IMP: Integrative Multi-species Prediction

Homo sapiens

1 genes annotated in human

cloacal septation

The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cloacal septation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cloacal septation" (in gray)

Name	Description	Probability	Func Analog Organism
KRT5	keratin 5	1.000
CABLES1	Cdk5 and Abl enzyme substrate 1	0.982
SATB2	SATB homeobox 2	0.967
FGF18	fibroblast growth factor 18	0.911
KRT6C	keratin 6C	0.819
ZFYVE9	zinc finger, FYVE domain containing 9	0.812
WNT1	wingless-type MMTV integration site family, member 1	0.407	Human
S1PR5	sphingosine-1-phosphate receptor 5	0.377
WIF1	WNT inhibitory factor 1	0.343
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.219
HNRNPCL1	heterogeneous nuclear ribonucleoprotein C-like 1	0.198
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.192
TNK1	tyrosine kinase, non-receptor, 1	0.185
SFRP1	secreted frizzled-related protein 1	0.157
NPAS1	neuronal PAS domain protein 1	0.135
IHH	Indian hedgehog	0.130
WNT3	wingless-type MMTV integration site family, member 3	0.119	Human
WNT10A	wingless-type MMTV integration site family, member 10A	0.113	Human
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.104
POU3F1	POU class 3 homeobox 1	0.093
FGF3	fibroblast growth factor 3	0.090
NIPSNAP3A	nipsnap homolog 3A (C. elegans)	0.084
HPX	hemopexin	0.068
BMPR1A	bone morphogenetic protein receptor, type IA	0.065
GUCA2A	guanylate cyclase activator 2A (guanylin)	0.060
BMP8A	bone morphogenetic protein 8a	0.060
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.059
HES2	hairy and enhancer of split 2 (Drosophila)	0.058
WNT4	wingless-type MMTV integration site family, member 4	0.055	Human
LY6D	lymphocyte antigen 6 complex, locus D	0.055
UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	0.055
DAPK2	death-associated protein kinase 2	0.054
BMP2	bone morphogenetic protein 2	0.053
FGF4	fibroblast growth factor 4	0.052
FOXF2	forkhead box F2	0.052
ZNF676	zinc finger protein 676	0.048
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.048
SHH	sonic hedgehog	0.047
BMP4	bone morphogenetic protein 4	0.047	Mouse
HMX1	H6 family homeobox 1	0.046
WNT11	wingless-type MMTV integration site family, member 11	0.042
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.042
COL4A6	collagen, type IV, alpha 6	0.042
PAX8	paired box 8	0.041
AQP5	aquaporin 5	0.040
KRT6A	keratin 6A	0.040
FZD10	frizzled homolog 10 (Drosophila)	0.039
LBX1	ladybird homeobox 1	0.039
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.038
FSTL1	follistatin-like 1	0.038
HOXA11	homeobox A11	0.037
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.037
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.036
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.036
TLX3	T-cell leukemia homeobox 3	0.034
NKD1	naked cuticle homolog 1 (Drosophila)	0.034
EPHB2	EPH receptor B2	0.034
P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	0.033
PAX3	paired box 3	0.033
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.033
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.033
NKD2	naked cuticle homolog 2 (Drosophila)	0.033
NEUROG2	neurogenin 2	0.032
WNT7A	wingless-type MMTV integration site family, member 7A	0.032	Human
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.031
HOXD13	homeobox D13	0.031
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.031
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.030
LHX6	LIM homeobox 6	0.030
LMX1A	LIM homeobox transcription factor 1, alpha	0.030
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.030
SLC29A4	solute carrier family 29 (nucleoside transporters), member 4	0.030
BNC1	basonuclin 1	0.030
SOX21	SRY (sex determining region Y)-box 21	0.030
HOXC8	homeobox C8	0.029
LYPD3	LY6/PLAUR domain containing 3	0.029
FGD1	FYVE, RhoGEF and PH domain containing 1	0.028
ACAN	aggrecan	0.028
EFNA3	ephrin-A3	0.027
GSTM4	glutathione S-transferase mu 4	0.027
GDNF	glial cell derived neurotrophic factor	0.026
HOXD10	homeobox D10	0.026
CRLF1	cytokine receptor-like factor 1	0.025
CTF1	cardiotrophin 1	0.025
WNT10B	wingless-type MMTV integration site family, member 10B	0.025	Human
EPHB3	EPH receptor B3	0.024
PRRX2	paired related homeobox 2	0.024
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.023
HOXB13	homeobox B13	0.023
BMP7	bone morphogenetic protein 7	0.023
SMO	smoothened homolog (Drosophila)	0.023
PRSS53	protease, serine, 53	0.022
DUOX1	dual oxidase 1	0.022
IRX4	iroquois homeobox 4	0.022
GPR3	G protein-coupled receptor 3	0.022
EVPL	envoplakin	0.022
EXOC3L2	exocyst complex component 3-like 2	0.022
WNT7B	wingless-type MMTV integration site family, member 7B	0.021	Human
HOXD11	homeobox D11	0.021
SIX2	SIX homeobox 2	0.021
SHROOM1	shroom family member 1	0.021
ARTN	artemin	0.021
GLI3	GLI family zinc finger 3	0.021
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.021
RSPO1	R-spondin homolog (Xenopus laevis)	0.021
CA9	carbonic anhydrase IX	0.021
ENDOU	endonuclease, polyU-specific	0.021
PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3	0.021
CARD10	caspase recruitment domain family, member 10	0.021
MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	0.021
KLHL35	kelch-like 35 (Drosophila)	0.020
CXCL14	chemokine (C-X-C motif) ligand 14	0.020
BMP6	bone morphogenetic protein 6	0.020
PITX1	paired-like homeodomain 1	0.020
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.020
CDHR1	cadherin-related family member 1	0.020
FST	follistatin	0.020
HIST1H1D	histone cluster 1, H1d	0.020
RCOR2	REST corepressor 2	0.019
NOTCH3	notch 3	0.019
FGF19	fibroblast growth factor 19	0.019
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.019
TCF21	transcription factor 21	0.019
FGF22	fibroblast growth factor 22	0.019
KRT4	keratin 4	0.019
FIBCD1	fibrinogen C domain containing 1	0.019
WNT2B	wingless-type MMTV integration site family, member 2B	0.019	Human
MNX1	motor neuron and pancreas homeobox 1	0.019
NXPH4	neurexophilin 4	0.019
CCDC48	coiled-coil domain containing 48	0.019
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.018
FZD8	frizzled homolog 8 (Drosophila)	0.018
COL2A1	collagen, type II, alpha 1	0.018
CDX1	caudal type homeobox 1	0.018
FUS	fused in sarcoma	0.018
DLX4	distal-less homeobox 4	0.018
HOXC12	homeobox C12	0.018
HYAL1	hyaluronoglucosaminidase 1	0.018
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.018
NKX3-2	NK3 homeobox 2	0.018
VSTM2L	V-set and transmembrane domain containing 2 like	0.018
TCERG1L	transcription elongation regulator 1-like	0.018
TNFSF9	tumor necrosis factor (ligand) superfamily, member 9	0.018
LTK	leukocyte receptor tyrosine kinase	0.018
DLK1	delta-like 1 homolog (Drosophila)	0.018
HOXC6	homeobox C6	0.017
WNT6	wingless-type MMTV integration site family, member 6	0.017	Human
KCNK9	potassium channel, subfamily K, member 9	0.017
PRSS16	protease, serine, 16 (thymus)	0.017
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.017
ADRA1A	adrenergic, alpha-1A-, receptor	0.017
CDX2	caudal type homeobox 2	0.017
RARG	retinoic acid receptor, gamma	0.017
PLXDC1	plexin domain containing 1	0.017
INSM2	insulinoma-associated 2	0.017
DSG3	desmoglein 3	0.017
HOXB8	homeobox B8	0.017
PITX2	paired-like homeodomain 2	0.017
KLK7	kallikrein-related peptidase 7	0.016
GPR20	G protein-coupled receptor 20	0.016
ADAMTS16	ADAM metallopeptidase with thrombospondin type 1 motif, 16	0.016
GDF10	growth differentiation factor 10	0.016
ZACN	zinc activated ligand-gated ion channel	0.016
CAMK4	calcium/calmodulin-dependent protein kinase IV	0.016
GAS1	growth arrest-specific 1	0.016
EN1	engrailed homeobox 1	0.016
HR	hairless homolog (mouse)	0.016
ODF3L1	outer dense fiber of sperm tails 3-like 1	0.016
CD70	CD70 molecule	0.016
GPR153	G protein-coupled receptor 153	0.016
ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)	0.016
FAT2	FAT tumor suppressor homolog 2 (Drosophila)	0.016
SMTNL2	smoothelin-like 2	0.016
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.016
CD248	CD248 molecule, endosialin	0.016
SAMD11	sterile alpha motif domain containing 11	0.016
GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	0.015
GSTT1	glutathione S-transferase theta 1	0.015
HES5	hairy and enhancer of split 5 (Drosophila)	0.015
ROR1	receptor tyrosine kinase-like orphan receptor 1	0.015
GGN	gametogenetin	0.015
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.015
TAF15	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	0.015
STAC2	SH3 and cysteine rich domain 2	0.015
PALM	paralemmin	0.015
KLK10	kallikrein-related peptidase 10	0.015
VIPR2	vasoactive intestinal peptide receptor 2	0.015
DLX3	distal-less homeobox 3	0.015
PTHLH	parathyroid hormone-like hormone	0.015
RGS9BP	regulator of G protein signaling 9 binding protein	0.015
MMP19	matrix metallopeptidase 19	0.014
PPFIA3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	0.014
SUMF2	sulfatase modifying factor 2	0.014
BAIAP3	BAI1-associated protein 3	0.014
FAM163A	family with sequence similarity 163, member A	0.014
PRKG1	protein kinase, cGMP-dependent, type I	0.014
KLC3	kinesin light chain 3	0.014
CST1	cystatin SN	0.014
KCNK13	potassium channel, subfamily K, member 13	0.014
IL17C	interleukin 17C	0.014
OLIG2	oligodendrocyte lineage transcription factor 2	0.014
SOD3	superoxide dismutase 3, extracellular	0.014
HOXC5	homeobox C5	0.014
SLC30A2	solute carrier family 30 (zinc transporter), member 2	0.014
CLCA2	chloride channel accessory 2	0.014
OTP	orthopedia homeobox	0.014
ANO1	anoctamin 1, calcium activated chloride channel	0.014
FOXB1	forkhead box B1	0.014
ADAMTSL5	ADAMTS-like 5	0.013
FOXL2	forkhead box L2	0.013
COL10A1	collagen, type X, alpha 1	0.013
EFNA5	ephrin-A5	0.013
C1QTNF2	C1q and tumor necrosis factor related protein 2	0.013
OCA2	oculocutaneous albinism II	0.013
SOSTDC1	sclerostin domain containing 1	0.013
WT1	Wilms tumor 1	0.013
BFSP1	beaded filament structural protein 1, filensin	0.013
PI16	peptidase inhibitor 16	0.013
CNTFR	ciliary neurotrophic factor receptor	0.013
LPAR3	lysophosphatidic acid receptor 3	0.013
COL17A1	collagen, type XVII, alpha 1	0.013
KRTDAP	keratinocyte differentiation-associated protein	0.013
UPK2	uroplakin 2	0.013
PLCH2	phospholipase C, eta 2	0.013
PF4	platelet factor 4	0.013
KAZALD1	Kazal-type serine peptidase inhibitor domain 1	0.013
SOCS7	suppressor of cytokine signaling 7	0.013
GABRE	gamma-aminobutyric acid (GABA) A receptor, epsilon	0.013
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.013
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.013
WNT5B	wingless-type MMTV integration site family, member 5B	0.013	Human
GRASP	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein	0.013
SLC22A12	solute carrier family 22 (organic anion/urate transporter), member 12	0.013
TGFB3	transforming growth factor, beta 3	0.013
PRPH	peripherin	0.013
CPNE9	copine family member IX	0.013
TBX3	T-box 3	0.012
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.012
KNDC1	kinase non-catalytic C-lobe domain (KIND) containing 1	0.012
ONECUT2	one cut homeobox 2	0.012
ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2	0.012
HMX2	H6 family homeobox 2	0.012
DLX2	distal-less homeobox 2	0.012
FAM101A	family with sequence similarity 101, member A	0.012
ALOX15B	arachidonate 15-lipoxygenase, type B	0.012
GRIK3	glutamate receptor, ionotropic, kainate 3	0.012
SP5	Sp5 transcription factor	0.012
CCBE1	collagen and calcium binding EGF domains 1	0.012
B4GALNT3	beta-1,4-N-acetyl-galactosaminyl transferase 3	0.012
FRMPD4	FERM and PDZ domain containing 4	0.012
SRRM4	serine/arginine repetitive matrix 4	0.012
DNAJC22	DnaJ (Hsp40) homolog, subfamily C, member 22	0.012
HOXD1	homeobox D1	0.012
GLI1	GLI family zinc finger 1	0.012
IRX5	iroquois homeobox 5	0.012
FGF9	fibroblast growth factor 9 (glia-activating factor)	0.012
VASH2	vasohibin 2	0.012
GPR12	G protein-coupled receptor 12	0.012
EDN3	endothelin 3	0.012
HTR2B	5-hydroxytryptamine (serotonin) receptor 2B	0.012
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.012
HOXA4	homeobox A4	0.012
GUCY1A2	guanylate cyclase 1, soluble, alpha 2	0.012
PTCH1	patched 1	0.012
ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)	0.012
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.012
KRT13	keratin 13	0.012
TMEM151A	transmembrane protein 151A	0.012
MSX2	msh homeobox 2	0.011
FBXO27	F-box protein 27	0.011
ZNF80	zinc finger protein 80	0.011
KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	0.011
C1QL1	complement component 1, q subcomponent-like 1	0.011
FOXL1	forkhead box L1	0.011
KREMEN2	kringle containing transmembrane protein 2	0.011
KIAA1644	KIAA1644	0.011
GLI2	GLI family zinc finger 2	0.011
SLITRK2	SLIT and NTRK-like family, member 2	0.011
GLDC	glycine dehydrogenase (decarboxylating)	0.011
PTGDR	prostaglandin D2 receptor (DP)	0.011
IL11	interleukin 11	0.011
LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.011
TGM5	transglutaminase 5	0.011
KLF14	Kruppel-like factor 14	0.011
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.011
PODN	podocan	0.011
GPR143	G protein-coupled receptor 143	0.011
PNOC	prepronociceptin	0.011
VEGFC	vascular endothelial growth factor C	0.011
INSM1	insulinoma-associated 1	0.011
CYP2A13	cytochrome P450, family 2, subfamily A, polypeptide 13	0.011
HOXC13	homeobox C13	0.011
DLX5	distal-less homeobox 5	0.011
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.011
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.011
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.011
TP53I11	tumor protein p53 inducible protein 11	0.011
WFDC5	WAP four-disulfide core domain 5	0.011
EMX2	empty spiracles homeobox 2	0.011
PAX2	paired box 2	0.011
PLXNA2	plexin A2	0.011
HOXD9	homeobox D9	0.011
SIX5	SIX homeobox 5	0.011
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.011
DLL4	delta-like 4 (Drosophila)	0.011
TG	thyroglobulin	0.011
MAP1A	microtubule-associated protein 1A	0.011
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.011
NNAT	neuronatin	0.011
SOX1	SRY (sex determining region Y)-box 1	0.011
NKX2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.011
ICOSLG	inducible T-cell co-stimulator ligand	0.011
GPR1	G protein-coupled receptor 1	0.011
C1orf194	chromosome 1 open reading frame 194	0.011
BMP3	bone morphogenetic protein 3	0.011
NOTUM	notum pectinacetylesterase homolog (Drosophila)	0.011
CDKL1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.011
ZNF469	zinc finger protein 469	0.011
FGF8	fibroblast growth factor 8 (androgen-induced)	0.011
IGDCC3	immunoglobulin superfamily, DCC subclass, member 3	0.010
ARSI	arylsulfatase family, member I	0.010
EPB49	erythrocyte membrane protein band 4.9 (dematin)	0.010
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.010
ALS2CL	ALS2 C-terminal like	0.010
ITGA9	integrin, alpha 9	0.010
SCARF2	scavenger receptor class F, member 2	0.010
RBP1	retinol binding protein 1, cellular	0.010
ALDH3A1	aldehyde dehydrogenase 3 family, member A1	0.010
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.010
ESPN	espin	0.010
MEOX1	mesenchyme homeobox 1	0.010
ATOH8	atonal homolog 8 (Drosophila)	0.010
FOXF1	forkhead box F1	0.010
CAPN6	calpain 6	0.010
RTN4R	reticulon 4 receptor	0.010
NTF4	neurotrophin 4	0.010
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.010
RASL10A	RAS-like, family 10, member A	0.010