IMP: Integrative Multi-species Prediction

Homo sapiens

25 genes annotated in human

Multi-species View

cell cell junction assembly

GO:0007043

The aggregation, arrangement and bonding together of a set of components to form a junction between cells.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell cell junction assembly"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cell cell junction assembly" (in gray)

Name	Description	Probability	Func Analog Organism
SFN	stratifin	0.975
NCF1	neutrophil cytosolic factor 1	0.939
TJP2	tight junction protein 2 (zona occludens 2)	0.856
APC	adenomatous polyposis coli	0.749
TJP1	tight junction protein 1 (zona occludens 1)	0.654	Fly
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.503	Mouse
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.473	Human Fly
DSP	desmoplakin	0.382
LCK	lymphocyte-specific protein tyrosine kinase	0.348	Fly
JUP	junction plakoglobin	0.282
GDA	guanine deaminase	0.275
ACTB	actin, beta	0.200
F11R	F11 receptor	0.184
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.179	Human
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.179	Human
JUB	jub, ajuba homolog (Xenopus laevis)	0.162
ARHGAP10	Rho GTPase activating protein 10	0.145
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.145
RHOA	ras homolog gene family, member A	0.142
EGFR	epidermal growth factor receptor	0.136
TFRC	transferrin receptor (p90, CD71)	0.118
TRIP6	thyroid hormone receptor interactor 6	0.116
DSG2	desmoglein 2	0.104
FYN	FYN oncogene related to SRC, FGR, YES	0.103	Fly
PKP4	plakophilin 4	0.096	Human Mouse
INADL	InaD-like (Drosophila)	0.095
CTNND1	catenin (cadherin-associated protein), delta 1	0.094	Human
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.093	Human Mouse
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.090
LAD1	ladinin 1	0.089
MARK3	MAP/microtubule affinity-regulating kinase 3	0.088
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.085	Fly
PSEN1	presenilin 1	0.080
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.079
CD81	CD81 molecule	0.074
PKP3	plakophilin 3	0.071
RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8	0.068
PKP2	plakophilin 2	0.067
ARHGAP1	Rho GTPase activating protein 1	0.067
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.067
MKL1	megakaryoblastic leukemia (translocation) 1	0.062
CD63	CD63 molecule	0.061
GJA1	gap junction protein, alpha 1, 43kDa	0.057
KRT14	keratin 14	0.056
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.052
HCK	hemopoietic cell kinase	0.050	Fly
TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.048
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.047
STRN3	striatin, calmodulin binding protein 3	0.045
TUBGCP4	tubulin, gamma complex associated protein 4	0.043
ADAM17	ADAM metallopeptidase domain 17	0.043
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.042
YAP1	Yes-associated protein 1	0.042
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.042
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.041
NCK1	NCK adaptor protein 1	0.040
KRT18	keratin 18	0.037
UBASH3B	ubiquitin associated and SH3 domain containing B	0.037
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.035	Rat Fly
PFN1	profilin 1	0.034
TNS4	tensin 4	0.034
TRIM29	tripartite motif containing 29	0.033
SDC2	syndecan 2	0.033
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.033
RABIF	RAB interacting factor	0.032
PKN2	protein kinase N2	0.032
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.031
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.030
SORBS3	sorbin and SH3 domain containing 3	0.030
MYH9	myosin, heavy chain 9, non-muscle	0.029
FERMT2	fermitin family member 2	0.029
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.028
ZNF282	zinc finger protein 282	0.028
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.027
HDAC7	histone deacetylase 7	0.027	Mouse
ACTN1	actinin, alpha 1	0.027
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.026
PDCD10	programmed cell death 10	0.026
TLN1	talin 1	0.026
BAD	BCL2-associated agonist of cell death	0.026
SH3GL1	SH3-domain GRB2-like 1	0.025
ARHGAP26	Rho GTPase activating protein 26	0.025
CFL1	cofilin 1 (non-muscle)	0.024
DLG4	discs, large homolog 4 (Drosophila)	0.024	Human Worm
SH2D3A	SH2 domain containing 3A	0.024
FLNA	filamin A, alpha	0.024
PRKD2	protein kinase D2	0.024
RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	0.024
SH3KBP1	SH3-domain kinase binding protein 1	0.023
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.022
STK24	serine/threonine kinase 24	0.022	Fly
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.022	Fly
CXCR5	chemokine (C-X-C motif) receptor 5	0.022
KRT8	keratin 8	0.022
CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	0.021
SYK	spleen tyrosine kinase	0.020
ZYX	zyxin	0.020
SHROOM3	shroom family member 3	0.020
GAS7	growth arrest-specific 7	0.020
MARK2	MAP/microtubule affinity-regulating kinase 2	0.019
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.019
EZR	ezrin	0.018
FAM40B	family with sequence similarity 40, member B	0.018
SNX33	sorting nexin 33	0.018
WDYHV1	WDYHV motif containing 1	0.018
MAPK12	mitogen-activated protein kinase 12	0.018
GYPC	glycophorin C (Gerbich blood group)	0.018
EPS8	epidermal growth factor receptor pathway substrate 8	0.017
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	0.017
GIPC1	GIPC PDZ domain containing family, member 1	0.017
BTK	Bruton agammaglobulinemia tyrosine kinase	0.017
PRKCA	protein kinase C, alpha	0.017
PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	0.017
ERBB2IP	erbb2 interacting protein	0.017	Worm
ERRFI1	ERBB receptor feedback inhibitor 1	0.016
VMP1	vacuole membrane protein 1	0.016
AMOTL2	angiomotin like 2	0.016
LIN7A	lin-7 homolog A (C. elegans)	0.016
GCC1	GRIP and coiled-coil domain containing 1	0.016
STRN4	striatin, calmodulin binding protein 4	0.015
RHPN2	rhophilin, Rho GTPase binding protein 2	0.015
GJD3	gap junction protein, delta 3, 31.9kDa	0.015
DPYSL4	dihydropyrimidinase-like 4	0.015
RND3	Rho family GTPase 3	0.015
GPRIN2	G protein regulated inducer of neurite outgrowth 2	0.015
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.015
PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)	0.015	Fly
C1orf106	chromosome 1 open reading frame 106	0.014
RACGAP1	Rac GTPase activating protein 1	0.014
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.014	Fly
AKIP1	A kinase (PRKA) interacting protein 1	0.014
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.014
PRKCD	protein kinase C, delta	0.014
NEK6	NIMA (never in mitosis gene a)-related kinase 6	0.014
CDH5	cadherin 5, type 2 (vascular endothelium)	0.014
SHCBP1	SHC SH2-domain binding protein 1	0.014
ACTN4	actinin, alpha 4	0.014	Mouse
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.014
MYOCD	myocardin	0.013
ENG	endoglin	0.013
FRMD5	FERM domain containing 5	0.013
RGS14	regulator of G-protein signaling 14	0.013	Fly
ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16	0.013
KRT17	keratin 17	0.013
HDAC5	histone deacetylase 5	0.013
STK25	serine/threonine kinase 25	0.013	Fly
TRIM9	tripartite motif containing 9	0.013
CGN	cingulin	0.012	Mouse
RYR2	ryanodine receptor 2 (cardiac)	0.012
SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5	0.012
AKAP11	A kinase (PRKA) anchor protein 11	0.012
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.012
PDLIM1	PDZ and LIM domain 1	0.012
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.012
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.012
RHOG	ras homolog gene family, member G (rho G)	0.012
MYOG	myogenin (myogenic factor 4)	0.012
ARHGEF5	Rho guanine nucleotide exchange factor (GEF) 5	0.011
CTTNBP2NL	CTTNBP2 N-terminal like	0.011
DSC2	desmocollin 2	0.011	Zebrafish
KRT5	keratin 5	0.011
GSK3B	glycogen synthase kinase 3 beta	0.011
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.011	Mouse
EGR1	early growth response 1	0.011
MCC	mutated in colorectal cancers	0.011
ARHGAP21	Rho GTPase activating protein 21	0.011
RHOC	ras homolog gene family, member C	0.011
ARHGAP29	Rho GTPase activating protein 29	0.011
OPTN	optineurin	0.010
CTTN	cortactin	0.010
PLD1	phospholipase D1, phosphatidylcholine-specific	0.010
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.010
MARK1	MAP/microtubule affinity-regulating kinase 1	0.010
ITGA6	integrin, alpha 6	0.010
NCF4	neutrophil cytosolic factor 4, 40kDa	0.010
SORBS2	sorbin and SH3 domain containing 2	0.010
MPRIP	myosin phosphatase Rho interacting protein	0.010
WASF2	WAS protein family, member 2	0.010
PXN	paxillin	0.010
CADM1	cell adhesion molecule 1	0.010