransferase 2 (secretor status included)	0.016
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.016
TPST2	tyrosylprotein sulfotransferase 2	0.016
TBX15	T-box 15	0.016
SLC20A2	solute carrier family 20 (phosphate transporter), member 2	0.016
ANXA6	annexin A6	0.016
SLC5A9	solute carrier family 5 (sodium/glucose cotransporter), member 9	0.016
BIK	BCL2-interacting killer (apoptosis-inducing)	0.016
FAM69C	family with sequence similarity 69, member C	0.016
NALCN	sodium leak channel, non-selective	0.015
CNIH3	cornichon homolog 3 (Drosophila)	0.015
NIM1	serine/threonine-protein kinase NIM1	0.015
FAM57A	family with sequence similarity 57, member A	0.015
FNTB	farnesyltransferase, CAAX box, beta	0.015
EHD4	EH-domain containing 4	0.015
PON2	paraoxonase 2	0.015
NXPH1	neurexophilin 1	0.015
PHKA1	phosphorylase kinase, alpha 1 (muscle)	0.015
CTSL2	cathepsin L2	0.015
GOLGA3	golgin A3	0.014
C13orf33	chromosome 13 open reading frame 33	0.014
NAT1	N-acetyltransferase 1 (arylamine N-acetyltransferase)	0.014
ACO1	aconitase 1, soluble	0.014
ERMN	ermin, ERM-like protein	0.014
SPHKAP	SPHK1 interactor, AKAP domain containing	0.014
KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	0.014
DIXDC1	DIX domain containing 1	0.014
DAP	death-associated protein	0.014
GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2	0.014
SLC26A2	solute carrier family 26 (sulfate transporter), member 2	0.014
PISD	phosphatidylserine decarboxylase	0.014
ARHGAP36	Rho GTPase activating protein 36	0.014
TROVE2	TROVE domain family, member 2	0.014
FAM98A	family with sequence similarity 98, member A	0.014
CADM3	cell adhesion molecule 3	0.014
CARD18	caspase recruitment domain family, member 18	0.013
CLMP	CXADR-like membrane protein	0.013
SNRNP35	small nuclear ribonucleoprotein 35kDa (U11/U12)	0.013
QDPR	quinoid dihydropteridine reductase	0.013
FAM131C	family with sequence similarity 131, member C	0.013
KIF3B	kinesin family member 3B	0.013
RGS9BP	regulator of G protein signaling 9 binding protein	0.013
PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H	0.013
C3orf45	chromosome 3 open reading frame 45	0.013
USP26	ubiquitin specific peptidase 26	0.013
RTBDN	retbindin	0.013
MPV17L	MPV17 mitochondrial membrane protein-like	0.013
ELMOD1	ELMO/CED-12 domain containing 1	0.013
GSG1L	GSG1-like	0.013
ENTPD4	ectonucleoside triphosphate diphosphohydrolase 4	0.013
USP9Y	ubiquitin specific peptidase 9, Y-linked	0.013
NRG3	neuregulin 3	0.013
TSPAN5	tetraspanin 5	0.013
SLC22A4	solute carrier family 22 (organic cation/ergothioneine transporter), member 4	0.013
CRISP3	cysteine-rich secretory protein 3	0.013
ABCB4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	0.013
EGFLAM	EGF-like, fibronectin type III and laminin G domains	0.013
SLC39A14	solute carrier family 39 (zinc transporter), member 14	0.013
HSD17B12	hydroxysteroid (17-beta) dehydrogenase 12	0.013
EPHX4	epoxide hydrolase 4	0.012
GALNTL5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5	0.012	Human
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.012
NRGN	neurogranin (protein kinase C substrate, RC3)	0.012
FAM118A	family with sequence similarity 118, member A	0.012
CNNM4	cyclin M4	0.012
KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3	0.012
WDR91	WD repeat domain 91	0.012
CNTN3	contactin 3 (plasmacytoma associated)	0.012
C3orf52	chromosome 3 open reading frame 52	0.012
FRK	fyn-related kinase	0.012
CCDC85A	coiled-coil domain containing 85A	0.012
PNMAL1	PNMA-like 1	0.012
LEPRE1	leucine proline-enriched proteoglycan (leprecan) 1	0.012
SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6	0.012
PRKX	protein kinase, X-linked	0.012
TYRO3	TYRO3 protein tyrosine kinase	0.012
KTN1	kinectin 1 (kinesin receptor)	0.012
C9orf91	chromosome 9 open reading frame 91	0.012
FAR2	fatty acyl CoA reductase 2	0.012
GPR158	G protein-coupled receptor 158	0.012
KPTN	kaptin (actin binding protein)	0.012
TSPYL5	TSPY-like 5	0.012
RAP1GAP2	RAP1 GTPase activating protein 2	0.012
MATN3	matrilin 3	0.012
PANX1	pannexin 1	0.012
PPP1R14C	protein phosphatase 1, regulatory (inhibitor) subunit 14C	0.012
RNF150	ring finger protein 150	0.012
KBTBD11	kelch repeat and BTB (POZ) domain containing 11	0.012
GNA14	guanine nucleotide binding protein (G protein), alpha 14	0.012
ELOVL4	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4	0.012
ZNF165	zinc finger protein 165	0.012
MPPE1	metallophosphoesterase 1	0.012
COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)	0.012
FEZ2	fasciculation and elongation protein zeta 2 (zygin II)	0.012
FSTL5	follistatin-like 5	0.012
BEND5	BEN domain containing 5	0.012
PPAPDC1A	phosphatidic acid phosphatase type 2 domain containing 1A	0.012
CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3	0.012
TSPAN13	tetraspanin 13	0.012
SRD5A3	steroid 5 alpha-reductase 3	0.012
SUSD5	sushi domain containing 5	0.012
CPPED1	calcineurin-like phosphoesterase domain containing 1	0.011
PGD	phosphogluconate dehydrogenase	0.011
FSIP1	fibrous sheath interacting protein 1	0.011
KIAA1239	KIAA1239	0.011
ALDOC	aldolase C, fructose-bisphosphate	0.011
O3FAR1	omega-3 fatty acid receptor 1	0.011
SULT1C4	sulfotransferase family, cytosolic, 1C, member 4	0.011
POPDC3	popeye domain containing 3	0.011
TM7SF3	transmembrane 7 superfamily member 3	0.011
C1orf216	chromosome 1 open reading frame 216	0.011
ABCG2	ATP-binding cassette, sub-family G (WHITE), member 2	0.011
MSTN	myostatin	0.011
C1orf198	chromosome 1 open reading frame 198	0.011
PLAC9	placenta-specific 9	0.011
NRK	Nik related kinase	0.011
VAT1L	vesicle amine transport protein 1 homolog (T. californica)-like	0.011
PPCDC	phosphopantothenoylcysteine decarboxylase	0.011
UNC13B	unc-13 homolog B (C. elegans)	0.011
C4orf7	chromosome 4 open reading frame 7	0.011
TMEM27	transmembrane protein 27	0.011
DDAH1	dimethylarginine dimethylaminohydrolase 1	0.011
ACRC	acidic repeat containing	0.011
EBLN2	endogenous Borna-like N element-2	0.011
CCBE1	collagen and calcium binding EGF domains 1	0.011
ARPM1	actin related protein M1	0.011
ZNF643	zinc finger protein 643	0.011
OLFM4	olfactomedin 4	0.011
TEX2	testis expressed 2	0.011
C18orf8	chromosome 18 open reading frame 8	0.011
HOXB2	homeobox B2	0.011
KIAA0317	KIAA0317	0.011
FKBP1B	FK506 binding protein 1B, 12.6 kDa	0.011
NXN	nucleoredoxin	0.010
ACY3	aspartoacylase (aminocyclase) 3	0.010
FAM110B	family with sequence similarity 110, member B	0.010
CCDC109A	coiled-coil domain containing 109A	0.010
C11orf75	chromosome 11 open reading frame 75	0.010
OR4S2	olfactory receptor, family 4, subfamily S, member 2	0.010
ARF4	ADP-ribosylation factor 4	0.010
POMZP3	POM121 and ZP3 fusion	0.010
ADCY5	adenylate cyclase 5	0.010
TMEM117	transmembrane protein 117	0.010
TMEM22	transmembrane protein 22	0.010
ZNF516	zinc finger protein 516	0.010
SYT4	synaptotagmin IV	0.010
RAB7L1	RAB7, member RAS oncogene family-like 1	0.010
LEPREL4	leprecan-like 4	0.010
OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)	0.010
ZNF582	zinc finger protein 582	0.010
DUSP14	dual specificity phosphatase 14	0.010
DNER	delta/notch-like EGF repeat containing	0.010
ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H	0.010
CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2	0.010
MFHAS1	malignant fibrous histiocytoma amplified sequence 1	0.010
DDX19B	DEAD (Asp-Glu-Ala-As) box polypeptide 19B	0.010
NBAS	neuroblastoma amplified sequence	0.010
PDLIM1	PDZ and LIM domain 1	0.010
TMEM17	transmembrane protein 17	0.010