IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

erythrocyte development

The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "erythrocyte development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "erythrocyte development" (in gray)

Name	Description	Probability	Func Analog Organism
TAL1	T-cell acute lymphocytic leukemia 1	0.997	Zebrafish Mouse
HBB	hemoglobin, beta	0.812
HBG2	hemoglobin, gamma G	0.758
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.716
GATA2	GATA binding protein 2	0.691	Human Zebrafish
SPTB	spectrin, beta, erythrocytic	0.616
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.599
ANK1	ankyrin 1, erythrocytic	0.551	Mouse
RBBP5	retinoblastoma binding protein 5	0.433
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.367
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.349
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.346
FBXO7	F-box protein 7	0.331
NCOR2	nuclear receptor corepressor 2	0.328
WDR5	WD repeat domain 5	0.327
RPL39	ribosomal protein L39	0.300
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.264
RHAG	Rh-associated glycoprotein	0.244	Mouse
HSPB1	heat shock 27kDa protein 1	0.237
PRPF38A	PRP38 pre-mRNA processing factor 38 (yeast) domain containing A	0.229
RPS27	ribosomal protein S27	0.212
RPS14	ribosomal protein S14	0.208
ZCCHC17	zinc finger, CCHC domain containing 17	0.184
RPS13	ribosomal protein S13	0.171
HCFC1	host cell factor C1 (VP16-accessory protein)	0.171
RPS18	ribosomal protein S18	0.163
RUNX1	runt-related transcription factor 1	0.162
RPLP2	ribosomal protein, large, P2	0.158
MKL1	megakaryoblastic leukemia (translocation) 1	0.152
AFF1	AF4/FMR2 family, member 1	0.144
TGS1	trimethylguanosine synthase 1	0.141
RHD	Rh blood group, D antigen	0.140	Mouse
GYPB	glycophorin B (MNS blood group)	0.133
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.131
INSR	insulin receptor	0.128
GAS7	growth arrest-specific 7	0.119
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.115
CCNT1	cyclin T1	0.112
CDK9	cyclin-dependent kinase 9	0.106
RPS11	ribosomal protein S11	0.106
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.105
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.100
KLF13	Kruppel-like factor 13	0.098
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.095
STAP2	signal transducing adaptor family member 2	0.093
MYOD1	myogenic differentiation 1	0.093
MED13	mediator complex subunit 13	0.092
RPS28	ribosomal protein S28	0.090
ALAS2	aminolevulinate, delta-, synthase 2	0.090
RHCE	Rh blood group, CcEe antigens	0.089	Mouse
HCFC2	host cell factor C2	0.085
SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	0.084
CDK19	cyclin-dependent kinase 19	0.083
NCOA1	nuclear receptor coactivator 1	0.081
PCDH9	protocadherin 9	0.080
BRD4	bromodomain containing 4	0.078
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.077
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.074
RPS15	ribosomal protein S15	0.073
MLLT1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.073
MYOCD	myocardin	0.069
AFF4	AF4/FMR2 family, member 4	0.069
HBD	hemoglobin, delta	0.067
TCF12	transcription factor 12	0.064
HBE1	hemoglobin, epsilon 1	0.062
PF4	platelet factor 4	0.062
ARID4B	AT rich interactive domain 4B (RBP1-like)	0.059
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.053
MYST1	MYST histone acetyltransferase 1	0.053
KLF1	Kruppel-like factor 1 (erythroid)	0.052	Mouse
HBZ	hemoglobin, zeta	0.051	Mouse
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.050
OSBP2	oxysterol binding protein 2	0.049
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.047
EPB42	erythrocyte membrane protein band 4.2	0.047
TBX5	T-box 5	0.045
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.043
HDAC5	histone deacetylase 5	0.043
MYOG	myogenin (myogenic factor 4)	0.042
CREBBP	CREB binding protein	0.042
RARA	retinoic acid receptor, alpha	0.041
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.040
ABI1	abl-interactor 1	0.040
IL2RB	interleukin 2 receptor, beta	0.040
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.039
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.039
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.037
MEN1	multiple endocrine neoplasia I	0.037
EP300	E1A binding protein p300	0.036
TRIM10	tripartite motif containing 10	0.035
JAK1	Janus kinase 1	0.034
KEL	Kell blood group, metallo-endopeptidase	0.034
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.033
LYL1	lymphoblastic leukemia derived sequence 1	0.033
CCNL1	cyclin L1	0.033
RPS19	ribosomal protein S19	0.032
MKL2	MKL/myocardin-like 2	0.032
JAK2	Janus kinase 2	0.031
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.031
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.031
ZBTB16	zinc finger and BTB domain containing 16	0.029
RPS4X	ribosomal protein S4, X-linked	0.029
KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.028
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.028
STAT5A	signal transducer and activator of transcription 5A	0.027	Zebrafish
PPAP2B	phosphatidic acid phosphatase type 2B	0.027
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.027
CCNG2	cyclin G2	0.027
TTN	titin	0.026
GOLM1	golgi membrane protein 1	0.026
RHOB	ras homolog gene family, member B	0.026
HIST1H3B	histone cluster 1, H3b	0.026
C5orf41	chromosome 5 open reading frame 41	0.026
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.026
GFI1B	growth factor independent 1B transcription repressor	0.025
RPS16	ribosomal protein S16	0.025
E2F3	E2F transcription factor 3	0.025
NCOA6	nuclear receptor coactivator 6	0.025
ZFPM1	zinc finger protein, multitype 1	0.025
LMO2	LIM domain only 2 (rhombotin-like 1)	0.024
PRRC2C	proline-rich coiled-coil 2C	0.024
CUX1	cut-like homeobox 1	0.023
PPARA	peroxisome proliferator-activated receptor alpha	0.023
DUSP1	dual specificity phosphatase 1	0.023
TKT	transketolase	0.023
KDM2A	lysine (K)-specific demethylase 2A	0.023
PGD	phosphogluconate dehydrogenase	0.023
SH2B1	SH2B adaptor protein 1	0.022
EPOR	erythropoietin receptor	0.022
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.022
SPAG9	sperm associated antigen 9	0.022
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.022
EPS8	epidermal growth factor receptor pathway substrate 8	0.022
GYPE	glycophorin E (MNS blood group)	0.022
RPS10	ribosomal protein S10	0.022
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.022
MED12	mediator complex subunit 12	0.022
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.021
RPS12	ribosomal protein S12	0.021
GYPA	glycophorin A (MNS blood group)	0.021
CHD8	chromodomain helicase DNA binding protein 8	0.021
NCOA3	nuclear receptor coactivator 3	0.021
TNPO1	transportin 1	0.021
HDAC9	histone deacetylase 9	0.021
IGF1R	insulin-like growth factor 1 receptor	0.021
TOLLIP	toll interacting protein	0.020
SMAD1	SMAD family member 1	0.020
FAM190B	family with sequence similarity 190, member B	0.020
HEXIM1	hexamethylene bis-acetamide inducible 1	0.019
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.019	Mouse
RPL36A	ribosomal protein L36a	0.019
AKAP13	A kinase (PRKA) anchor protein 13	0.019
NFE2	nuclear factor (erythroid-derived 2), 45kDa	0.019
WAC	WW domain containing adaptor with coiled-coil	0.019
ELF4	E74-like factor 4 (ets domain transcription factor)	0.019
MED25	mediator complex subunit 25	0.018
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.018
MKRN1	makorin ring finger protein 1	0.018
GHR	growth hormone receptor	0.018
EBF1	early B-cell factor 1	0.018
TALDO1	transaldolase 1	0.018
PAPD7	PAP associated domain containing 7	0.018
RPL38	ribosomal protein L38	0.018
ELL2	elongation factor, RNA polymerase II, 2	0.018
HBQ1	hemoglobin, theta 1	0.018
RPS20	ribosomal protein S20	0.018
MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	0.017
HAND2	heart and neural crest derivatives expressed 2	0.017
ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	0.017
SLA	Src-like-adaptor	0.017
GRB10	growth factor receptor-bound protein 10	0.017
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.017
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.017
TFR2	transferrin receptor 2	0.017
ESR2	estrogen receptor 2 (ER beta)	0.017
ADD1	adducin 1 (alpha)	0.016
ING2	inhibitor of growth family, member 2	0.016
KIAA1370	KIAA1370	0.016
SFPQ	splicing factor proline/glutamine-rich	0.016
GP1BA	glycoprotein Ib (platelet), alpha polypeptide	0.016
DDIT3	DNA-damage-inducible transcript 3	0.016
PAX5	paired box 5	0.016
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.016
PML	promyelocytic leukemia	0.016
HIPK2	homeodomain interacting protein kinase 2	0.016
POGK	pogo transposable element with KRAB domain	0.016
MASTL	microtubule associated serine/threonine kinase-like	0.016
THRAP3	thyroid hormone receptor associated protein 3	0.015
SFRP5	secreted frizzled-related protein 5	0.015
HBP1	HMG-box transcription factor 1	0.015
SENP7	SUMO1/sentrin specific peptidase 7	0.015
ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)	0.015
MBIP	MAP3K12 binding inhibitory protein 1	0.015
C5orf4	chromosome 5 open reading frame 4	0.015
RPL37A	ribosomal protein L37a	0.015
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.015
RAP1GAP	RAP1 GTPase activating protein	0.015
KBTBD7	kelch repeat and BTB (POZ) domain containing 7	0.015
EPC2	enhancer of polycomb homolog 2 (Drosophila)	0.015
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.015
HOXD12	homeobox D12	0.015
GATA5	GATA binding protein 5	0.015	Human
PRG2	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)	0.014
GLA	galactosidase, alpha	0.014
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.014
TCF4	transcription factor 4	0.014
PHF12	PHD finger protein 12	0.014
TRIB3	tribbles homolog 3 (Drosophila)	0.014
TOM1	target of myb1 (chicken)	0.014
HSPA1B	heat shock 70kDa protein 1B	0.014
CIR1	corepressor interacting with RBPJ, 1	0.014
PKM2	pyruvate kinase, muscle	0.014
STAT5B	signal transducer and activator of transcription 5B	0.014	Zebrafish
TADA2A	transcriptional adaptor 2A	0.014
OPTN	optineurin	0.014
BCOR	BCL6 corepressor	0.014
NUMB	numb homolog (Drosophila)	0.014
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.013
NFIL3	nuclear factor, interleukin 3 regulated	0.013
WDR45	WD repeat domain 45	0.013
DCLRE1B	DNA cross-link repair 1B	0.013
GATA3	GATA binding protein 3	0.013	Human
NUMA1	nuclear mitotic apparatus protein 1	0.013
PRMT2	protein arginine methyltransferase 2	0.013
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.013
OSBPL1A	oxysterol binding protein-like 1A	0.013
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.013
CHN2	chimerin (chimaerin) 2	0.013
POU2F3	POU class 2 homeobox 3	0.013
RPS24	ribosomal protein S24	0.013
BCL6	B-cell CLL/lymphoma 6	0.013	Mouse
RPS23	ribosomal protein S23	0.013
CHD1	chromodomain helicase DNA binding protein 1	0.013
RPS9	ribosomal protein S9	0.013
DDX6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.013
CALCOCO1	calcium binding and coiled-coil domain 1	0.013
EGF	epidermal growth factor	0.013
NUSAP1	nucleolar and spindle associated protein 1	0.012
WASF2	WAS protein family, member 2	0.012
SERTAD1	SERTA domain containing 1	0.012
MED13L	mediator complex subunit 13-like	0.012
GFI1	growth factor independent 1 transcription repressor	0.012
MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	0.012
FAM65A	family with sequence similarity 65, member A	0.012
HOXA10	homeobox A10	0.012
NFX1	nuclear transcription factor, X-box binding 1	0.012
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.012
PLEKHO1	pleckstrin homology domain containing, family O member 1	0.012
SH3RF3	SH3 domain containing ring finger 3	0.012
SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.012
SP1	Sp1 transcription factor	0.012
KDM5A	lysine (K)-specific demethylase 5A	0.012
HOXB9	homeobox B9	0.012
SAP30L	SAP30-like	0.012
SETD1A	SET domain containing 1A	0.012
HNF4A	hepatocyte nuclear factor 4, alpha	0.012
FOSL2	FOS-like antigen 2	0.012
PRDM8	PR domain containing 8	0.012
GYPC	glycophorin C (Gerbich blood group)	0.012
CTBP1	C-terminal binding protein 1	0.012
DOCK2	dedicator of cytokinesis 2	0.012
MED18	mediator complex subunit 18	0.012
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.012
AHSP	alpha hemoglobin stabilizing protein	0.011
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.011
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.011
EPB49	erythrocyte membrane protein band 4.9 (dematin)	0.011
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.011
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.011
RXRB	retinoid X receptor, beta	0.011
ALS2	amyotrophic lateral sclerosis 2 (juvenile)	0.011
VAV1	vav 1 guanine nucleotide exchange factor	0.011
MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	0.011
KAT2B	K(lysine) acetyltransferase 2B	0.011
RPS25	ribosomal protein S25	0.011
RPS3	ribosomal protein S3	0.011
DHH	desert hedgehog	0.011
AMHR2	anti-Mullerian hormone receptor, type II	0.011
PRTN3	proteinase 3	0.011
ARHGAP15	Rho GTPase activating protein 15	0.011
MEF2C	myocyte enhancer factor 2C	0.011
LRPAP1	low density lipoprotein receptor-related protein associated protein 1	0.011
HERPUD2	HERPUD family member 2	0.011
PPPDE1	PPPDE peptidase domain containing 1	0.011
KIAA0930	KIAA0930	0.011
PRC1	protein regulator of cytokinesis 1	0.011
WASF1	WAS protein family, member 1	0.011
TRIM23	tripartite motif containing 23	0.011
TSC22D3	TSC22 domain family, member 3	0.011
GATA4	GATA binding protein 4	0.011	Human
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.011
BHLHE23	basic helix-loop-helix family, member e23	0.011
AKT1S1	AKT1 substrate 1 (proline-rich)	0.011
LTK	leukocyte receptor tyrosine kinase	0.011
CA1	carbonic anhydrase I	0.011
POMGNT1	protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase	0.011
GAPVD1	GTPase activating protein and VPS9 domains 1	0.011
IRS1	insulin receptor substrate 1	0.011
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.011
ALX4	ALX homeobox 4	0.011
C3orf10	chromosome 3 open reading frame 10	0.011
CISH	cytokine inducible SH2-containing protein	0.010
DNAJB14	DnaJ (Hsp40) homolog, subfamily B, member 14	0.010
APOBR	apolipoprotein B receptor	0.010
RPS15A	ribosomal protein S15a	0.010
PIM1	pim-1 oncogene	0.010
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.010
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.010
SCAPER	S-phase cyclin A-associated protein in the ER	0.010
PGAM5	phosphoglycerate mutase family member 5	0.010
FRK	fyn-related kinase	0.010
PARVG	parvin, gamma	0.010
C10orf46	chromosome 10 open reading frame 46	0.010
FYCO1	FYVE and coiled-coil domain containing 1	0.010
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.010
CORO1A	coronin, actin binding protein, 1A	0.010
PDZK1IP1	PDZK1 interacting protein 1	0.010
PGR	progesterone receptor	0.010
SH3RF1	SH3 domain containing ring finger 1	0.010
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.010
ATG4A	ATG4 autophagy related 4 homolog A (S. cerevisiae)	0.010
SPIN1	spindlin 1	0.010
HMGXB4	HMG box domain containing 4	0.010
PPIG	peptidylprolyl isomerase G (cyclophilin G)	0.010
HEMGN	hemogen	0.010
FAM134A	family with sequence similarity 134, member A	0.010
BTG2	BTG family, member 2	0.010
RXRG	retinoid X receptor, gamma	0.010