IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

maturation of lsu rrna

Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "maturation of lsu rrna"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "maturation of lsu rrna" (in gray)

Name	Description	Probability	Func Analog Organism
LYAR	Ly1 antibody reactive homolog (mouse)	0.991
MYBBP1A	MYB binding protein (P160) 1a	0.861
GNL3	guanine nucleotide binding protein-like 3 (nucleolar)	0.855
NOP56	NOP56 ribonucleoprotein homolog (yeast)	0.750
PPRC1	peroxisome proliferator-activated receptor gamma, coactivator-related 1	0.649
NOP2	NOP2 nucleolar protein homolog (yeast)	0.611	Yeast
C10orf2	chromosome 10 open reading frame 2	0.534
PUS1	pseudouridylate synthase 1	0.513
PPAN	peter pan homolog (Drosophila)	0.443	Yeast
PAK1IP1	PAK1 interacting protein 1	0.425	Yeast
PDCD11	programmed cell death 11	0.418	Yeast
DKC1	dyskeratosis congenita 1, dyskerin	0.403
RBM28	RNA binding motif protein 28	0.387	Yeast
EEF1B2	eukaryotic translation elongation factor 1 beta 2	0.375
RRS1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	0.375
WDR3	WD repeat domain 3	0.337
NOC3L	nucleolar complex associated 3 homolog (S. cerevisiae)	0.334
BOP1	block of proliferation 1	0.326
GNL2	guanine nucleotide binding protein-like 2 (nucleolar)	0.269
IPO4	importin 4	0.267
PES1	pescadillo homolog 1, containing BRCT domain (zebrafish)	0.245
NOP58	NOP58 ribonucleoprotein homolog (yeast)	0.241
WDR75	WD repeat domain 75	0.218
TRMT1	TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)	0.213
PUS7	pseudouridylate synthase 7 homolog (S. cerevisiae)	0.189
NOL8	nucleolar protein 8	0.189
NOLC1	nucleolar and coiled-body phosphoprotein 1	0.147
NSUN2	NOP2/Sun domain family, member 2	0.141
ABCE1	ATP-binding cassette, sub-family E (OABP), member 1	0.126
WDR74	WD repeat domain 74	0.121
RRP9	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)	0.121
DHX37	DEAH (Asp-Glu-Ala-His) box polypeptide 37	0.120
CEBPZ	CCAAT/enhancer binding protein (C/EBP), zeta	0.109
NOL11	nucleolar protein 11	0.098
HEATR1	HEAT repeat containing 1	0.098
DDX21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	0.096
WDR43	WD repeat domain 43	0.089
KIAA0020	KIAA0020	0.083
GTPBP4	GTP binding protein 4	0.078
RPL29	ribosomal protein L29	0.077
U2SURP	U2 snRNP-associated SURP domain containing	0.075
DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	0.073	Yeast
UTP14A	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	0.071
BMS1	BMS1 homolog, ribosome assembly protein (yeast)	0.067
DDX47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47	0.062
NOP14	NOP14 nucleolar protein homolog (yeast)	0.060
RIOK1	RIO kinase 1 (yeast)	0.056
TIMM9	translocase of inner mitochondrial membrane 9 homolog (yeast)	0.056
DIEXF	digestive organ expansion factor homolog (zebrafish)	0.055
DPH2	DPH2 homolog (S. cerevisiae)	0.055
NAT10	N-acetyltransferase 10 (GCN5-related)	0.054
FTSJ3	FtsJ homolog 3 (E. coli)	0.052
PINX1	PIN2/TERF1 interacting, telomerase inhibitor 1	0.052
EIF3H	eukaryotic translation initiation factor 3, subunit H	0.052
WDR12	WD repeat domain 12	0.049
MAK16	MAK16 homolog (S. cerevisiae)	0.048
MPHOSPH10	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)	0.048
PTRH2	peptidyl-tRNA hydrolase 2	0.046
GAR1	GAR1 ribonucleoprotein homolog (yeast)	0.045
SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	0.045
TSR1	TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)	0.044
ATAD3A	ATPase family, AAA domain containing 3A	0.044
NOC2L	nucleolar complex associated 2 homolog (S. cerevisiae)	0.043
RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)	0.043
URB2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)	0.043
NUFIP1	nuclear fragile X mental retardation protein interacting protein 1	0.042
PWP1	PWP1 homolog (S. cerevisiae)	0.042
EIF3B	eukaryotic translation initiation factor 3, subunit B	0.041
UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)	0.040
EIF5B	eukaryotic translation initiation factor 5B	0.040
ESF1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	0.039
C12orf11	chromosome 12 open reading frame 11	0.039
WDR46	WD repeat domain 46	0.038
SENP3	SUMO1/sentrin/SMT3 specific peptidase 3	0.037
ABCF2	ATP-binding cassette, sub-family F (GCN20), member 2	0.037
TRMU	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase	0.037
DDX27	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	0.035
RRP15	ribosomal RNA processing 15 homolog (S. cerevisiae)	0.035
PELP1	proline, glutamate and leucine rich protein 1	0.035
ASCC3	activating signal cointegrator 1 complex subunit 3	0.033
DDX10	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10	0.033
UTP3	UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)	0.032
UBA52	ubiquitin A-52 residue ribosomal protein fusion product 1	0.032
DDX31	DEAD (Asp-Glu-Ala-Asp) box polypeptide 31	0.031	Yeast
LAS1L	LAS1-like (S. cerevisiae)	0.031
CUL1	cullin 1	0.030
TDG	thymine-DNA glycosylase	0.029
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.029
OTUD6B	OTU domain containing 6B	0.028
ZC3H15	zinc finger CCCH-type containing 15	0.028
RPL36	ribosomal protein L36	0.028
GCN1L1	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	0.028
NOM1	nucleolar protein with MIF4G domain 1	0.028
TTC27	tetratricopeptide repeat domain 27	0.028
BRIX1	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)	0.027
AMD1	adenosylmethionine decarboxylase 1	0.027
RPL4	ribosomal protein L4	0.027
METTL1	methyltransferase like 1	0.027
NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	0.026
GRWD1	glutamate-rich WD repeat containing 1	0.026
DNTTIP2	deoxynucleotidyltransferase, terminal, interacting protein 2	0.026
PWP2	PWP2 periodic tryptophan protein homolog (yeast)	0.025
DNAJC2	DnaJ (Hsp40) homolog, subfamily C, member 2	0.025
NDUFAF2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2	0.025
NUP35	nucleoporin 35kDa	0.025
GEMIN4	gem (nuclear organelle) associated protein 4	0.024
ADAT2	adenosine deaminase, tRNA-specific 2, TAD2 homolog (S. cerevisiae)	0.024
SSB	Sjogren syndrome antigen B (autoantigen La)	0.024
MRTO4	mRNA turnover 4 homolog (S. cerevisiae)	0.024
POLR3G	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	0.024
POLR1C	polymerase (RNA) I polypeptide C, 30kDa	0.023
NOC4L	nucleolar complex associated 4 homolog (S. cerevisiae)	0.023
RPL35A	ribosomal protein L35a	0.022
SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)	0.022
UTP6	UTP6, small subunit (SSU) processome component, homolog (yeast)	0.022
PPAT	phosphoribosyl pyrophosphate amidotransferase	0.022
RPS10	ribosomal protein S10	0.021
BCS1L	BCS1-like (S. cerevisiae)	0.021
NOL6	nucleolar protein family 6 (RNA-associated)	0.020
MTPAP	mitochondrial poly(A) polymerase	0.020
RPS3	ribosomal protein S3	0.019
PITPNB	phosphatidylinositol transfer protein, beta	0.019
SURF6	surfeit 6	0.019
POLR1D	polymerase (RNA) I polypeptide D, 16kDa	0.018
MINA	MYC induced nuclear antigen	0.018
RPL17	ribosomal protein L17	0.018
RPS19	ribosomal protein S19	0.018
KIAA0664	KIAA0664	0.018
NLE1	notchless homolog 1 (Drosophila)	0.018
CHMP7	CHMP family, member 7	0.017
UBIAD1	UbiA prenyltransferase domain containing 1	0.017
PNPT1	polyribonucleotide nucleotidyltransferase 1	0.017
NCL	nucleolin	0.017
TMEM126B	transmembrane protein 126B	0.017
RPS16	ribosomal protein S16	0.017
SPATA5L1	spermatogenesis associated 5-like 1	0.017
DDX56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56	0.017	Yeast
RBM17	RNA binding motif protein 17	0.017
EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	0.016
C16orf88	chromosome 16 open reading frame 88	0.016
SELRC1	Sel1 repeat containing 1	0.016
C12orf45	chromosome 12 open reading frame 45	0.016
RSL1D1	ribosomal L1 domain containing 1	0.016
RPL38	ribosomal protein L38	0.016
TGS1	trimethylguanosine synthase 1	0.016
GART	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	0.016
PAFAH1B2	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)	0.016
HEATR3	HEAT repeat containing 3	0.016
POLR1E	polymerase (RNA) I polypeptide E, 53kDa	0.015
RPL36AL	ribosomal protein L36a-like	0.015
PFAS	phosphoribosylformylglycinamidine synthase	0.015
DDX55	DEAD (Asp-Glu-Ala-Asp) box polypeptide 55	0.015	Yeast
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.015
NACA	nascent polypeptide-associated complex alpha subunit	0.015
ARMC6	armadillo repeat containing 6	0.015
TXLNG	taxilin gamma	0.014
LTV1	LTV1 homolog (S. cerevisiae)	0.014
MRPS5	mitochondrial ribosomal protein S5	0.014
TRMT6	tRNA methyltransferase 6 homolog (S. cerevisiae)	0.014
CTPS	CTP synthase	0.013
NKRF	NFKB repressing factor	0.013
TBL3	transducin (beta)-like 3	0.013
EED	embryonic ectoderm development	0.013
BRD9	bromodomain containing 9	0.013
RPL21	ribosomal protein L21	0.013
SDCCAG3	serologically defined colon cancer antigen 3	0.013
ZNF202	zinc finger protein 202	0.013
TEAD4	TEA domain family member 4	0.013
PAM16	presequence translocase-associated motor 16 homolog (S. cerevisiae)	0.013
TFAM	transcription factor A, mitochondrial	0.013
TIMM44	translocase of inner mitochondrial membrane 44 homolog (yeast)	0.012
TAF1A	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa	0.012
QTRTD1	queuine tRNA-ribosyltransferase domain containing 1	0.012
RRP1B	ribosomal RNA processing 1 homolog B (S. cerevisiae)	0.012
DHX33	DEAH (Asp-Glu-Ala-His) box polypeptide 33	0.012
RPS26	ribosomal protein S26	0.012
RPS5	ribosomal protein S5	0.012
RPL26	ribosomal protein L26	0.012
CLNS1A	chloride channel, nucleotide-sensitive, 1A	0.012
TOMM40	translocase of outer mitochondrial membrane 40 homolog (yeast)	0.012
BAZ1A	bromodomain adjacent to zinc finger domain, 1A	0.011
AGPAT5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)	0.011
RARS	arginyl-tRNA synthetase	0.011
PGM2	phosphoglucomutase 2	0.011
CUL4A	cullin 4A	0.011
RPL36A	ribosomal protein L36a	0.011
DIMT1L	DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)	0.011
MCMBP	minichromosome maintenance complex binding protein	0.011
TAF1B	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	0.011
PIGW	phosphatidylinositol glycan anchor biosynthesis, class W	0.011
FASTKD1	FAST kinase domains 1	0.011
RRP1	ribosomal RNA processing 1 homolog (S. cerevisiae)	0.011
SUGP1	SURP and G patch domain containing 1	0.011
RPL14	ribosomal protein L14	0.011
RRP7A	ribosomal RNA processing 7 homolog A (S. cerevisiae)	0.011
ZNHIT6	zinc finger, HIT-type containing 6	0.011
EVL	Enah/Vasp-like	0.011
NUS1	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	0.011
REXO4	REX4, RNA exonuclease 4 homolog (S. cerevisiae)	0.011
METTL8	methyltransferase like 8	0.010
METAP2	methionyl aminopeptidase 2	0.010
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.010
RPL24	ribosomal protein L24	0.010
RPS7	ribosomal protein S7	0.010
BYSL	bystin-like	0.010
SNRPB2	small nuclear ribonucleoprotein polypeptide B	0.010
MKI67IP	MKI67 (FHA domain) interacting nucleolar phosphoprotein	0.010
TRAP1	TNF receptor-associated protein 1	0.010
ECSIT	ECSIT homolog (Drosophila)	0.010
RPL8	ribosomal protein L8	0.010
SHQ1	SHQ1 homolog (S. cerevisiae)	0.010
LSG1	large subunit GTPase 1 homolog (S. cerevisiae)	0.010
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.010