IMP: Integrative Multi-species Prediction

Homo sapiens

1 genes annotated in human

positive regulation of glucocorticoid biosynthetic process

GO:0031948

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of glucocorticoid biosynthetic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of glucocorticoid biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
FGF18	fibroblast growth factor 18	0.976
WNT1	wingless-type MMTV integration site family, member 1	0.944	Human
WIF1	WNT inhibitory factor 1	0.859
WNT10A	wingless-type MMTV integration site family, member 10A	0.722	Human
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.531
IHH	Indian hedgehog	0.474
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.397
WNT3	wingless-type MMTV integration site family, member 3	0.372	Human
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.317
TLX3	T-cell leukemia homeobox 3	0.281
HES2	hairy and enhancer of split 2 (Drosophila)	0.270
FGF3	fibroblast growth factor 3	0.259
LBX1	ladybird homeobox 1	0.249
WNT4	wingless-type MMTV integration site family, member 4	0.243
FGF4	fibroblast growth factor 4	0.227
P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	0.192
SFRP1	secreted frizzled-related protein 1	0.180
FGF8	fibroblast growth factor 8 (androgen-induced)	0.178
SOX21	SRY (sex determining region Y)-box 21	0.166
CRLF1	cytokine receptor-like factor 1	0.159
DLX4	distal-less homeobox 4	0.150
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.148
FOXF2	forkhead box F2	0.126
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.117
FOXL1	forkhead box L1	0.115
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.111
PRRX2	paired related homeobox 2	0.105
SHH	sonic hedgehog	0.103
AQP5	aquaporin 5	0.098
WNT11	wingless-type MMTV integration site family, member 11	0.096	Human
HMX1	H6 family homeobox 1	0.091
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.087
WNT9B	wingless-type MMTV integration site family, member 9B	0.086	Human
HOXA11	homeobox A11	0.083
CDX2	caudal type homeobox 2	0.080
HOXD13	homeobox D13	0.076
FOXD3	forkhead box D3	0.074
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.072
WNT7A	wingless-type MMTV integration site family, member 7A	0.072	Human
KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	0.071
CDX1	caudal type homeobox 1	0.069
SOX1	SRY (sex determining region Y)-box 1	0.067
GUCA2A	guanylate cyclase activator 2A (guanylin)	0.066
WNT10B	wingless-type MMTV integration site family, member 10B	0.065	Human
GDNF	glial cell derived neurotrophic factor	0.065
HOXC8	homeobox C8	0.063
BHLHE23	basic helix-loop-helix family, member e23	0.063
WNT6	wingless-type MMTV integration site family, member 6	0.063	Human
NKD2	naked cuticle homolog 2 (Drosophila)	0.058
LMX1A	LIM homeobox transcription factor 1, alpha	0.058
NTN1	netrin 1	0.058
SFRP5	secreted frizzled-related protein 5	0.055
ESPN	espin	0.055
PITX3	paired-like homeodomain 3	0.054
BMP4	bone morphogenetic protein 4	0.054
NKD1	naked cuticle homolog 1 (Drosophila)	0.053
FIBCD1	fibrinogen C domain containing 1	0.051
RAX	retina and anterior neural fold homeobox	0.051
PAX8	paired box 8	0.051
GGN	gametogenetin	0.050
FZD8	frizzled homolog 8 (Drosophila)	0.047
ADRB3	adrenergic, beta-3-, receptor	0.046
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.044
HOXD11	homeobox D11	0.044
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.043
OVOL1	ovo-like 1(Drosophila)	0.043
PITX1	paired-like homeodomain 1	0.041
KREMEN2	kringle containing transmembrane protein 2	0.041
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.041
USH1G	Usher syndrome 1G (autosomal recessive)	0.040
BMP8A	bone morphogenetic protein 8a	0.040
KCNK9	potassium channel, subfamily K, member 9	0.039
PRPH	peripherin	0.039
BEST2	bestrophin 2	0.038
EXOC3L2	exocyst complex component 3-like 2	0.038
SIX2	SIX homeobox 2	0.036
GSX2	GS homeobox 2	0.035
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.035
NKX3-2	NK3 homeobox 2	0.035
BARHL1	BarH-like homeobox 1	0.035
PAX3	paired box 3	0.034
COL2A1	collagen, type II, alpha 1	0.033
NPAS1	neuronal PAS domain protein 1	0.033
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.033
EVPL	envoplakin	0.033
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.033
HES5	hairy and enhancer of split 5 (Drosophila)	0.032
ADRA1D	adrenergic, alpha-1D-, receptor	0.032
HOXB8	homeobox B8	0.032
C1QL1	complement component 1, q subcomponent-like 1	0.032
MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	0.031
DUOX1	dual oxidase 1	0.030
GSC	goosecoid homeobox	0.030
FGF19	fibroblast growth factor 19	0.030
SLC30A2	solute carrier family 30 (zinc transporter), member 2	0.030
ACAN	aggrecan	0.030
POU3F1	POU class 3 homeobox 1	0.029
MNX1	motor neuron and pancreas homeobox 1	0.029
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.029
RHBG	Rh family, B glycoprotein (gene/pseudogene)	0.029
GRIK3	glutamate receptor, ionotropic, kainate 3	0.029
ALX4	ALX homeobox 4	0.028
POU4F3	POU class 4 homeobox 3	0.028
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.028
PITX2	paired-like homeodomain 2	0.028
COL4A6	collagen, type IV, alpha 6	0.028
HOXB1	homeobox B1	0.027
OTP	orthopedia homeobox	0.027
NKPD1	NTPase, KAP family P-loop domain containing 1	0.026
HOXC12	homeobox C12	0.026
AVPR1B	arginine vasopressin receptor 1B	0.026
SYT12	synaptotagmin XII	0.026
EPHB2	EPH receptor B2	0.026
VSX1	visual system homeobox 1	0.025
HOXD9	homeobox D9	0.025
SCARF2	scavenger receptor class F, member 2	0.025
NEUROD2	neurogenic differentiation 2	0.024
ADAMTSL2	ADAMTS-like 2	0.024
NXNL2	nucleoredoxin-like 2	0.024
LAMA1	laminin, alpha 1	0.024
FAM43B	family with sequence similarity 43, member B	0.024
KLF14	Kruppel-like factor 14	0.023
VSTM2L	V-set and transmembrane domain containing 2 like	0.023
DHH	desert hedgehog	0.023
TBX1	T-box 1	0.023
SCUBE1	signal peptide, CUB domain, EGF-like 1	0.023
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.023
RGS9BP	regulator of G protein signaling 9 binding protein	0.023
NPPC	natriuretic peptide C	0.023
IRX4	iroquois homeobox 4	0.023
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.022
VEGFC	vascular endothelial growth factor C	0.022
CHRD	chordin	0.022
OPRD1	opioid receptor, delta 1	0.022
PLXDC1	plexin domain containing 1	0.022
RASL10A	RAS-like, family 10, member A	0.022
HOXD4	homeobox D4	0.022
HOXD10	homeobox D10	0.021
EN1	engrailed homeobox 1	0.021
FOXN4	forkhead box N4	0.021
EFNA3	ephrin-A3	0.021
FEZF2	FEZ family zinc finger 2	0.021
SYT8	synaptotagmin VIII	0.021
FZD10	frizzled homolog 10 (Drosophila)	0.021
SLC29A4	solute carrier family 29 (nucleoside transporters), member 4	0.020
ACTRT2	actin-related protein T2	0.020
DLL4	delta-like 4 (Drosophila)	0.020
SMTNL2	smoothelin-like 2	0.020
NEUROG2	neurogenin 2	0.020
RTBDN	retbindin	0.020
TLX2	T-cell leukemia homeobox 2	0.019
NKX2-1	NK2 homeobox 1	0.019
TNK1	tyrosine kinase, non-receptor, 1	0.019
INSL3	insulin-like 3 (Leydig cell)	0.019
LMO1	LIM domain only 1 (rhombotin 1)	0.019
OLIG2	oligodendrocyte lineage transcription factor 2	0.019
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.019
COL13A1	collagen, type XIII, alpha 1	0.019
POU3F3	POU class 3 homeobox 3	0.018
ALOX12B	arachidonate 12-lipoxygenase, 12R type	0.018
HOXC6	homeobox C6	0.018
CSDC2	cold shock domain containing C2, RNA binding	0.018
PAX1	paired box 1	0.018
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.018
DRD4	dopamine receptor D4	0.018
HES7	hairy and enhancer of split 7 (Drosophila)	0.018
DLX3	distal-less homeobox 3	0.018
HOXB13	homeobox B13	0.018
ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.018
BNC1	basonuclin 1	0.017
ADAMTSL5	ADAMTS-like 5	0.017
CRABP2	cellular retinoic acid binding protein 2	0.017
CDHR1	cadherin-related family member 1	0.017
BFSP1	beaded filament structural protein 1, filensin	0.017
GSC2	goosecoid homeobox 2	0.017
ICOSLG	inducible T-cell co-stimulator ligand	0.017
TACR1	tachykinin receptor 1	0.017
HOXD1	homeobox D1	0.017
PNOC	prepronociceptin	0.017
FOXL2	forkhead box L2	0.017
NPFFR1	neuropeptide FF receptor 1	0.017
NKX6-2	NK6 homeobox 2	0.016
NXNL1	nucleoredoxin-like 1	0.016
EMX2	empty spiracles homeobox 2	0.016
NOTUM	notum pectinacetylesterase homolog (Drosophila)	0.016
MIXL1	Mix1 homeobox-like 1 (Xenopus laevis)	0.016
FOXF1	forkhead box F1	0.016
CD70	CD70 molecule	0.016
CARD10	caspase recruitment domain family, member 10	0.016
WNT2B	wingless-type MMTV integration site family, member 2B	0.016	Human
PSAPL1	prosaposin-like 1 (gene/pseudogene)	0.016
UTF1	undifferentiated embryonic cell transcription factor 1	0.016
KNDC1	kinase non-catalytic C-lobe domain (KIND) containing 1	0.016
PAX7	paired box 7	0.015
MESP1	mesoderm posterior 1 homolog (mouse)	0.015
CST1	cystatin SN	0.015
TBX5	T-box 5	0.015
TTC22	tetratricopeptide repeat domain 22	0.015
CXCL14	chemokine (C-X-C motif) ligand 14	0.015
HOXC5	homeobox C5	0.015
DLX5	distal-less homeobox 5	0.015
WNT2	wingless-type MMTV integration site family member 2	0.015	Human
TMEM151A	transmembrane protein 151A	0.015
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.015
HOXD3	homeobox D3	0.015
B4GALNT2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.015
CDH22	cadherin 22, type 2	0.014
FGD1	FYVE, RhoGEF and PH domain containing 1	0.014
STAC2	SH3 and cysteine rich domain 2	0.014
ALOX12	arachidonate 12-lipoxygenase	0.014
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.014
NLRP6	NLR family, pyrin domain containing 6	0.014
ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif, 7	0.014
NKX2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.014
NGF	nerve growth factor (beta polypeptide)	0.014
KLC3	kinesin light chain 3	0.014
CEL	carboxyl ester lipase (bile salt-stimulated lipase)	0.014
COL4A4	collagen, type IV, alpha 4	0.014
GSX1	GS homeobox 1	0.014
ADAMTS17	ADAM metallopeptidase with thrombospondin type 1 motif, 17	0.014
KCNK12	potassium channel, subfamily K, member 12	0.014
GJA3	gap junction protein, alpha 3, 46kDa	0.014
CTF1	cardiotrophin 1	0.013
GUCY1A2	guanylate cyclase 1, soluble, alpha 2	0.013
HR	hairless homolog (mouse)	0.013
KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	0.013
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.013
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.013
CPNE9	copine family member IX	0.013
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	0.013
ODF3L1	outer dense fiber of sperm tails 3-like 1	0.013
PRDM16	PR domain containing 16	0.013
INSM2	insulinoma-associated 2	0.013
TKTL1	transketolase-like 1	0.013
HYAL1	hyaluronoglucosaminidase 1	0.013
OCA2	oculocutaneous albinism II	0.013
NOXO1	NADPH oxidase organizer 1	0.013
GLDC	glycine dehydrogenase (decarboxylating)	0.013
B3GNT3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	0.013
PYY	peptide YY	0.013
FGF10	fibroblast growth factor 10	0.013
SIM2	single-minded homolog 2 (Drosophila)	0.013
PRDM13	PR domain containing 13	0.013
FAM101A	family with sequence similarity 101, member A	0.013
EID3	EP300 interacting inhibitor of differentiation 3	0.013
SLC38A3	solute carrier family 38, member 3	0.013
GPR20	G protein-coupled receptor 20	0.013
PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3	0.012
CCBE1	collagen and calcium binding EGF domains 1	0.012
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.012
EMX1	empty spiracles homeobox 1	0.012
SIX3	SIX homeobox 3	0.012
GATA5	GATA binding protein 5	0.012
LHX6	LIM homeobox 6	0.012
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.012
RHOD	ras homolog gene family, member D	0.012
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.012
GSTT1	glutathione S-transferase theta 1	0.012
ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2	0.012
FAM163A	family with sequence similarity 163, member A	0.012
HCRTR1	hypocretin (orexin) receptor 1	0.012
HIC1	hypermethylated in cancer 1	0.012
CRTAC1	cartilage acidic protein 1	0.012
CCNO	cyclin O	0.012
NXPH3	neurexophilin 3	0.012
COL9A3	collagen, type IX, alpha 3	0.012
RTN4R	reticulon 4 receptor	0.012
IRF2BP1	interferon regulatory factor 2 binding protein 1	0.012
HOXB9	homeobox B9	0.012
LBP	lipopolysaccharide binding protein	0.012
ROM1	retinal outer segment membrane protein 1	0.012
GJB5	gap junction protein, beta 5, 31.1kDa	0.012
NPM2	nucleophosmin/nucleoplasmin 2	0.012
KCNK17	potassium channel, subfamily K, member 17	0.012
GJD3	gap junction protein, delta 3, 31.9kDa	0.012
PVRL4	poliovirus receptor-related 4	0.012
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.012
GLI2	GLI family zinc finger 2	0.012
CACNG4	calcium channel, voltage-dependent, gamma subunit 4	0.012
OSR1	odd-skipped related 1 (Drosophila)	0.012
KRT14	keratin 14	0.012
HMX2	H6 family homeobox 2	0.012
EPHB6	EPH receptor B6	0.011
NPAS4	neuronal PAS domain protein 4	0.011
ADRA1B	adrenergic, alpha-1B-, receptor	0.011
IRX5	iroquois homeobox 5	0.011
LYPD3	LY6/PLAUR domain containing 3	0.011
DMRT3	doublesex and mab-3 related transcription factor 3	0.011
PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.011
APCDD1L	adenomatosis polyposis coli down-regulated 1-like	0.011
PALM	paralemmin	0.011
EPHA8	EPH receptor A8	0.011
VGLL2	vestigial like 2 (Drosophila)	0.011
REG1B	regenerating islet-derived 1 beta	0.011
CORIN	corin, serine peptidase	0.011
GDF10	growth differentiation factor 10	0.011
FAM163B	family with sequence similarity 163, member B	0.011
DAPK2	death-associated protein kinase 2	0.011
TBX3	T-box 3	0.011
ONECUT2	one cut homeobox 2	0.011
PIP5KL1	phosphatidylinositol-4-phosphate 5-kinase-like 1	0.011
PI16	peptidase inhibitor 16	0.011
ARSI	arylsulfatase family, member I	0.011
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.011
RSPO1	R-spondin homolog (Xenopus laevis)	0.011
ATOH8	atonal homolog 8 (Drosophila)	0.011
C2CD4C	C2 calcium-dependent domain containing 4C	0.011
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.011
SHOX2	short stature homeobox 2	0.011
SFRP4	secreted frizzled-related protein 4	0.011
PF4	platelet factor 4	0.011
KRTDAP	keratinocyte differentiation-associated protein	0.011
TLL2	tolloid-like 2	0.011
CDKL1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.011
MMP19	matrix metallopeptidase 19	0.011
KCNK7	potassium channel, subfamily K, member 7	0.011
SMO	smoothened homolog (Drosophila)	0.011
BHMT	betaine--homocysteine S-methyltransferase	0.011
ASCL2	achaete-scute complex homolog 2 (Drosophila)	0.011
GYLTL1B	glycosyltransferase-like 1B	0.011
TCF21	transcription factor 21	0.011
INHBB	inhibin, beta B	0.011
NTF4	neurotrophin 4	0.010
S100A3	S100 calcium binding protein A3	0.010
GABRE	gamma-aminobutyric acid (GABA) A receptor, epsilon	0.010
SLC5A5	solute carrier family 5 (sodium iodide symporter), member 5	0.010
SP5	Sp5 transcription factor	0.010
GALR3	galanin receptor 3	0.010
COL19A1	collagen, type XIX, alpha 1	0.010
TBX2	T-box 2	0.010
SLMO1	slowmo homolog 1 (Drosophila)	0.010
RPRML	reprimo-like	0.010
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	0.010
IL17C	interleukin 17C	0.010
KLHL35	kelch-like 35 (Drosophila)	0.010
WT1	Wilms tumor 1	0.010
EYA2	eyes absent homolog 2 (Drosophila)	0.010
PCSK9	proprotein convertase subtilisin/kexin type 9	0.010
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.010
FBXL22	F-box and leucine-rich repeat protein 22	0.010