IMP
Process View
skin morphogenesis
The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "skin morphogenesis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| KRT17 | keratin 17 | 0.925 | ||
| COL1A1 | collagen, type I, alpha 1 | 0.842 | ||
| KLK7 | kallikrein-related peptidase 7 | 0.791 | Human | |
| TP63 | tumor protein p63 | 0.742 | Zebrafish Mouse | |
| SFN | stratifin | 0.681 | ||
| KRT15 | keratin 15 | 0.642 | ||
| KLK10 | kallikrein-related peptidase 10 | 0.541 | Human | |
| KRT5 | keratin 5 | 0.534 | Human | |
| TRIM29 | tripartite motif containing 29 | 0.481 | ||
| KRT14 | keratin 14 | 0.440 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.427 | ||
| KRT6A | keratin 6A | 0.417 | Human | |
| KRT6B | keratin 6B | 0.324 | Human | |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.287 | ||
| COL1A2 | collagen, type I, alpha 2 | 0.274 | ||
| KLK5 | kallikrein-related peptidase 5 | 0.214 | Human | |
| KRT6C | keratin 6C | 0.204 | Human | |
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.204 | Worm Fly | |
| PDZD11 | PDZ domain containing 11 | 0.201 | ||
| KRT19 | keratin 19 | 0.191 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.189 | ||
| NOTCH3 | notch 3 | 0.184 | ||
| COL5A2 | collagen, type V, alpha 2 | 0.167 | Human | |
| IVL | involucrin | 0.159 | ||
| PKP1 | plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | 0.158 | ||
| FGF1 | fibroblast growth factor 1 (acidic) | 0.137 | ||
| JAG1 | jagged 1 | 0.116 | ||
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.112 | Fly | |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.111 | ||
| GJB3 | gap junction protein, beta 3, 31kDa | 0.106 | ||
| PRSS2 | protease, serine, 2 (trypsin 2) | 0.095 | ||
| LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.091 | ||
| BCL2L1 | BCL2-like 1 | 0.088 | ||
| COL3A1 | collagen, type III, alpha 1 | 0.074 | Human | |
| KRT16 | keratin 16 | 0.072 | ||
| FN1 | fibronectin 1 | 0.072 | ||
| COL6A1 | collagen, type VI, alpha 1 | 0.070 | ||
| FGF2 | fibroblast growth factor 2 (basic) | 0.067 | ||
| SPRR1B | small proline-rich protein 1B | 0.065 | ||
| FHL2 | four and a half LIM domains 2 | 0.061 | ||
| AR | androgen receptor | 0.061 | ||
| PKP3 | plakophilin 3 | 0.061 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.060 | ||
| LAD1 | ladinin 1 | 0.058 | ||
| BAD | BCL2-associated agonist of cell death | 0.052 | ||
| LYPD3 | LY6/PLAUR domain containing 3 | 0.050 | ||
| ALB | albumin | 0.050 | ||
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.049 | ||
| KRT18 | keratin 18 | 0.049 | ||
| JUB | jub, ajuba homolog (Xenopus laevis) | 0.042 | ||
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.038 | ||
| COL4A1 | collagen, type IV, alpha 1 | 0.034 | ||
| KLK11 | kallikrein-related peptidase 11 | 0.033 | Human | |
| DSG3 | desmoglein 3 | 0.033 | ||
| COL5A1 | collagen, type V, alpha 1 | 0.032 | Human | |
| FLNB | filamin B, beta | 0.030 | ||
| ADAM12 | ADAM metallopeptidase domain 12 | 0.029 | ||
| PPL | periplakin | 0.026 | ||
| SPRR1A | small proline-rich protein 1A | 0.026 | ||
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.025 | ||
| GJB5 | gap junction protein, beta 5, 31.1kDa | 0.025 | ||
| SLURP1 | secreted LY6/PLAUR domain containing 1 | 0.024 | ||
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | 0.024 | ||
| S100A2 | S100 calcium binding protein A2 | 0.023 | ||
| KLK8 | kallikrein-related peptidase 8 | 0.022 | Human | |
| MKL1 | megakaryoblastic leukemia (translocation) 1 | 0.022 | ||
| FGF10 | fibroblast growth factor 10 | 0.022 | ||
| KRT9 | keratin 9 | 0.021 | ||
| FGFR3 | fibroblast growth factor receptor 3 | 0.020 | ||
| CSNK1E | casein kinase 1, epsilon | 0.020 | ||
| KRT13 | keratin 13 | 0.020 | ||
| EVPL | envoplakin | 0.019 | ||
| LY6D | lymphocyte antigen 6 complex, locus D | 0.019 | ||
| EP300 | E1A binding protein p300 | 0.019 | ||
| KRT1 | keratin 1 | 0.018 | Human | |
| AXIN1 | axin 1 | 0.018 | ||
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.017 | ||
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.017 | ||
| KRT34 | keratin 34 | 0.017 | ||
| ATN1 | atrophin 1 | 0.016 | ||
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | 0.016 | ||
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.015 | ||
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.015 | ||
| SH3BP4 | SH3-domain binding protein 4 | 0.015 | ||
| POSTN | periostin, osteoblast specific factor | 0.014 | ||
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.014 | ||
| KLK12 | kallikrein-related peptidase 12 | 0.014 | Human | |
| MXRA5 | matrix-remodelling associated 5 | 0.014 | ||
| KLK6 | kallikrein-related peptidase 6 | 0.013 | Human | |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.013 | ||
| TNS4 | tensin 4 | 0.013 | ||
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.013 | ||
| DSG1 | desmoglein 1 | 0.012 | ||
| LY6G6C | lymphocyte antigen 6 complex, locus G6C | 0.012 | ||
| CDSN | corneodesmosin | 0.012 | ||
| RHOD | ras homolog gene family, member D | 0.012 | ||
| KRT75 | keratin 75 | 0.012 | Human | |
| MYOCD | myocardin | 0.012 | ||
| KRT81 | keratin 81 | 0.012 | Human | |
| S100A14 | S100 calcium binding protein A14 | 0.012 | ||
| CTGF | connective tissue growth factor | 0.011 | ||
| EPS8L1 | EPS8-like 1 | 0.011 | Worm | |
| PI3 | peptidase inhibitor 3, skin-derived | 0.011 | ||
| SP1 | Sp1 transcription factor | 0.011 | ||
| KRT33B | keratin 33B | 0.011 | ||
| PITX1 | paired-like homeodomain 1 | 0.010 | ||
| COL17A1 | collagen, type XVII, alpha 1 | 0.010 |