IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

histone exchange

The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "histone exchange"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "histone exchange" (in gray)

Name	Description	Probability	Func Analog Organism
RUVBL1	RuvB-like 1 (E. coli)	1.000
YY1	YY1 transcription factor	0.999
ACTL6A	actin-like 6A	0.999
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.985
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.903
DPCD	deleted in primary ciliary dyskinesia homolog (mouse)	0.866
C20orf20	chromosome 20 open reading frame 20	0.839
VPS72	vacuolar protein sorting 72 homolog (S. cerevisiae)	0.806
MRFAP1	Morf4 family associated protein 1	0.712
INO80E	INO80 complex subunit E	0.625
BAZ1A	bromodomain adjacent to zinc finger domain, 1A	0.585
INO80	INO80 homolog (S. cerevisiae)	0.557	Yeast
ACTR5	ARP5 actin-related protein 5 homolog (yeast)	0.510
TRRAP	transformation/transcription domain-associated protein	0.462	Fly
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.405
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.392
MORF4L2	mortality factor 4 like 2	0.389	Fly
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	0.249
CHAF1B	chromatin assembly factor 1, subunit B (p60)	0.247
CDAN1	congenital dyserythropoietic anemia, type I	0.245
TLK1	tousled-like kinase 1	0.242
ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.231	Human
SET	SET nuclear oncogene	0.203
CHRAC1	chromatin accessibility complex 1	0.174
HDAC2	histone deacetylase 2	0.142
MRFAP1L1	Morf4 family associated protein 1-like 1	0.140
CENPA	centromere protein A	0.140
HMGB2	high mobility group box 2	0.138
NUP153	nucleoporin 153kDa	0.126
RPA1	replication protein A1, 70kDa	0.123
CDR2	cerebellar degeneration-related protein 2, 62kDa	0.107
ACTR8	ARP8 actin-related protein 8 homolog (yeast)	0.106
TTI1	Tel2 interacting protein 1 homolog (S. pombe)	0.106
KAT2A	K(lysine) acetyltransferase 2A	0.100
POLE	polymerase (DNA directed), epsilon	0.099
EP400	E1A binding protein p400	0.092	Fly
CBX5	chromobox homolog 5	0.090
PIH1D1	PIH1 domain containing 1	0.089
MSH6	mutS homolog 6 (E. coli)	0.078
NFRKB	nuclear factor related to kappaB binding protein	0.077
INO80D	INO80 complex subunit D	0.057
DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.056
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.055
PTMA	prothymosin, alpha	0.054
ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.053	Yeast
MORF4L1	mortality factor 4 like 1	0.053	Fly
NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.053
INO80C	INO80 complex subunit C	0.053
TOP2B	topoisomerase (DNA) II beta 180kDa	0.052
KAT5	K(lysine) acetyltransferase 5	0.049
BCLAF1	BCL2-associated transcription factor 1	0.048
POLE4	polymerase (DNA-directed), epsilon 4 (p12 subunit)	0.047
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.044
ATXN7	ataxin 7	0.043
HMGB1	high mobility group box 1	0.042
DEK	DEK oncogene	0.042
DMAP1	DNA methyltransferase 1 associated protein 1	0.041	Yeast
H2AFV	H2A histone family, member V	0.040
USP1	ubiquitin specific peptidase 1	0.039
RAD21	RAD21 homolog (S. pombe)	0.037
ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	0.037	Human
SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0.036	Yeast
SLBP	stem-loop binding protein	0.035
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.035
CREB1	cAMP responsive element binding protein 1	0.034
INO80B	INO80 complex subunit B	0.034
RSF1	remodeling and spacing factor 1	0.033
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.032
RUVBL2	RuvB-like 2 (E. coli)	0.032	Yeast
H2AFZ	H2A histone family, member Z	0.031
FBL	fibrillarin	0.030
DUT	deoxyuridine triphosphatase	0.030
YAF2	YY1 associated factor 2	0.029
RRM1	ribonucleotide reductase M1	0.029
PRMT1	protein arginine methyltransferase 1	0.028
PPIH	peptidylprolyl isomerase H (cyclophilin H)	0.028
HMGN2	high mobility group nucleosomal binding domain 2	0.028
MAX	MYC associated factor X	0.027
FOXM1	forkhead box M1	0.027
FBXW7	F-box and WD repeat domain containing 7	0.025
MCRS1	microspherule protein 1	0.025
ACTR6	ARP6 actin-related protein 6 homolog (yeast)	0.025
PRRC2C	proline-rich coiled-coil 2C	0.024
TLK2	tousled-like kinase 2	0.023
ZNF267	zinc finger protein 267	0.023
TOP1	topoisomerase (DNA) I	0.022
SUMO4	SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)	0.022
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.022	Mouse
PSIP1	PC4 and SFRS1 interacting protein 1	0.022
CBX1	chromobox homolog 1	0.021
UBN1	ubinuclein 1	0.021
FDFT1	farnesyl-diphosphate farnesyltransferase 1	0.021
BIN1	bridging integrator 1	0.021
KPNA6	karyopherin alpha 6 (importin alpha 7)	0.021
PRPS1	phosphoribosyl pyrophosphate synthetase 1	0.020
TFPT	TCF3 (E2A) fusion partner (in childhood Leukemia)	0.020
RBBP4	retinoblastoma binding protein 4	0.020
NRIP1	nuclear receptor interacting protein 1	0.020
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.020
SRP9	signal recognition particle 9kDa	0.019
SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.019
PTK2	PTK2 protein tyrosine kinase 2	0.019
CNN3	calponin 3, acidic	0.019
NUPL1	nucleoporin like 1	0.019
UCHL5	ubiquitin carboxyl-terminal hydrolase L5	0.019
UBTF	upstream binding transcription factor, RNA polymerase I	0.019
GSG2	germ cell associated 2 (haspin)	0.018
APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1	0.018
IPO4	importin 4	0.018
GMPS	guanine monphosphate synthetase	0.017
SMNDC1	survival motor neuron domain containing 1	0.017
SMCHD1	structural maintenance of chromosomes flexible hinge domain containing 1	0.017
TMX1	thioredoxin-related transmembrane protein 1	0.017
AXIN1	axin 1	0.017
CBX3	chromobox homolog 3	0.017
DDB1	damage-specific DNA binding protein 1, 127kDa	0.016
DNTTIP2	deoxynucleotidyltransferase, terminal, interacting protein 2	0.016
FBXW8	F-box and WD repeat domain containing 8	0.016
C10orf18	chromosome 10 open reading frame 18	0.016
KPNB1	karyopherin (importin) beta 1	0.016
BLMH	bleomycin hydrolase	0.016
BRD8	bromodomain containing 8	0.016
ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	0.016
ZNHIT1	zinc finger, HIT-type containing 1	0.016
TAF1A	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa	0.015
USP22	ubiquitin specific peptidase 22	0.015
HIST1H3B	histone cluster 1, H3b	0.015
ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	0.015
C9orf78	chromosome 9 open reading frame 78	0.015
RPA2	replication protein A2, 32kDa	0.015
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.015
TERT	telomerase reverse transcriptase	0.014
RBMX	RNA binding motif protein, X-linked	0.014
TMEM14B	transmembrane protein 14B	0.014
NONO	non-POU domain containing, octamer-binding	0.014
TRIP12	thyroid hormone receptor interactor 12	0.014
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.014
DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	0.013
PPP2R2D	protein phosphatase 2, regulatory subunit B, delta	0.013
GTF2A2	general transcription factor IIA, 2, 12kDa	0.013
SSRP1	structure specific recognition protein 1	0.013
ANKRD17	ankyrin repeat domain 17	0.013
KIF4A	kinesin family member 4A	0.013
E2F7	E2F transcription factor 7	0.013
SMAD2	SMAD family member 2	0.012
SEC24A	SEC24 family, member A (S. cerevisiae)	0.012
HDAC1	histone deacetylase 1	0.012
WHSC1	Wolf-Hirschhorn syndrome candidate 1	0.012
PCNT	pericentrin	0.012
POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.012
FAM64A	family with sequence similarity 64, member A	0.012
CNOT1	CCR4-NOT transcription complex, subunit 1	0.012
RPIA	ribose 5-phosphate isomerase A	0.012
PCNA	proliferating cell nuclear antigen	0.012
CTCF	CCCTC-binding factor (zinc finger protein)	0.012
NCAPD2	non-SMC condensin I complex, subunit D2	0.012
HIRIP3	HIRA interacting protein 3	0.012
TUBA1B	tubulin, alpha 1b	0.011
SAP30	Sin3A-associated protein, 30kDa	0.011
HMGN1	high mobility group nucleosome binding domain 1	0.011
ARHGAP19	Rho GTPase activating protein 19	0.011
FAM193A	family with sequence similarity 193, member A	0.011
IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2	0.011
FAM98A	family with sequence similarity 98, member A	0.011
RBM15	RNA binding motif protein 15	0.011
SMC4	structural maintenance of chromosomes 4	0.011
CDYL	chromodomain protein, Y-like	0.011
PBRM1	polybromo 1	0.011
CHD4	chromodomain helicase DNA binding protein 4	0.011
NAF1	nuclear assembly factor 1 homolog (S. cerevisiae)	0.011
ZBTB17	zinc finger and BTB domain containing 17	0.011
TOPORS	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	0.011
GOLGA3	golgin A3	0.011
SMC5	structural maintenance of chromosomes 5	0.010
BRCA2	breast cancer 2, early onset	0.010
HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)	0.010	Fly
AHCTF1	AT hook containing transcription factor 1	0.010
C1orf9	chromosome 1 open reading frame 9	0.010
TDG	thymine-DNA glycosylase	0.010
E2F2	E2F transcription factor 2	0.010
TAF10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	0.010
SSFA2	sperm specific antigen 2	0.010