IMP: Integrative Multi-species Prediction

Homo sapiens

209 genes annotated in human

modification dependent protein catabolic process

GO:0019941

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "modification dependent protein catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "modification dependent protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
UBC	ubiquitin C	1.000
VCP	valosin containing protein	1.000
RNF11	ring finger protein 11	1.000
XIAP	X-linked inhibitor of apoptosis	1.000	Human
TP53	tumor protein p53	1.000
CUL3	cullin 3	1.000
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	1.000
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	1.000	Yeast Worm
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	1.000
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	1.000	Human Yeast
PTK2	PTK2 protein tyrosine kinase 2	0.999	Human Mouse
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.999
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.999
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.999
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.999
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.998	Yeast
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.998	Mouse
PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	0.998	Yeast
SKP2	S-phase kinase-associated protein 2 (p45)	0.998	Mouse
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.998
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.997
SKP1	S-phase kinase-associated protein 1	0.997
PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7	0.997	Yeast
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.995
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.995
RB1	retinoblastoma 1	0.995
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.995
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	0.995	Yeast
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.994	Yeast
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.994	Yeast
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.994
PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	0.993
UBQLN1	ubiquilin 1	0.993	Human
TRIM39	tripartite motif containing 39	0.993
PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	0.992	Yeast
HSPA8	heat shock 70kDa protein 8	0.991
CUL1	cullin 1	0.991
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.991	Fly
HDAC1	histone deacetylase 1	0.990
PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	0.989	Yeast
BIRC2	baculoviral IAP repeat containing 2	0.989
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.988
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.987
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.987	Mouse Fly
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.986
PSMB2	proteasome (prosome, macropain) subunit, beta type, 2	0.984	Yeast
BTRC	beta-transducin repeat containing	0.982
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.982
RNF111	ring finger protein 111	0.982	Mouse
PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	0.981	Yeast
PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	0.981	Yeast Fly
CDK2	cyclin-dependent kinase 2	0.980
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.978
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.976
ATXN3	ataxin 3	0.973	Mouse
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.971	Yeast
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.970	Yeast
PLK1	polo-like kinase 1	0.968
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.965
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.963	Yeast
UBE3A	ubiquitin protein ligase E3A	0.962	Mouse Fly
PSMB3	proteasome (prosome, macropain) subunit, beta type, 3	0.960	Yeast
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.959
RAD23B	RAD23 homolog B (S. cerevisiae)	0.959
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.958
ANAPC4	anaphase promoting complex subunit 4	0.958
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.957
ADRM1	adhesion regulating molecule 1	0.954
ARIH2	ariadne homolog 2 (Drosophila)	0.953
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.951
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.949	Yeast
FBXW11	F-box and WD repeat domain containing 11	0.947
CCNB1	cyclin B1	0.944
SMAD2	SMAD family member 2	0.943	Human
TRAF6	TNF receptor-associated factor 6	0.942
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.940
PSMB4	proteasome (prosome, macropain) subunit, beta type, 4	0.939	Yeast
PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.939
PDCD6IP	programmed cell death 6 interacting protein	0.938
ZNRF1	zinc and ring finger 1	0.935	Mouse
ANAPC11	anaphase promoting complex subunit 11	0.932	Yeast
PSMB6	proteasome (prosome, macropain) subunit, beta type, 6	0.929	Yeast
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.922
CSNK1E	casein kinase 1, epsilon	0.921	Mouse Fly
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.920	Mouse
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.917	Worm
PSMD8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	0.916	Yeast
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.915	Yeast
TRIM43	tripartite motif containing 43	0.914
POMP	proteasome maturation protein	0.912
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.910
SMAD4	SMAD family member 4	0.909	Human
PSMB5	proteasome (prosome, macropain) subunit, beta type, 5	0.908	Yeast Mouse
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.906	Yeast
RNF126	ring finger protein 126	0.904
CCNA2	cyclin A2	0.903
BCAR1	breast cancer anti-estrogen resistance 1	0.900
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.899	Human
ANAPC7	anaphase promoting complex subunit 7	0.898
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.896
PTEN	phosphatase and tensin homolog	0.895
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.894	Human Yeast Fly
CUL5	cullin 5	0.893
UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.886	Yeast Mouse
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.879
UCHL5	ubiquitin carboxyl-terminal hydrolase L5	0.874
AMFR	autocrine motility factor receptor	0.869
FBXW7	F-box and WD repeat domain containing 7	0.867
PJA2	praja ring finger 2	0.857
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.853
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.851
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.851
NEDD8	neural precursor cell expressed, developmentally down-regulated 8	0.845
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.829
DERL1	Der1-like domain family, member 1	0.821
CDT1	chromatin licensing and DNA replication factor 1	0.821
SMAD3	SMAD family member 3	0.816	Human
HDAC6	histone deacetylase 6	0.805	Mouse
FAF2	Fas associated factor family member 2	0.802
MIB1	mindbomb homolog 1 (Drosophila)	0.801
CUL2	cullin 2	0.795	Worm
RFWD2	ring finger and WD repeat domain 2	0.793
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.787
HSPA4	heat shock 70kDa protein 4	0.786
FBXW2	F-box and WD repeat domain containing 2	0.785
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.781	Zebrafish
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.774
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.774
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.772
HDAC2	histone deacetylase 2	0.769
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.767
EPS15	epidermal growth factor receptor pathway substrate 15	0.766
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.764
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.763
CHD4	chromodomain helicase DNA binding protein 4	0.752
RNF2	ring finger protein 2	0.747
SSR1	signal sequence receptor, alpha	0.746
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.722
SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	0.721	Human Mouse
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.720	Mouse
SMAD7	SMAD family member 7	0.717
SIAH1	seven in absentia homolog 1 (Drosophila)	0.716
SNF8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.714
SELS	selenoprotein S	0.706
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.703
MARCH7	membrane-associated ring finger (C3HC4) 7	0.698
COPS6	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	0.697
BRCA1	breast cancer 1, early onset	0.696
PPP5C	protein phosphatase 5, catalytic subunit	0.692
FBXO7	F-box protein 7	0.688
UBE2M	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.685
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.680
RNF5	ring finger protein 5	0.679
ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	0.676	Human Mouse Fly
SNX9	sorting nexin 9	0.673
USP9X	ubiquitin specific peptidase 9, X-linked	0.672	Fly
SMAD5	SMAD family member 5	0.670	Human
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.655
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.651
SQSTM1	sequestosome 1	0.639
HSPA13	heat shock protein 70kDa family, member 13	0.637
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.634	Human
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.634	Human
FBXO5	F-box protein 5	0.632
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	0.631
CREBBP	CREB binding protein	0.628
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.623	Human
PSEN1	presenilin 1	0.622	Mouse
PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.613
RBL2	retinoblastoma-like 2 (p130)	0.599	Human
YY1	YY1 transcription factor	0.597
TADA3	transcriptional adaptor 3	0.592
BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	0.591	Worm Fly
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.578
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.568
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.563	Human
UBXN7	UBX domain protein 7	0.563	Yeast
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.560	Yeast
TRIM32	tripartite motif containing 32	0.558
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	0.545
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.545
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.533
SOCS1	suppressor of cytokine signaling 1	0.532	Human
ZNF207	zinc finger protein 207	0.530
UBXN1	UBX domain protein 1	0.528
EP300	E1A binding protein p300	0.527
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.519	Human
USP15	ubiquitin specific peptidase 15	0.515	Human
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.514	Human
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.513
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.510	Yeast
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.509	Human
RAD23A	RAD23 homolog A (S. cerevisiae)	0.509
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.508
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.507
FBXL15	F-box and leucine-rich repeat protein 15	0.507
DLG1	discs, large homolog 1 (Drosophila)	0.506
MKRN1	makorin ring finger protein 1	0.493
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.492
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	0.489	Yeast
FHL2	four and a half LIM domains 2	0.488
APC	adenomatous polyposis coli	0.487
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.481
PRPF6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	0.479
RNF4	ring finger protein 4	0.475
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.473	Human
RPN1	ribophorin I	0.471
SEL1L	sel-1 suppressor of lin-12-like (C. elegans)	0.465
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.464	Mouse
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.462	Rat
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.456
E2F1	E2F transcription factor 1	0.452
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.452
TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.445
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.442
FYN	FYN oncogene related to SRC, FGR, YES	0.441
MARCH5	membrane-associated ring finger (C3HC4) 5	0.437
LRRK2	leucine-rich repeat kinase 2	0.430	Mouse
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.427	Human
BBS10	Bardet-Biedl syndrome 10	0.422
BABAM1	BRISC and BRCA1 A complex member 1	0.419
TRIM5	tripartite motif containing 5	0.416	Human
AXIN1	axin 1	0.416	Mouse Rat
TRIM27	tripartite motif containing 27	0.415	Human
TRIM21	tripartite motif containing 21	0.408	Human
UBA1	ubiquitin-like modifier activating enzyme 1	0.405
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.403
ZNF496	zinc finger protein 496	0.402
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.400
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.399	Yeast Fly
CDKN3	cyclin-dependent kinase inhibitor 3	0.398
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	0.395	Yeast
ACTB	actin, beta	0.393
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.393
PRKCA	protein kinase C, alpha	0.391
MTA2	metastasis associated 1 family, member 2	0.391	Human
CDK1	cyclin-dependent kinase 1	0.387
BAG3	BCL2-associated athanogene 3	0.381
ERCC6	excision repair cross-complementing rodent repair deficiency, complementation group 6	0.380
UBASH3B	ubiquitin associated and SH3 domain containing B	0.378
ADAM15	ADAM metallopeptidase domain 15	0.377
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	0.376	Fly
BMI1	BMI1 polycomb ring finger oncogene	0.374
RNF7	ring finger protein 7	0.374
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.371
SMAD1	SMAD family member 1	0.370	Human
FBXO33	F-box protein 33	0.370
NCF2	neutrophil cytosolic factor 2	0.368
RNF168	ring finger protein 168	0.368
RNF38	ring finger protein 38	0.365
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.364
ATM	ataxia telangiectasia mutated	0.363
UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)	0.363
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.358
KLHL12	kelch-like 12 (Drosophila)	0.356	Human
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.350
ATXN1	ataxin 1	0.350
HSPA1B	heat shock 70kDa protein 1B	0.348
BCL2L1	BCL2-like 1	0.343
AR	androgen receptor	0.341
DNM1	dynamin 1	0.340
ANAPC5	anaphase promoting complex subunit 5	0.340
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.338
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.336
TOPORS	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	0.334
UBE2E2	ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)	0.331
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.329	Human Yeast
CDC26	cell division cycle 26 homolog (S. cerevisiae)	0.326
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.322
UBXN6	UBX domain protein 6	0.319
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.314
RNF144B	ring finger protein 144B	0.313
FBXO3	F-box protein 3	0.309
UBE2L3	ubiquitin-conjugating enzyme E2L 3	0.308
RIPK2	receptor-interacting serine-threonine kinase 2	0.308
QKI	quaking homolog, KH domain RNA binding (mouse)	0.306
LRR1	leucine rich repeat protein 1	0.302
SH3RF1	SH3 domain containing ring finger 1	0.299	Fly
TUBB2C	tubulin, beta 2C	0.299
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.293	Human Yeast Mouse
CSNK1A1	casein kinase 1, alpha 1	0.293	Fly
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.293
PML	promyelocytic leukemia	0.292
RANBP2	RAN binding protein 2	0.290
CBX5	chromobox homolog 5	0.289
MAP2K4	mitogen-activated protein kinase kinase 4	0.288
DDB1	damage-specific DNA binding protein 1, 127kDa	0.281
RYBP	RING1 and YY1 binding protein	0.280	Fly
BIRC3	baculoviral IAP repeat containing 3	0.279	Human
RNF31	ring finger protein 31	0.278
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.277
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.276
KPNA4	karyopherin alpha 4 (importin alpha 3)	0.273
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.271
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.270
VHL	von Hippel-Lindau tumor suppressor	0.269
CCNB2	cyclin B2	0.268
NCF1	neutrophil cytosolic factor 1	0.267
NSFL1C	NSFL1 (p97) cofactor (p47)	0.266	Yeast
PCGF2	polycomb group ring finger 2	0.262
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.257
MTDH	metadherin	0.257
KEAP1	kelch-like ECH-associated protein 1	0.257	Human
FAF1	Fas (TNFRSF6) associated factor 1	0.251
FBXW5	F-box and WD repeat domain containing 5	0.250
PIAS4	protein inhibitor of activated STAT, 4	0.250
LNX1	ligand of numb-protein X 1	0.244	Mouse
KCTD10	potassium channel tetramerisation domain containing 10	0.244	Human
HUWE1	HECT, UBA and WWE domain containing 1	0.244	Human Yeast
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.240
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.239
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.238
RNF14	ring finger protein 14	0.237
BAG2	BCL2-associated athanogene 2	0.236
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.235
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.234
SORBS3	sorbin and SH3 domain containing 3	0.234
RNF10	ring finger protein 10	0.233
IER3	immediate early response 3	0.232
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.232
DAXX	death-domain associated protein	0.230
MYST2	MYST histone acetyltransferase 2	0.228	Human
TRAF2	TNF receptor-associated factor 2	0.228
MBD3	methyl-CpG binding domain protein 3	0.227
PARP1	poly (ADP-ribose) polymerase 1	0.224
IQGAP1	IQ motif containing GTPase activating protein 1	0.223
VTA1	Vps20-associated 1 homolog (S. cerevisiae)	0.222
BFAR	bifunctional apoptosis regulator	0.221
VPS28	vacuolar protein sorting 28 homolog (S. cerevisiae)	0.219
SLX1B	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	0.218
PPME1	protein phosphatase methylesterase 1	0.218
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.215
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.213
LPXN	leupaxin	0.212	Human
ADRBK1	adrenergic, beta, receptor kinase 1	0.212
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.208
SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.208
USP38	ubiquitin specific peptidase 38	0.204
ATF3	activating transcription factor 3	0.204
NCAM1	neural cell adhesion molecule 1	0.203
FBXO4	F-box protein 4	0.202
CCDC6	coiled-coil domain containing 6	0.202
ZYG11B	zyg-11 homolog B (C. elegans)	0.201
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.199
TRIM33	tripartite motif containing 33	0.199
HERC2	hect domain and RLD 2	0.198
SIRT2	sirtuin 2	0.198
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.198
HSPA1A	heat shock 70kDa protein 1A	0.198
CDK17	cyclin-dependent kinase 17	0.198
DERL2	Der1-like domain family, member 2	0.197
HSPB1	heat shock 27kDa protein 1	0.196
ANAPC16	anaphase promoting complex subunit 16	0.196
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.195	Human
TSG101	tumor susceptibility gene 101	0.194
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.194	Human
DNM2	dynamin 2	0.194
CANX	calnexin	0.193
COPS8	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)	0.193
SKIL	SKI-like oncogene	0.193
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.192
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.192
CHFR	checkpoint with forkhead and ring finger domains	0.191
FAM8A1	family with sequence similarity 8, member A1	0.190
RBBP5	retinoblastoma binding protein 5	0.190
TRAF1	TNF receptor-associated factor 1	0.190
PCM1	pericentriolar material 1	0.190
TFDP1	transcription factor Dp-1	0.189
GFM1	G elongation factor, mitochondrial 1	0.186
HIPK3	homeodomain interacting protein kinase 3	0.186
C11orf58	chromosome 11 open reading frame 58	0.186
DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	0.186
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.185
SENP3	SUMO1/sentrin/SMT3 specific peptidase 3	0.185
UBQLN4	ubiquilin 4	0.185
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.184	Mouse
UBA3	ubiquitin-like modifier activating enzyme 3	0.184
SPOP	speckle-type POZ protein	0.184
AXIN2	axin 2	0.183
TRADD	TNFRSF1A-associated via death domain	0.183
ANKRD13A	ankyrin repeat domain 13A	0.182
SOCS2	suppressor of cytokine signaling 2	0.181	Human
DAPK1	death-associated protein kinase 1	0.181
CLOCK	clock homolog (mouse)	0.179	Mouse
RBL1	retinoblastoma-like 1 (p107)	0.179	Human
JUN	jun proto-oncogene	0.179
SNAI1	snail homolog 1 (Drosophila)	0.178
CCND1	cyclin D1	0.178
BTBD10	BTB (POZ) domain containing 10	0.178
TRIM23	tripartite motif containing 23	0.178
TP53BP1	tumor protein p53 binding protein 1	0.177
TRAF4	TNF receptor-associated factor 4	0.177
GCLM	glutamate-cysteine ligase, modifier subunit	0.177
CSNK1D	casein kinase 1, delta	0.176	Mouse Fly
ATF5	activating transcription factor 5	0.176
TGFBR1	transforming growth factor, beta receptor 1	0.175
RNF185	ring finger protein 185	0.175	Human
KPNB1	karyopherin (importin) beta 1	0.172
PNPLA8	patatin-like phospholipase domain containing 8	0.171
SCYL2	SCY1-like 2 (S. cerevisiae)	0.170
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.170	Yeast
AURKB	aurora kinase B	0.170
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.169
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.168
MYST1	MYST histone acetyltransferase 1	0.168	Human
TPBG	trophoblast glycoprotein	0.167
EPOR	erythropoietin receptor	0.167
MAPK8	mitogen-activated protein kinase 8	0.167
DTX3L	deltex 3-like (Drosophila)	0.167
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.166
UBXN2A	UBX domain protein 2A	0.165
RNF20	ring finger protein 20	0.165
RNF114	ring finger protein 114	0.165
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.164
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.164	Mouse
CCT7	chaperonin containing TCP1, subunit 7 (eta)	0.164
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.164	Mouse
HIPK2	homeodomain interacting protein kinase 2	0.163
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.162
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.161
SLC39A7	solute carrier family 39 (zinc transporter), member 7	0.161
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.161	Mouse
DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.160	Yeast
STIP1	stress-induced-phosphoprotein 1	0.158
ANXA1	annexin A1	0.157
MYO1C	myosin IC	0.157
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.157
TH1L	TH1-like (Drosophila)	0.157
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.156	Fly
MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.154
PDIA6	protein disulfide isomerase family A, member 6	0.153
CDYL	chromodomain protein, Y-like	0.152
ADNP	activity-dependent neuroprotector homeobox	0.152
GRB2	growth factor receptor-bound protein 2	0.152
EIF2AK3	eukaryotic translation initiation factor 2-alpha kinase 3	0.152
MED21	mediator complex subunit 21	0.151
CTTN	cortactin	0.151
GFI1B	growth factor independent 1B transcription repressor	0.151
SIAH2	seven in absentia homolog 2 (Drosophila)	0.150	Human
RHOB	ras homolog gene family, member B	0.150
DDIT3	DNA-damage-inducible transcript 3	0.150
PTTG1	pituitary tumor-transforming 1	0.149
CCDC101	coiled-coil domain containing 101	0.149
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.148
STAG1	stromal antigen 1	0.148
ZNF263	zinc finger protein 263	0.147
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.147	Human
VPS37A	vacuolar protein sorting 37 homolog A (S. cerevisiae)	0.146
VPRBP	Vpr (HIV-1) binding protein	0.145
RFWD3	ring finger and WD repeat domain 3	0.145
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.145
RING1	ring finger protein 1	0.144
TERF1	telomeric repeat binding factor (NIMA-interacting) 1	0.143
PSEN2	presenilin 2 (Alzheimer disease 4)	0.143	Mouse
ANKRD17	ankyrin repeat domain 17	0.143
DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	0.143
UBE2S	ubiquitin-conjugating enzyme E2S	0.142
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.141
CSDE1	cold shock domain containing E1, RNA-binding	0.141
RLIM	ring finger protein, LIM domain interacting	0.141	Mouse
ORC4	origin recognition complex, subunit 4	0.141
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.140
SEC24B	SEC24 family, member B (S. cerevisiae)	0.139
ETF1	eukaryotic translation termination factor 1	0.139
FBXO30	F-box protein 30	0.139
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.138	Yeast
UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)	0.138
LIMS1	LIM and senescent cell antigen-like domains 1	0.137	Human
ARRB2	arrestin, beta 2	0.136
MAD2L1BP	MAD2L1 binding protein	0.136
MAPK9	mitogen-activated protein kinase 9	0.136
STAT1	signal transducer and activator of transcription 1, 91kDa	0.135
GATAD2B	GATA zinc finger domain containing 2B	0.135
DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.134
RIPK3	receptor-interacting serine-threonine kinase 3	0.133
NCK2	NCK adaptor protein 2	0.133
UNC45A	unc-45 homolog A (C. elegans)	0.133
CHMP4B	chromatin modifying protein 4B	0.132
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.132
KLHL2	kelch-like 2, Mayven (Drosophila)	0.131	Human
EIF4E	eukaryotic translation initiation factor 4E	0.131
ARNT	aryl hydrocarbon receptor nuclear translocator	0.130
ILK	integrin-linked kinase	0.130
KSR1	kinase suppressor of ras 1	0.129	Human
PRNP	prion protein	0.129
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	0.128
CD2BP2	CD2 (cytoplasmic tail) binding protein 2	0.128
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.128
FBXO11	F-box protein 11	0.128
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.127
FLNB	filamin B, beta	0.126
TXNL1	thioredoxin-like 1	0.126
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.125	Human
CDK16	cyclin-dependent kinase 16	0.125
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.125
EGFR	epidermal growth factor receptor	0.124
MED28	mediator complex subunit 28	0.124
PHF21A	PHD finger protein 21A	0.124
FEN1	flap structure-specific endonuclease 1	0.123
GLI1	GLI family zinc finger 1	0.123
EEF2	eukaryotic translation elongation factor 2	0.122
UBOX5	U-box domain containing 5	0.122
TLK1	tousled-like kinase 1	0.122	Human
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.121	Yeast
SNIP1	Smad nuclear interacting protein 1	0.120
WNK4	WNK lysine deficient protein kinase 4	0.120
LAPTM5	lysosomal protein transmembrane 5	0.118
SKA2	spindle and kinetochore associated complex subunit 2	0.118
RIC8A	resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)	0.117
SEC63	SEC63 homolog (S. cerevisiae)	0.117
CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.117
SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.116
RANGAP1	Ran GTPase activating protein 1	0.116
COPS3	COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)	0.116	Worm
WASL	Wiskott-Aldrich syndrome-like	0.116
BNIP2	BCL2/adenovirus E1B 19kDa interacting protein 2	0.115
NEURL4	neuralized homolog 4 (Drosophila)	0.115
OTUD5	OTU domain containing 5	0.115
GSK3B	glycogen synthase kinase 3 beta	0.114	Mouse Fly
MTA1	metastasis associated 1	0.114
GORAB	golgin, RAB6-interacting	0.114
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.113
MYH9	myosin, heavy chain 9, non-muscle	0.112
ERN1	endoplasmic reticulum to nucleus signaling 1	0.112
ECSIT	ECSIT homolog (Drosophila)	0.111
CHUK	conserved helix-loop-helix ubiquitous kinase	0.110
RBBP8	retinoblastoma binding protein 8	0.110
CEP55	centrosomal protein 55kDa	0.109
NCF4	neutrophil cytosolic factor 4, 40kDa	0.109
CNOT4	CCR4-NOT transcription complex, subunit 4	0.109
TINF2	TERF1 (TRF1)-interacting nuclear factor 2	0.109
HSF1	heat shock transcription factor 1	0.109
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.108
NBR1	neighbor of BRCA1 gene 1	0.107
HDAC11	histone deacetylase 11	0.107
WDR13	WD repeat domain 13	0.107
CHMP1A	chromatin modifying protein 1A	0.107
LIN28B	lin-28 homolog B (C. elegans)	0.106
USPL1	ubiquitin specific peptidase like 1	0.106
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.105
RANBP9	RAN binding protein 9	0.105
USP2	ubiquitin specific peptidase 2	0.104	Yeast
CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1	0.104
KDM1A	lysine (K)-specific demethylase 1A	0.104
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.104
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.103
BIRC8	baculoviral IAP repeat containing 8	0.103	Human
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.103
UBQLN2	ubiquilin 2	0.102	Human
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.102
MED15	mediator complex subunit 15	0.102
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.102
SOCS4	suppressor of cytokine signaling 4	0.101	Human
CHAF1B	chromatin assembly factor 1, subunit B (p60)	0.100
ARMC7	armadillo repeat containing 7	0.100
ATN1	atrophin 1	0.099
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.098
KLHDC5	kelch domain containing 5	0.098
VCL	vinculin	0.098
KLHL20	kelch-like 20 (Drosophila)	0.098
MSN	moesin	0.097	Fly
SH3KBP1	SH3-domain kinase binding protein 1	0.097
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.096
BAK1	BCL2-antagonist/killer 1	0.096
RNF41	ring finger protein 41	0.096
SP110	SP110 nuclear body protein	0.096
CRY1	cryptochrome 1 (photolyase-like)	0.096
FOXM1	forkhead box M1	0.096
TOR1AIP2	torsin A interacting protein 2	0.096
CUL4A	cullin 4A	0.096	Mouse
RARS	arginyl-tRNA synthetase	0.095
BAG6	BCL2-associated athanogene 6	0.095	Mouse
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.095
CDC7	cell division cycle 7 homolog (S. cerevisiae)	0.095
BAX	BCL2-associated X protein	0.095
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.094
PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	0.094
UBD	ubiquitin D	0.094
E2F6	E2F transcription factor 6	0.093
RCHY1	ring finger and CHY zinc finger domain containing 1	0.093
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.093
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.093
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.093
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.093
MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	0.092
SLBP	stem-loop binding protein	0.092
HTRA2	HtrA serine peptidase 2	0.092
NBN	nibrin	0.092
CCPG1	cell cycle progression 1	0.092
TUBA1A	tubulin, alpha 1a	0.091
C1D	C1D nuclear receptor corepressor	0.091
MAGEA2	melanoma antigen family A, 2	0.091
DIABLO	diablo, IAP-binding mitochondrial protein	0.091
TERF2	telomeric repeat binding factor 2	0.090	Human
DCTN4	dynactin 4 (p62)	0.090
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.089	Rat
TRIM25	tripartite motif containing 25	0.089
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.089
HOXA1	homeobox A1	0.089
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.089
C19orf39	chromosome 19 open reading frame 39	0.089
SEC31A	SEC31 homolog A (S. cerevisiae)	0.088
HIST1H4A	histone cluster 1, H4a	0.088
STRN3	striatin, calmodulin binding protein 3	0.088
EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	0.088
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.088
PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A	0.088
PHF20L1	PHD finger protein 20-like 1	0.087
PAWR	PRKC, apoptosis, WT1, regulator	0.087
SGOL2	shugoshin-like 2 (S. pombe)	0.087
STAMBP	STAM binding protein	0.087
PPIG	peptidylprolyl isomerase G (cyclophilin G)	0.086
RAB21	RAB21, member RAS oncogene family	0.086
ZYX	zyxin	0.085
ZNF746	zinc finger protein 746	0.085
RNF26	ring finger protein 26	0.085
UBE2J1	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)	0.085
NKAP	NFKB activating protein	0.085
COMMD6	COMM domain containing 6	0.085
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.084
SLC35B1	solute carrier family 35, member B1	0.084
NUDCD3	NudC domain containing 3	0.083
TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	0.083
RPL11	ribosomal protein L11	0.083
MYO6	myosin VI	0.083
PLAA	phospholipase A2-activating protein	0.083	Yeast
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.082
ANXA7	annexin A7	0.082
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.082
ZFAND5	zinc finger, AN1-type domain 5	0.082
UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	0.082
USP16	ubiquitin specific peptidase 16	0.082
TRIM41	tripartite motif containing 41	0.082	Human
RNF130	ring finger protein 130	0.081
USP25	ubiquitin specific peptidase 25	0.081
NFE2L1	nuclear factor (erythroid-derived 2)-like 1	0.081	Human
PHF20	PHD finger protein 20	0.081
HSPH1	heat shock 105kDa/110kDa protein 1	0.080
DBP	D site of albumin promoter (albumin D-box) binding protein	0.079
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.079
TUBG1	tubulin, gamma 1	0.079
TOP3A	topoisomerase (DNA) III alpha	0.078
MATK	megakaryocyte-associated tyrosine kinase	0.078	Human
DOCK1	dedicator of cytokinesis 1	0.078
FAM3A	family with sequence similarity 3, member A	0.078
PIAS1	protein inhibitor of activated STAT, 1	0.078	Mouse
EZR	ezrin	0.077	Fly
PPP6C	protein phosphatase 6, catalytic subunit	0.077
TYRP1	tyrosinase-related protein 1	0.077
MAVS	mitochondrial antiviral signaling protein	0.077
KIF5B	kinesin family member 5B	0.077
EIF1	eukaryotic translation initiation factor 1	0.077
FBXO25	F-box protein 25	0.076
BAG1	BCL2-associated athanogene	0.076
L3MBTL1	l(3)mbt-like 1 (Drosophila)	0.076
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.076
CCNE2	cyclin E2	0.076	Fly
ASF1A	ASF1 anti-silencing function 1 homolog A (S. cerevisiae)	0.076
ESR2	estrogen receptor 2 (ER beta)	0.076
SNX18	sorting nexin 18	0.075
TBC1D10A	TBC1 domain family, member 10A	0.075
KLF5	Kruppel-like factor 5 (intestinal)	0.074
MAGED1	melanoma antigen family D, 1	0.074
KIF2A	kinesin heavy chain member 2A	0.074
SNX16	sorting nexin 16	0.074
ARF4	ADP-ribosylation factor 4	0.074
YTHDF2	YTH domain family, member 2	0.074
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	0.074	Yeast
PDLIM7	PDZ and LIM domain 7 (enigma)	0.074
SPCS3	signal peptidase complex subunit 3 homolog (S. cerevisiae)	0.074
NPEPPS	aminopeptidase puromycin sensitive	0.073
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.073
KALRN	kalirin, RhoGEF kinase	0.073
NRD1	nardilysin (N-arginine dibasic convertase)	0.073
PAIP1	poly(A) binding protein interacting protein 1	0.073
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.072
KIAA0232	KIAA0232	0.072
CASP8AP2	caspase 8 associated protein 2	0.072
SRCIN1	SRC kinase signaling inhibitor 1	0.072
CAND1	cullin-associated and neddylation-dissociated 1	0.072
ATP13A2	ATPase type 13A2	0.072
SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5	0.072
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.071
EEF1G	eukaryotic translation elongation factor 1 gamma	0.071
NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	0.071
SMAD9	SMAD family member 9	0.071
FEM1C	fem-1 homolog c (C. elegans)	0.071
CUL7	cullin 7	0.071
CCDC50	coiled-coil domain containing 50	0.071
DEPDC1	DEP domain containing 1	0.071
S100A4	S100 calcium binding protein A4	0.071
INO80	INO80 homolog (S. cerevisiae)	0.070
TUBB	tubulin, beta	0.070
EIF1B	eukaryotic translation initiation factor 1B	0.070
HIST2H2AC	histone cluster 2, H2ac	0.070
UBB	ubiquitin B	0.070
TOR1A	torsin family 1, member A (torsin A)	0.070
TMEM33	transmembrane protein 33	0.070
CHMP2B	chromatin modifying protein 2B	0.070
SIRT1	sirtuin 1	0.070
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	0.070
MSL2	male-specific lethal 2 homolog (Drosophila)	0.070
KLHL22	kelch-like 22 (Drosophila)	0.069
LTN1	listerin E3 ubiquitin protein ligase 1	0.069
CDKN2AIP	CDKN2A interacting protein	0.069
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.069
TXNDC11	thioredoxin domain containing 11	0.069
CD44	CD44 molecule (Indian blood group)	0.069
BRD7	bromodomain containing 7	0.068
ANAPC13	anaphase promoting complex subunit 13	0.068
ARRB1	arrestin, beta 1	0.068
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.068
HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	0.068
LMNA	lamin A/C	0.068
DDX24	DEAD (Asp-Glu-Ala-Asp) box polypeptide 24	0.068
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.068	Fly
FBXL5	F-box and leucine-rich repeat protein 5	0.068
TBP	TATA box binding protein	0.068
C12orf44	chromosome 12 open reading frame 44	0.068
NEK9	NIMA (never in mitosis gene a)- related kinase 9	0.067
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.067
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.067
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.067
WDR45	WD repeat domain 45	0.067
PTPRA	protein tyrosine phosphatase, receptor type, A	0.067
FBXO44	F-box protein 44	0.067	Human
FBXO34	F-box protein 34	0.066
DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	0.066	Human
PEX26	peroxisomal biogenesis factor 26	0.066
GNL3L	guanine nucleotide binding protein-like 3 (nucleolar)-like	0.066
CEBPE	CCAAT/enhancer binding protein (C/EBP), epsilon	0.066
USP42	ubiquitin specific peptidase 42	0.066	Human
MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.065
USP5	ubiquitin specific peptidase 5 (isopeptidase T)	0.065
DDIT4	DNA-damage-inducible transcript 4	0.065
UBE3C	ubiquitin protein ligase E3C	0.065	Yeast Worm
LIN9	lin-9 homolog (C. elegans)	0.065
TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)	0.065
NUB1	negative regulator of ubiquitin-like proteins 1	0.065
KDM4A	lysine (K)-specific demethylase 4A	0.065
POU5F1	POU class 5 homeobox 1	0.065
ING2	inhibitor of growth family, member 2	0.065
ATF7IP	activating transcription factor 7 interacting protein	0.064
E2F4	E2F transcription factor 4, p107/p130-binding	0.064
RDBP	RD RNA binding protein	0.064
PRC1	protein regulator of cytokinesis 1	0.064
PARP3	poly (ADP-ribose) polymerase family, member 3	0.064
PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase	0.064
RNF144A	ring finger protein 144A	0.064	Human
COIL	coilin	0.064