IMP: Integrative Multi-species Prediction

Homo sapiens

2 genes annotated in human

motor neuron axon guidance

The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "motor neuron axon guidance"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "motor neuron axon guidance" (in gray)

Name	Description	Probability	Func Analog Organism
JAG1	jagged 1	0.999
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.998
EGFR	epidermal growth factor receptor	0.998
VEGFA	vascular endothelial growth factor A	0.994
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.991	Fly
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.988
ZYX	zyxin	0.987
CHRD	chordin	0.982
TAL1	T-cell acute lymphocytic leukemia 1	0.980
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.978
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.975	Worm Fly
PLCG1	phospholipase C, gamma 1	0.969
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.968
FLNA	filamin A, alpha	0.961	Fly
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.948
PSEN1	presenilin 1	0.933
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.921
ATN1	atrophin 1	0.912
ARHGAP1	Rho GTPase activating protein 1	0.903
GRB2	growth factor receptor-bound protein 2	0.900
FLNB	filamin B, beta	0.847	Fly
PAX3	paired box 3	0.836
XIRP1	xin actin-binding repeat containing 1	0.826
SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	0.813
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.802	Fly
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.796
RIN1	Ras and Rab interactor 1	0.785
GHR	growth hormone receptor	0.785
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.778	Fly
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.773
CTNND1	catenin (cadherin-associated protein), delta 1	0.772
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.767
SOX10	SRY (sex determining region Y)-box 10	0.745
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.734
MYH9	myosin, heavy chain 9, non-muscle	0.717
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.703
DPYSL4	dihydropyrimidinase-like 4	0.638
JUP	junction plakoglobin	0.602
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.601
PTK2	PTK2 protein tyrosine kinase 2	0.554
LAT	linker for activation of T cells	0.548
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.529
PGF	placental growth factor	0.528
SMAD3	SMAD family member 3	0.525
NTN1	netrin 1	0.523	Fly
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.518
SORBS1	sorbin and SH3 domain containing 1	0.505
CPE	carboxypeptidase E	0.483
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.467
MSN	moesin	0.441
ZNF512B	zinc finger protein 512B	0.440
NRP1	neuropilin 1	0.428	Zebrafish Mouse
FN1	fibronectin 1	0.410
TCF4	transcription factor 4	0.408
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.406
DLL1	delta-like 1 (Drosophila)	0.401
NOTCH1	notch 1	0.394	Fly
MYO10	myosin X	0.392
SH2B3	SH2B adaptor protein 3	0.375
BMP7	bone morphogenetic protein 7	0.374
DCC	deleted in colorectal carcinoma	0.374	Fly
DPP4	dipeptidyl-peptidase 4	0.373
AXIN1	axin 1	0.362
CDH5	cadherin 5, type 2 (vascular endothelium)	0.358
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.356
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.355
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.347	Fly
FYN	FYN oncogene related to SRC, FGR, YES	0.335
SOX11	SRY (sex determining region Y)-box 11	0.332
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.316
EZR	ezrin	0.315
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.307
CSNK1E	casein kinase 1, epsilon	0.298
JAG2	jagged 2	0.297
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.286
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.284	Mouse
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.267
CD44	CD44 molecule (Indian blood group)	0.266
LPXN	leupaxin	0.266
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.263
PCDH17	protocadherin 17	0.263
CCNK	cyclin K	0.261
WIPF1	WAS/WASL interacting protein family, member 1	0.259
PSEN2	presenilin 2 (Alzheimer disease 4)	0.256
EGR3	early growth response 3	0.255
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.254
SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.250	Fly
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.248
SORBS2	sorbin and SH3 domain containing 2	0.247
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.246
TGFB3	transforming growth factor, beta 3	0.242
LRRK2	leucine-rich repeat kinase 2	0.241
NOTCH3	notch 3	0.235	Fly
VAV2	vav 2 guanine nucleotide exchange factor	0.226
GSK3B	glycogen synthase kinase 3 beta	0.217
SOX21	SRY (sex determining region Y)-box 21	0.217
MUC1	mucin 1, cell surface associated	0.216
PTPRD	protein tyrosine phosphatase, receptor type, D	0.211	Fly
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.211
ACTN1	actinin, alpha 1	0.208
ATXN1	ataxin 1	0.207
RADIL	Ras association and DIL domains	0.207
NOTCH2	notch 2	0.206	Fly
RUNX1	runt-related transcription factor 1	0.205
TEK	TEK tyrosine kinase, endothelial	0.202
NCKIPSD	NCK interacting protein with SH3 domain	0.200
WT1	Wilms tumor 1	0.199
SOCS1	suppressor of cytokine signaling 1	0.193
ACP5	acid phosphatase 5, tartrate resistant	0.191
ESR1	estrogen receptor 1	0.187
HOXA5	homeobox A5	0.187
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.186
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.186
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.184
NCF1	neutrophil cytosolic factor 1	0.179
TLN1	talin 1	0.179
VCAN	versican	0.178
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.175
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.175
SH3RF1	SH3 domain containing ring finger 1	0.175
BAK1	BCL2-antagonist/killer 1	0.167
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.166
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.166
MEOX2	mesenchyme homeobox 2	0.166
POU3F2	POU class 3 homeobox 2	0.165	Fly
LAMA4	laminin, alpha 4	0.164
HSPG2	heparan sulfate proteoglycan 2	0.163
CAV1	caveolin 1, caveolae protein, 22kDa	0.162
EGR1	early growth response 1	0.158
MARCKS	myristoylated alanine-rich protein kinase C substrate	0.157
DPPA4	developmental pluripotency associated 4	0.155
SMAD9	SMAD family member 9	0.152
DNM1	dynamin 1	0.151
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.150
BMP2	bone morphogenetic protein 2	0.149
DOK4	docking protein 4	0.148
NRP2	neuropilin 2	0.144	Mouse
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.143
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.141
SLIT2	slit homolog 2 (Drosophila)	0.139
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.139
CADM4	cell adhesion molecule 4	0.138
CABLES1	Cdk5 and Abl enzyme substrate 1	0.137
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.137
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.135
CSNK1D	casein kinase 1, delta	0.133
CELF2	CUGBP, Elav-like family member 2	0.132
HOXD3	homeobox D3	0.132
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.132
SMAD1	SMAD family member 1	0.131
IRS4	insulin receptor substrate 4	0.131
NOTCH2NL	notch 2 N-terminal like	0.131
PFN1	profilin 1	0.131
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	0.129
GAB1	GRB2-associated binding protein 1	0.128
NBPF10	neuroblastoma breakpoint family, member 10	0.128
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.127
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.126
RHOG	ras homolog gene family, member G (rho G)	0.126
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.126
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.125
EFNB1	ephrin-B1	0.124
EHMT2	euchromatic histone-lysine N-methyltransferase 2	0.123
TRIO	triple functional domain (PTPRF interacting)	0.121
TNS3	tensin 3	0.121
GRB10	growth factor receptor-bound protein 10	0.121
RECK	reversion-inducing-cysteine-rich protein with kazal motifs	0.120
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.120
MCC	mutated in colorectal cancers	0.120
QKI	quaking homolog, KH domain RNA binding (mouse)	0.120
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.119
PKP4	plakophilin 4	0.119
LRP6	low density lipoprotein receptor-related protein 6	0.119
BNC2	basonuclin 2	0.118
PFN2	profilin 2	0.117
WDR1	WD repeat domain 1	0.116
SFRP1	secreted frizzled-related protein 1	0.116
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.116
TECPR1	tectonin beta-propeller repeat containing 1	0.115
FBLIM1	filamin binding LIM protein 1	0.115
WASF1	WAS protein family, member 1	0.114
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.113
ANTXR2	anthrax toxin receptor 2	0.112
SORBS3	sorbin and SH3 domain containing 3	0.112
EFNB2	ephrin-B2	0.112
CEP164	centrosomal protein 164kDa	0.111
SMO	smoothened homolog (Drosophila)	0.111
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.110
LCK	lymphocyte-specific protein tyrosine kinase	0.109
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.109
VAV3	vav 3 guanine nucleotide exchange factor	0.108
BCAR1	breast cancer anti-estrogen resistance 1	0.107
PRKCA	protein kinase C, alpha	0.107
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.107
GLT25D1	glycosyltransferase 25 domain containing 1	0.106
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.105
LMNA	lamin A/C	0.105
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.105
TGFB1	transforming growth factor, beta 1	0.104
HOXA4	homeobox A4	0.104
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.102
SH2D2A	SH2 domain containing 2A	0.102
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.102
TAGLN2	transgelin 2	0.101
DPPA2	developmental pluripotency associated 2	0.101
DLG5	discs, large homolog 5 (Drosophila)	0.101
MYOZ1	myozenin 1	0.101
UNC5C	unc-5 homolog C (C. elegans)	0.101	Fly
CD22	CD22 molecule	0.100
IQGAP1	IQ motif containing GTPase activating protein 1	0.100
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.099
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.099
POU3F1	POU class 3 homeobox 1	0.099	Fly
AQP1	aquaporin 1 (Colton blood group)	0.099
BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	0.099
TGFA	transforming growth factor, alpha	0.099
RBMS3	RNA binding motif, single stranded interacting protein 3	0.099
EPHA3	EPH receptor A3	0.099
ALAS1	aminolevulinate, delta-, synthase 1	0.098
NCKAP1	NCK-associated protein 1	0.098
TCF12	transcription factor 12	0.097
BCL2L1	BCL2-like 1	0.097
PITX1	paired-like homeodomain 1	0.096
MYOD1	myogenic differentiation 1	0.096
XIAP	X-linked inhibitor of apoptosis	0.096
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.095
GRB7	growth factor receptor-bound protein 7	0.095
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.094
TES	testis derived transcript (3 LIM domains)	0.094
MAP1B	microtubule-associated protein 1B	0.093
TP73	tumor protein p73	0.093
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.093
EPHB2	EPH receptor B2	0.092
ABI2	abl-interactor 2	0.092
SKIL	SKI-like oncogene	0.091
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.091
FGFR2	fibroblast growth factor receptor 2	0.090
MAML1	mastermind-like 1 (Drosophila)	0.090
NEUROD1	neurogenic differentiation 1	0.090
SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.089
FLRT2	fibronectin leucine rich transmembrane protein 2	0.089
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.089
NOVA1	neuro-oncological ventral antigen 1	0.088
CTBP1	C-terminal binding protein 1	0.088
DDR1	discoidin domain receptor tyrosine kinase 1	0.088
PLEC	plectin	0.088
FLT4	fms-related tyrosine kinase 4	0.087
DUSP6	dual specificity phosphatase 6	0.087
DCX	doublecortin	0.087
CAPN1	calpain 1, (mu/I) large subunit	0.087
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.086
HES1	hairy and enhancer of split 1, (Drosophila)	0.086
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.085
GAS7	growth arrest-specific 7	0.085
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.085
LGALS1	lectin, galactoside-binding, soluble, 1	0.084
TPM4	tropomyosin 4	0.084
GJA1	gap junction protein, alpha 1, 43kDa	0.084
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.084
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.084
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.084
FAM110C	family with sequence similarity 110, member C	0.084
ACTN4	actinin, alpha 4	0.083
MAPT	microtubule-associated protein tau	0.082
PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	0.082
GPM6B	glycoprotein M6B	0.082
DOK6	docking protein 6	0.082
EPAS1	endothelial PAS domain protein 1	0.082
TGFBR1	transforming growth factor, beta receptor 1	0.082
PPP1R12C	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.082
ISL1	ISL LIM homeobox 1	0.081	Fly
PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.081
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.080
GLIS2	GLIS family zinc finger 2	0.080
ACTB	actin, beta	0.080
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.080	Fly
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.080	Fly
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.080
ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	0.079
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.079
MAPK1	mitogen-activated protein kinase 1	0.079
CLDN7	claudin 7	0.078
LMX1A	LIM homeobox transcription factor 1, alpha	0.078
PDLIM7	PDZ and LIM domain 7 (enigma)	0.078
CHD3	chromodomain helicase DNA binding protein 3	0.078
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.078
HOXB5	homeobox B5	0.078
HOXB13	homeobox B13	0.077
GPR161	G protein-coupled receptor 161	0.077
POU3F3	POU class 3 homeobox 3	0.077	Fly
CAPNS1	calpain, small subunit 1	0.077
STK10	serine/threonine kinase 10	0.077
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.077
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.077
BAHD1	bromo adjacent homology domain containing 1	0.076
TGFB2	transforming growth factor, beta 2	0.076
PEA15	phosphoprotein enriched in astrocytes 15	0.075
HOXB9	homeobox B9	0.075
PLAUR	plasminogen activator, urokinase receptor	0.074
MRC2	mannose receptor, C type 2	0.074
KCNRG	potassium channel regulator	0.074
FGFR1	fibroblast growth factor receptor 1	0.074
TRIP6	thyroid hormone receptor interactor 6	0.074
TRO	trophinin	0.073
FAM46D	family with sequence similarity 46, member D	0.073
ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	0.073
WSCD1	WSC domain containing 1	0.072
HOXD11	homeobox D11	0.072
DPYSL2	dihydropyrimidinase-like 2	0.072
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.071
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.071
TAOK1	TAO kinase 1	0.071
NPAS1	neuronal PAS domain protein 1	0.071
FOXF1	forkhead box F1	0.070
ZFPM2	zinc finger protein, multitype 2	0.070
PTPRS	protein tyrosine phosphatase, receptor type, S	0.070	Fly
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.070
SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4	0.070
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.070
STC1	stanniocalcin 1	0.069
TNRC6B	trinucleotide repeat containing 6B	0.069
HOXA10	homeobox A10	0.069
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.069
SPTBN1	spectrin, beta, non-erythrocytic 1	0.068
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.068
RDX	radixin	0.068
MAP2	microtubule-associated protein 2	0.068
ADAM19	ADAM metallopeptidase domain 19	0.067
HOXD9	homeobox D9	0.067
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.067
CDK6	cyclin-dependent kinase 6	0.067
KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.067
LDLR	low density lipoprotein receptor	0.066
PAX6	paired box 6	0.066
COL13A1	collagen, type XIII, alpha 1	0.066
NAV1	neuron navigator 1	0.066
COL5A1	collagen, type V, alpha 1	0.066
OLIG2	oligodendrocyte lineage transcription factor 2	0.066
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	0.066
SNAI1	snail homolog 1 (Drosophila)	0.066
CCR5	chemokine (C-C motif) receptor 5	0.066
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.066
JAK1	Janus kinase 1	0.066
APP	amyloid beta (A4) precursor protein	0.066
NCAM1	neural cell adhesion molecule 1	0.065
ANGPTL2	angiopoietin-like 2	0.065
EFS	embryonal Fyn-associated substrate	0.065
EDIL3	EGF-like repeats and discoidin I-like domains 3	0.065
PTCH1	patched 1	0.065
RAX	retina and anterior neural fold homeobox	0.065
SLCO2A1	solute carrier organic anion transporter family, member 2A1	0.065
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.065
NEU4	sialidase 4	0.064
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.064
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.064
TRIM63	tripartite motif containing 63	0.064
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.064
FGD1	FYVE, RhoGEF and PH domain containing 1	0.064
NFIB	nuclear factor I/B	0.064
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.064
DCBLD2	discoidin, CUB and LCCL domain containing 2	0.064
CHN2	chimerin (chimaerin) 2	0.064
EPS8	epidermal growth factor receptor pathway substrate 8	0.064
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.064
PTK7	PTK7 protein tyrosine kinase 7	0.064
IL3RA	interleukin 3 receptor, alpha (low affinity)	0.063
ITGB4	integrin, beta 4	0.063
APC2	adenomatosis polyposis coli 2	0.063
GLI3	GLI family zinc finger 3	0.063
NOVA2	neuro-oncological ventral antigen 2	0.063
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.062
TBX2	T-box 2	0.062
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.062
ARL4C	ADP-ribosylation factor-like 4C	0.062
ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.062
FGFR3	fibroblast growth factor receptor 3	0.062
ZNF205	zinc finger protein 205	0.062
HOXB3	homeobox B3	0.062
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.062
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.062
ZFP36L2	zinc finger protein 36, C3H type-like 2	0.061
HOXA2	homeobox A2	0.061	Mouse
HOXA6	homeobox A6	0.061
RELN	reelin	0.061
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.061
TCAP	titin-cap (telethonin)	0.061
NOTCH4	notch 4	0.061	Fly
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.060
GLI1	GLI family zinc finger 1	0.060
EFNA5	ephrin-A5	0.060
HOXA11	homeobox A11	0.060
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.060
RAI1	retinoic acid induced 1	0.060
ACTN2	actinin, alpha 2	0.060
PTPRG	protein tyrosine phosphatase, receptor type, G	0.060
CD151	CD151 molecule (Raph blood group)	0.060
MYOT	myotilin	0.060
IGFBP5	insulin-like growth factor binding protein 5	0.060
MMRN2	multimerin 2	0.060
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.060
RIN2	Ras and Rab interactor 2	0.059
LPP	LIM domain containing preferred translocation partner in lipoma	0.059
TRIL	TLR4 interactor with leucine-rich repeats	0.059
FGF1	fibroblast growth factor 1 (acidic)	0.059
ETV1	ets variant 1	0.059
NXPH4	neurexophilin 4	0.059
SOX18	SRY (sex determining region Y)-box 18	0.059
ALX3	ALX homeobox 3	0.059
FBLN1	fibulin 1	0.059
IRS1	insulin receptor substrate 1	0.058
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.058
HMX1	H6 family homeobox 1	0.058
HOXA7	homeobox A7	0.058
ARL15	ADP-ribosylation factor-like 15	0.058
C1QL1	complement component 1, q subcomponent-like 1	0.058
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.058
COL4A6	collagen, type IV, alpha 6	0.058
GATAD2B	GATA zinc finger domain containing 2B	0.058
DEF6	differentially expressed in FDCP 6 homolog (mouse)	0.057
PLP1	proteolipid protein 1	0.057
COTL1	coactosin-like 1 (Dictyostelium)	0.057
FZD7	frizzled homolog 7 (Drosophila)	0.057
BARX1	BARX homeobox 1	0.057
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.057
SH2D3A	SH2 domain containing 3A	0.057
EPHB4	EPH receptor B4	0.056
NKD2	naked cuticle homolog 2 (Drosophila)	0.056
CLNK	cytokine-dependent hematopoietic cell linker	0.056
ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.056
FLI1	Friend leukemia virus integration 1	0.056
TFG	TRK-fused gene	0.056
EDNRB	endothelin receptor type B	0.055
NAV3	neuron navigator 3	0.055
SOX1	SRY (sex determining region Y)-box 1	0.055
SUPT6H	suppressor of Ty 6 homolog (S. cerevisiae)	0.055
NCSTN	nicastrin	0.055
PCDH7	protocadherin 7	0.055
CNTFR	ciliary neurotrophic factor receptor	0.055
PDE4B	phosphodiesterase 4B, cAMP-specific	0.055
PDE10A	phosphodiesterase 10A	0.055
DAAM1	dishevelled associated activator of morphogenesis 1	0.054
DLGAP4	discs, large (Drosophila) homolog-associated protein 4	0.054
PCDH9	protocadherin 9	0.054
FOXD3	forkhead box D3	0.054
FZD1	frizzled homolog 1 (Drosophila)	0.054
FGF3	fibroblast growth factor 3	0.054
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.054
MAP2K1	mitogen-activated protein kinase kinase 1	0.054
ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	0.054
MYH10	myosin, heavy chain 10, non-muscle	0.054
PCDHB11	protocadherin beta 11	0.054
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.053
NNAT	neuronatin	0.053
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.053
NRG1	neuregulin 1	0.053
PLXNB1	plexin B1	0.053
COL2A1	collagen, type II, alpha 1	0.053
APLNR	apelin receptor	0.053
DBN1	drebrin 1	0.053
MEIS2	Meis homeobox 2	0.053
AR	androgen receptor	0.053
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.053
DOCK1	dedicator of cytokinesis 1	0.053
DAB1	disabled homolog 1 (Drosophila)	0.053
NHLH1	nescient helix loop helix 1	0.053
EGFL7	EGF-like-domain, multiple 7	0.053
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.053
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.052
SHB	Src homology 2 domain containing adaptor protein B	0.052
HMGA2	high mobility group AT-hook 2	0.052
GATA2	GATA binding protein 2	0.052	Fly
UNC5B	unc-5 homolog B (C. elegans)	0.052	Worm Fly
PTPRR	protein tyrosine phosphatase, receptor type, R	0.052
WASF2	WAS protein family, member 2	0.051
CISH	cytokine inducible SH2-containing protein	0.051
PBX1	pre-B-cell leukemia homeobox 1	0.051
KIAA1377	KIAA1377	0.051
COL14A1	collagen, type XIV, alpha 1	0.051
AMN	amnionless homolog (mouse)	0.051
DLX2	distal-less homeobox 2	0.051
RUNX2	runt-related transcription factor 2	0.051
PRNP	prion protein	0.051
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.051
KRTAP4-12	keratin associated protein 4-12	0.051
CFL1	cofilin 1 (non-muscle)	0.051
KCNK3	potassium channel, subfamily K, member 3	0.050
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.050	Fly
RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	0.050
RHOC	ras homolog gene family, member C	0.050	Fly
GPC1	glypican 1	0.050
CREB5	cAMP responsive element binding protein 5	0.050
LHX1	LIM homeobox 1	0.050	Mouse
EFNB3	ephrin-B3	0.050
ZBTB32	zinc finger and BTB domain containing 32	0.050
ENO1	enolase 1, (alpha)	0.050
FER	fer (fps/fes related) tyrosine kinase	0.050
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.049
MN1	meningioma (disrupted in balanced translocation) 1	0.049
KLF12	Kruppel-like factor 12	0.049
RHOA	ras homolog gene family, member A	0.049	Fly
CEP170	centrosomal protein 170kDa	0.049
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.049
TSHZ3	teashirt zinc finger homeobox 3	0.049
LHX5	LIM homeobox 5	0.049
SH3GL3	SH3-domain GRB2-like 3	0.049
PHLDB1	pleckstrin homology-like domain, family B, member 1	0.049
NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor	0.049
NKX2-8	NK2 homeobox 8	0.049
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.048
PLXNA2	plexin A2	0.048
EGF	epidermal growth factor	0.048
LZTS1	leucine zipper, putative tumor suppressor 1	0.048
FAM110A	family with sequence similarity 110, member A	0.048
ZFPM1	zinc finger protein, multitype 1	0.048
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.048
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.048
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.048
LMO2	LIM domain only 2 (rhombotin-like 1)	0.048
TTC28	tetratricopeptide repeat domain 28	0.048
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.048
EPHB1	EPH receptor B1	0.048
NKX3-2	NK3 homeobox 2	0.047
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.047
COL6A1	collagen, type VI, alpha 1	0.047
MEF2C	myocyte enhancer factor 2C	0.047
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.047
AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	0.047
OSBPL8	oxysterol binding protein-like 8	0.047
RIMS4	regulating synaptic membrane exocytosis 4	0.047
BMP8A	bone morphogenetic protein 8a	0.047
PTK6	PTK6 protein tyrosine kinase 6	0.047
GPC3	glypican 3	0.047
NGFR	nerve growth factor receptor	0.047
SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.047
KCNK2	potassium channel, subfamily K, member 2	0.047
MEIS1	Meis homeobox 1	0.047
EPHA4	EPH receptor A4	0.047	Mouse
VEGFC	vascular endothelial growth factor C	0.047
PLAU	plasminogen activator, urokinase	0.047
FGFR4	fibroblast growth factor receptor 4	0.046
ARHGAP15	Rho GTPase activating protein 15	0.046
ONECUT2	one cut homeobox 2	0.046
CCND2	cyclin D2	0.046
TNC	tenascin C	0.046
LAMA5	laminin, alpha 5	0.046
TBX5	T-box 5	0.046
ITGB7	integrin, beta 7	0.046
ITGA8	integrin, alpha 8	0.046
NEO1	neogenin 1	0.046	Fly
PTN	pleiotrophin	0.046
POMC	proopiomelanocortin	0.046
MBNL1	muscleblind-like (Drosophila)	0.046
INSM1	insulinoma-associated 1	0.046
DLL4	delta-like 4 (Drosophila)	0.046
SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.046
HUNK	hormonally up-regulated Neu-associated kinase	0.045
ADCY7	adenylate cyclase 7	0.045
NFASC	neurofascin	0.045
FOXL1	forkhead box L1	0.045
CALCA	calcitonin-related polypeptide alpha	0.045
NKX6-1	NK6 homeobox 1	0.045
ACSL4	acyl-CoA synthetase long-chain family member 4	0.045
FRMD5	FERM domain containing 5	0.045
CNTN1	contactin 1	0.045
OCLN	occludin	0.045
PLSCR4	phospholipid scramblase 4	0.045
ENG	endoglin	0.045
BLK	B lymphoid tyrosine kinase	0.045
SCUBE1	signal peptide, CUB domain, EGF-like 1	0.045
MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)	0.044
PAX2	paired box 2	0.044
MSX1	msh homeobox 1	0.044
S1PR1	sphingosine-1-phosphate receptor 1	0.044
DCLK1	doublecortin-like kinase 1	0.044
HEG1	HEG homolog 1 (zebrafish)	0.044
FOXB1	forkhead box B1	0.044
ZFYVE9	zinc finger, FYVE domain containing 9	0.044
MECOM	MDS1 and EVI1 complex locus	0.044
C9orf100	chromosome 9 open reading frame 100	0.044
FOXA2	forkhead box A2	0.044
CAPN6	calpain 6	0.044
DUSP3	dual specificity phosphatase 3	0.044
HOXA3	homeobox A3	0.044
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.044
SSTR5	somatostatin receptor 5	0.044
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.044
CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2	0.044
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.043
FGF7	fibroblast growth factor 7	0.043
PXN	paxillin	0.043
FRMD6	FERM domain containing 6	0.043
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.043
PTPRB	protein tyrosine phosphatase, receptor type, B	0.043	Fly
DMWD	dystrophia myotonica, WD repeat containing	0.043
LPHN3	latrophilin 3	0.043
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.043
EPHA2	EPH receptor A2	0.043
CABLES2	Cdk5 and Abl enzyme substrate 2	0.043
HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	0.043
SNCAIP	synuclein, alpha interacting protein	0.043
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.043
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.043
RASAL2	RAS protein activator like 2	0.043
SNIP1	Smad nuclear interacting protein 1	0.043
KLF7	Kruppel-like factor 7 (ubiquitous)	0.042
PITX2	paired-like homeodomain 2	0.042
TGFBR3	transforming growth factor, beta receptor III	0.042
DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.042
NPAS3	neuronal PAS domain protein 3	0.042
EPHA5	EPH receptor A5	0.042
SOX17	SRY (sex determining region Y)-box 17	0.042
VAX2	ventral anterior homeobox 2	0.042
TOM1L1	target of myb1 (chicken)-like 1	0.042
CBX4	chromobox homolog 4	0.042
DOCK4	dedicator of cytokinesis 4	0.042
ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9	0.042
MATK	megakaryocyte-associated tyrosine kinase	0.042
SFRP4	secreted frizzled-related protein 4	0.042
ZNF331	zinc finger protein 331	0.042
OSBPL3	oxysterol binding protein-like 3	0.042
SDC1	syndecan 1	0.042
SHOX2	short stature homeobox 2	0.042
ZBTB16	zinc finger and BTB domain containing 16	0.042
RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	0.042
ZBTB20	zinc finger and BTB domain containing 20	0.042
CHRDL1	chordin-like 1	0.042
SOX9	SRY (sex determining region Y)-box 9	0.042
ABI3BP	ABI family, member 3 (NESH) binding protein	0.042
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.042
MAP1A	microtubule-associated protein 1A	0.041
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.041
CD83	CD83 molecule	0.041
TRAPPC6A	trafficking protein particle complex 6A	0.041
FGF10	fibroblast growth factor 10	0.041
LMO1	LIM domain only 1 (rhombotin 1)	0.041
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.041
GAP43	growth associated protein 43	0.041
NEUROG3	neurogenin 3	0.041
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.041
FNDC3B	fibronectin type III domain containing 3B	0.041
CIB1	calcium and integrin binding 1 (calmyrin)	0.041
APH1A	anterior pharynx defective 1 homolog A (C. elegans)	0.041
WNT3	wingless-type MMTV integration site family, member 3	0.041
HDC	histidine decarboxylase	0.041
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.041
DLC1	deleted in liver cancer 1	0.041
BRSK2	BR serine/threonine kinase 2	0.041
SOBP	sine oculis binding protein homolog (Drosophila)	0.041
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.041	Fly
CDX2	caudal type homeobox 2	0.041
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.041	Fly
GEM	GTP binding protein overexpressed in skeletal muscle	0.041
EVI2B	ecotropic viral integration site 2B	0.041
ACPP	acid phosphatase, prostate	0.041
WNT11	wingless-type MMTV integration site family, member 11	0.041
SEPT4	septin 4	0.040
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.040
PROX1	prospero homeobox 1	0.040
PPFIA3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	0.040
PDGFA	platelet-derived growth factor alpha polypeptide	0.040
COL4A2	collagen, type IV, alpha 2	0.040
HOXB6	homeobox B6	0.040
SRGAP3	SLIT-ROBO Rho GTPase activating protein 3	0.040
ACAN	aggrecan	0.040
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.040
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.040
COL4A5	collagen, type IV, alpha 5	0.040
SOX4	SRY (sex determining region Y)-box 4	0.040
CALCR	calcitonin receptor	0.040
PAX7	paired box 7	0.040
SMAD6	SMAD family member 6	0.040
CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	0.040	Zebrafish
EVI2A	ecotropic viral integration site 2A	0.040
SNAPIN	SNAP-associated protein	0.040
EYA2	eyes absent homolog 2 (Drosophila)	0.040
LPPR4	lipid phosphate phosphatase-related protein type 4	0.040
PARM1	prostate androgen-regulated mucin-like protein 1	0.040
NKX2-2	NK2 homeobox 2	0.040	Zebrafish
CADM1	cell adhesion molecule 1	0.040
DENND5A	DENN/MADD domain containing 5A	0.040
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.040
PTPRK	protein tyrosine phosphatase, receptor type, K	0.040
CBX2	chromobox homolog 2	0.040
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.039
BMPR1A	bone morphogenetic protein receptor, type IA	0.039
EYA4	eyes absent homolog 4 (Drosophila)	0.039
PRDM5	PR domain containing 5	0.039
CTNNBIP1	catenin, beta interacting protein 1	0.039
ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	0.039
ZFHX4	zinc finger homeobox 4	0.039
SIX3	SIX homeobox 3	0.039
SHANK3	SH3 and multiple ankyrin repeat domains 3	0.039
PRKCQ	protein kinase C, theta	0.039
ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15	0.039
CSF1	colony stimulating factor 1 (macrophage)	0.039
PGM5	phosphoglucomutase 5	0.039
TAGAP	T-cell activation RhoGTPase activating protein	0.039
REPS2	RALBP1 associated Eps domain containing 2	0.039
PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme	0.039
FOXC1	forkhead box C1	0.039
SMAD7	SMAD family member 7	0.039
DPP6	dipeptidyl-peptidase 6	0.038
CXCL14	chemokine (C-X-C motif) ligand 14	0.038
C4orf31	chromosome 4 open reading frame 31	0.038
LRRN3	leucine rich repeat neuronal 3	0.038
UNC119	unc-119 homolog (C. elegans)	0.038
ACCN2	amiloride-sensitive cation channel 2, neuronal	0.038
PRPH	peripherin	0.038
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.038
UVRAG	UV radiation resistance associated gene	0.038
PTPRE	protein tyrosine phosphatase, receptor type, E	0.038	Fly
ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	0.038
FBXL7	F-box and leucine-rich repeat protein 7	0.038
SRGN	serglycin	0.038
ARL3	ADP-ribosylation factor-like 3	0.038
FEV	FEV (ETS oncogene family)	0.038
ANK1	ankyrin 1, erythrocytic	0.038
NCK2	NCK adaptor protein 2	0.038
SLCO5A1	solute carrier organic anion transporter family, member 5A1	0.038
PDGFC	platelet derived growth factor C	0.038
PCGF2	polycomb group ring finger 2	0.038
PCSK2	proprotein convertase subtilisin/kexin type 2	0.038
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.038
LRP2	low density lipoprotein receptor-related protein 2	0.038
LBX1	ladybird homeobox 1	0.038
IGF1R	insulin-like growth factor 1 receptor	0.037
BCHE	butyrylcholinesterase	0.037
MAB21L1	mab-21-like 1 (C. elegans)	0.037
TLN2	talin 2	0.037
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.037
LDB2	LIM domain binding 2	0.037
KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2	0.037
CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.037
EPHB3	EPH receptor B3	0.037
FBN2	fibrillin 2	0.037
PLVAP	plasmalemma vesicle associated protein	0.037
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.037
ADCY1	adenylate cyclase 1 (brain)	0.037
BHLHE23	basic helix-loop-helix family, member e23	0.037
GLI2	GLI family zinc finger 2	0.037	Zebrafish
FGF18	fibroblast growth factor 18	0.037
EFNA3	ephrin-A3	0.037
SATB1	SATB homeobox 1	0.037
IRX5	iroquois homeobox 5	0.037
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.037
DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.037
SNX17	sorting nexin 17	0.037
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.037	Mouse
PKNOX2	PBX/knotted 1 homeobox 2	0.037
PPP1R13L	protein phosphatase 1, regulatory (inhibitor) subunit 13 like	0.037