IMP: Integrative Multi-species Prediction

Homo sapiens

13 genes annotated in human

ribosomal small subunit biogenesis

A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ribosomal small subunit biogenesis"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "ribosomal small subunit biogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
RPS16	ribosomal protein S16	0.957
RPS3	ribosomal protein S3	0.935
WDR3	WD repeat domain 3	0.914	Yeast
RPS24	ribosomal protein S24	0.882
RPS5	ribosomal protein S5	0.843
NOLC1	nucleolar and coiled-body phosphoprotein 1	0.839
RPS23	ribosomal protein S23	0.812	Yeast
MKI67IP	MKI67 (FHA domain) interacting nucleolar phosphoprotein	0.782
CEBPZ	CCAAT/enhancer binding protein (C/EBP), zeta	0.770
POLR1C	polymerase (RNA) I polypeptide C, 30kDa	0.766
EIF3D	eukaryotic translation initiation factor 3, subunit D	0.765
RPS4X	ribosomal protein S4, X-linked	0.699
RPS6	ribosomal protein S6	0.699
RPS13	ribosomal protein S13	0.679	Yeast
PNO1	partner of NOB1 homolog (S. cerevisiae)	0.583	Yeast
GNL3	guanine nucleotide binding protein-like 3 (nucleolar)	0.577
RPS15A	ribosomal protein S15a	0.561
RPLP1	ribosomal protein, large, P1	0.527
MAK16	MAK16 homolog (S. cerevisiae)	0.428
WDR43	WD repeat domain 43	0.396	Yeast
ZC3H15	zinc finger CCCH-type containing 15	0.385
RPS28	ribosomal protein S28	0.384
RPL11	ribosomal protein L11	0.377
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.322
RPS25	ribosomal protein S25	0.309
RPS14	ribosomal protein S14	0.301
EIF3B	eukaryotic translation initiation factor 3, subunit B	0.300
UTP14A	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	0.290
NOC3L	nucleolar complex associated 3 homolog (S. cerevisiae)	0.275
RPS19	ribosomal protein S19	0.261
DDX21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	0.260
ESF1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	0.253
TGS1	trimethylguanosine synthase 1	0.244
DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	0.244	Yeast
CLNS1A	chloride channel, nucleotide-sensitive, 1A	0.239
RPS8	ribosomal protein S8	0.201	Yeast
FBL	fibrillarin	0.164
RPS10	ribosomal protein S10	0.162
RPS15	ribosomal protein S15	0.157
RRS1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	0.133
UTP3	UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)	0.132
RPS12	ribosomal protein S12	0.132
DIMT1L	DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)	0.126	Yeast
RPS18	ribosomal protein S18	0.121
DIEXF	digestive organ expansion factor homolog (zebrafish)	0.119	Yeast
ABCE1	ATP-binding cassette, sub-family E (OABP), member 1	0.117
RPS7	ribosomal protein S7	0.117
RIOK1	RIO kinase 1 (yeast)	0.112
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.111
RPS2	ribosomal protein S2	0.107
GTPBP4	GTP binding protein 4	0.105
RPS20	ribosomal protein S20	0.102	Yeast
IPO7	importin 7	0.101
ETF1	eukaryotic translation termination factor 1	0.097
LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.096
RPS17	ribosomal protein S17	0.094
RPS11	ribosomal protein S11	0.092	Yeast
ZNF593	zinc finger protein 593	0.091
HEATR1	HEAT repeat containing 1	0.088	Yeast Zebrafish
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.088
FTSJ3	FtsJ homolog 3 (E. coli)	0.082
RPS9	ribosomal protein S9	0.078	Yeast
RPS3A	ribosomal protein S3A	0.078	Yeast
PTRH2	peptidyl-tRNA hydrolase 2	0.078
EIF3A	eukaryotic translation initiation factor 3, subunit A	0.077
PITPNB	phosphatidylinositol transfer protein, beta	0.073
NAA38	N(alpha)-acetyltransferase 38, NatC auxiliary subunit	0.071
RPL5	ribosomal protein L5	0.070
NUFIP1	nuclear fragile X mental retardation protein interacting protein 1	0.070
UTP15	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)	0.070	Yeast
RPL36	ribosomal protein L36	0.069
C10orf2	chromosome 10 open reading frame 2	0.069
RPF2	ribosome production factor 2 homolog (S. cerevisiae)	0.069
RPL18	ribosomal protein L18	0.066
CCDC86	coiled-coil domain containing 86	0.063
RRP15	ribosomal RNA processing 15 homolog (S. cerevisiae)	0.062
NOC4L	nucleolar complex associated 4 homolog (S. cerevisiae)	0.061
WDR74	WD repeat domain 74	0.060
RPS27	ribosomal protein S27	0.055
RSL1D1	ribosomal L1 domain containing 1	0.055
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.055
AMD1	adenosylmethionine decarboxylase 1	0.054
PUS7	pseudouridylate synthase 7 homolog (S. cerevisiae)	0.054
RPL6	ribosomal protein L6	0.054
SART3	squamous cell carcinoma antigen recognized by T cells 3	0.053
RPSA	ribosomal protein SA	0.049	Yeast
CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)	0.047
RPL28	ribosomal protein L28	0.047
PAK1IP1	PAK1 interacting protein 1	0.045
WDR75	WD repeat domain 75	0.041
RPL23A	ribosomal protein L23a	0.040
EIF5B	eukaryotic translation initiation factor 5B	0.039	Yeast
LTV1	LTV1 homolog (S. cerevisiae)	0.038
DKC1	dyskeratosis congenita 1, dyskerin	0.037
RRP1B	ribosomal RNA processing 1 homolog B (S. cerevisiae)	0.033
RG9MTD1	RNA (guanine-9-) methyltransferase domain containing 1	0.032
RPLP0	ribosomal protein, large, P0	0.031
PRPF4	PRP4 pre-mRNA processing factor 4 homolog (yeast)	0.031
URB2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)	0.030
RRP9	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)	0.029
KIAA0020	KIAA0020	0.028
NOP14	NOP14 nucleolar protein homolog (yeast)	0.028	Yeast
RPL4	ribosomal protein L4	0.028
CCDC59	coiled-coil domain containing 59	0.028
DNTTIP2	deoxynucleotidyltransferase, terminal, interacting protein 2	0.027
MED1	mediator complex subunit 1	0.027
FAU	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	0.026
RPS21	ribosomal protein S21	0.026
DPH2	DPH2 homolog (S. cerevisiae)	0.026
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.025
TRMT1	TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)	0.025
RPL9	ribosomal protein L9	0.025
RPS29	ribosomal protein S29	0.024
RPL7	ribosomal protein L7	0.024
UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)	0.024
PWP1	PWP1 homolog (S. cerevisiae)	0.023
RIOK2	RIO kinase 2 (yeast)	0.023
NOP58	NOP58 ribonucleoprotein homolog (yeast)	0.023	Yeast
EIF3L	eukaryotic translation initiation factor 3, subunit L	0.022
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.022
RNASEH1	ribonuclease H1	0.022
GNL2	guanine nucleotide binding protein-like 2 (nucleolar)	0.020
RPLP2	ribosomal protein, large, P2	0.020
MTPAP	mitochondrial poly(A) polymerase	0.020
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.020
NOP2	NOP2 nucleolar protein homolog (yeast)	0.019
RPL19	ribosomal protein L19	0.019
EIF2S2	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	0.019
CCDC47	coiled-coil domain containing 47	0.018
NOL8	nucleolar protein 8	0.018
MPHOSPH10	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)	0.017	Yeast
EPRS	glutamyl-prolyl-tRNA synthetase	0.017
BYSL	bystin-like	0.017	Yeast Mouse
FARSA	phenylalanyl-tRNA synthetase, alpha subunit	0.016
MINA	MYC induced nuclear antigen	0.016
TWISTNB	TWIST neighbor	0.016
BRIX1	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)	0.015
RPL27A	ribosomal protein L27a	0.015
NIP7	nuclear import 7 homolog (S. cerevisiae)	0.015
ARRB2	arrestin, beta 2	0.014
OGFOD1	2-oxoglutarate and iron-dependent oxygenase domain containing 1	0.014
PPRC1	peroxisome proliferator-activated receptor gamma, coactivator-related 1	0.013
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.013
CEBPE	CCAAT/enhancer binding protein (C/EBP), epsilon	0.013
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.012
USP10	ubiquitin specific peptidase 10	0.012
ZNF259	zinc finger protein 259	0.012
LSG1	large subunit GTPase 1 homolog (S. cerevisiae)	0.012
RPL23	ribosomal protein L23	0.012
PUS3	pseudouridylate synthase 3	0.012
DDX54	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	0.012
EEF2	eukaryotic translation elongation factor 2	0.012
NKRF	NFKB repressing factor	0.011
C8orf33	chromosome 8 open reading frame 33	0.011
NSUN2	NOP2/Sun domain family, member 2	0.011
RPL27	ribosomal protein L27	0.011
TXLNG	taxilin gamma	0.011
RPL12	ribosomal protein L12	0.011
GSPT1	G1 to S phase transition 1	0.011
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.010
AATF	apoptosis antagonizing transcription factor	0.010
LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.010
CSNK1E	casein kinase 1, epsilon	0.010	Yeast