IMP
Process View
toll signaling pathway
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "toll signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.632 | ||
| PELP1 | proline, glutamate and leucine rich protein 1 | 0.599 | ||
| USPL1 | ubiquitin specific peptidase like 1 | 0.461 | ||
| ZNF496 | zinc finger protein 496 | 0.302 | ||
| RANGAP1 | Ran GTPase activating protein 1 | 0.228 | ||
| ELK1 | ELK1, member of ETS oncogene family | 0.106 | ||
| SUMO3 | SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) | 0.099 | ||
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.096 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.088 | ||
| CHMP4B | chromatin modifying protein 4B | 0.075 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.065 | ||
| DAXX | death-domain associated protein | 0.063 | ||
| TSG101 | tumor susceptibility gene 101 | 0.054 | ||
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.045 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.042 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.037 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.034 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.033 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.032 | Fly | |
| MDN1 | MDN1, midasin homolog (yeast) | 0.030 | ||
| SH3GL2 | SH3-domain GRB2-like 2 | 0.026 | ||
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 | 0.024 | ||
| TLR4 | toll-like receptor 4 | 0.022 | ||
| SAE1 | SUMO1 activating enzyme subunit 1 | 0.022 | ||
| IRAK4 | interleukin-1 receptor-associated kinase 4 | 0.021 | ||
| SUMO1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.021 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.021 | ||
| PTPN23 | protein tyrosine phosphatase, non-receptor type 23 | 0.020 | Fly | |
| ZMYM2 | zinc finger, MYM-type 2 | 0.019 | ||
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.019 | ||
| NKTR | natural killer-tumor recognition sequence | 0.018 | ||
| SUMO2 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) | 0.018 | ||
| TLR2 | toll-like receptor 2 | 0.017 | ||
| GRAP2 | GRB2-related adaptor protein 2 | 0.017 | ||
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | 0.016 | ||
| TRAF3 | TNF receptor-associated factor 3 | 0.016 | ||
| SF3B4 | splicing factor 3b, subunit 4, 49kDa | 0.016 | ||
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.016 | ||
| MEN1 | multiple endocrine neoplasia I | 0.016 | ||
| IRF7 | interferon regulatory factor 7 | 0.015 | ||
| SP100 | SP100 nuclear antigen | 0.015 | ||
| FNBP4 | formin binding protein 4 | 0.015 | ||
| PDCD6 | programmed cell death 6 | 0.014 | ||
| WRN | Werner syndrome, RecQ helicase-like | 0.014 | ||
| TRIM27 | tripartite motif containing 27 | 0.014 | ||
| PELI1 | pellino homolog 1 (Drosophila) | 0.014 | ||
| PYCARD | PYD and CARD domain containing | 0.014 | ||
| PYDC2 | pyrin domain containing 2 | 0.013 | ||
| OFD1 | oral-facial-digital syndrome 1 | 0.013 | ||
| MEF2A | myocyte enhancer factor 2A | 0.013 | ||
| NLRC4 | NLR family, CARD domain containing 4 | 0.012 | ||
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.012 | Fly | |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.012 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.012 | ||
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.012 | ||
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.011 | ||
| WDR33 | WD repeat domain 33 | 0.011 | ||
| IKZF3 | IKAROS family zinc finger 3 (Aiolos) | 0.011 | ||
| GNMT | glycine N-methyltransferase | 0.011 | ||
| PAN3 | PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) | 0.011 | ||
| TDG | thymine-DNA glycosylase | 0.011 | ||
| SUMO4 | SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae) | 0.011 | ||
| PIAS3 | protein inhibitor of activated STAT, 3 | 0.011 | ||
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.011 | ||
| MBD1 | methyl-CpG binding domain protein 1 | 0.010 | ||
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.010 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.010 | ||
| KIAA0907 | KIAA0907 | 0.010 | ||
| SAMHD1 | SAM domain and HD domain 1 | 0.010 |