IMP: Integrative Multi-species Prediction

Homo sapiens

4 genes annotated in human

organ induction

The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "organ induction"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "organ induction" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	0.997
CREBBP	CREB binding protein	0.995
FGF1	fibroblast growth factor 1 (acidic)	0.993
FGFR1	fibroblast growth factor receptor 1	0.980	Mouse
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.963	Mouse Fly
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.959	Fly
FOXD3	forkhead box D3	0.947
BMPR1A	bone morphogenetic protein receptor, type IA	0.942
SP1	Sp1 transcription factor	0.910
NCOA2	nuclear receptor coactivator 2	0.870
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.851	Fly
FGF2	fibroblast growth factor 2 (basic)	0.844	Mouse
CSNK1E	casein kinase 1, epsilon	0.831
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.732
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.717
MYST2	MYST histone acetyltransferase 2	0.672
APC	adenomatous polyposis coli	0.622
LRP6	low density lipoprotein receptor-related protein 6	0.532
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.467
PLCG1	phospholipase C, gamma 1	0.452
FOXO1	forkhead box O1	0.379
AXIN1	axin 1	0.329
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.320
CTNNBIP1	catenin, beta interacting protein 1	0.265
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.265
WT1	Wilms tumor 1	0.235
ZNF512B	zinc finger protein 512B	0.232
FSTL1	follistatin-like 1	0.208
FZD1	frizzled homolog 1 (Drosophila)	0.206
SOX2	SRY (sex determining region Y)-box 2	0.205
CEP164	centrosomal protein 164kDa	0.194
SMAD1	SMAD family member 1	0.183
NCOA1	nuclear receptor coactivator 1	0.165
CTNND1	catenin (cadherin-associated protein), delta 1	0.141
NOSTRIN	nitric oxide synthase trafficker	0.138
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.127
LRRK2	leucine-rich repeat kinase 2	0.119
PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.115
SMAD7	SMAD family member 7	0.111
MDFI	MyoD family inhibitor	0.099
HTT	huntingtin	0.095
CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.094
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.093
FOXA1	forkhead box A1	0.092
ZFYVE9	zinc finger, FYVE domain containing 9	0.090
JUP	junction plakoglobin	0.090	Fly
NCOA6	nuclear receptor coactivator 6	0.071
FHL2	four and a half LIM domains 2	0.068
AR	androgen receptor	0.061	Mouse
HCFC1	host cell factor C1 (VP16-accessory protein)	0.059
GLIS2	GLIS family zinc finger 2	0.056
PSEN1	presenilin 1	0.054
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.053
FBXW11	F-box and WD repeat domain containing 11	0.052
ESR1	estrogen receptor 1	0.050
FGF7	fibroblast growth factor 7	0.049
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.049
TCF4	transcription factor 4	0.047
FAM110C	family with sequence similarity 110, member C	0.047
DSP	desmoplakin	0.046
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.046
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.045
PITX1	paired-like homeodomain 1	0.044
SOX10	SRY (sex determining region Y)-box 10	0.043
NOG	noggin	0.042
SPRY2	sprouty homolog 2 (Drosophila)	0.041
FERMT2	fermitin family member 2	0.040
BAHD1	bromo adjacent homology domain containing 1	0.039
HOXB9	homeobox B9	0.038
SHB	Src homology 2 domain containing adaptor protein B	0.037
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.036
FZD8	frizzled homolog 8 (Drosophila)	0.035
EYA1	eyes absent homolog 1 (Drosophila)	0.035
YAP1	Yes-associated protein 1	0.035
EYA2	eyes absent homolog 2 (Drosophila)	0.035
FRS2	fibroblast growth factor receptor substrate 2	0.034	Mouse
WDYHV1	WDYHV motif containing 1	0.034
LBX1	ladybird homeobox 1	0.034
FGF8	fibroblast growth factor 8 (androgen-induced)	0.033
HOXB5	homeobox B5	0.033
GAB1	GRB2-associated binding protein 1	0.033
BTRC	beta-transducin repeat containing	0.031
HOXD10	homeobox D10	0.031
FOXO3	forkhead box O3	0.031
DIDO1	death inducer-obliterator 1	0.030
BMP4	bone morphogenetic protein 4	0.030
ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	0.030
SOX11	SRY (sex determining region Y)-box 11	0.030
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.030
HOXC8	homeobox C8	0.030
MCC	mutated in colorectal cancers	0.030
C16orf48	chromosome 16 open reading frame 48	0.030
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.030
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.029
POU4F1	POU class 4 homeobox 1	0.028	Human
FGF4	fibroblast growth factor 4	0.028
OTP	orthopedia homeobox	0.028
NKX2-1	NK2 homeobox 1	0.027
SIX2	SIX homeobox 2	0.027
HOXD13	homeobox D13	0.027
NELL1	NEL-like 1 (chicken)	0.026
ZBTB8A	zinc finger and BTB domain containing 8A	0.026
DAXX	death-domain associated protein	0.025
PCBD1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	0.025
KAT2B	K(lysine) acetyltransferase 2B	0.024
ATN1	atrophin 1	0.024
PKP4	plakophilin 4	0.024
SOX1	SRY (sex determining region Y)-box 1	0.024
TP73	tumor protein p73	0.023
LHX1	LIM homeobox 1	0.023
SNIP1	Smad nuclear interacting protein 1	0.023
POU3F3	POU class 3 homeobox 3	0.023	Human
CDK11B	cyclin-dependent kinase 11B	0.023
CSNK1D	casein kinase 1, delta	0.023
SOX21	SRY (sex determining region Y)-box 21	0.023
MPZL1	myelin protein zero-like 1	0.023
MNX1	motor neuron and pancreas homeobox 1	0.023
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.022
KAL1	Kallmann syndrome 1 sequence	0.022
HOXC13	homeobox C13	0.022
BMPR1B	bone morphogenetic protein receptor, type IB	0.022
HOXC10	homeobox C10	0.022
EZR	ezrin	0.022
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.022
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.022
HOXB13	homeobox B13	0.022
HIC1	hypermethylated in cancer 1	0.022
HES1	hairy and enhancer of split 1, (Drosophila)	0.021
C9orf100	chromosome 9 open reading frame 100	0.021
CADM4	cell adhesion molecule 4	0.021
NEUROG3	neurogenin 3	0.021
FAM110A	family with sequence similarity 110, member A	0.021
GSK3B	glycogen synthase kinase 3 beta	0.021
DSG2	desmoglein 2	0.020
NKD2	naked cuticle homolog 2 (Drosophila)	0.020
ADARB1	adenosine deaminase, RNA-specific, B1	0.020
DLX4	distal-less homeobox 4	0.020
HOXD9	homeobox D9	0.020
HOXB7	homeobox B7	0.019
WNT3	wingless-type MMTV integration site family, member 3	0.019
ZNF408	zinc finger protein 408	0.019
TGFB2	transforming growth factor, beta 2	0.019
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.019
FOXL1	forkhead box L1	0.019
HOXC5	homeobox C5	0.019
PAX2	paired box 2	0.019
FGF10	fibroblast growth factor 10	0.019	Rat
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.019
FLNB	filamin B, beta	0.019
KLHL12	kelch-like 12 (Drosophila)	0.018
HOXA11	homeobox A11	0.018	Mouse
CBX8	chromobox homolog 8	0.018
HOXD3	homeobox D3	0.018
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.018
HOXB6	homeobox B6	0.018
HES2	hairy and enhancer of split 2 (Drosophila)	0.018
CDX2	caudal type homeobox 2	0.018
KAT5	K(lysine) acetyltransferase 5	0.018
JMJD1C	jumonji domain containing 1C	0.018
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.017
PAX6	paired box 6	0.017
ALX3	ALX homeobox 3	0.017
PITX2	paired-like homeodomain 2	0.017
DPPA4	developmental pluripotency associated 4	0.017
FZD2	frizzled homolog 2 (Drosophila)	0.017
TAOK1	TAO kinase 1	0.017
GATA5	GATA binding protein 5	0.017
SALL2	sal-like 2 (Drosophila)	0.017
MYOD1	myogenic differentiation 1	0.016
NCOA3	nuclear receptor coactivator 3	0.016
FGFR3	fibroblast growth factor receptor 3	0.016
NOVA2	neuro-oncological ventral antigen 2	0.016
CHERP	calcium homeostasis endoplasmic reticulum protein	0.016
GPRC5A	G protein-coupled receptor, family C, group 5, member A	0.016
TBX5	T-box 5	0.016
BMP2	bone morphogenetic protein 2	0.016
POU2F3	POU class 2 homeobox 3	0.016	Human
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.016
TNFAIP8L1	tumor necrosis factor, alpha-induced protein 8-like 1	0.016
MKL2	MKL/myocardin-like 2	0.016
RAX	retina and anterior neural fold homeobox	0.016
SIX1	SIX homeobox 1	0.016	Mouse
UTF1	undifferentiated embryonic cell transcription factor 1	0.016
SIX6	SIX homeobox 6	0.016
FBXL15	F-box and leucine-rich repeat protein 15	0.016
HOXC4	homeobox C4	0.016
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.015	Mouse
POU3F1	POU class 3 homeobox 1	0.015	Human
SMAD3	SMAD family member 3	0.015
ISL1	ISL LIM homeobox 1	0.015
PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	0.015
POU3F2	POU class 3 homeobox 2	0.015	Human
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.015
FGF3	fibroblast growth factor 3	0.015
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.015
ALX1	ALX homeobox 1	0.015
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.015
FOXA2	forkhead box A2	0.014
GMEB1	glucocorticoid modulatory element binding protein 1	0.014
PDX1	pancreatic and duodenal homeobox 1	0.014
WNT10A	wingless-type MMTV integration site family, member 10A	0.014
TIFA	TRAF-interacting protein with forkhead-associated domain	0.014
SIM2	single-minded homolog 2 (Drosophila)	0.014
OCLN	occludin	0.014
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.014
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.014
ZMYND8	zinc finger, MYND-type containing 8	0.014
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.014
DAAM1	dishevelled associated activator of morphogenesis 1	0.014
DMRT1	doublesex and mab-3 related transcription factor 1	0.014
GLI3	GLI family zinc finger 3	0.014
FOXD2	forkhead box D2	0.014
BDNF	brain-derived neurotrophic factor	0.013
FOXG1	forkhead box G1	0.013
SALL1	sal-like 1 (Drosophila)	0.013
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.013
THBS1	thrombospondin 1	0.013
BBS10	Bardet-Biedl syndrome 10	0.013
PRDM13	PR domain containing 13	0.013
FOXB1	forkhead box B1	0.013
ITGA7	integrin, alpha 7	0.013
ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19	0.013
HOXD11	homeobox D11	0.013	Mouse
RADIL	Ras association and DIL domains	0.013
MTF1	metal-regulatory transcription factor 1	0.013
IHH	Indian hedgehog	0.013
FAM46D	family with sequence similarity 46, member D	0.013
IL11	interleukin 11	0.013
HOXB8	homeobox B8	0.013
DPPA2	developmental pluripotency associated 2	0.013
EGR1	early growth response 1	0.013
PYY	peptide YY	0.013
PDLIM7	PDZ and LIM domain 7 (enigma)	0.013
NHLH2	nescient helix loop helix 2	0.013
PAX8	paired box 8	0.013
F3	coagulation factor III (thromboplastin, tissue factor)	0.013
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	0.013
SREBF2	sterol regulatory element binding transcription factor 2	0.013
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.013
SIM1	single-minded homolog 1 (Drosophila)	0.012
HOXB4	homeobox B4	0.012
BCL6	B-cell CLL/lymphoma 6	0.012
GAD1	glutamate decarboxylase 1 (brain, 67kDa)	0.012
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.012
COL2A1	collagen, type II, alpha 1	0.012
CCDC130	coiled-coil domain containing 130	0.012
XPC	xeroderma pigmentosum, complementation group C	0.012
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.012
GAL	galanin prepropeptide	0.012
DRD4	dopamine receptor D4	0.012
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.012
PTPRF	protein tyrosine phosphatase, receptor type, F	0.012
HDAC4	histone deacetylase 4	0.012
ZNF707	zinc finger protein 707	0.012
NCOA4	nuclear receptor coactivator 4	0.012
SRCAP	Snf2-related CREBBP activator protein	0.012
PKP2	plakophilin 2	0.012
PITX3	paired-like homeodomain 3	0.012
TLX2	T-cell leukemia homeobox 2	0.012
PTK7	PTK7 protein tyrosine kinase 7	0.012
SFRP5	secreted frizzled-related protein 5	0.012
POU4F2	POU class 4 homeobox 2	0.012	Human
GATA4	GATA binding protein 4	0.012
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.012
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.012
PGR	progesterone receptor	0.012
NCSTN	nicastrin	0.012
MSX2	msh homeobox 2	0.012
FOXF2	forkhead box F2	0.012
EN2	engrailed homeobox 2	0.012
TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	0.012
FGFR4	fibroblast growth factor receptor 4	0.012	Mouse
S1PR2	sphingosine-1-phosphate receptor 2	0.012
SIX3	SIX homeobox 3	0.012
FST	follistatin	0.012
IRS1	insulin receptor substrate 1	0.012
TNIK	TRAF2 and NCK interacting kinase	0.012
HOXC9	homeobox C9	0.011
HMGA2	high mobility group AT-hook 2	0.011
NKX2-8	NK2 homeobox 8	0.011
LHX5	LIM homeobox 5	0.011
LHCGR	luteinizing hormone/choriogonadotropin receptor	0.011
DIO3	deiodinase, iodothyronine, type III	0.011
HSD17B14	hydroxysteroid (17-beta) dehydrogenase 14	0.011
HOXC11	homeobox C11	0.011	Mouse
HOXA13	homeobox A13	0.011
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.011
SFRP1	secreted frizzled-related protein 1	0.011
TBX1	T-box 1	0.011
RET	ret proto-oncogene	0.011
OTX1	orthodenticle homeobox 1	0.011
KLF13	Kruppel-like factor 13	0.011
PAX5	paired box 5	0.011
LAT	linker for activation of T cells	0.011
PER1	period homolog 1 (Drosophila)	0.011
CAV1	caveolin 1, caveolae protein, 22kDa	0.011
TM4SF1	transmembrane 4 L six family member 1	0.011
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.011
BMP7	bone morphogenetic protein 7	0.011
CRLF1	cytokine receptor-like factor 1	0.011
NEUROG1	neurogenin 1	0.011
SETD1A	SET domain containing 1A	0.011
MYO1B	myosin IB	0.011
TCF7	transcription factor 7 (T-cell specific, HMG-box)	0.011
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.011
RORA	RAR-related orphan receptor A	0.011
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.011
ZNF496	zinc finger protein 496	0.011
PAX9	paired box 9	0.011
GSC2	goosecoid homeobox 2	0.011
COL4A6	collagen, type IV, alpha 6	0.011
FEV	FEV (ETS oncogene family)	0.011
KLB	klotho beta	0.011
BARX1	BARX homeobox 1	0.011
HOXD1	homeobox D1	0.011
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.011
NDP	Norrie disease (pseudoglioma)	0.011
HAND2	heart and neural crest derivatives expressed 2	0.011
GFRA1	GDNF family receptor alpha 1	0.011
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.011
L1TD1	LINE-1 type transposase domain containing 1	0.011
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.011
CUX1	cut-like homeobox 1	0.011
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.011
NKX3-2	NK3 homeobox 2	0.011
CST1	cystatin SN	0.011
GSX2	GS homeobox 2	0.011
IRF4	interferon regulatory factor 4	0.011
PAX3	paired box 3	0.011
EVX1	even-skipped homeobox 1	0.011
CALCR	calcitonin receptor	0.011
SALL4	sal-like 4 (Drosophila)	0.011
CCDC92	coiled-coil domain containing 92	0.011
SREBF1	sterol regulatory element binding transcription factor 1	0.010
SMAD6	SMAD family member 6	0.010
FGF19	fibroblast growth factor 19	0.010
NDUFA4L2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2	0.010
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.010
ONECUT2	one cut homeobox 2	0.010
WNT7A	wingless-type MMTV integration site family, member 7A	0.010
NKX2-2	NK2 homeobox 2	0.010
NKX2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.010
CBX2	chromobox homolog 2	0.010
NPAS3	neuronal PAS domain protein 3	0.010
HOXA2	homeobox A2	0.010
EPHA2	EPH receptor A2	0.010
FAM83B	family with sequence similarity 83, member B	0.010
ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)	0.010
ZNF165	zinc finger protein 165	0.010
MAST4	microtubule associated serine/threonine kinase family member 4	0.010
FZD10	frizzled homolog 10 (Drosophila)	0.010
HOXA10	homeobox A10	0.010
FHL3	four and a half LIM domains 3	0.010
HNF1B	HNF1 homeobox B	0.010
CTPS2	CTP synthase II	0.010
CCNO	cyclin O	0.010
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.010
NOS3	nitric oxide synthase 3 (endothelial cell)	0.010
MN1	meningioma (disrupted in balanced translocation) 1	0.010
VAX2	ventral anterior homeobox 2	0.010
PECAM1	platelet/endothelial cell adhesion molecule	0.010
HOXA3	homeobox A3	0.010
USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)	0.010
SHOX2	short stature homeobox 2	0.010
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.010