Process View
Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "enzyme linked receptor protein signaling pathway"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
EGFR | epidermal growth factor receptor | 1.000 | ||
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 1.000 | Mouse Rat Fly | |
ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 1.000 | ||
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 1.000 | ||
GRB2 | growth factor receptor-bound protein 2 | 1.000 | ||
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 1.000 | Human Fly | |
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 1.000 | ||
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 1.000 | Human Rat | |
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 1.000 | ||
FYN | FYN oncogene related to SRC, FGR, YES | 1.000 | Human | |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 1.000 | ||
JUN | jun proto-oncogene | 1.000 | ||
PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 1.000 | ||
ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 1.000 | Human | |
PLCG1 | phospholipase C, gamma 1 | 1.000 | ||
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 1.000 | Mouse | |
BCAR1 | breast cancer anti-estrogen resistance 1 | 1.000 | ||
CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 1.000 | ||
CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 1.000 | Human | |
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 1.000 | ||
SMAD3 | SMAD family member 3 | 1.000 | ||
MET | met proto-oncogene (hepatocyte growth factor receptor) | 1.000 | Mouse Rat | |
LCK | lymphocyte-specific protein tyrosine kinase | 1.000 | Human | |
GRB7 | growth factor receptor-bound protein 7 | 0.999 | Human | |
FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.999 | ||
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.999 | ||
SMAD4 | SMAD family member 4 | 0.999 | ||
PTK2 | PTK2 protein tyrosine kinase 2 | 0.999 | ||
CREBBP | CREB binding protein | 0.999 | ||
ESR1 | estrogen receptor 1 | 0.998 | Rat | |
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.998 | ||
FN1 | fibronectin 1 | 0.998 | ||
SMAD2 | SMAD family member 2 | 0.998 | ||
DUSP1 | dual specificity phosphatase 1 | 0.997 | ||
MAPK8 | mitogen-activated protein kinase 8 | 0.997 | Human | |
SMAD1 | SMAD family member 1 | 0.997 | ||
SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.996 | ||
IRS1 | insulin receptor substrate 1 | 0.996 | ||
CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.996 | Mouse | |
SMAD7 | SMAD family member 7 | 0.996 | ||
PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.994 | ||
SKIL | SKI-like oncogene | 0.993 | ||
FGFR2 | fibroblast growth factor receptor 2 | 0.993 | ||
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.992 | Human | |
MAPK1 | mitogen-activated protein kinase 1 | 0.992 | ||
SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.992 | ||
GRB10 | growth factor receptor-bound protein 10 | 0.989 | ||
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.989 | ||
INSR | insulin receptor | 0.987 | ||
TGFB1 | transforming growth factor, beta 1 | 0.986 | ||
MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.985 | ||
MAPK14 | mitogen-activated protein kinase 14 | 0.985 | ||
APP | amyloid beta (A4) precursor protein | 0.985 | Mouse | |
SYK | spleen tyrosine kinase | 0.984 | Mouse | |
FGF1 | fibroblast growth factor 1 (acidic) | 0.984 | ||
FHL2 | four and a half LIM domains 2 | 0.982 | ||
NCK1 | NCK adaptor protein 1 | 0.982 | Fly | |
SOCS1 | suppressor of cytokine signaling 1 | 0.981 | Human Mouse | |
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.979 | Rat | |
SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.978 | Fly | |
SP1 | Sp1 transcription factor | 0.977 | ||
PDCD6IP | programmed cell death 6 interacting protein | 0.976 | ||
MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.974 | ||
SH3KBP1 | SH3-domain kinase binding protein 1 | 0.972 | ||
PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.971 | Human Fly | |
AR | androgen receptor | 0.969 | Mouse | |
ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.968 | Human | |
GSK3B | glycogen synthase kinase 3 beta | 0.966 | Human | |
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.959 | ||
ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.956 | ||
GHR | growth hormone receptor | 0.955 | ||
LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.955 | ||
CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.952 | Human | |
TP53 | tumor protein p53 | 0.949 | Mouse Fly | |
DLG1 | discs, large homolog 1 (Drosophila) | 0.947 | Fly | |
IGF1R | insulin-like growth factor 1 receptor | 0.946 | ||
NCK2 | NCK adaptor protein 2 | 0.942 | Fly | |
LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.942 | ||
TGFBR1 | transforming growth factor, beta receptor 1 | 0.941 | ||
SOCS3 | suppressor of cytokine signaling 3 | 0.941 | Human Mouse | |
SIRT1 | sirtuin 1 | 0.940 | ||
FGFR1 | fibroblast growth factor receptor 1 | 0.939 | ||
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.937 | ||
PRKCA | protein kinase C, alpha | 0.935 | Mouse | |
ATF2 | activating transcription factor 2 | 0.933 | Human | |
VAV1 | vav 1 guanine nucleotide exchange factor | 0.928 | ||
FLNA | filamin A, alpha | 0.924 | ||
KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.922 | ||
PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.921 | ||
NCOA1 | nuclear receptor coactivator 1 | 0.919 | ||
APC | adenomatous polyposis coli | 0.912 | ||
GAB1 | GRB2-associated binding protein 1 | 0.910 | Human Mouse | |
ATF3 | activating transcription factor 3 | 0.909 | Human | |
EP300 | E1A binding protein p300 | 0.900 | ||
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.898 | ||
WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.893 | Human | |
COL6A2 | collagen, type VI, alpha 2 | 0.891 | ||
ELN | elastin | 0.887 | ||
THBS1 | thrombospondin 1 | 0.882 | ||
LTBP2 | latent transforming growth factor beta binding protein 2 | 0.882 | Human | |
TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.876 | ||
MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.870 | ||
VEGFA | vascular endothelial growth factor A | 0.866 | ||
IRS2 | insulin receptor substrate 2 | 0.865 | Human Mouse Fly | |
TGFB3 | transforming growth factor, beta 3 | 0.864 | ||
TEK | TEK tyrosine kinase, endothelial | 0.862 | ||
PSEN1 | presenilin 1 | 0.859 | Mouse | |
MUC1 | mucin 1, cell surface associated | 0.859 | ||
KPNB1 | karyopherin (importin) beta 1 | 0.857 | ||
COL1A1 | collagen, type I, alpha 1 | 0.856 | Human | |
BMP2 | bone morphogenetic protein 2 | 0.855 | ||
PTEN | phosphatase and tensin homolog | 0.853 | Rat Fly | |
RXRA | retinoid X receptor, alpha | 0.846 | ||
TLN1 | talin 1 | 0.842 | Human | |
SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.836 | ||
NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.834 | Human Mouse | |
VAV2 | vav 2 guanine nucleotide exchange factor | 0.834 | ||
ZNF746 | zinc finger protein 746 | 0.833 | ||
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.833 | ||
PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.832 | ||
WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.818 | ||
UBASH3B | ubiquitin associated and SH3 domain containing B | 0.817 | ||
NCF1 | neutrophil cytosolic factor 1 | 0.815 | ||
RNF11 | ring finger protein 11 | 0.815 | ||
PTPRB | protein tyrosine phosphatase, receptor type, B | 0.810 | Human | |
FBN1 | fibrillin 1 | 0.808 | Mouse | |
IGFBP5 | insulin-like growth factor binding protein 5 | 0.805 | ||
PRKCZ | protein kinase C, zeta | 0.802 | ||
ACAN | aggrecan | 0.800 | ||
YAP1 | Yes-associated protein 1 | 0.795 | Human | |
AXIN1 | axin 1 | 0.788 | Mouse | |
FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.782 | ||
FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.779 | Human | |
SCHIP1 | schwannomin interacting protein 1 | 0.777 | Mouse | |
ERBB2IP | erbb2 interacting protein | 0.772 | ||
BMP1 | bone morphogenetic protein 1 | 0.769 | Fly | |
IGF2R | insulin-like growth factor 2 receptor | 0.767 | ||
MAPT | microtubule-associated protein tau | 0.766 | ||
FBLN1 | fibulin 1 | 0.764 | Human | |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.758 | ||
SNX6 | sorting nexin 6 | 0.758 | ||
CRYAB | crystallin, alpha B | 0.755 | ||
HCK | hemopoietic cell kinase | 0.754 | Human | |
IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.753 | ||
SH2D3A | SH2 domain containing 3A | 0.752 | ||
JAK2 | Janus kinase 2 | 0.750 | ||
PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.750 | Human Mouse | |
DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.747 | ||
BLNK | B-cell linker | 0.746 | ||
TENC1 | tensin like C1 domain containing phosphatase (tensin 2) | 0.745 | ||
UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.744 | ||
CSK | c-src tyrosine kinase | 0.743 | ||
SH3BP4 | SH3-domain binding protein 4 | 0.743 | ||
AXL | AXL receptor tyrosine kinase | 0.737 | Mouse | |
COL6A1 | collagen, type VI, alpha 1 | 0.735 | ||
SORBS3 | sorbin and SH3 domain containing 3 | 0.734 | ||
IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.731 | ||
RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.729 | ||
C1QA | complement component 1, q subcomponent, A chain | 0.727 | Human | |
SFN | stratifin | 0.724 | ||
BMPR1A | bone morphogenetic protein receptor, type IA | 0.723 | ||
UBE3A | ubiquitin protein ligase E3A | 0.721 | ||
DUSP6 | dual specificity phosphatase 6 | 0.715 | Zebrafish | |
CTGF | connective tissue growth factor | 0.714 | Human Mouse | |
ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.708 | Human | |
POU5F1 | POU class 5 homeobox 1 | 0.702 | ||
MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.701 | ||
SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.701 | ||
MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.700 | Mouse | |
CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.698 | ||
PAX3 | paired box 3 | 0.696 | ||
IER3 | immediate early response 3 | 0.689 | ||
EPHA2 | EPH receptor A2 | 0.688 | ||
ATXN1 | ataxin 1 | 0.687 | Mouse | |
NRP1 | neuropilin 1 | 0.687 | ||
PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.687 | ||
FBLN2 | fibulin 2 | 0.686 | Human | |
ADRB1 | adrenergic, beta-1-, receptor | 0.684 | Human | |
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.682 | ||
PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.681 | Human Fly | |
LOX | lysyl oxidase | 0.671 | ||
JUNB | jun B proto-oncogene | 0.671 | Human | |
PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.670 | ||
TNS4 | tensin 4 | 0.665 | ||
RIN1 | Ras and Rab interactor 1 | 0.664 | ||
EPOR | erythropoietin receptor | 0.663 | ||
CAV2 | caveolin 2 | 0.662 | Human Mouse | |
PECAM1 | platelet/endothelial cell adhesion molecule | 0.660 | ||
NRG1 | neuregulin 1 | 0.658 | ||
TSC2 | tuberous sclerosis 2 | 0.658 | Mouse Fly | |
ACVR1 | activin A receptor, type I | 0.656 | ||
TRIM33 | tripartite motif containing 33 | 0.654 | ||
COL1A2 | collagen, type I, alpha 2 | 0.652 | ||
TNS3 | tensin 3 | 0.651 | ||
ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.647 | ||
PXN | paxillin | 0.647 | ||
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.640 | Human | |
PTK6 | PTK6 protein tyrosine kinase 6 | 0.637 | Human | |
ARRB1 | arrestin, beta 1 | 0.635 | Human | |
TGFA | transforming growth factor, alpha | 0.633 | ||
RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.633 | Mouse Fly | |
ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.632 | Human | |
DCN | decorin | 0.631 | Human | |
FLNB | filamin B, beta | 0.626 | ||
JAG1 | jagged 1 | 0.620 | ||
IGFBP3 | insulin-like growth factor binding protein 3 | 0.617 | Human Zebrafish Mouse | |
MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.605 | ||
COL2A1 | collagen, type II, alpha 1 | 0.601 | Human | |
BTRC | beta-transducin repeat containing | 0.598 | Fly | |
WNT1 | wingless-type MMTV integration site family, member 1 | 0.597 | ||
CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.597 | ||
FSTL1 | follistatin-like 1 | 0.597 | Human Zebrafish | |
IRS4 | insulin receptor substrate 4 | 0.591 | Human Fly | |
CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.586 | ||
EZR | ezrin | 0.574 | ||
ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.572 | ||
COL3A1 | collagen, type III, alpha 1 | 0.567 | ||
DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.566 | ||
BMP4 | bone morphogenetic protein 4 | 0.565 | ||
ENG | endoglin | 0.564 | ||
NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.563 | ||
TGFB2 | transforming growth factor, beta 2 | 0.563 | ||
TPBG | trophoblast glycoprotein | 0.558 | ||
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.558 | ||
ACVR1B | activin A receptor, type IB | 0.556 | ||
MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.555 | ||
DOK4 | docking protein 4 | 0.549 | Mouse | |
BHLHE40 | basic helix-loop-helix family, member e40 | 0.545 | ||
INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.540 | ||
YES1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.537 | Human | |
JAK1 | Janus kinase 1 | 0.536 | Human Mouse | |
GH1 | growth hormone 1 | 0.534 | ||
SMAD6 | SMAD family member 6 | 0.534 | ||
MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.531 | ||
VAV3 | vav 3 guanine nucleotide exchange factor | 0.527 | ||
TBX5 | T-box 5 | 0.524 | ||
ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.522 | ||
CD2AP | CD2-associated protein | 0.515 | ||
APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.514 | ||
POU3F2 | POU class 3 homeobox 2 | 0.513 | Human | |
INHBA | inhibin, beta A | 0.505 | ||
MSX1 | msh homeobox 1 | 0.503 | Mouse | |
THBS2 | thrombospondin 2 | 0.500 | Human | |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.492 | ||
ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.489 | Mouse | |
IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.489 | ||
PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.485 | Fly | |
PDZD3 | PDZ domain containing 3 | 0.484 | ||
EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 | 0.483 | Human | |
RET | ret proto-oncogene | 0.481 | Mouse | |
EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.478 | ||
MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.477 | ||
NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.473 | ||
FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.472 | Human | |
HIPK3 | homeodomain interacting protein kinase 3 | 0.470 | Human | |
JUP | junction plakoglobin | 0.469 | ||
TCF4 | transcription factor 4 | 0.465 | ||
TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.464 | ||
BGN | biglycan | 0.461 | Human | |
PTPN23 | protein tyrosine phosphatase, non-receptor type 23 | 0.459 | Fly | |
RANBP9 | RAN binding protein 9 | 0.458 | ||
HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.455 | Mouse | |
FOXD3 | forkhead box D3 | 0.452 | Human | |
PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.448 | ||
TRIP6 | thyroid hormone receptor interactor 6 | 0.445 | Human | |
EEA1 | early endosome antigen 1 | 0.443 | ||
NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.443 | Human Mouse | |
SOX9 | SRY (sex determining region Y)-box 9 | 0.441 | Human Mouse | |
FGF7 | fibroblast growth factor 7 | 0.441 | ||
BAG3 | BCL2-associated athanogene 3 | 0.440 | ||
MPDZ | multiple PDZ domain protein | 0.439 | ||
GAS6 | growth arrest-specific 6 | 0.438 | Mouse | |
TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.438 | ||
APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.438 | ||
VEGFC | vascular endothelial growth factor C | 0.433 | Human Mouse Rat | |
EFTUD2 | elongation factor Tu GTP binding domain containing 2 | 0.432 | ||
NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.430 | Human | |
UBC | ubiquitin C | 0.427 | ||
CD248 | CD248 molecule, endosialin | 0.419 | ||
LRP6 | low density lipoprotein receptor-related protein 6 | 0.418 | Human | |
SFRP4 | secreted frizzled-related protein 4 | 0.416 | ||
DNM2 | dynamin 2 | 0.412 | ||
MCRS1 | microspherule protein 1 | 0.410 | ||
PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.410 | ||
WNT2 | wingless-type MMTV integration site family member 2 | 0.410 | Human | |
MLL | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) | 0.407 | ||
SRCIN1 | SRC kinase signaling inhibitor 1 | 0.406 | ||
KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.406 | ||
EPAS1 | endothelial PAS domain protein 1 | 0.405 | ||
BMP7 | bone morphogenetic protein 7 | 0.404 | ||
CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.403 | Human | |
SH2B1 | SH2B adaptor protein 1 | 0.402 | Fly | |
IL4R | interleukin 4 receptor | 0.400 | ||
LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.398 | ||
TBX2 | T-box 2 | 0.392 | ||
ABI2 | abl-interactor 2 | 0.391 | ||
RANBP2 | RAN binding protein 2 | 0.390 | Fly | |
LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.390 | Human | |
SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.389 | ||
CD44 | CD44 molecule (Indian blood group) | 0.389 | ||
EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.389 | ||
MMP11 | matrix metallopeptidase 11 (stromelysin 3) | 0.388 | Fly | |
PUM2 | pumilio homolog 2 (Drosophila) | 0.387 | Fly | |
RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.383 | ||
CREB1 | cAMP responsive element binding protein 1 | 0.381 | Rat | |
PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | 0.380 | ||
PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | 0.377 | ||
PRELP | proline/arginine-rich end leucine-rich repeat protein | 0.377 | ||
SOX11 | SRY (sex determining region Y)-box 11 | 0.376 | ||
SNAI1 | snail homolog 1 (Drosophila) | 0.376 | ||
ADAM12 | ADAM metallopeptidase domain 12 | 0.374 | Human | |
ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.374 | ||
NOTCH3 | notch 3 | 0.374 | ||
SKP1 | S-phase kinase-associated protein 1 | 0.371 | Fly | |
MYO1C | myosin IC | 0.370 | ||
AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.369 | ||
NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 | 0.368 | ||
COL5A1 | collagen, type V, alpha 1 | 0.367 | Human | |
CSF1 | colony stimulating factor 1 (macrophage) | 0.367 | ||
NGF | nerve growth factor (beta polypeptide) | 0.367 | Human | |
NUP153 | nucleoporin 153kDa | 0.365 | Fly | |
KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.364 | ||
CHRD | chordin | 0.364 | ||
GDF5 | growth differentiation factor 5 | 0.363 | Human Mouse | |
CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 | 0.362 | ||
HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.361 | ||
TSG101 | tumor susceptibility gene 101 | 0.360 | ||
FZD7 | frizzled homolog 7 (Drosophila) | 0.359 | ||
SNF8 | SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) | 0.359 | ||
ANGPTL2 | angiopoietin-like 2 | 0.357 | Human | |
MXRA5 | matrix-remodelling associated 5 | 0.354 | ||
DOCK7 | dedicator of cytokinesis 7 | 0.354 | ||
SPRR2A | small proline-rich protein 2A | 0.351 | ||
COL13A1 | collagen, type XIII, alpha 1 | 0.350 | ||
SOCS5 | suppressor of cytokine signaling 5 | 0.348 | ||
SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.344 | ||
HDAC7 | histone deacetylase 7 | 0.344 | ||
SNTA1 | syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) | 0.343 | ||
CISH | cytokine inducible SH2-containing protein | 0.342 | Human | |
STAT5A | signal transducer and activator of transcription 5A | 0.341 | Human Mouse | |
PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.340 | ||
ARHGAP5 | Rho GTPase activating protein 5 | 0.339 | ||
QKI | quaking homolog, KH domain RNA binding (mouse) | 0.339 | ||
ETS2 | v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) | 0.337 | Fly | |
ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.337 | Mouse | |
LAMB1 | laminin, beta 1 | 0.336 | ||
IL1R1 | interleukin 1 receptor, type I | 0.335 | ||
MED28 | mediator complex subunit 28 | 0.335 | ||
ANGPT2 | angiopoietin 2 | 0.333 | ||
BLK | B lymphoid tyrosine kinase | 0.332 | Human | |
STAT5B | signal transducer and activator of transcription 5B | 0.332 | ||
TFF1 | trefoil factor 1 | 0.330 | ||
SQSTM1 | sequestosome 1 | 0.328 | ||
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.327 | ||
ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | 0.324 | Human | |
FGA | fibrinogen alpha chain | 0.323 | ||
CSNK1G3 | casein kinase 1, gamma 3 | 0.322 | ||
ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.321 | ||
TMEM173 | transmembrane protein 173 | 0.321 | ||
NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.320 | ||
RIN2 | Ras and Rab interactor 2 | 0.320 | ||
GDA | guanine deaminase | 0.317 | ||
APOA1 | apolipoprotein A-I | 0.317 | ||
BCR | breakpoint cluster region | 0.313 | ||
BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.312 | ||
BTK | Bruton agammaglobulinemia tyrosine kinase | 0.312 | Human | |
RAB1A | RAB1A, member RAS oncogene family | 0.310 | ||
CDK6 | cyclin-dependent kinase 6 | 0.310 | ||
CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.308 | ||
STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.307 | Fly | |
SFRP1 | secreted frizzled-related protein 1 | 0.307 | Mouse | |
ANXA1 | annexin A1 | 0.307 | ||
SMN1 | survival of motor neuron 1, telomeric | 0.306 | ||
SNX1 | sorting nexin 1 | 0.304 | Human | |
IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.302 | ||
TM4SF1 | transmembrane 4 L six family member 1 | 0.301 | ||
CTBP1 | C-terminal binding protein 1 | 0.300 | ||
TRAF4 | TNF receptor-associated factor 4 | 0.298 | ||
TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.297 | ||
FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.296 | ||
COL4A1 | collagen, type IV, alpha 1 | 0.294 | ||
ITIH5 | inter-alpha (globulin) inhibitor H5 | 0.293 | ||
PDGFC | platelet derived growth factor C | 0.292 | ||
FGF18 | fibroblast growth factor 18 | 0.292 | Human | |
PTRF | polymerase I and transcript release factor | 0.289 | ||
PAX8 | paired box 8 | 0.289 | ||
FGF2 | fibroblast growth factor 2 (basic) | 0.288 | ||
SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.288 | ||
IL12RB2 | interleukin 12 receptor, beta 2 | 0.287 | Human | |
GAB2 | GRB2-associated binding protein 2 | 0.283 | ||
CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.283 | ||
CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.283 | ||
PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.282 | ||
WISP1 | WNT1 inducible signaling pathway protein 1 | 0.282 | Human | |
PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.282 | ||
IGFBP6 | insulin-like growth factor binding protein 6 | 0.282 | Human | |
MAP2K2 | mitogen-activated protein kinase kinase 2 | 0.279 | ||
KLF5 | Kruppel-like factor 5 (intestinal) | 0.279 | ||
RHOB | ras homolog gene family, member B | 0.278 | ||
ARRDC3 | arrestin domain containing 3 | 0.278 | ||
HSPB2 | heat shock 27kDa protein 2 | 0.277 | ||
SLA | Src-like-adaptor | 0.276 | Human | |
PBK | PDZ binding kinase | 0.274 | ||
ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.274 | ||
TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.273 | Mouse | |
IRF2BP1 | interferon regulatory factor 2 binding protein 1 | 0.273 | ||
ITGB4 | integrin, beta 4 | 0.272 | Human | |
COMP | cartilage oligomeric matrix protein | 0.271 | Human | |
EHD2 | EH-domain containing 2 | 0.270 | ||
SH2B3 | SH2B adaptor protein 3 | 0.269 | Fly | |
PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.268 | ||
TWIST1 | twist homolog 1 (Drosophila) | 0.267 | ||
HAS2 | hyaluronan synthase 2 | 0.267 | Zebrafish | |
BMPR1B | bone morphogenetic protein receptor, type IB | 0.266 | ||
SH3RF1 | SH3 domain containing ring finger 1 | 0.266 | ||
PTH1R | parathyroid hormone 1 receptor | 0.262 | ||
MFAP4 | microfibrillar-associated protein 4 | 0.262 | Human | |
GATA4 | GATA binding protein 4 | 0.261 | Mouse Rat | |
SH3BP2 | SH3-domain binding protein 2 | 0.261 | ||
FST | follistatin | 0.261 | ||
FOXA2 | forkhead box A2 | 0.261 | Human | |
C1QC | complement component 1, q subcomponent, C chain | 0.261 | Human | |
CALD1 | caldesmon 1 | 0.261 | ||
RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.260 | Human | |
DMWD | dystrophia myotonica, WD repeat containing | 0.260 | ||
EGF | epidermal growth factor | 0.259 | ||
CRLF1 | cytokine receptor-like factor 1 | 0.258 | ||
SOCS2 | suppressor of cytokine signaling 2 | 0.258 | ||
NR0B2 | nuclear receptor subfamily 0, group B, member 2 | 0.256 | ||
FOSL1 | FOS-like antigen 1 | 0.256 | Human | |
AHCTF1 | AT hook containing transcription factor 1 | 0.256 | ||
NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.255 | ||
ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.255 | ||
DUSP9 | dual specificity phosphatase 9 | 0.255 | ||
LMNA | lamin A/C | 0.254 | ||
TTR | transthyretin | 0.254 | ||
INHBB | inhibin, beta B | 0.254 | ||
APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 | 0.254 | ||
PLXDC1 | plexin domain containing 1 | 0.252 | ||
EPHB2 | EPH receptor B2 | 0.252 | Human Mouse | |
ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.252 | ||
ITGA7 | integrin, alpha 7 | 0.249 | Human | |
TNC | tenascin C | 0.249 | ||
UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.248 | ||
DAXX | death-domain associated protein | 0.247 | ||
LRP1 | low density lipoprotein receptor-related protein 1 | 0.247 | Human Mouse | |
PKM2 | pyruvate kinase, muscle | 0.247 | ||
SOX2 | SRY (sex determining region Y)-box 2 | 0.246 | Human | |
PRRX2 | paired related homeobox 2 | 0.245 | ||
AHNAK | AHNAK nucleoprotein | 0.245 | ||
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.244 | ||
CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.244 | Human | |
BDNF | brain-derived neurotrophic factor | 0.244 | Human | |
DLG4 | discs, large homolog 4 (Drosophila) | 0.244 | Fly | |
MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.244 | ||
MECP2 | methyl CpG binding protein 2 (Rett syndrome) | 0.242 | ||
SH3PXD2A | SH3 and PX domains 2A | 0.242 | ||
FOXF2 | forkhead box F2 | 0.242 | ||
FZD8 | frizzled homolog 8 (Drosophila) | 0.242 | ||
COL18A1 | collagen, type XVIII, alpha 1 | 0.241 | ||
SH3GL2 | SH3-domain GRB2-like 2 | 0.240 | ||
EPHB3 | EPH receptor B3 | 0.240 | ||
SPEN | spen homolog, transcriptional regulator (Drosophila) | 0.240 | Fly | |
CD34 | CD34 molecule | 0.238 | ||
IER2 | immediate early response 2 | 0.237 | ||
MAPK10 | mitogen-activated protein kinase 10 | 0.237 | Human | |
EFNB2 | ephrin-B2 | 0.237 | ||
WNT3A | wingless-type MMTV integration site family, member 3A | 0.237 | Human | |
THY1 | Thy-1 cell surface antigen | 0.237 | ||
FGFR4 | fibroblast growth factor receptor 4 | 0.237 | ||
FBXW11 | F-box and WD repeat domain containing 11 | 0.236 | Fly | |
PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.236 | ||
INPPL1 | inositol polyphosphate phosphatase-like 1 | 0.236 | Rat | |
SLIT2 | slit homolog 2 (Drosophila) | 0.235 | ||
EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.235 | ||
SUMO3 | SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) | 0.234 | ||
ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.234 | ||
EDN3 | endothelin 3 | 0.234 | ||
ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.234 | ||
DDX21 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 | 0.233 | ||
ITGA6 | integrin, alpha 6 | 0.233 | Human | |
SPRY2 | sprouty homolog 2 (Drosophila) | 0.233 | Mouse Fly | |
GH2 | growth hormone 2 | 0.233 | Human | |
MYOD1 | myogenic differentiation 1 | 0.232 | ||
CLASP1 | cytoplasmic linker associated protein 1 | 0.231 | ||
RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.231 | Mouse | |
MED15 | mediator complex subunit 15 | 0.231 | ||
DPT | dermatopontin | 0.230 | ||
FGF4 | fibroblast growth factor 4 | 0.229 | ||
PNPLA6 | patatin-like phospholipase domain containing 6 | 0.228 | ||
PEA15 | phosphoprotein enriched in astrocytes 15 | 0.228 | ||
NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.228 | ||
HTR2C | 5-hydroxytryptamine (serotonin) receptor 2C | 0.226 | Human | |
PTPN21 | protein tyrosine phosphatase, non-receptor type 21 | 0.226 | ||
DAPK1 | death-associated protein kinase 1 | 0.226 | ||
LOXL1 | lysyl oxidase-like 1 | 0.225 | ||
EGR3 | early growth response 3 | 0.225 | ||
STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.225 | Worm Fly | |
EFNB1 | ephrin-B1 | 0.224 | Human | |
SOD3 | superoxide dismutase 3, extracellular | 0.224 | ||
CLTC | clathrin, heavy chain (Hc) | 0.224 | ||
HMGA2 | high mobility group AT-hook 2 | 0.223 | ||
CUL1 | cullin 1 | 0.219 | Fly | |
STMN2 | stathmin-like 2 | 0.219 | ||
PUM1 | pumilio homolog 1 (Drosophila) | 0.218 | Fly | |
FNBP1 | formin binding protein 1 | 0.218 | ||
EGR1 | early growth response 1 | 0.218 | Mouse | |
HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B | 0.218 | Human | |
SOX10 | SRY (sex determining region Y)-box 10 | 0.217 | Human | |
CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.217 | ||
CBLB | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 0.216 | Human Fly | |
DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) | 0.216 | ||
CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.216 | ||
DDX3X | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 0.216 | ||
SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.215 | ||
DUSP7 | dual specificity phosphatase 7 | 0.215 | ||
IL11 | interleukin 11 | 0.214 | ||
PRRX1 | paired related homeobox 1 | 0.214 | ||
ATF7IP | activating transcription factor 7 interacting protein | 0.214 | ||
COL8A1 | collagen, type VIII, alpha 1 | 0.213 | ||
RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.213 | Human | |
HDAC6 | histone deacetylase 6 | 0.212 | ||
COL14A1 | collagen, type XIV, alpha 1 | 0.212 | ||
TBXA2R | thromboxane A2 receptor | 0.212 | ||
FOXF1 | forkhead box F1 | 0.211 | ||
WT1 | Wilms tumor 1 | 0.211 | ||
PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.210 | ||
DMPK | dystrophia myotonica-protein kinase | 0.209 | ||
PTHLH | parathyroid hormone-like hormone | 0.208 | ||
KLF4 | Kruppel-like factor 4 (gut) | 0.207 | ||
WRN | Werner syndrome, RecQ helicase-like | 0.207 | ||
LEP | leptin | 0.206 | ||
FGB | fibrinogen beta chain | 0.206 | Human | |
FES | feline sarcoma oncogene | 0.205 | Human | |
ANKRD17 | ankyrin repeat domain 17 | 0.205 | Fly | |
HEY1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.205 | ||
SYNRG | synergin, gamma | 0.205 | ||
FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.204 | ||
ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.204 | Human | |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.203 | Human | |
RUNX1 | runt-related transcription factor 1 | 0.203 | ||
F3 | coagulation factor III (thromboplastin, tissue factor) | 0.203 | ||
DUSP3 | dual specificity phosphatase 3 | 0.202 | ||
MYO10 | myosin X | 0.202 | ||
PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.201 | ||
CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.201 | ||
SEC23A | Sec23 homolog A (S. cerevisiae) | 0.201 | ||
MYH9 | myosin, heavy chain 9, non-muscle | 0.200 | ||
STRADA | STE20-related kinase adaptor alpha | 0.199 | ||
SOX21 | SRY (sex determining region Y)-box 21 | 0.199 | ||
CHUK | conserved helix-loop-helix ubiquitous kinase | 0.198 | ||
FGF10 | fibroblast growth factor 10 | 0.198 | ||
HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | 0.197 | ||
FGFR3 | fibroblast growth factor receptor 3 | 0.196 | ||
MMP19 | matrix metallopeptidase 19 | 0.196 | ||
CYR61 | cysteine-rich, angiogenic inducer, 61 | 0.196 | ||
MBP | myelin basic protein | 0.196 | ||
PTPRF | protein tyrosine phosphatase, receptor type, F | 0.195 | Human Rat | |
LEFTY1 | left-right determination factor 1 | 0.195 | ||
WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.194 | Mouse | |
SLC18A3 | solute carrier family 18 (vesicular acetylcholine), member 3 | 0.194 | ||
DOK6 | docking protein 6 | 0.193 | Human | |
FXYD1 | FXYD domain containing ion transport regulator 1 | 0.193 | ||
ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.192 | ||
SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.192 | ||
ECM1 | extracellular matrix protein 1 | 0.192 | ||
PLEC | plectin | 0.192 | ||
CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.192 | ||
C19orf50 | chromosome 19 open reading frame 50 | 0.191 | ||
OSMR | oncostatin M receptor | 0.191 | Human | |
DAB1 | disabled homolog 1 (Drosophila) | 0.190 | Human | |
ZFP36L1 | zinc finger protein 36, C3H type-like 1 | 0.190 | ||
ARID1A | AT rich interactive domain 1A (SWI-like) | 0.190 | ||
CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 | 0.190 | ||
IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.190 | ||
FMOD | fibromodulin | 0.188 | Human | |
USP22 | ubiquitin specific peptidase 22 | 0.188 | ||
IL1RAP | interleukin 1 receptor accessory protein | 0.187 | ||
FOXO1 | forkhead box O1 | 0.186 | Human Mouse Worm Fly | |
MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.186 | Fly | |
NPTN | neuroplastin | 0.186 | Rat | |
APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.185 | Mouse | |
MSX2 | msh homeobox 2 | 0.185 | Mouse | |
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.184 | ||
JAK3 | Janus kinase 3 | 0.184 | Human Mouse | |
SEC24B | SEC24 family, member B (S. cerevisiae) | 0.184 | ||
LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.184 | ||
PRPF4B | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 0.184 | ||
RUNX2 | runt-related transcription factor 2 | 0.183 | Mouse | |
RAB14 | RAB14, member RAS oncogene family | 0.183 | Mouse | |
TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.183 | ||
USP9X | ubiquitin specific peptidase 9, X-linked | 0.183 | ||
WNT7A | wingless-type MMTV integration site family, member 7A | 0.183 | Human | |
CD9 | CD9 molecule | 0.183 | ||
NOXA1 | NADPH oxidase activator 1 | 0.183 | ||
PTPRD | protein tyrosine phosphatase, receptor type, D | 0.183 | Human | |
HSF1 | heat shock transcription factor 1 | 0.182 | ||
GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.182 | ||
STAB1 | stabilin 1 | 0.181 | ||
CD59 | CD59 molecule, complement regulatory protein | 0.180 | Mouse | |
SPDEF | SAM pointed domain containing ets transcription factor | 0.180 | ||
PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.180 | ||
VCL | vinculin | 0.180 | ||
FBXO11 | F-box protein 11 | 0.180 | ||
EPHA3 | EPH receptor A3 | 0.180 | ||
ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.179 | ||
ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.179 | ||
MXRA8 | matrix-remodelling associated 8 | 0.178 | ||
MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | 0.178 | ||
FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.178 | ||
RECK | reversion-inducing-cysteine-rich protein with kazal motifs | 0.177 | ||
NLK | nemo-like kinase | 0.177 | ||
SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.176 | ||
ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.176 | Human | |
PPP1R15A | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.176 | ||
SOX1 | SRY (sex determining region Y)-box 1 | 0.175 | Human | |
STAMBP | STAM binding protein | 0.175 | ||
ALX4 | ALX homeobox 4 | 0.175 | ||
CSNK1D | casein kinase 1, delta | 0.174 | ||
TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | 0.174 | ||
SNAI2 | snail homolog 2 (Drosophila) | 0.174 | ||
ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.172 | ||
ING2 | inhibitor of growth family, member 2 | 0.172 | ||
DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.172 | ||
TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.171 | Human | |
CSH2 | chorionic somatomammotropin hormone 2 | 0.171 | Human | |
MYB | v-myb myeloblastosis viral oncogene homolog (avian) | 0.170 | ||
NEUROG2 | neurogenin 2 | 0.170 | ||
COL11A1 | collagen, type XI, alpha 1 | 0.170 | Human | |
NTF3 | neurotrophin 3 | 0.170 | ||
MIB1 | mindbomb homolog 1 (Drosophila) | 0.169 | ||
SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | 0.169 | ||
EFNB3 | ephrin-B3 | 0.168 | ||
NGFR | nerve growth factor receptor | 0.168 | Mouse | |
GPR124 | G protein-coupled receptor 124 | 0.168 | Mouse | |
AES | amino-terminal enhancer of split | 0.168 | ||
CORO1A | coronin, actin binding protein, 1A | 0.168 | ||
RFWD2 | ring finger and WD repeat domain 2 | 0.168 | ||
SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) | 0.168 | ||
ROR2 | receptor tyrosine kinase-like orphan receptor 2 | 0.167 | Human | |
CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | 0.167 | ||
PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.167 | ||
DSG2 | desmoglein 2 | 0.167 | ||
PDGFA | platelet-derived growth factor alpha polypeptide | 0.167 | ||
COL6A3 | collagen, type VI, alpha 3 | 0.167 | Human | |
SGMS1 | sphingomyelin synthase 1 | 0.166 | ||
YY1 | YY1 transcription factor | 0.165 | ||
HIC1 | hypermethylated in cancer 1 | 0.165 | ||
CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.164 | ||
EGR2 | early growth response 2 | 0.164 | ||
FBXO7 | F-box protein 7 | 0.163 | ||
GATA2 | GATA binding protein 2 | 0.163 | ||
DOCK1 | dedicator of cytokinesis 1 | 0.163 | ||
STC2 | stanniocalcin 2 | 0.163 | ||
ARHGAP9 | Rho GTPase activating protein 9 | 0.163 | ||
MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.163 | ||
RAB6A | RAB6A, member RAS oncogene family | 0.162 | ||
WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.162 | Human | |
PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.161 | ||
COL10A1 | collagen, type X, alpha 1 | 0.161 | ||
FGF3 | fibroblast growth factor 3 | 0.161 | ||
PROX1 | prospero homeobox 1 | 0.161 | ||
PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.160 | Mouse | |
FZD1 | frizzled homolog 1 (Drosophila) | 0.160 | Mouse | |
OAF | OAF homolog (Drosophila) | 0.160 | ||
NBN | nibrin | 0.160 | ||
CHMP4B | chromatin modifying protein 4B | 0.160 | ||
KIAA1199 | KIAA1199 | 0.160 | ||
PGF | placental growth factor | 0.160 | Human | |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.159 | ||
PDLIM4 | PDZ and LIM domain 4 | 0.159 | ||
NRP2 | neuropilin 2 | 0.158 | Human Zebrafish | |
SMG1 | SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) | 0.158 | ||
ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.158 | ||
MGP | matrix Gla protein | 0.158 | ||
WIF1 | WNT inhibitory factor 1 | 0.157 | ||
FYB | FYN binding protein | 0.157 | ||
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.157 | ||
CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.157 | ||
GAST | gastrin | 0.157 | ||
SFRP5 | secreted frizzled-related protein 5 | 0.156 | ||
MFAP5 | microfibrillar associated protein 5 | 0.156 | ||
DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.156 | ||
KCNJ4 | potassium inwardly-rectifying channel, subfamily J, member 4 | 0.156 | Fly | |
RYK | RYK receptor-like tyrosine kinase | 0.156 | ||
CCDC6 | coiled-coil domain containing 6 | 0.156 | ||
ITGB5 | integrin, beta 5 | 0.156 | ||
SLIT3 | slit homolog 3 (Drosophila) | 0.155 | ||
AQP1 | aquaporin 1 (Colton blood group) | 0.155 | ||
PKP3 | plakophilin 3 | 0.155 | ||
LIN7B | lin-7 homolog B (C. elegans) | 0.155 | ||
EDN1 | endothelin 1 | 0.155 | ||
ADAM17 | ADAM metallopeptidase domain 17 | 0.155 | ||
RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.155 | Rat | |
EFR3A | EFR3 homolog A (S. cerevisiae) | 0.155 | ||
CDX2 | caudal type homeobox 2 | 0.154 | ||
GAS1 | growth arrest-specific 1 | 0.154 | ||
STAT4 | signal transducer and activator of transcription 4 | 0.154 | Human | |
ZMYM4 | zinc finger, MYM-type 4 | 0.154 | ||
SDC1 | syndecan 1 | 0.153 | ||
SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.153 | ||
GDNF | glial cell derived neurotrophic factor | 0.152 | ||
SON | SON DNA binding protein | 0.152 | ||
SLC38A2 | solute carrier family 38, member 2 | 0.152 | ||
LAMB3 | laminin, beta 3 | 0.151 | ||
NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.151 | ||
TWIST2 | twist homolog 2 (Drosophila) | 0.151 | ||
ASPN | asporin | 0.151 | ||
CSH1 | chorionic somatomammotropin hormone 1 (placental lactogen) | 0.150 | Human | |
LDLR | low density lipoprotein receptor | 0.150 | ||
AKAP12 | A kinase (PRKA) anchor protein 12 | 0.149 | ||
MESDC2 | mesoderm development candidate 2 | 0.149 | ||
PLXNB1 | plexin B1 | 0.149 | ||
ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.148 | ||
SPRY4 | sprouty homolog 4 (Drosophila) | 0.148 | Zebrafish Fly | |
SHH | sonic hedgehog | 0.148 | ||
CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.148 | ||
HSPG2 | heparan sulfate proteoglycan 2 | 0.148 | Worm | |
ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.147 | ||
RELN | reelin | 0.147 | ||
DLK1 | delta-like 1 homolog (Drosophila) | 0.147 | ||
CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.147 | ||
SH2B2 | SH2B adaptor protein 2 | 0.146 | ||
IRF3 | interferon regulatory factor 3 | 0.146 | ||
CMTM8 | CKLF-like MARVEL transmembrane domain containing 8 | 0.146 | ||
C1QL1 | complement component 1, q subcomponent-like 1 | 0.146 | Human | |
NF2 | neurofibromin 2 (merlin) | 0.146 | Fly | |
FNDC1 | fibronectin type III domain containing 1 | 0.146 | ||
COL5A3 | collagen, type V, alpha 3 | 0.145 | Human | |
F2RL3 | coagulation factor II (thrombin) receptor-like 3 | 0.145 | ||
STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.145 | Human | |
MAGEF1 | melanoma antigen family F, 1 | 0.145 | ||
SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | 0.145 | ||
FOXC1 | forkhead box C1 | 0.145 | Human Mouse | |
RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 0.144 | Human | |
PTPRE | protein tyrosine phosphatase, receptor type, E | 0.144 | Mouse Rat | |
EPHB4 | EPH receptor B4 | 0.144 | ||
RTN4 | reticulon 4 | 0.144 | ||
PRKCE | protein kinase C, epsilon | 0.144 | Worm | |
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.144 | ||
IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.144 | ||
MEF2C | myocyte enhancer factor 2C | 0.143 | ||
COL5A2 | collagen, type V, alpha 2 | 0.142 | Human | |
EPHA1 | EPH receptor A1 | 0.142 | ||
RAP1A | RAP1A, member of RAS oncogene family | 0.142 | ||
CDCP1 | CUB domain containing protein 1 | 0.142 | ||
PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.142 | ||
MTF2 | metal response element binding transcription factor 2 | 0.141 | ||
GLI3 | GLI family zinc finger 3 | 0.141 | ||
HEG1 | HEG homolog 1 (zebrafish) | 0.141 |