IMP
Process View
regulation of heart induction
Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.
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Click on a gene's description to view its network relationships with genes known to be involved in "regulation of heart induction"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 1.000 | ||
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.999 | Fly | |
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.996 | Fly | |
| CSNK1E | casein kinase 1, epsilon | 0.995 | ||
| SP1 | Sp1 transcription factor | 0.986 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.981 | ||
| FOXD3 | forkhead box D3 | 0.980 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.951 | ||
| AXIN1 | axin 1 | 0.935 | ||
| SOX10 | SRY (sex determining region Y)-box 10 | 0.859 | ||
| PAX3 | paired box 3 | 0.789 | ||
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.740 | ||
| CTNNBIP1 | catenin, beta interacting protein 1 | 0.662 | ||
| APC | adenomatous polyposis coli | 0.657 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.646 | ||
| CEP164 | centrosomal protein 164kDa | 0.598 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.596 | ||
| SOX2 | SRY (sex determining region Y)-box 2 | 0.590 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.575 | ||
| WT1 | Wilms tumor 1 | 0.447 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.408 | ||
| BTRC | beta-transducin repeat containing | 0.354 | ||
| FZD1 | frizzled homolog 1 (Drosophila) | 0.346 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.311 | ||
| PRPF3 | PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) | 0.228 | ||
| MYST2 | MYST histone acetyltransferase 2 | 0.219 | ||
| TCF4 | transcription factor 4 | 0.215 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.215 | Fly | |
| HCFC1 | host cell factor C1 (VP16-accessory protein) | 0.206 | ||
| HMGA1 | high mobility group AT-hook 1 | 0.165 | ||
| JUP | junction plakoglobin | 0.136 | Fly | |
| CSNK1D | casein kinase 1, delta | 0.115 | ||
| FAM110C | family with sequence similarity 110, member C | 0.106 | ||
| PIK3CB | phosphoinositide-3-kinase, catalytic, beta polypeptide | 0.101 | ||
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.091 | ||
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 0.082 | ||
| POU3F3 | POU class 3 homeobox 3 | 0.076 | Human | |
| SOX21 | SRY (sex determining region Y)-box 21 | 0.076 | ||
| NKD2 | naked cuticle homolog 2 (Drosophila) | 0.075 | ||
| WDYHV1 | WDYHV motif containing 1 | 0.074 | ||
| DSP | desmoplakin | 0.074 | ||
| PSEN1 | presenilin 1 | 0.071 | ||
| AR | androgen receptor | 0.071 | ||
| FBXW11 | F-box and WD repeat domain containing 11 | 0.070 | ||
| BAHD1 | bromo adjacent homology domain containing 1 | 0.069 | ||
| MCC | mutated in colorectal cancers | 0.061 | ||
| PITX1 | paired-like homeodomain 1 | 0.060 | ||
| SMAD7 | SMAD family member 7 | 0.060 | ||
| SOX1 | SRY (sex determining region Y)-box 1 | 0.057 | ||
| NCOA2 | nuclear receptor coactivator 2 | 0.056 | ||
| TP73 | tumor protein p73 | 0.049 | ||
| OTP | orthopedia homeobox | 0.045 | ||
| CADM4 | cell adhesion molecule 4 | 0.043 | ||
| TAOK1 | TAO kinase 1 | 0.043 | ||
| FERMT2 | fermitin family member 2 | 0.042 | ||
| SOX11 | SRY (sex determining region Y)-box 11 | 0.041 | ||
| FAM110A | family with sequence similarity 110, member A | 0.040 | ||
| FZD8 | frizzled homolog 8 (Drosophila) | 0.038 | ||
| NOVA2 | neuro-oncological ventral antigen 2 | 0.038 | ||
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.037 | ||
| YAP1 | Yes-associated protein 1 | 0.036 | ||
| FOXE1 | forkhead box E1 (thyroid transcription factor 2) | 0.035 | ||
| PDX1 | pancreatic and duodenal homeobox 1 | 0.034 | ||
| EMD | emerin | 0.034 | ||
| ZBTB8A | zinc finger and BTB domain containing 8A | 0.033 | ||
| DIDO1 | death inducer-obliterator 1 | 0.033 | ||
| ASCL1 | achaete-scute complex homolog 1 (Drosophila) | 0.032 | ||
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.032 | ||
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.032 | ||
| ZBTB48 | zinc finger and BTB domain containing 48 | 0.030 | ||
| NPAS1 | neuronal PAS domain protein 1 | 0.030 | ||
| NEUROG3 | neurogenin 3 | 0.029 | ||
| PKP4 | plakophilin 4 | 0.028 | ||
| LBX1 | ladybird homeobox 1 | 0.028 | ||
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.027 | ||
| NKX2-1 | NK2 homeobox 1 | 0.026 | ||
| TLX2 | T-cell leukemia homeobox 2 | 0.026 | ||
| SNIP1 | Smad nuclear interacting protein 1 | 0.026 | ||
| FGF3 | fibroblast growth factor 3 | 0.026 | ||
| ERBB2IP | erbb2 interacting protein | 0.026 | ||
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.026 | ||
| C16orf48 | chromosome 16 open reading frame 48 | 0.026 | ||
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.026 | ||
| HES1 | hairy and enhancer of split 1, (Drosophila) | 0.025 | ||
| DPPA2 | developmental pluripotency associated 2 | 0.025 | ||
| POU3F4 | POU class 3 homeobox 4 | 0.025 | Human | |
| DSG2 | desmoglein 2 | 0.025 | ||
| HTT | huntingtin | 0.025 | ||
| HOXB13 | homeobox B13 | 0.025 | ||
| EP300 | E1A binding protein p300 | 0.024 | ||
| HIC1 | hypermethylated in cancer 1 | 0.024 | ||
| KLHL12 | kelch-like 12 (Drosophila) | 0.024 | ||
| POU3F2 | POU class 3 homeobox 2 | 0.023 | Human | |
| ZBTB17 | zinc finger and BTB domain containing 17 | 0.023 | ||
| ZNF512B | zinc finger protein 512B | 0.023 | ||
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.023 | ||
| EZR | ezrin | 0.023 | ||
| EVX1 | even-skipped homeobox 1 | 0.023 | ||
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.023 | ||
| LHX1 | LIM homeobox 1 | 0.022 | ||
| SIX6 | SIX homeobox 6 | 0.021 | ||
| OCLN | occludin | 0.020 | ||
| NCSTN | nicastrin | 0.020 | ||
| HNF1A | HNF1 homeobox A | 0.020 | ||
| POU3F1 | POU class 3 homeobox 1 | 0.020 | Human | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.020 | ||
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa | 0.019 | ||
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.019 | ||
| DRD4 | dopamine receptor D4 | 0.019 | ||
| TNFAIP8L1 | tumor necrosis factor, alpha-induced protein 8-like 1 | 0.019 | ||
| FOXO1 | forkhead box O1 | 0.019 | ||
| NHLH2 | nescient helix loop helix 2 | 0.019 | ||
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.018 | ||
| MDFI | MyoD family inhibitor | 0.018 | ||
| EMX1 | empty spiracles homeobox 1 | 0.018 | ||
| ETS2 | v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) | 0.018 | ||
| FOXO3 | forkhead box O3 | 0.017 | ||
| DAXX | death-domain associated protein | 0.017 | ||
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.017 | ||
| WNT3 | wingless-type MMTV integration site family, member 3 | 0.017 | ||
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.017 | ||
| LHX5 | LIM homeobox 5 | 0.017 | ||
| OLIG2 | oligodendrocyte lineage transcription factor 2 | 0.017 | ||
| SFRP5 | secreted frizzled-related protein 5 | 0.017 | ||
| UTF1 | undifferentiated embryonic cell transcription factor 1 | 0.016 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.016 | ||
| PAX2 | paired box 2 | 0.016 | ||
| ALX3 | ALX homeobox 3 | 0.016 | ||
| NKX2-8 | NK2 homeobox 8 | 0.016 | ||
| GSC2 | goosecoid homeobox 2 | 0.016 | ||
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.016 | ||
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 0.016 | ||
| HES2 | hairy and enhancer of split 2 (Drosophila) | 0.016 | ||
| FOXB1 | forkhead box B1 | 0.016 | ||
| CREBBP | CREB binding protein | 0.016 | ||
| DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.016 | Fly | |
| HTR2C | 5-hydroxytryptamine (serotonin) receptor 2C | 0.016 | ||
| HOXD12 | homeobox D12 | 0.016 | ||
| PRDM8 | PR domain containing 8 | 0.016 | ||
| RAB5B | RAB5B, member RAS oncogene family | 0.015 | ||
| RAX | retina and anterior neural fold homeobox | 0.015 | ||
| FOXL1 | forkhead box L1 | 0.015 | ||
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.015 | ||
| HOXC8 | homeobox C8 | 0.015 | ||
| TBX5 | T-box 5 | 0.015 | ||
| NKX6-1 | NK6 homeobox 1 | 0.015 | ||
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.015 | ||
| CD22 | CD22 molecule | 0.015 | ||
| WNT10A | wingless-type MMTV integration site family, member 10A | 0.015 | ||
| PAX6 | paired box 6 | 0.015 | ||
| PTK7 | PTK7 protein tyrosine kinase 7 | 0.015 | ||
| LMO1 | LIM domain only 1 (rhombotin 1) | 0.015 | ||
| PYY | peptide YY | 0.014 | ||
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) | 0.014 | ||
| DPPA4 | developmental pluripotency associated 4 | 0.014 | ||
| DDI1 | DNA-damage inducible 1 homolog 1 (S. cerevisiae) | 0.014 | ||
| ZNF408 | zinc finger protein 408 | 0.014 | ||
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | 0.014 | ||
| PRICKLE1 | prickle homolog 1 (Drosophila) | 0.014 | ||
| FZD2 | frizzled homolog 2 (Drosophila) | 0.014 | ||
| DLX4 | distal-less homeobox 4 | 0.014 | ||
| PAX5 | paired box 5 | 0.014 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.014 | ||
| ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | 0.014 | ||
| PITX2 | paired-like homeodomain 2 | 0.013 | ||
| POU4F1 | POU class 4 homeobox 1 | 0.013 | Human | |
| POU4F3 | POU class 4 homeobox 3 | 0.013 | Human | |
| ARHGEF19 | Rho guanine nucleotide exchange factor (GEF) 19 | 0.013 | ||
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled) | 0.013 | ||
| HOXD3 | homeobox D3 | 0.013 | ||
| CLASRP | CLK4-associating serine/arginine rich protein | 0.013 | ||
| CALCA | calcitonin-related polypeptide alpha | 0.013 | ||
| NEUROD2 | neurogenic differentiation 2 | 0.013 | ||
| FOXA1 | forkhead box A1 | 0.013 | ||
| HOXD9 | homeobox D9 | 0.013 | ||
| NFYA | nuclear transcription factor Y, alpha | 0.013 | ||
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 | 0.013 | ||
| NRTN | neurturin | 0.013 | ||
| PER1 | period homolog 1 (Drosophila) | 0.013 | ||
| RABAC1 | Rab acceptor 1 (prenylated) | 0.012 | ||
| SIM2 | single-minded homolog 2 (Drosophila) | 0.012 | ||
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.012 | ||
| FOXA2 | forkhead box A2 | 0.012 | ||
| TRIM9 | tripartite motif containing 9 | 0.012 | ||
| CCDC92 | coiled-coil domain containing 92 | 0.012 | ||
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.012 | ||
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.012 | ||
| GATA5 | GATA binding protein 5 | 0.012 | ||
| PRDM13 | PR domain containing 13 | 0.012 | ||
| BHLHE23 | basic helix-loop-helix family, member e23 | 0.012 | ||
| RADIL | Ras association and DIL domains | 0.012 | ||
| PXN | paxillin | 0.012 | ||
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.012 | ||
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.012 | ||
| ATN1 | atrophin 1 | 0.012 | ||
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 | 0.012 | ||
| MAPT | microtubule-associated protein tau | 0.012 | ||
| PGR | progesterone receptor | 0.012 | ||
| GCM2 | glial cells missing homolog 2 (Drosophila) | 0.011 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.011 | ||
| PAX8 | paired box 8 | 0.011 | ||
| PKP2 | plakophilin 2 | 0.011 | ||
| LEF1 | lymphoid enhancer-binding factor 1 | 0.011 | ||
| SSTR5 | somatostatin receptor 5 | 0.011 | ||
| GALR1 | galanin receptor 1 | 0.011 | ||
| PNOC | prepronociceptin | 0.011 | ||
| NELL1 | NEL-like 1 (chicken) | 0.011 | ||
| RBM11 | RNA binding motif protein 11 | 0.011 | ||
| DLX2 | distal-less homeobox 2 | 0.011 | ||
| POMC | proopiomelanocortin | 0.011 | ||
| FSCN2 | fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) | 0.011 | ||
| GBX2 | gastrulation brain homeobox 2 | 0.011 | ||
| HOXD13 | homeobox D13 | 0.011 | ||
| TNIK | TRAF2 and NCK interacting kinase | 0.011 | ||
| EYA2 | eyes absent homolog 2 (Drosophila) | 0.011 | ||
| CDX2 | caudal type homeobox 2 | 0.011 | ||
| HOXD11 | homeobox D11 | 0.011 | ||
| ELAVL2 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) | 0.011 | ||
| B4GALNT2 | beta-1,4-N-acetyl-galactosaminyl transferase 2 | 0.011 | ||
| IHH | Indian hedgehog | 0.011 | ||
| PAX7 | paired box 7 | 0.011 | ||
| SNF8 | SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) | 0.011 | ||
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | 0.011 | ||
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.011 | ||
| HRK | harakiri, BCL2 interacting protein (contains only BH3 domain) | 0.011 | ||
| ELL | elongation factor RNA polymerase II | 0.010 | ||
| ZIC1 | Zic family member 1 (odd-paired homolog, Drosophila) | 0.010 | ||
| DMRT1 | doublesex and mab-3 related transcription factor 1 | 0.010 | ||
| JRK | jerky homolog (mouse) | 0.010 | ||
| MPL | myeloproliferative leukemia virus oncogene | 0.010 | ||
| SIX2 | SIX homeobox 2 | 0.010 | ||
| CRLF1 | cytokine receptor-like factor 1 | 0.010 | ||
| PKP1 | plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | 0.010 | ||
| NEU4 | sialidase 4 | 0.010 | ||
| GJD2 | gap junction protein, delta 2, 36kDa | 0.010 | ||
| FAM83B | family with sequence similarity 83, member B | 0.010 | ||
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | 0.010 | ||
| VSX1 | visual system homeobox 1 | 0.010 |