IMP: Integrative Multi-species Prediction

Homo sapiens

94 genes annotated in human

cellular response to transforming growth factor beta stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to transforming growth factor beta stimulus"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cellular response to transforming growth factor beta stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	1.000	Human
SMAD4	SMAD family member 4	1.000
SMAD7	SMAD family member 7	1.000
JUN	jun proto-oncogene	1.000
SMAD3	SMAD family member 3	1.000
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.999	Human Fly
TP53	tumor protein p53	0.999	Mouse
FN1	fibronectin 1	0.998	Rat
FHL2	four and a half LIM domains 2	0.998
SMAD2	SMAD family member 2	0.997
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.997
FYN	FYN oncogene related to SRC, FGR, YES	0.995	Human Mouse
SMAD1	SMAD family member 1	0.995	Human Fly
TGFB1	transforming growth factor, beta 1	0.994
FLNA	filamin A, alpha	0.989
ATF2	activating transcription factor 2	0.988	Human
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.988	Fly
SMAD5	SMAD family member 5	0.981	Human Mouse Fly
PDIA3	protein disulfide isomerase family A, member 3	0.970
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.965
SKIL	SKI-like oncogene	0.954
TRIM33	tripartite motif containing 33	0.952
HCK	hemopoietic cell kinase	0.949	Human
ATF3	activating transcription factor 3	0.946	Human
ENG	endoglin	0.943
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.939	Human
BCAR1	breast cancer anti-estrogen resistance 1	0.930
COL1A1	collagen, type I, alpha 1	0.927	Human Rat
JUNB	jun B proto-oncogene	0.922	Human
COL3A1	collagen, type III, alpha 1	0.910
MAPK8	mitogen-activated protein kinase 8	0.907
TGFBR1	transforming growth factor, beta receptor 1	0.901
SNX6	sorting nexin 6	0.896
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.884
COL4A1	collagen, type IV, alpha 1	0.880
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.871
PML	promyelocytic leukemia	0.861	Mouse
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.842	Human
ELN	elastin	0.837
HIPK2	homeodomain interacting protein kinase 2	0.836
EP300	E1A binding protein p300	0.815
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.788
SIRT1	sirtuin 1	0.782	Mouse
COL1A2	collagen, type I, alpha 2	0.758
VCL	vinculin	0.702
MAP2K4	mitogen-activated protein kinase kinase 4	0.692
TGFB3	transforming growth factor, beta 3	0.689
BMP2	bone morphogenetic protein 2	0.685
FLNB	filamin B, beta	0.670
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.667
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.667
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.640
DUSP1	dual specificity phosphatase 1	0.630
PIAS4	protein inhibitor of activated STAT, 4	0.627
TBX5	T-box 5	0.616
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.615	Human
LOX	lysyl oxidase	0.606
TCF4	transcription factor 4	0.602
ABI2	abl-interactor 2	0.596
ITGB4	integrin, beta 4	0.594	Human
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.580
SNX9	sorting nexin 9	0.563
HDAC4	histone deacetylase 4	0.555
SNX33	sorting nexin 33	0.554
NOSTRIN	nitric oxide synthase trafficker	0.551
COL5A2	collagen, type V, alpha 2	0.545	Human
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.545
COL6A1	collagen, type VI, alpha 1	0.536
CXXC5	CXXC finger protein 5	0.532
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.526	Human
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.511
COL5A1	collagen, type V, alpha 1	0.510	Human
SYK	spleen tyrosine kinase	0.488
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.483
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.480
VCAM1	vascular cell adhesion molecule 1	0.470
IGFBP5	insulin-like growth factor binding protein 5	0.434
ADAM10	ADAM metallopeptidase domain 10	0.417
PXN	paxillin	0.416
BLNK	B-cell linker	0.411
PTK2	PTK2 protein tyrosine kinase 2	0.407
FSTL1	follistatin-like 1	0.400
ZMYM2	zinc finger, MYM-type 2	0.391
SNX1	sorting nexin 1	0.389	Human
JUND	jun D proto-oncogene	0.383	Human
DDR2	discoidin domain receptor tyrosine kinase 2	0.378
CGA	glycoprotein hormones, alpha polypeptide	0.375
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.373
BMP4	bone morphogenetic protein 4	0.358
RANBP9	RAN binding protein 9	0.356
ACVR1	activin A receptor, type I	0.354
CCR5	chemokine (C-C motif) receptor 5	0.352
SNX2	sorting nexin 2	0.343	Human
ZNF512B	zinc finger protein 512B	0.339
COL6A2	collagen, type VI, alpha 2	0.336
NCK2	NCK adaptor protein 2	0.329
TPBG	trophoblast glycoprotein	0.321
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.319
YY1	YY1 transcription factor	0.318
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.312
TGIF1	TGFB-induced factor homeobox 1	0.306	Zebrafish
CREBBP	CREB binding protein	0.303
CTBP2	C-terminal binding protein 2	0.297
FKBP1A	FK506 binding protein 1A, 12kDa	0.294
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.290
IRF2BP1	interferon regulatory factor 2 binding protein 1	0.286
TLN1	talin 1	0.283	Human
RUNX1	runt-related transcription factor 1	0.281	Mouse
BMPR1A	bone morphogenetic protein receptor, type IA	0.277	Human Fly
MAGEA2	melanoma antigen family A, 2	0.276
FBLN2	fibulin 2	0.274
IER2	immediate early response 2	0.273
ITGB5	integrin, beta 5	0.271
SFN	stratifin	0.269
FBN1	fibrillin 1	0.262	Mouse
COL18A1	collagen, type XVIII, alpha 1	0.259
PLEC	plectin	0.259
LAMB1	laminin, beta 1	0.258
SMAD6	SMAD family member 6	0.250
TBX2	T-box 2	0.246
GDF5	growth differentiation factor 5	0.244
THBS1	thrombospondin 1	0.240
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.240
BMP1	bone morphogenetic protein 1	0.235
ADAM15	ADAM metallopeptidase domain 15	0.234	Human
FBLN1	fibulin 1	0.233
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.231
BGN	biglycan	0.229	Human
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.228
TGFB2	transforming growth factor, beta 2	0.227
CDK6	cyclin-dependent kinase 6	0.226
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.219	Human
ERBB2IP	erbb2 interacting protein	0.210
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.209
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.206
SFRP4	secreted frizzled-related protein 4	0.203
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.202
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.200	Mouse
POU5F1	POU class 5 homeobox 1	0.196
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.194
ITGA6	integrin, alpha 6	0.193	Human
PIAS1	protein inhibitor of activated STAT, 1	0.192
FBXL12	F-box and leucine-rich repeat protein 12	0.192
PDCD6IP	programmed cell death 6 interacting protein	0.189
SNIP1	Smad nuclear interacting protein 1	0.189
LPXN	leupaxin	0.189	Human
LRP1	low density lipoprotein receptor-related protein 1	0.188
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.187
COL16A1	collagen, type XVI, alpha 1	0.185
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.182
DLG1	discs, large homolog 1 (Drosophila)	0.182
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.178
STRADA	STE20-related kinase adaptor alpha	0.177
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.175
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.175
MAPK10	mitogen-activated protein kinase 10	0.175
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.174
MIB1	mindbomb homolog 1 (Drosophila)	0.172
IGFBP3	insulin-like growth factor binding protein 3	0.170
MAPK14	mitogen-activated protein kinase 14	0.170	Fly
SP1	Sp1 transcription factor	0.167
DCN	decorin	0.164	Human
COL8A1	collagen, type VIII, alpha 1	0.164
CYTH1	cytohesin 1	0.163
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.163	Human
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.163
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.161
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.161
SOCS3	suppressor of cytokine signaling 3	0.158
PTPRC	protein tyrosine phosphatase, receptor type, C	0.154
PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.153
PTEN	phosphatase and tensin homolog	0.152
ING2	inhibitor of growth family, member 2	0.151
PLAU	plasminogen activator, urokinase	0.151
LUM	lumican	0.150	Human
NRP1	neuropilin 1	0.148
BTBD2	BTB (POZ) domain containing 2	0.146
LTBP1	latent transforming growth factor beta binding protein 1	0.146
LMNA	lamin A/C	0.144
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.143
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.141
MAPK9	mitogen-activated protein kinase 9	0.141
FNBP1	formin binding protein 1	0.139
MAPK7	mitogen-activated protein kinase 7	0.134
PCGF2	polycomb group ring finger 2	0.134
TIMP3	TIMP metallopeptidase inhibitor 3	0.134
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.132
BHLHE40	basic helix-loop-helix family, member e40	0.129
SNAI1	snail homolog 1 (Drosophila)	0.128
MEF2A	myocyte enhancer factor 2A	0.128	Human
MFAP2	microfibrillar-associated protein 2	0.126
USP9X	ubiquitin specific peptidase 9, X-linked	0.126
CALD1	caldesmon 1	0.122
FZD1	frizzled homolog 1 (Drosophila)	0.120
RANBP3	RAN binding protein 3	0.118
FOXD3	forkhead box D3	0.117
DPT	dermatopontin	0.115
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.115
APOE	apolipoprotein E	0.113
MXRA5	matrix-remodelling associated 5	0.112
JDP2	Jun dimerization protein 2	0.109	Human
LTBP2	latent transforming growth factor beta binding protein 2	0.109
CTBP1	C-terminal binding protein 1	0.109
WIPF1	WAS/WASL interacting protein family, member 1	0.108
OTUD5	OTU domain containing 5	0.106
POU3F2	POU class 3 homeobox 2	0.106
COL6A3	collagen, type VI, alpha 3	0.106
MYO6	myosin VI	0.105
POSTN	periostin, osteoblast specific factor	0.105
LRP6	low density lipoprotein receptor-related protein 6	0.105
HUWE1	HECT, UBA and WWE domain containing 1	0.105
EPS8	epidermal growth factor receptor pathway substrate 8	0.104
PLXDC1	plexin domain containing 1	0.104
COL2A1	collagen, type II, alpha 1	0.102	Human
SALL2	sal-like 2 (Drosophila)	0.102
CALR	calreticulin	0.100
PAX8	paired box 8	0.100
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.099
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.099
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.099	Human
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.098
FNDC1	fibronectin type III domain containing 1	0.098
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.098	Human
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.097	Mouse
KDM6B	lysine (K)-specific demethylase 6B	0.097
PGR	progesterone receptor	0.096
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.095
PLAT	plasminogen activator, tissue	0.095
COL11A1	collagen, type XI, alpha 1	0.094	Human
GATA4	GATA binding protein 4	0.093
GAS7	growth arrest-specific 7	0.092
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.092
AQP1	aquaporin 1 (Colton blood group)	0.092
PLAUR	plasminogen activator, urokinase receptor	0.092
CUL7	cullin 7	0.091
CTGF	connective tissue growth factor	0.091
DCAF7	DDB1 and CUL4 associated factor 7	0.091
AXIN1	axin 1	0.091	Mouse
AR	androgen receptor	0.090
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.090
WNT2	wingless-type MMTV integration site family member 2	0.089
ZFYVE9	zinc finger, FYVE domain containing 9	0.088
FGF18	fibroblast growth factor 18	0.087
SH3PXD2A	SH3 and PX domains 2A	0.087
LCK	lymphocyte-specific protein tyrosine kinase	0.086	Human
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.086
THBS2	thrombospondin 2	0.085	Human
LIMS1	LIM and senescent cell antigen-like domains 1	0.085
VCAN	versican	0.085
RNF11	ring finger protein 11	0.082
DAXX	death-domain associated protein	0.082
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.080
CAV2	caveolin 2	0.079	Mouse
INHBA	inhibin, beta A	0.078
FHL3	four and a half LIM domains 3	0.078	Human
SOD3	superoxide dismutase 3, extracellular	0.078
CPNE6	copine VI (neuronal)	0.078
SNX5	sorting nexin 5	0.077	Human
ITGA7	integrin, alpha 7	0.077	Human
TADA3	transcriptional adaptor 3	0.077
F2R	coagulation factor II (thrombin) receptor	0.077
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.076
CEP250	centrosomal protein 250kDa	0.076
CRLF1	cytokine receptor-like factor 1	0.076
HSPB1	heat shock 27kDa protein 1	0.075
ACAN	aggrecan	0.075
JAG2	jagged 2	0.074
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.074
HIPK3	homeodomain interacting protein kinase 3	0.073	Human
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.073
NUAK1	NUAK family, SNF1-like kinase, 1	0.073
EDNRA	endothelin receptor type A	0.073
PDIA4	protein disulfide isomerase family A, member 4	0.071
TDG	thymine-DNA glycosylase	0.071
COL10A1	collagen, type X, alpha 1	0.071
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.070
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.069
BANP	BTG3 associated nuclear protein	0.069
TRIO	triple functional domain (PTPRF interacting)	0.069
WISP1	WNT1 inducible signaling pathway protein 1	0.069
MFAP4	microfibrillar-associated protein 4	0.068
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.068
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.068
GLT8D2	glycosyltransferase 8 domain containing 2	0.068
CBX1	chromobox homolog 1	0.067
BCL3	B-cell CLL/lymphoma 3	0.067
YAP1	Yes-associated protein 1	0.067
AEBP1	AE binding protein 1	0.067
KAT2B	K(lysine) acetyltransferase 2B	0.066
FAP	fibroblast activation protein, alpha	0.065
MTMR4	myotubularin related protein 4	0.065
GLIS2	GLIS family zinc finger 2	0.065
PRKCB	protein kinase C, beta	0.065
RFWD2	ring finger and WD repeat domain 2	0.064
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.064	Human
USP15	ubiquitin specific peptidase 15	0.063
SOX7	SRY (sex determining region Y)-box 7	0.063	Human
DCP1B	DCP1 decapping enzyme homolog B (S. cerevisiae)	0.063
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.062
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.062
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.062
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.062
PHF21A	PHD finger protein 21A	0.062
MAGEF1	melanoma antigen family F, 1	0.061
PRRC2B	proline-rich coiled-coil 2B	0.061
KLF5	Kruppel-like factor 5 (intestinal)	0.061
ISLR	immunoglobulin superfamily containing leucine-rich repeat	0.061
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.061
SFPQ	splicing factor proline/glutamine-rich	0.061
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.060
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.060
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.059
SH3D19	SH3 domain containing 19	0.059
FNDC3B	fibronectin type III domain containing 3B	0.059
DMWD	dystrophia myotonica, WD repeat containing	0.058
RARA	retinoic acid receptor, alpha	0.058
KDM5D	lysine (K)-specific demethylase 5D	0.058
RUNX2	runt-related transcription factor 2	0.058
VEGFC	vascular endothelial growth factor C	0.058
HOXA1	homeobox A1	0.058
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.057
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.057
STRADB	STE20-related kinase adaptor beta	0.057
FSTL3	follistatin-like 3 (secreted glycoprotein)	0.057
PRKG1	protein kinase, cGMP-dependent, type I	0.056
COL14A1	collagen, type XIV, alpha 1	0.056
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.056
PCOLCE	procollagen C-endopeptidase enhancer	0.056
MYO10	myosin X	0.055
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.055
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.055
OLFML2B	olfactomedin-like 2B	0.055
HDAC9	histone deacetylase 9	0.054
TWIST1	twist homolog 1 (Drosophila)	0.054
DUSP9	dual specificity phosphatase 9	0.053
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.053
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.053
CAV1	caveolin 1, caveolae protein, 22kDa	0.053	Mouse
SOX9	SRY (sex determining region Y)-box 9	0.052
MAPK11	mitogen-activated protein kinase 11	0.052	Fly
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.052	Human
FOSL1	FOS-like antigen 1	0.052	Human
NID2	nidogen 2 (osteonidogen)	0.051
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.051
WRN	Werner syndrome, RecQ helicase-like	0.051
FBXL15	F-box and leucine-rich repeat protein 15	0.051
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.051
PECAM1	platelet/endothelial cell adhesion molecule	0.051
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.050
MYOD1	myogenic differentiation 1	0.050
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.050
ADAM12	ADAM metallopeptidase domain 12	0.050	Human
MSX1	msh homeobox 1	0.049
GATA2	GATA binding protein 2	0.049
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.049
PRPF8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	0.048
CTHRC1	collagen triple helix repeat containing 1	0.048
OBSL1	obscurin-like 1	0.048
LIMS2	LIM and senescent cell antigen-like domains 2	0.048	Human
SELPLG	selectin P ligand	0.048
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.048
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.048	Human
EGR1	early growth response 1	0.048
SFTPC	surfactant protein C	0.048
APP	amyloid beta (A4) precursor protein	0.048
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.048
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.047
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.047
PRKCDBP	protein kinase C, delta binding protein	0.047
EPAS1	endothelial PAS domain protein 1	0.047
TYRP1	tyrosinase-related protein 1	0.047
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.047
MAPK1	mitogen-activated protein kinase 1	0.047
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.046	Human
NCK1	NCK adaptor protein 1	0.046
MFAP5	microfibrillar associated protein 5	0.046
CTSK	cathepsin K	0.046
SOX5	SRY (sex determining region Y)-box 5	0.046
TNS4	tensin 4	0.046
SF3B1	splicing factor 3b, subunit 1, 155kDa	0.046
ZMYND11	zinc finger, MYND-type containing 11	0.046
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.045
FOXC1	forkhead box C1	0.045
KCTD17	potassium channel tetramerisation domain containing 17	0.045
KLF2	Kruppel-like factor 2 (lung)	0.045
ACTN1	actinin, alpha 1	0.044
GJA4	gap junction protein, alpha 4, 37kDa	0.044
CLNS1A	chloride channel, nucleotide-sensitive, 1A	0.044
COL8A2	collagen, type VIII, alpha 2	0.044
COL12A1	collagen, type XII, alpha 1	0.044
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.044
MRC2	mannose receptor, C type 2	0.043
SFRP1	secreted frizzled-related protein 1	0.043
SLIT3	slit homolog 3 (Drosophila)	0.043
ITGB7	integrin, beta 7	0.043	Human
DNM1	dynamin 1	0.043
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.043
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.043
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.043
FOXG1	forkhead box G1	0.043
SFTPD	surfactant protein D	0.042	Human
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.042
HYAL1	hyaluronoglucosaminidase 1	0.042	Human
RAP1B	RAP1B, member of RAS oncogene family	0.042
FOXF1	forkhead box F1	0.042
FAS	Fas (TNF receptor superfamily, member 6)	0.042
FBXO11	F-box protein 11	0.042
PIAS2	protein inhibitor of activated STAT, 2	0.042
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.042
ACVR2B	activin A receptor, type IIB	0.042
TRAPPC8	trafficking protein particle complex 8	0.041
UNC5B	unc-5 homolog B (C. elegans)	0.041
OCIAD1	OCIA domain containing 1	0.041
POU3F1	POU class 3 homeobox 1	0.041
THY1	Thy-1 cell surface antigen	0.041
TP73	tumor protein p73	0.041
NRG1	neuregulin 1	0.041
F3	coagulation factor III (thromboplastin, tissue factor)	0.041
INHBB	inhibin, beta B	0.041
LRRC17	leucine rich repeat containing 17	0.041
TGFBR3	transforming growth factor, beta receptor III	0.040
FOXF2	forkhead box F2	0.040
PARVA	parvin, alpha	0.040
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.040
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.040
FBLIM1	filamin binding LIM protein 1	0.040	Human
KIAA0232	KIAA0232	0.040
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.040
COMP	cartilage oligomeric matrix protein	0.040	Human
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.040
BAG6	BCL2-associated athanogene 6	0.040
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.040	Mouse Rat
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.039
BCR	breakpoint cluster region	0.039
FBN2	fibrillin 2	0.039	Mouse
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.039
SNAI2	snail homolog 2 (Drosophila)	0.039
CD34	CD34 molecule	0.039
ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	0.039
CD248	CD248 molecule, endosialin	0.039
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.039
EFEMP1	EGF containing fibulin-like extracellular matrix protein 1	0.039
KLF10	Kruppel-like factor 10	0.039
KDM2A	lysine (K)-specific demethylase 2A	0.038
MED28	mediator complex subunit 28	0.038
TCAP	titin-cap (telethonin)	0.038
ARRB2	arrestin, beta 2	0.038
MAP2K7	mitogen-activated protein kinase kinase 7	0.038
PACSIN3	protein kinase C and casein kinase substrate in neurons 3	0.038
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.038
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.038
CSF1R	colony stimulating factor 1 receptor	0.038
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.038
GPR124	G protein-coupled receptor 124	0.038
HCLS1	hematopoietic cell-specific Lyn substrate 1	0.038
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.038
NLK	nemo-like kinase	0.038
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.038
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.037
CXXC1	CXXC finger protein 1	0.037
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.037
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.037
ATXN7	ataxin 7	0.037
CXCL12	chemokine (C-X-C motif) ligand 12	0.037
COL5A3	collagen, type V, alpha 3	0.037	Human
NQO1	NAD(P)H dehydrogenase, quinone 1	0.037
PXDN	peroxidasin homolog (Drosophila)	0.037
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.037
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.036
FOSL2	FOS-like antigen 2	0.036	Human
TNXB	tenascin XB	0.036
POLD3	polymerase (DNA-directed), delta 3, accessory subunit	0.036
SDC2	syndecan 2	0.036
TCF12	transcription factor 12	0.036
CRELD2	cysteine-rich with EGF-like domains 2	0.036
ANGPTL4	angiopoietin-like 4	0.036
PLEKHO1	pleckstrin homology domain containing, family O member 1	0.036
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.036
SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.036
MARK4	MAP/microtubule affinity-regulating kinase 4	0.036
TNC	tenascin C	0.035
PTRF	polymerase I and transcript release factor	0.035
ANGPTL2	angiopoietin-like 2	0.035
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.035	Human
RFX1	regulatory factor X, 1 (influences HLA class II expression)	0.035
ANTXR2	anthrax toxin receptor 2	0.035
SULF1	sulfatase 1	0.035
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.035
EPHA2	EPH receptor A2	0.035
FZD2	frizzled homolog 2 (Drosophila)	0.035
AGRN	agrin	0.035
IRS4	insulin receptor substrate 4	0.035
NRP2	neuropilin 2	0.035
SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.035
LEF1	lymphoid enhancer-binding factor 1	0.035
FZD7	frizzled homolog 7 (Drosophila)	0.035
GREM1	gremlin 1	0.034
SEC24B	SEC24 family, member B (S. cerevisiae)	0.034
ATM	ataxia telangiectasia mutated	0.034
PACS1	phosphofurin acidic cluster sorting protein 1	0.034
DLX4	distal-less homeobox 4	0.034
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.034
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.034
MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	0.034
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.034
PTK6	PTK6 protein tyrosine kinase 6	0.034	Human
GPNMB	glycoprotein (transmembrane) nmb	0.034
KLF4	Kruppel-like factor 4 (gut)	0.034
CD59	CD59 molecule, complement regulatory protein	0.034
LOXL2	lysyl oxidase-like 2	0.034
SPRR2A	small proline-rich protein 2A	0.034
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.033
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.033
TTN	titin	0.033
RXRA	retinoid X receptor, alpha	0.033
PPIC	peptidylprolyl isomerase C (cyclophilin C)	0.033
SOX11	SRY (sex determining region Y)-box 11	0.033
GDF6	growth differentiation factor 6	0.033
GJA1	gap junction protein, alpha 1, 43kDa	0.033
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.033
PAPOLA	poly(A) polymerase alpha	0.033
PPP1R13L	protein phosphatase 1, regulatory (inhibitor) subunit 13 like	0.033
EFNB2	ephrin-B2	0.033
MYST1	MYST histone acetyltransferase 1	0.033
RHOB	ras homolog gene family, member B	0.033
CLTC	clathrin, heavy chain (Hc)	0.033
SPARCL1	SPARC-like 1 (hevin)	0.033
COLEC12	collectin sub-family member 12	0.033
NOTCH3	notch 3	0.032
GJB3	gap junction protein, beta 3, 31kDa	0.032
GSN	gelsolin	0.032
IGFBP4	insulin-like growth factor binding protein 4	0.032
CPSF1	cleavage and polyadenylation specific factor 1, 160kDa	0.032
CDK9	cyclin-dependent kinase 9	0.032
VTN	vitronectin	0.032
RB1CC1	RB1-inducible coiled-coil 1	0.032
MYL9	myosin, light chain 9, regulatory	0.032
ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	0.032
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.032	Human
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	0.032
SHH	sonic hedgehog	0.031
ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)	0.031
PIP5K1C	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	0.031
CBX6	chromobox homolog 6	0.031
USPL1	ubiquitin specific peptidase like 1	0.031
ATF7IP	activating transcription factor 7 interacting protein	0.031
WIF1	WNT inhibitory factor 1	0.031
PRSS23	protease, serine, 23	0.031
CNOT4	CCR4-NOT transcription complex, subunit 4	0.031
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.031
LAMB2	laminin, beta 2 (laminin S)	0.031
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.031
ITIH5	inter-alpha (globulin) inhibitor H5	0.031
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.030
DMPK	dystrophia myotonica-protein kinase	0.030
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.030
ZEB1	zinc finger E-box binding homeobox 1	0.030	Mouse Rat
CTTN	cortactin	0.030
COL13A1	collagen, type XIII, alpha 1	0.030
PRRX1	paired related homeobox 1	0.030
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.030	Human Mouse
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.030
TOX4	TOX high mobility group box family member 4	0.030
SGCE	sarcoglycan, epsilon	0.030
DDIT3	DNA-damage-inducible transcript 3	0.030
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.030
MZT2B	mitotic spindle organizing protein 2B	0.030
EMP1	epithelial membrane protein 1	0.029
MEF2D	myocyte enhancer factor 2D	0.029	Human
STC2	stanniocalcin 2	0.029
SYNPO	synaptopodin	0.029
ITGA8	integrin, alpha 8	0.029	Human
MATK	megakaryocyte-associated tyrosine kinase	0.029
BMP3	bone morphogenetic protein 3	0.029
LAMA2	laminin, alpha 2	0.029
RBBP5	retinoblastoma binding protein 5	0.029
LRRC15	leucine rich repeat containing 15	0.029
NDN	necdin homolog (mouse)	0.029
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.029	Human
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.029
NEURL4	neuralized homolog 4 (Drosophila)	0.029
APC	adenomatous polyposis coli	0.029
DACH1	dachshund homolog 1 (Drosophila)	0.029
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.029
GLI3	GLI family zinc finger 3	0.028
CRIP2	cysteine-rich protein 2	0.028
SOX2	SRY (sex determining region Y)-box 2	0.028	Human
LEP	leptin	0.028
DKK3	dickkopf homolog 3 (Xenopus laevis)	0.028
SLCO2A1	solute carrier organic anion transporter family, member 2A1	0.028
ZNF282	zinc finger protein 282	0.028
ZBED5	zinc finger, BED-type containing 5	0.028
SFTPB	surfactant protein B	0.028
FGF8	fibroblast growth factor 8 (androgen-induced)	0.028
EPHB4	EPH receptor B4	0.028
MEST	mesoderm specific transcript homolog (mouse)	0.028
ACVR1B	activin A receptor, type IB	0.028	Human
JAG1	jagged 1	0.028
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.028
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.028
DOCK8	dedicator of cytokinesis 8	0.028
ARRDC3	arrestin domain containing 3	0.028
COPZ2	coatomer protein complex, subunit zeta 2	0.028
GSK3B	glycogen synthase kinase 3 beta	0.028
ILK	integrin-linked kinase	0.028
FILIP1L	filamin A interacting protein 1-like	0.028
WFDC1	WAP four-disulfide core domain 1	0.028
FANCD2	Fanconi anemia, complementation group D2	0.027
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.027
SOX17	SRY (sex determining region Y)-box 17	0.027	Human
CD9	CD9 molecule	0.027
ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15	0.027
FGF2	fibroblast growth factor 2 (basic)	0.027
ANKRD13A	ankyrin repeat domain 13A	0.027
WISP2	WNT1 inducible signaling pathway protein 2	0.027
PTN	pleiotrophin	0.027
ITK	IL2-inducible T-cell kinase	0.027
CENPB	centromere protein B, 80kDa	0.027
MGP	matrix Gla protein	0.027
ARID3A	AT rich interactive domain 3A (BRIGHT-like)	0.027
SFRP2	secreted frizzled-related protein 2	0.027	Human
TIMP2	TIMP metallopeptidase inhibitor 2	0.027
RASSF7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7	0.027
NCOR1	nuclear receptor corepressor 1	0.027
PTPRN	protein tyrosine phosphatase, receptor type, N	0.027
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.027
SOX21	SRY (sex determining region Y)-box 21	0.026
HOXD9	homeobox D9	0.026
SDC4	syndecan 4	0.026
CDK13	cyclin-dependent kinase 13	0.026
CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	0.026
EDN3	endothelin 3	0.026
OLFML3	olfactomedin-like 3	0.026
SBF1	SET binding factor 1	0.026
RING1	ring finger protein 1	0.026
PCDH17	protocadherin 17	0.026
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.026
GRB10	growth factor receptor-bound protein 10	0.026
ZEB2	zinc finger E-box binding homeobox 2	0.026
HIC1	hypermethylated in cancer 1	0.026
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.026
KLF6	Kruppel-like factor 6	0.026
HDLBP	high density lipoprotein binding protein	0.026
CLDN18	claudin 18	0.026
ADAM9	ADAM metallopeptidase domain 9	0.026
H3F3A	H3 histone, family 3A	0.026
MAP2K5	mitogen-activated protein kinase kinase 5	0.026
SBNO2	strawberry notch homolog 2 (Drosophila)	0.026
SENP1	SUMO1/sentrin specific peptidase 1	0.026
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.026
CD63	CD63 molecule	0.026
DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)	0.026
SH3BP5	SH3-domain binding protein 5 (BTK-associated)	0.025
UNC45A	unc-45 homolog A (C. elegans)	0.025
EFNB1	ephrin-B1	0.025
SPOPL	speckle-type POZ protein-like	0.025
ANXA5	annexin A5	0.025
BTG2	BTG family, member 2	0.025
CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.025
PHIP	pleckstrin homology domain interacting protein	0.025
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.025
F13A1	coagulation factor XIII, A1 polypeptide	0.025
SPON2	spondin 2, extracellular matrix protein	0.025
SOX1	SRY (sex determining region Y)-box 1	0.025	Human
TGFBI	transforming growth factor, beta-induced, 68kDa	0.025
ACTA2	actin, alpha 2, smooth muscle, aorta	0.025
NF1	neurofibromin 1	0.025
SIX2	SIX homeobox 2	0.025
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.025
PFN2	profilin 2	0.025
PDLIM5	PDZ and LIM domain 5	0.025
DIO2	deiodinase, iodothyronine, type II	0.025
FOXA2	forkhead box A2	0.025
MED15	mediator complex subunit 15	0.025
LAMA5	laminin, alpha 5	0.024
NPNT	nephronectin	0.024	Mouse
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.024
STAB1	stabilin 1	0.024
USP25	ubiquitin specific peptidase 25	0.024
IGF1	insulin-like growth factor 1 (somatomedin C)	0.024
HOOK3	hook homolog 3 (Drosophila)	0.024
SH3GL1	SH3-domain GRB2-like 1	0.024
CDX2	caudal type homeobox 2	0.024
ADARB1	adenosine deaminase, RNA-specific, B1	0.024
MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	0.024
JAM2	junctional adhesion molecule 2	0.024
ZBTB7A	zinc finger and BTB domain containing 7A	0.024
CREB1	cAMP responsive element binding protein 1	0.024	Rat
TSC22D3	TSC22 domain family, member 3	0.024
CAPN6	calpain 6	0.024
PLLP	plasmolipin	0.024
NOV	nephroblastoma overexpressed gene	0.024
PHLDB1	pleckstrin homology-like domain, family B, member 1	0.024
SEPT11	septin 11	0.024
GPRC5B	G protein-coupled receptor, family C, group 5, member B	0.024
CLIC4	chloride intracellular channel 4	0.024
DPP8	dipeptidyl-peptidase 8	0.024
GPC1	glypican 1	0.024
COL17A1	collagen, type XVII, alpha 1	0.024
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.024
UBE2W	ubiquitin-conjugating enzyme E2W (putative)	0.024
MT1A	metallothionein 1A	0.024
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.023
GATA5	GATA binding protein 5	0.023
GTF2I	general transcription factor IIi	0.023
NT5E	5'-nucleotidase, ecto (CD73)	0.023
EGFL6	EGF-like-domain, multiple 6	0.023
CBX8	chromobox homolog 8	0.023
PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	0.023
EFR3A	EFR3 homolog A (S. cerevisiae)	0.023
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.023
CLDN5	claudin 5	0.023
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.023
SPHK1	sphingosine kinase 1	0.023
MDK	midkine (neurite growth-promoting factor 2)	0.023
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.023
IK	IK cytokine, down-regulator of HLA II	0.023
HMGA2	high mobility group AT-hook 2	0.023
DCBLD1	discoidin, CUB and LCCL domain containing 1	0.023
PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	0.023
ECM2	extracellular matrix protein 2, female organ and adipocyte specific	0.023
DCBLD2	discoidin, CUB and LCCL domain containing 2	0.023
PLXND1	plexin D1	0.023
TACR1	tachykinin receptor 1	0.023
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.023
LTK	leukocyte receptor tyrosine kinase	0.023
GAS6	growth arrest-specific 6	0.023
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.023	Human Mouse
KIAA1033	KIAA1033	0.023
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.023
PNPLA6	patatin-like phospholipase domain containing 6	0.023
DNAJC13	DnaJ (Hsp40) homolog, subfamily C, member 13	0.023
PUM1	pumilio homolog 1 (Drosophila)	0.023
ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12	0.023
WNT5A	wingless-type MMTV integration site family, member 5A	0.023
TACC1	transforming, acidic coiled-coil containing protein 1	0.023
GRIK3	glutamate receptor, ionotropic, kainate 3	0.022
HERC1	hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1	0.022
CYR61	cysteine-rich, angiogenic inducer, 61	0.022
CCDC48	coiled-coil domain containing 48	0.022
ZNF469	zinc finger protein 469	0.022
GEMIN6	gem (nuclear organelle) associated protein 6	0.022
ADAMTSL2	ADAMTS-like 2	0.022
HTRA3	HtrA serine peptidase 3	0.022	Mouse
PALLD	palladin, cytoskeletal associated protein	0.022
GNG12	guanine nucleotide binding protein (G protein), gamma 12	0.022
MAP2	microtubule-associated protein 2	0.022
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.022
C5AR1	complement component 5a receptor 1	0.022
DRD4	dopamine receptor D4	0.022