IMP: Integrative Multi-species Prediction

Homo sapiens

23 genes annotated in human

mitochondrial respiratory chain complex assembly

The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mitochondrial respiratory chain complex assembly"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "mitochondrial respiratory chain complex assembly" (in gray)

Name	Description	Probability	Func Analog Organism
NDUFS3	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	0.979
NDUFA2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa	0.938
NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	0.877
NDUFA7	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa	0.818
NDUFS7	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)	0.813
SURF1	surfeit 1	0.426
TFB1M	transcription factor B1, mitochondrial	0.416
NDUFB7	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa	0.416
NDUFS8	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)	0.407
NDUFV1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	0.297	Worm
SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.273
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.241
ECI1	enoyl-CoA delta isomerase 1	0.167
NDUFB8	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	0.165
TFB2M	transcription factor B2, mitochondrial	0.146
NDUFA9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	0.134
ICT1	immature colon carcinoma transcript 1	0.130
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.118
FASTKD2	FAST kinase domains 2	0.100
MARK3	MAP/microtubule affinity-regulating kinase 3	0.097
C21orf33	chromosome 21 open reading frame 33	0.097
NDUFB10	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa	0.096
MRPL34	mitochondrial ribosomal protein L34	0.094
IDH3G	isocitrate dehydrogenase 3 (NAD+) gamma	0.087
NDUFS4	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)	0.084
COX11	COX11 cytochrome c oxidase assembly homolog (yeast)	0.081
HIGD2A	HIG1 hypoxia inducible domain family, member 2A	0.072
NFYA	nuclear transcription factor Y, alpha	0.071
SAMM50	sorting and assembly machinery component 50 homolog (S. cerevisiae)	0.067
SYT11	synaptotagmin XI	0.066
PCCB	propionyl CoA carboxylase, beta polypeptide	0.064
MRPS9	mitochondrial ribosomal protein S9	0.062
TSFM	Ts translation elongation factor, mitochondrial	0.061
NDUFA10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa	0.049
COQ9	coenzyme Q9 homolog (S. cerevisiae)	0.049
SDHB	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	0.049
C8orf38	chromosome 8 open reading frame 38	0.049
TMEM70	transmembrane protein 70	0.048
MRPL23	mitochondrial ribosomal protein L23	0.044
NFS1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)	0.043
HSPA1B	heat shock 70kDa protein 1B	0.043
MRPL35	mitochondrial ribosomal protein L35	0.042
LIAS	lipoic acid synthetase	0.042
MRPS25	mitochondrial ribosomal protein S25	0.041
COX6C	cytochrome c oxidase subunit VIc	0.039
NSA2	NSA2 ribosome biogenesis homolog (S. cerevisiae)	0.039
TSC2	tuberous sclerosis 2	0.038
MTERFD1	MTERF domain containing 1	0.037
NDUFA1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa	0.037
FASTKD1	FAST kinase domains 1	0.036
C20orf7	chromosome 20 open reading frame 7	0.035
CHCHD4	coiled-coil-helix-coiled-coil-helix domain containing 4	0.035
C18orf55	chromosome 18 open reading frame 55	0.034
SFXN4	sideroflexin 4	0.032
MARK2	MAP/microtubule affinity-regulating kinase 2	0.032
GCDH	glutaryl-CoA dehydrogenase	0.032
GMPR2	guanosine monophosphate reductase 2	0.032
GFM1	G elongation factor, mitochondrial 1	0.030
SUPV3L1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.030
KIF5B	kinesin family member 5B	0.030
IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	0.030
C3orf1	chromosome 3 open reading frame 1	0.029
TOMM20	translocase of outer mitochondrial membrane 20 homolog (yeast)	0.029
ECH1	enoyl CoA hydratase 1, peroxisomal	0.029
MRPL24	mitochondrial ribosomal protein L24	0.029
ETFB	electron-transfer-flavoprotein, beta polypeptide	0.028
SDR39U1	short chain dehydrogenase/reductase family 39U, member 1	0.027
NDUFA8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa	0.026
GRHPR	glyoxylate reductase/hydroxypyruvate reductase	0.025
MECR	mitochondrial trans-2-enoyl-CoA reductase	0.025
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.025
ARL2	ADP-ribosylation factor-like 2	0.025
EID3	EP300 interacting inhibitor of differentiation 3	0.024
SPRED1	sprouty-related, EVH1 domain containing 1	0.024
FAM92A1	family with sequence similarity 92, member A1	0.024
METTL17	methyltransferase like 17	0.023
MRPL1	mitochondrial ribosomal protein L1	0.023
NARS2	asparaginyl-tRNA synthetase 2, mitochondrial (putative)	0.022
NDUFAF1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1	0.022
MPRIP	myosin phosphatase Rho interacting protein	0.022
NUP35	nucleoporin 35kDa	0.022
GOT1	glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)	0.022
UQCRC2	ubiquinol-cytochrome c reductase core protein II	0.021
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.021
OTUD6B	OTU domain containing 6B	0.021
DCXR	dicarbonyl/L-xylulose reductase	0.021
LUC7L3	LUC7-like 3 (S. cerevisiae)	0.020
CYCS	cytochrome c, somatic	0.020
C4orf14	chromosome 4 open reading frame 14	0.020
UQCRB	ubiquinol-cytochrome c reductase binding protein	0.019	Yeast
TECR	trans-2,3-enoyl-CoA reductase	0.019
BCKDHA	branched chain keto acid dehydrogenase E1, alpha polypeptide	0.019
NPRL2	nitrogen permease regulator-like 2 (S. cerevisiae)	0.019
MRPL30	mitochondrial ribosomal protein L30	0.019
RALGPS2	Ral GEF with PH domain and SH3 binding motif 2	0.018
RRP15	ribosomal RNA processing 15 homolog (S. cerevisiae)	0.018
MRPL32	mitochondrial ribosomal protein L32	0.018
LYRM7	Lyrm7 homolog (mouse)	0.018
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.018
MGST3	microsomal glutathione S-transferase 3	0.017
MIPEP	mitochondrial intermediate peptidase	0.017
C1orf123	chromosome 1 open reading frame 123	0.017
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.017
SLC25A11	solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11	0.017
MFSD3	major facilitator superfamily domain containing 3	0.017
ESF1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	0.017
MRPL50	mitochondrial ribosomal protein L50	0.017
WDR92	WD repeat domain 92	0.017
BAD	BCL2-associated agonist of cell death	0.016
EDC3	enhancer of mRNA decapping 3 homolog (S. cerevisiae)	0.016
ATP5H	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d	0.016
ANAPC7	anaphase promoting complex subunit 7	0.016
MRPS11	mitochondrial ribosomal protein S11	0.016
EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	0.016
TJP2	tight junction protein 2 (zona occludens 2)	0.016
CISD1	CDGSH iron sulfur domain 1	0.016
PMVK	phosphomevalonate kinase	0.016
COQ3	coenzyme Q3 homolog, methyltransferase (S. cerevisiae)	0.016
TSEN2	tRNA splicing endonuclease 2 homolog (S. cerevisiae)	0.016
NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	0.015
MBD1	methyl-CpG binding domain protein 1	0.015
TRAPPC2L	trafficking protein particle complex 2-like	0.015
FRMD6	FERM domain containing 6	0.015
PTCD3	Pentatricopeptide repeat domain 3	0.015
C6orf203	chromosome 6 open reading frame 203	0.015
FAHD1	fumarylacetoacetate hydrolase domain containing 1	0.015
RG9MTD1	RNA (guanine-9-) methyltransferase domain containing 1	0.015
OXNAD1	oxidoreductase NAD-binding domain containing 1	0.014
PET112L	PET112-like (yeast)	0.014
FAM82A2	family with sequence similarity 82, member A2	0.014
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.014
C6orf108	chromosome 6 open reading frame 108	0.014
ZC3H8	zinc finger CCCH-type containing 8	0.014
C14orf126	chromosome 14 open reading frame 126	0.014
PCSK5	proprotein convertase subtilisin/kexin type 5	0.014
FOXRED1	FAD-dependent oxidoreductase domain containing 1	0.014
PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1	0.014
COQ7	coenzyme Q7 homolog, ubiquinone (yeast)	0.013
PMS2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	0.013
COX16	COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)	0.013
C18orf19	chromosome 18 open reading frame 19	0.013
EIF2B3	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	0.013
RAI14	retinoic acid induced 14	0.013
PREPL	prolyl endopeptidase-like	0.013
CMC1	COX assembly mitochondrial protein homolog (S. cerevisiae)	0.013
LNX1	ligand of numb-protein X 1	0.013
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.013
GPX4	glutathione peroxidase 4 (phospholipid hydroperoxidase)	0.013
MUTYH	mutY homolog (E. coli)	0.012
CRLS1	cardiolipin synthase 1	0.012
SLC25A12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12	0.012
UBA1	ubiquitin-like modifier activating enzyme 1	0.012
YAP1	Yes-associated protein 1	0.012
BCLAF1	BCL2-associated transcription factor 1	0.012
SCO1	SCO cytochrome oxidase deficient homolog 1 (yeast)	0.012
HAGH	hydroxyacylglutathione hydrolase	0.012
SRP14	signal recognition particle 14kDa (homologous Alu RNA binding protein)	0.011
HDAC4	histone deacetylase 4	0.011
SPAG7	sperm associated antigen 7	0.011
MPHOSPH10	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)	0.011
CCDC58	coiled-coil domain containing 58	0.011
RPP14	ribonuclease P/MRP 14kDa subunit	0.011
MRPL21	mitochondrial ribosomal protein L21	0.011
UROS	uroporphyrinogen III synthase	0.011
MED11	mediator complex subunit 11	0.011
NDUFC2	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa	0.011
PFKM	phosphofructokinase, muscle	0.011
DIS3L	DIS3 mitotic control homolog (S. cerevisiae)-like	0.011
PET117	cytochrome c oxidase assembly factor-like	0.011
TGS1	trimethylguanosine synthase 1	0.011
HDAC7	histone deacetylase 7	0.011
MRPS5	mitochondrial ribosomal protein S5	0.011
FARS2	phenylalanyl-tRNA synthetase 2, mitochondrial	0.011
COQ6	coenzyme Q6 homolog, monooxygenase (S. cerevisiae)	0.011
C7orf44	chromosome 7 open reading frame 44	0.011
GTPBP8	GTP-binding protein 8 (putative)	0.011
FAHD2A	fumarylacetoacetate hydrolase domain containing 2A	0.011
ACAT1	acetyl-CoA acetyltransferase 1	0.011
DPH5	DPH5 homolog (S. cerevisiae)	0.011
PIGW	phosphatidylinositol glycan anchor biosynthesis, class W	0.010
PIGU	phosphatidylinositol glycan anchor biosynthesis, class U	0.010
NDUFB5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa	0.010
TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)	0.010
MRPL27	mitochondrial ribosomal protein L27	0.010
CHCHD7	coiled-coil-helix-coiled-coil-helix domain containing 7	0.010
HRSP12	heat-responsive protein 12	0.010
MRPS18B	mitochondrial ribosomal protein S18B	0.010
TPD52L1	tumor protein D52-like 1	0.010
CUTC	cutC copper transporter homolog (E. coli)	0.010
MRPL51	mitochondrial ribosomal protein L51	0.010
C9orf123	chromosome 9 open reading frame 123	0.010
YARS2	tyrosyl-tRNA synthetase 2, mitochondrial	0.010
ZNF639	zinc finger protein 639	0.010
KIAA0930	KIAA0930	0.010
USE1	unconventional SNARE in the ER 1 homolog (S. cerevisiae)	0.010