IMP: Integrative Multi-species Prediction

Homo sapiens

26 genes annotated in human

Multi-species View

gene silencing by rna

GO:0031047

Any process in which RNA molecules inactivate expression of target genes.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "gene silencing by rna"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "gene silencing by rna" (in gray)

Name	Description	Probability	Func Analog Organism
DICER1	dicer 1, ribonuclease type III	0.994
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.977
HDAC1	histone deacetylase 1	0.961	Worm
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.942
TNRC6A	trinucleotide repeat containing 6A	0.928
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.915
CSNK2B	casein kinase 2, beta polypeptide	0.838	Worm
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.660
HDAC2	histone deacetylase 2	0.560	Worm
TNRC6B	trinucleotide repeat containing 6B	0.515
RUVBL1	RuvB-like 1 (E. coli)	0.488	Worm
PABPC1	poly(A) binding protein, cytoplasmic 1	0.418	Mouse
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.409
EIF2C4	eukaryotic translation initiation factor 2C, 4	0.407
TNRC6C	trinucleotide repeat containing 6C	0.356	Human Mouse
ESR1	estrogen receptor 1	0.303
SRSF7	serine/arginine-rich splicing factor 7	0.267
SF3A3	splicing factor 3a, subunit 3, 60kDa	0.258
HSPA1A	heat shock 70kDa protein 1A	0.255	Fly
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.255
APC	adenomatous polyposis coli	0.235
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.212
NUP62	nucleoporin 62kDa	0.205
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.197
SNRPF	small nuclear ribonucleoprotein polypeptide F	0.190
SP1	Sp1 transcription factor	0.184
TARDBP	TAR DNA binding protein	0.179
SF1	splicing factor 1	0.170
EIF2C3	eukaryotic translation initiation factor 2C, 3	0.167
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.153
UBA2	ubiquitin-like modifier activating enzyme 2	0.143
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.138
RBBP4	retinoblastoma binding protein 4	0.132	Worm
ACTR6	ARP6 actin-related protein 6 homolog (yeast)	0.116
EIF3J	eukaryotic translation initiation factor 3, subunit J	0.109
RUVBL2	RuvB-like 2 (E. coli)	0.103	Worm
SNRPA1	small nuclear ribonucleoprotein polypeptide A'	0.095
PAN3	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)	0.092
WWOX	WW domain containing oxidoreductase	0.088
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.088
HSPA1B	heat shock 70kDa protein 1B	0.087	Fly
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.087
TRRAP	transformation/transcription domain-associated protein	0.082
CAPRIN1	cell cycle associated protein 1	0.079
ILF3	interleukin enhancer binding factor 3, 90kDa	0.076
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.076
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.075
KPNB1	karyopherin (importin) beta 1	0.071
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.068
RNPS1	RNA binding protein S1, serine-rich domain	0.067
EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	0.065
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.063
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.061
RPL23	ribosomal protein L23	0.061
SRSF10	serine/arginine-rich splicing factor 10	0.061
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.059	Fly
SNIP1	Smad nuclear interacting protein 1	0.059
ACTL6A	actin-like 6A	0.058	Fly
LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.058
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.058
SIRT1	sirtuin 1	0.055
SF3B1	splicing factor 3b, subunit 1, 155kDa	0.054
CSTF2	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	0.054	Worm
CPSF3	cleavage and polyadenylation specific factor 3, 73kDa	0.053
RBM10	RNA binding motif protein 10	0.053
CBX1	chromobox homolog 1	0.051
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.050
EED	embryonic ectoderm development	0.049
RBBP7	retinoblastoma binding protein 7	0.047	Worm
SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.046
DCP2	DCP2 decapping enzyme homolog (S. cerevisiae)	0.045
HCFC1	host cell factor C1 (VP16-accessory protein)	0.045
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.044	Fly
IPO8	importin 8	0.044
ADNP	activity-dependent neuroprotector homeobox	0.044
EDC3	enhancer of mRNA decapping 3 homolog (S. cerevisiae)	0.044
MYBBP1A	MYB binding protein (P160) 1a	0.042
IFIT2	interferon-induced protein with tetratricopeptide repeats 2	0.041
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.041
HMGB1	high mobility group box 1	0.040
CAND1	cullin-associated and neddylation-dissociated 1	0.039
XPO1	exportin 1 (CRM1 homolog, yeast)	0.039
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.039
ERH	enhancer of rudimentary homolog (Drosophila)	0.038
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.038
TSNAX	translin-associated factor X	0.038
SNRPE	small nuclear ribonucleoprotein polypeptide E	0.038
HIPK3	homeodomain interacting protein kinase 3	0.038
SP110	SP110 nuclear body protein	0.037
SF3A2	splicing factor 3a, subunit 2, 66kDa	0.037
CLNS1A	chloride channel, nucleotide-sensitive, 1A	0.036
CPSF2	cleavage and polyadenylation specific factor 2, 100kDa	0.036	Worm
MRPS15	mitochondrial ribosomal protein S15	0.036
MEOX2	mesenchyme homeobox 2	0.035
SOX10	SRY (sex determining region Y)-box 10	0.034
FNBP4	formin binding protein 4	0.034
DDX1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1	0.033
NXF1	nuclear RNA export factor 1	0.033
SSB	Sjogren syndrome antigen B (autoantigen La)	0.032
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.031
DAZL	deleted in azoospermia-like	0.030
SFRS18	splicing factor, arginine/serine-rich 18	0.029
UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)	0.029	Worm
DMAP1	DNA methyltransferase 1 associated protein 1	0.029
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.029
ZNHIT1	zinc finger, HIT-type containing 1	0.029	Worm
H2AFZ	H2A histone family, member Z	0.029	Worm
PAX3	paired box 3	0.028
EIF3I	eukaryotic translation initiation factor 3, subunit I	0.027
SCRIB	scribbled homolog (Drosophila)	0.027
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.027
SMG1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)	0.027
EIF3B	eukaryotic translation initiation factor 3, subunit B	0.027
FOXD3	forkhead box D3	0.026
GSPT1	G1 to S phase transition 1	0.026
WDR77	WD repeat domain 77	0.026
FXR1	fragile X mental retardation, autosomal homolog 1	0.026
DTX3L	deltex 3-like (Drosophila)	0.025
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.025	Worm
HAT1	histone acetyltransferase 1	0.025
HNRNPA0	heterogeneous nuclear ribonucleoprotein A0	0.024
IDE	insulin-degrading enzyme	0.024
KIAA1377	KIAA1377	0.024
YY1	YY1 transcription factor	0.024
SUB1	SUB1 homolog (S. cerevisiae)	0.024
G3BP2	GTPase activating protein (SH3 domain) binding protein 2	0.024
UBQLN1	ubiquilin 1	0.023
LUC7L3	LUC7-like 3 (S. cerevisiae)	0.023
MAPK14	mitogen-activated protein kinase 14	0.023
MED15	mediator complex subunit 15	0.023
CBX3	chromobox homolog 3	0.023
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.023
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.023
BAG3	BCL2-associated athanogene 3	0.022
CHD4	chromodomain helicase DNA binding protein 4	0.022
GCN1L1	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	0.022
POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	0.021
CSE1L	CSE1 chromosome segregation 1-like (yeast)	0.021	Worm
TCF4	transcription factor 4	0.021
GTF2A2	general transcription factor IIA, 2, 12kDa	0.021
IPO5	importin 5	0.021
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.021
IFIT5	interferon-induced protein with tetratricopeptide repeats 5	0.021
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.021
USP42	ubiquitin specific peptidase 42	0.021
MED21	mediator complex subunit 21	0.020
SUGP1	SURP and G patch domain containing 1	0.020
SMC3	structural maintenance of chromosomes 3	0.020
LSM10	LSM10, U7 small nuclear RNA associated	0.020
C19orf43	chromosome 19 open reading frame 43	0.020
SYMPK	symplekin	0.020
DAZAP1	DAZ associated protein 1	0.019
IFIT1	interferon-induced protein with tetratricopeptide repeats 1	0.019
NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive	0.019
NCOA3	nuclear receptor coactivator 3	0.019
BCS1L	BCS1-like (S. cerevisiae)	0.019
PSEN1	presenilin 1	0.019
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.018
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.018
CBX5	chromobox homolog 5	0.018
EGR1	early growth response 1	0.018
TTI1	Tel2 interacting protein 1 homolog (S. pombe)	0.018
CPSF6	cleavage and polyadenylation specific factor 6, 68kDa	0.018
LUC7L2	LUC7-like 2 (S. cerevisiae)	0.017
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.017
HSF2	heat shock transcription factor 2	0.017
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.017
SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)	0.017
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.017
MATR3	matrin 3	0.016
PARK7	Parkinson disease (autosomal recessive, early onset) 7	0.016
CREB1	cAMP responsive element binding protein 1	0.016
EIF2B1	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	0.016
C20orf20	chromosome 20 open reading frame 20	0.016
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.016
COPS3	COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)	0.016
API5	apoptosis inhibitor 5	0.016
FMR1	fragile X mental retardation 1	0.016
MANF	mesencephalic astrocyte-derived neurotrophic factor	0.016
BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	0.016
CNOT6	CCR4-NOT transcription complex, subunit 6	0.015
GEMIN4	gem (nuclear organelle) associated protein 4	0.015
BAG1	BCL2-associated athanogene	0.015
MSH6	mutS homolog 6 (E. coli)	0.015
VPS72	vacuolar protein sorting 72 homolog (S. cerevisiae)	0.015
JUNB	jun B proto-oncogene	0.015
BOLL	bol, boule-like (Drosophila)	0.015
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.015
SNRPD2	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	0.015
C19orf70	chromosome 19 open reading frame 70	0.014
PSIP1	PC4 and SFRS1 interacting protein 1	0.014
MORF4L1	mortality factor 4 like 1	0.014
ASF1A	ASF1 anti-silencing function 1 homolog A (S. cerevisiae)	0.014
SFPQ	splicing factor proline/glutamine-rich	0.014
NMT1	N-myristoyltransferase 1	0.014
PAPOLA	poly(A) polymerase alpha	0.014
TIMM17A	translocase of inner mitochondrial membrane 17 homolog A (yeast)	0.014
PUM2	pumilio homolog 2 (Drosophila)	0.014
MAPK1	mitogen-activated protein kinase 1	0.014
MTA1	metastasis associated 1	0.014
UBQLN4	ubiquilin 4	0.014
NIPBL	Nipped-B homolog (Drosophila)	0.014
AMD1	adenosylmethionine decarboxylase 1	0.014
RBM8A	RNA binding motif protein 8A	0.014
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.013
SRPK1	SRSF protein kinase 1	0.013
IER2	immediate early response 2	0.013
IPO4	importin 4	0.013
EIF1AX	eukaryotic translation initiation factor 1A, X-linked	0.013
TOP1	topoisomerase (DNA) I	0.013
FRA10AC1	fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1	0.013
MORF4L2	mortality factor 4 like 2	0.013
FUS	fused in sarcoma	0.013
SF3B14	splicing factor 3B, 14 kDa subunit	0.013
SERBP1	SERPINE1 mRNA binding protein 1	0.013
EP300	E1A binding protein p300	0.013
IFI44	interferon-induced protein 44	0.013
BTAF1	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae)	0.013
SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0.013	Worm
SOX2	SRY (sex determining region Y)-box 2	0.013
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.012
SF3A1	splicing factor 3a, subunit 1, 120kDa	0.012	Worm
ARL6IP1	ADP-ribosylation factor-like 6 interacting protein 1	0.012
CEP57	centrosomal protein 57kDa	0.012
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.012
NOC4L	nucleolar complex associated 4 homolog (S. cerevisiae)	0.012
CREBZF	CREB/ATF bZIP transcription factor	0.012
DUT	deoxyuridine triphosphatase	0.012
PARP12	poly (ADP-ribose) polymerase family, member 12	0.012
MAPK9	mitogen-activated protein kinase 9	0.012
THUMPD1	THUMP domain containing 1	0.012
TCERG1	transcription elongation regulator 1	0.012	Worm
RBM14	RNA binding motif protein 14	0.012
MRPL18	mitochondrial ribosomal protein L18	0.012
SRSF3	serine/arginine-rich splicing factor 3	0.012
FTSJD2	FtsJ methyltransferase domain containing 2	0.012
CDK2AP1	cyclin-dependent kinase 2 associated protein 1	0.012
DPCD	deleted in primary ciliary dyskinesia homolog (mouse)	0.012
KLF6	Kruppel-like factor 6	0.012
CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.012
YEATS4	YEATS domain containing 4	0.012
SCAF4	SR-related CTD-associated factor 4	0.012
MBNL1	muscleblind-like (Drosophila)	0.012
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.012
UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	0.011
CARM1	coactivator-associated arginine methyltransferase 1	0.011
NCOA2	nuclear receptor coactivator 2	0.011
C17orf85	chromosome 17 open reading frame 85	0.011
FTSJ3	FtsJ homolog 3 (E. coli)	0.011
UPF3B	UPF3 regulator of nonsense transcripts homolog B (yeast)	0.011
MYSM1	Myb-like, SWIRM and MPN domains 1	0.011
PRPF6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	0.011
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.011	Worm
MDH2	malate dehydrogenase 2, NAD (mitochondrial)	0.011
PAIP2	poly(A) binding protein interacting protein 2	0.011
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.011
TIA1	TIA1 cytotoxic granule-associated RNA binding protein	0.011
FERMT2	fermitin family member 2	0.011
UTP18	UTP18, small subunit (SSU) processome component, homolog (yeast)	0.011
TCOF1	Treacher Collins-Franceschetti syndrome 1	0.011
PDLIM7	PDZ and LIM domain 7 (enigma)	0.011
CYLD	cylindromatosis (turban tumor syndrome)	0.011
CTNNBL1	catenin, beta like 1	0.011
HMGN2	high mobility group nucleosomal binding domain 2	0.011
HOXA9	homeobox A9	0.011
MTF2	metal response element binding transcription factor 2	0.011
COPS2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	0.011
DDX56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56	0.011
VTA1	Vps20-associated 1 homolog (S. cerevisiae)	0.011
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.011
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	0.010
IFIT3	interferon-induced protein with tetratricopeptide repeats 3	0.010
TRIM25	tripartite motif containing 25	0.010
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.010
RECQL	RecQ protein-like (DNA helicase Q1-like)	0.010
RPL11	ribosomal protein L11	0.010
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.010
RSF1	remodeling and spacing factor 1	0.010
USP22	ubiquitin specific peptidase 22	0.010
NUDT21	nudix (nucleoside diphosphate linked moiety X)-type motif 21	0.010	Worm
XPO7	exportin 7	0.010
RPN1	ribophorin I	0.010
C15orf63	chromosome 15 open reading frame 63	0.010
AZIN1	antizyme inhibitor 1	0.010
POGZ	pogo transposable element with ZNF domain	0.010
BMI1	BMI1 polycomb ring finger oncogene	0.010
DDX60L	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like	0.010
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.010