IMP: Integrative Multi-species Prediction

Homo sapiens

22 genes annotated in human

glycogen metabolic process

The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "glycogen metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "glycogen metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
INSR	insulin receptor	1.000
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	1.000	Yeast
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.999	Yeast
IRS2	insulin receptor substrate 2	0.898
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.869
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.817
GSK3B	glycogen synthase kinase 3 beta	0.681
IRS1	insulin receptor substrate 1	0.639
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.553
NCF1	neutrophil cytosolic factor 1	0.495
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.466
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.457	Rat
CREBBP	CREB binding protein	0.389
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.359
IGF1R	insulin-like growth factor 1 receptor	0.356	Human
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.344
GYS1	glycogen synthase 1 (muscle)	0.275
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.274
NOXA1	NADPH oxidase activator 1	0.266
PGK1	phosphoglycerate kinase 1	0.254
ITGB1BP3	integrin beta 1 binding protein 3	0.244
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.238	Yeast
PRKCSH	protein kinase C substrate 80K-H	0.237
VCP	valosin containing protein	0.223
AR	androgen receptor	0.213
IGF2R	insulin-like growth factor 2 receptor	0.204
GRB10	growth factor receptor-bound protein 10	0.186	Rat
HIPK2	homeodomain interacting protein kinase 2	0.183
FAF1	Fas (TNFRSF6) associated factor 1	0.175
FOXO3	forkhead box O3	0.162	Fly
KAT2B	K(lysine) acetyltransferase 2B	0.159
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.156	Worm
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.154	Worm
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.149
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.146
PICK1	protein interacting with PRKCA 1	0.146
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.127
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.126
NCOA2	nuclear receptor coactivator 2	0.123
CCND3	cyclin D3	0.120
RUNX1	runt-related transcription factor 1	0.119
BTRC	beta-transducin repeat containing	0.116
PRKCB	protein kinase C, beta	0.114
JAK2	Janus kinase 2	0.111
DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	0.094	Human
FBXW11	F-box and WD repeat domain containing 11	0.091
HR	hairless homolog (mouse)	0.089
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.089
GYG1	glycogenin 1	0.088	Yeast
SH3RF1	SH3 domain containing ring finger 1	0.086
LZTS2	leucine zipper, putative tumor suppressor 2	0.085
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.085
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.078
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.075	Yeast
GYG2	glycogenin 2	0.074	Yeast
SQSTM1	sequestosome 1	0.071
HIC1	hypermethylated in cancer 1	0.070
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.070
PRKCZ	protein kinase C, zeta	0.070	Human
SRP9	signal recognition particle 9kDa	0.069
CREB1	cAMP responsive element binding protein 1	0.068
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.068
FHL2	four and a half LIM domains 2	0.067
HMOX2	heme oxygenase (decycling) 2	0.067
DCAF7	DDB1 and CUL4 associated factor 7	0.066
PRKCA	protein kinase C, alpha	0.065
STAT5B	signal transducer and activator of transcription 5B	0.065
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.064
UBXN2A	UBX domain protein 2A	0.064
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.062
SMAD3	SMAD family member 3	0.061
CYBA	cytochrome b-245, alpha polypeptide	0.060
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.058
AXIN1	axin 1	0.058
AGL	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	0.057
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.055
EP300	E1A binding protein p300	0.055
SMAD2	SMAD family member 2	0.049
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.049
SH2B1	SH2B adaptor protein 1	0.049
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.046
PSEN1	presenilin 1	0.046
GHR	growth hormone receptor	0.045
RAB6A	RAB6A, member RAS oncogene family	0.045
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.045
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.044
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.043
CLTC	clathrin, heavy chain (Hc)	0.043
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.042
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.041
PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.040
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.040
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.040
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.039
CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	0.039
GCKR	glucokinase (hexokinase 4) regulator	0.039
RXRA	retinoid X receptor, alpha	0.038
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.037
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.036
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.036	Human
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.036
RAB5A	RAB5A, member RAS oncogene family	0.036
TRIM9	tripartite motif containing 9	0.036
CCDC115	coiled-coil domain containing 115	0.035
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.033
NUMB	numb homolog (Drosophila)	0.032
SRSF5	serine/arginine-rich splicing factor 5	0.032
NCOA6	nuclear receptor coactivator 6	0.032
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.031
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.030
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.030	Yeast
OSBP	oxysterol binding protein	0.030
GBAS	glioblastoma amplified sequence	0.029
CALR	calreticulin	0.029
SIRT1	sirtuin 1	0.028
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.027
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.027
CCND1	cyclin D1	0.026
FOXO1	forkhead box O1	0.026	Fly
GOLGA8B	golgin A8 family, member B	0.026
IL6R	interleukin 6 receptor	0.025
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.024
SYK	spleen tyrosine kinase	0.024
NCF4	neutrophil cytosolic factor 4, 40kDa	0.023
GYS2	glycogen synthase 2 (liver)	0.023
GABARAPL1	GABA(A) receptor-associated protein like 1	0.022
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.022
TUBA1A	tubulin, alpha 1a	0.022
EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	0.022
SESN2	sestrin 2	0.022
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.022
PPID	peptidylprolyl isomerase D	0.021
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.021
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.021
APC	adenomatous polyposis coli	0.021
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.021
GLIS2	GLIS family zinc finger 2	0.021
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.021
SH2D2A	SH2 domain containing 2A	0.020
RPTOR	regulatory associated protein of MTOR, complex 1	0.020
CARD11	caspase recruitment domain family, member 11	0.020
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.020
S100A1	S100 calcium binding protein A1	0.020
KDELR1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	0.020
GRB14	growth factor receptor-bound protein 14	0.019
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.019
RAB8A	RAB8A, member RAS oncogene family	0.019
JUP	junction plakoglobin	0.019
LDLR	low density lipoprotein receptor	0.019
HNF4A	hepatocyte nuclear factor 4, alpha	0.019
HYOU1	hypoxia up-regulated 1	0.019
ACACA	acetyl-CoA carboxylase alpha	0.019
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.018
PDPK1	3-phosphoinositide dependent protein kinase-1	0.018
RICTOR	RPTOR independent companion of MTOR, complex 2	0.018
CCND2	cyclin D2	0.018
SMEK1	SMEK homolog 1, suppressor of mek1 (Dictyostelium)	0.017
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.017
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.017
STX16	syntaxin 16	0.017
CCL14	chemokine (C-C motif) ligand 14	0.017
NR1D2	nuclear receptor subfamily 1, group D, member 2	0.017
TNIK	TRAF2 and NCK interacting kinase	0.017
DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.017
JAK1	Janus kinase 1	0.017
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.017
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.016
SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	0.016
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.016
CPD	carboxypeptidase D	0.016
ZFC3H1	zinc finger, C3H1-type containing	0.016
PHKB	phosphorylase kinase, beta	0.016
SDF4	stromal cell derived factor 4	0.016
ATXN3	ataxin 3	0.016
SETDB1	SET domain, bifurcated 1	0.015
PECAM1	platelet/endothelial cell adhesion molecule	0.015
TSC22D1	TSC22 domain family, member 1	0.015
SAMD4B	sterile alpha motif domain containing 4B	0.015
MAPT	microtubule-associated protein tau	0.015
CDCP1	CUB domain containing protein 1	0.015
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.015
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.015
CSNK2B	casein kinase 2, beta polypeptide	0.014
DLG1	discs, large homolog 1 (Drosophila)	0.014
PFKL	phosphofructokinase, liver	0.014
PYGM	phosphorylase, glycogen, muscle	0.014	Rat
S100A2	S100 calcium binding protein A2	0.014
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.014
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.014
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.014
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.014
INPPL1	inositol polyphosphate phosphatase-like 1	0.014
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.013
IGFBP3	insulin-like growth factor binding protein 3	0.013
S100A6	S100 calcium binding protein A6	0.013
SH2D1A	SH2 domain containing 1A	0.013
SCP2	sterol carrier protein 2	0.013
POFUT1	protein O-fucosyltransferase 1	0.013
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.013
CCHCR1	coiled-coil alpha-helical rod protein 1	0.013
BAG3	BCL2-associated athanogene 3	0.013
SORBS2	sorbin and SH3 domain containing 2	0.012
SH3KBP1	SH3-domain kinase binding protein 1	0.012
PKM2	pyruvate kinase, muscle	0.012
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.012
SND1	staphylococcal nuclease and tudor domain containing 1	0.012
ALDOA	aldolase A, fructose-bisphosphate	0.012
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.012
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.012
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.012
SMAD7	SMAD family member 7	0.012
LAT	linker for activation of T cells	0.012
HDAC3	histone deacetylase 3	0.012
ISOC1	isochorismatase domain containing 1	0.012
CUX1	cut-like homeobox 1	0.011
ENPP5	ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)	0.011
TEF	thyrotrophic embryonic factor	0.011
EPOR	erythropoietin receptor	0.011
CLN3	ceroid-lipofuscinosis, neuronal 3	0.011
ADAP1	ArfGAP with dual PH domains 1	0.011
TM9SF4	transmembrane 9 superfamily protein member 4	0.011
CSDE1	cold shock domain containing E1, RNA-binding	0.011
FKBP5	FK506 binding protein 5	0.011
GLTPD1	glycolipid transfer protein domain containing 1	0.011
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	0.011
SPRED1	sprouty-related, EVH1 domain containing 1	0.011
PILRA	paired immunoglobin-like type 2 receptor alpha	0.011
RAB14	RAB14, member RAS oncogene family	0.011
MAPKAP1	mitogen-activated protein kinase associated protein 1	0.011
C1orf63	chromosome 1 open reading frame 63	0.010
FRS2	fibroblast growth factor receptor substrate 2	0.010
HIBCH	3-hydroxyisobutyryl-CoA hydrolase	0.010
CANX	calnexin	0.010
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.010
KIF1C	kinesin family member 1C	0.010
PDIA6	protein disulfide isomerase family A, member 6	0.010
SORBS1	sorbin and SH3 domain containing 1	0.010	Mouse
DLD	dihydrolipoamide dehydrogenase	0.010