Homo sapiens

2 genes annotated in human

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mature dendritic cell differentiation

GO:0097029

The process in which antigen-activated dendritic cells acquire the specialized features of a mature dendritic cell. Mature dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.

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